... territorial concessions from Kuwait to cover approaches to Um Qasr. Proposed port on Khor Abdullah at Um Qasr, Persian Gulf. 16/02/1940. FO 371/ ...
1940 - Gale Group | ArchivesUnbound Iraq
Federica Geremicca, Melissa M. Bilec,
... delves into the integration prospects of Urban Metabolism (UM) with industry 4.0 technologies, particularly digital twin ( ... scope of this review was to determine how UM results are represented to end users, such as ... align with industry practices. Initially, we analyzed 70 UM studies to investigate the methods and visualization techniques employed. Trends revealed minimal integration of UM with Industry 4.0 technologies or DTs. The ... lack of dynamic and geographically oriented visualization in UM, with static representation methods like bar charts and ...
Tópico(s): Building Energy and Comfort Optimization
2024 - Elsevier BV | Sustainable Cities and Society
Cover title: Papiergeld, durch Getraidevorräthe verbürgt ... Errata at end of text. Book.
0000 - Gale Group | The Making of Modern World
Gillian Young McCusker, Jutta Vüllers, Peggy Achtert, Paul Field, Jonathan J. Day, Richard Forbes, Ruth Price, Ewan O’Connor, Michael Tjernström, John Prytherch, Ryan R. Neely, Ian M. Brooks,
... evaluate how well the Met Office Unified Model (UM) and the European Centre for Medium-Range Weather ... nested limited-area model (LAM) configuration of the UM – two regionally operational single-moment schemes (UM_RA2M and UM_RA2T) and one novel double-moment scheme (UM_CASIM-100) – while one global simulation was conducted ... were identified across both models, with both the UM and IFS overestimating cloud occurrence below 3 km. ... across the three cloud configurations used within the UM framework, with >90 % mean cloud occurrence simulated between ...
Tópico(s): Atmospheric aerosols and clouds
2023 - Copernicus Publications | Atmospheric chemistry and physics
Book.
0000 - Gale Group | The Making of Modern World
Jingting Luo, Haowen Li, Jingying Xiu, Jingyao Zeng, Zhaoxun Feng, Hanqing Zhao, Yang Li, Wenbin Wei,
Uveal melanoma (UM) is the most common intraocular malignancy in adults, with a poor survival prognosis. To date, limited understanding of UM's molecular mechanisms constitutes an obstacle to developing ... In this study, we examined key regulators mediating UM progression and their clinical relevance.Transcriptomics of UM patients and cells were analyzed via RNA sequencing ... ZNF704) was identified as prognosis-related biomarker for UM based on clinical characteristics and RNA-seq data ... analysis identified ZNF704 as a novel biomarker of UM. Prognostic analysis indicated ZNF704 as an independent predictor ...
Tópico(s): interferon and immune responses
2023 - BioMed Central | Biomarker Research
OAPEN Free
Book.
0000 - Gale Group | The Making of Modern World
Arwin Groenewoud, Jie Yin, Maria C. Gelmi, Samar Alsafadi, Fariba Némati, Didier Decaudin, Sergio Román-Román, Helen Kalirai, Sarah E. Coupland, Aart G. Jochemsen, Martine J. Jager, Felix B. Engel, B. Ewa Snaar‐Jagalska,
Uveal melanoma (UM) has a high risk to progress to metastatic disease with a median survival of 3.9 months after metastases detection, as metastatic UM responds poorly to conventional and targeted chemotherapy and ... immunotherapy. Here, we present a patient-derived zebrafish UM xenograft model mimicking metastatic UM. Cells isolated from Xmm66 spheroids derived from metastatic UM patient material were injected into 2 days-old ... spheroid cultures from 14 metastatic and 10 primary UM tissues, which were used for xenografts with a ...
Tópico(s): interferon and immune responses
2023 - Springer Nature | Cell Death Discovery
Directory of Open Access Books (DOAB)
Edited by Magnús Ketilson. Book.
0000 - Gale Group | The Making of Modern World
Jian-Lan Liu, Pengpeng Zhang, Fang Yang, Keyu Jiang, Shiyi Sun, Zhijia Xia, Gang Yao, Jian Tang,
... of glycosylation-related genes (GRGs) in uveal melanoma (UM) is yet to be fully understood. This study ... shed light on the impact of GRGs on UM prognosis.To identify the most influential genes in UM, we employed the AUCell and WGCNA algorithms. The ... integrating bulk RNA-seq and scRNA-seq data. UM patients were separated into two groups based on ... The role of the critical gene AUP1 in UM was validated through in vitro and in vivo ... The GCNS was a significant prognostic factor for UM, and high GCNS correlated with poorer outcomes. Patients ...
Tópico(s): Ubiquitin and proteasome pathways
2023 - Frontiers Media | Frontiers in Endocrinology
Directory of Open Access Books (DOAB)
... on port. Proposed port on Khor Abdullah at Um Qasr, Persian Gulf. 29/04/1940. FO 371/ ...
