Waldemar Januszczak, Kathryn O'Sullivan, David Mills, Sally Brock, V S, Dave Garnett, Joe Gonzalez, Professor Gideon Garter, Amanda Ursell, Professor Iain Moffat, Dominic O'Conneil, Alastair McCall, Neil Wormald, Benoit Pensivy, Peter Hepper, Dominic Bradbury, Susan Berger, Martin James, Jonathan Ungoed-Thomas, Russell Watson, Rosie Millard, Ian Crithley, David Hewson, Hugh Canning, Sarah Dempster, Peter Kellner, Peter Oliver, Holly Watt, Paul Gostick, Nicholas Hellen, Caroline Scott, Shelley Von Strunckel, Christopher Morgan, Brian Jackman, Janet Daley, Frank Field MP, Robbie Hudson, Michalene Wandor, Emma Smith, Richard Tang, Uzi Mahnaimi, S A, Bryan Appleyard, John Elliott, Maurice Chittenden, Richard Brooks Arts Editor, Martin Corry, Brendan Simms, Dan Box, Chris Haslam, John Carey, Mary Braid, Nick Fielding, Mark Kleinmen, Liam Clarke, Peter Schmeichel, Graham Norwood, David Budworth, William Lewis Business editor, Lewis Moody, Clive Hetherington, Stewart Mitchell, Neil Hanson, Sarah Baxter, Jason Dawe, Jonathan Northcroft, Gianfranco Zola, Hala Jaber, Bagshawe, John Smith, Mark C O'Flaherty, Jim Munro, Peter Whittle, D M, Colin Brennan, Andrew Longmore, Lesley White, Robert Slater, Peter Whittie, Lynda Bellingham, Terence Blacker, Lucy Hughes-Hallett, E P, Andrew Sullivan, Patricia Hewitt, John Hariow, Beth Rogers, Stuart Barnes, Peter Jones, Cally Law, Mark Edward, Victoria Segal, Gareth Chadwick, Edward Porter, Phil Spencer, Dave Pollard, Martin Rees, Pam Barren, Joe Loveiay, Jeff Potter, Waldemar Januszcrak, Pat Malone, Brendan Bourne, Christopher Silvester, Stuart Wavell, Paul Donovan, Zoe Thomas, Hugh McIlvanney, Steve Boyd, Jennifer Wilson, Angela Young, John Follain, Louise, Ben Tomkins, Stuart Andrews, David Leppard, Kim Cattrall, John Dugdals, Chris White, Douglas Dalby, Lois Rogers, Alan Combes, Eddle Pitman, David Cracknell, Jayesh Ghaghda, David Walton, Diana Wright, Peter Koenig, Barry Flatman, Natalie Graham, Jessica Brinton, David Walsh, Spindale, Sarah Keenlyside, Stephen Armstrong, Mark Macaskill, Bethan Cole, Richard Woods, James Meller, Ray Hutton, Martin Ivens, Ria Higgins, Dileep Premachandran, A A Gill, Brian Glanville, Jeremy Langmead, Daniel Emery, Nigel Powell, Roger Dobson, Chris Whyatt, Ben Dowell, John Aizlewood, Jeremy Lazell, Lois Rogers Medical Editor, Jonathan Futrell, Hugh Pearman, Tony Perrottet, Ross Tieman, Annobel Nielsen, Rachel De Thame, Sylvia Ann Hewlett, Victora Segal, Richard Lewis, Helen Stewart, Kevin Dunn, John Dugdale, William Kay, Barbara Hall, Jon Swain, Rob Hughes, John Peter, Donna Leon, Ralf Schumacher, Blowere, Kevin Platt, Marian Donlan, Ivo Tennant, David Smith, Tim Richards, Adelheid Gowrie, Henry Russell, Adrian Furnham, Nicholas Hellen Social Affairs Editor, Malcolm Chapman, Stewart Lee, Peter Conradi, Ronne Corbett, Michael Portillo, Alfred Kinsey, Richard Fletcher, Jeremy Guscott, Dan Drillsma-Milgrom, Maggie Gee, Sarah-Kate Templeton, Paul Kimmage, Chris Woodhead, Alex Clark, Mark Edwards, Rachel Bridge, Susan Clark, Nick Rodrigues, Sean Newsom, Raymond Keene, Zoe Brennan, Kipper Williams, Stephen Jones, Robert Rutledge, Jemima Khan, Louise Armitstead, Brian Deer, Nick Cain, Tim Moorey, S Silvers, Victoria Raymond, Victoria O'brien, Roland White, David Waim, Richard Rae, Mark Franchetti, Michael Sheridan, Tevor Lewis, Dipesh Gadher, John Waples, Hunter Davies, David Horspool, Stephen Pettitt, Karen MacGregor, Mark Hodson, Simon Kurs, Andrew Frankel, Joe Lovejoy, Dan Cairns, David Smith Economics Editor, Hugh Mason, Karen Robinson, Helena Frith Powell, Helen Davies, Kenny Farquharson, Christopher Somerville, Sandra Owen, Frank Whitford, Sybil Kapoor, Andrew Taylor, P D, Melanie Rickey, Tom Burkard, Martin Brundle, Simon Wilde, Irwin Stelzer, Peter Wilson, Simon Woodroffe, David Dougill, Captain Walter Eggert, Frank Graham, Bob Barbour, Jonathon Carr-Brown, Paul Forsyth, Simon Gray, Geraldine Hackett Education Correspondent, Jeremy Clarkson, David Cairns, Greg Struthers, Colin Marett, Christian Allen Purefoy, George Perry, Christopher Lamb, Paul Ham, Fiona Fleck, Frances Spalding, Roger Schofield, Jasper Gerard, Paul Driver, Chris West, Tilly, Ian Hawkey, Paul Durman, Askold Krushelnycky, Rod Liddle, Cosmo Landesman, Sharon Ridoynauth, Mark Lister, Dominic O'Connell, Andrew Holgate, Roger Cryer, Andrew Smith, Jerome Carroll, Caroline Donald, Annette Karmiloff-Smith, Colin McDowell, Christopher Goodwin, Shane Watson, Eric Carlin, Cllve Davis, Clare Francis, John Harlow, Joel Stewart, Mark Kleinman, Peter Jonson, Jessica Bown, Sally Kinnes, Naomi Caine, David Wickers, Colin Russell, Julian Nettlefold, Jean-Paul Flintoff, Andrew Davidson, Richard Caseby, Janie Omorogbe, Matthew Goodman, India Knight, Kingston Smith, Arton Davies, Kay Sharp,
... Adams hails steel band Forest savour away win Ugarte's high five as Wrexham hit six Repka ... Directions Swansea Cork Ferries Markwarner Miami's Hotel Victor (0845 888 1234, www. hyatt. com; … From April ...
2005 - Gale Group | Sunday Times HA GDA
Produção Nacional
Revisado por pares
Maria Fernanda de Souza Costa, Victor Ugarte Bornstein, André Luis Peixoto Candéa, Mariana Henriques, Maria das Graças Henriques, Carmen Penido,
Herein, we provide evidence that during allergic inflammation, CCL25 induces the selective migration of IL-17(+) γδ T cells mediated by α(4) β(7) integrin. Intrapleural injection of CCL25 into ovalbumin (OVA)