1940 - Gale Group | ArchivesUnbound Iraq
Martin Holtmann, Gerd Lehmkuhl, Paul L. Plener, Michael Kölch,
... Organization (WHO), die eine Zunahme der depressiven Erkrankungen um 27.6 % und der Angsterkrankungen um 25.6 % berichtet (World Health Organization, 2022). In ... Zunahme an Vorstellungen aufgrund von Suizidversuchen in Notaufnahmen um 51 % bei weiblichen Jugendlichen in den USA berichtet ( ... Nutzung von sozialen Medien und Computerspielen zumindest vorübergehend um 40 bis 50 % an (DAK-Gesundheit, 2021). Basierend ... Bildschirmzeit während der Pandemie bei Kindern und Jugendlichen um 52 % gestiegen ist (Madigan, Eirich, Pador, McArthur & Neville, ...
Tópico(s): Tryptophan and brain disorders
2023 - Hogrefe Verlag | Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie
L. Schrank, Dr. E. Hornig, Wiener Zig,
Essay: Unterstützungsball, Abnorme Lichterscheinungen Um Dunkle Gegenstände in Positivbildern, Officielle Ausstellungsberichte, Miscellen Sonnenfinsternissphotographien, Die Retouche Der Photograhie Das Coloriren Auf Albumin, Vorträge Über Photographische Chemie ...
1869 - Gale Group | NCCO Photography
Carlos E. Iglesias‐Aguirre, Antonio González‐Sarrías, Adrián Cortés‐Martín, María Romo‐Vaquero, Leire Osuna‐Galisteo, J. M. Castro Cerón, Juan Carlos Espı́n, María V. Selma,
... the different Uro metabolites. Three human urolithin metabotypes (UM-A, UM-B, and UM-0) based on dissimilar Uro production profiles have ... acid metabolism to yield the urolithin-producing metabotypes (UM-A and UM-B) in vitro have been identified. However, the ... bacterial consortia to customize urolithin production to mimic UM-A and UM-B in vivo is still unknown. In the ... to colonize the intestine of rats and convert UM-0 (Uro non-producers) animals into Uro-producers that mimic UM-A and UM-B, respectively. Two consortia of ...
Tópico(s): Cynara cardunculus studies
2023 - Royal Society of Chemistry | Food & Function
Miscellaneous Free eBooks
... Persian Gulf. Proposed port on Khor Abdullah at Um Qasr, Persian Gulf. 20/03/1940. FO 371/ ...
1940 - Gale Group | ArchivesUnbound Iraq
Produção Nacional
Revisado por pares
Lucimara de Sousa Teixeira, Dalva Célia Henriques Rocha Guazzelli,
... seguir, de modo breve, à essência de cada um deles. No capítulo 1 intitulado “Os avanços, as ... abordam a cibercultura, o direito à comunicação como um exercício da cidadania, o compartilhamento e a liberdade ... como recurso e estratégia metodológicas no desenvolvimento de um projeto voltado para a sustentabilidade na educação ambiental. ... Baseados em Projetos (ABP) como o centro de um projeto que relaciona o homem com a natureza, ... adultos nas questões ambientais. As autoras reforçam que um projeto pode envolver a multidisciplinaridade, como chave de ...
Tópico(s): Education during COVID-19 pandemic
2023 - UNIVERSIDADE NOVE DE JULHO | EccoS – Revista Científica
Directory of Open Access Books (DOAB)
... kept informed. Proposed port on Khor Abdullah at Um Qasr, Persian Gulf. 08/04/1940. FO 371/ ...
1940 - Gale Group | ArchivesUnbound Iraq
Anna Han, Vivian Chua, Usman Baqai, Timothy J. Purwin, Nelisa Bechtel, Emily Hunter, Manoela Tiago, Erin L. Seifert, David W. Speicher, Zachary T. Schug, J. William Harbour, Andrew E. Aplin,
... therapeutic options are still lacking for uveal melanoma (UM) patients who develop metastasis. Metastatic traits of UM are linked to BRCA1-associated protein 1 (BAP1) mutations. Cell metabolism is re-programmed in UM with BAP1 mutant UM, but the underlying mechanisms and opportunities for therapeutic intervention remain unclear. BAP1 mutant UM tumors have an elevated glycolytic gene expression signature, ... complex and PDH kinase (PDHK1). Furthermore, BAP1 mutant UM cells showed higher levels of phosphorylated PDHK1 and ...
Tópico(s): Microtubule and mitosis dynamics
2022 - Springer Nature | Oncogene
Directory of Open Access Books (DOAB)
... from Kuwait. Proposed port on Khor Abdullah at Um Qasr, Persian Gulf. 27/02/1940. FO 371/ ...
1940 - Gale Group | ArchivesUnbound Iraq
Grace B. Phelps, Hannah R. Hagen, Adam Amsterdam, Jacqueline A. Lees,
Cutaneous melanoma (CM) and uveal melanoma (UM) both originate from the melanocytic lineage but are primarily driven by distinct oncogenic drivers, BRAF/NRAS or GNAQ/GNA11, respectively. The melanocytic ... CM development and maintenance, but its role in UM is largely unexplored. Here, we use zebrafish models to dissect the key UM oncogenic signaling events and establish the role of MITF in UM tumors. Using a melanocytic lineage expression system, we ... or its upstream CYSLTR2 receptor (CYSLTR2L129Q) both drive UM when combined with a cooperating mutation, tp53M214K/M214K. ...
Tópico(s): Ubiquitin and proteasome pathways
2022 - National Academy of Sciences | Proceedings of the National Academy of Sciences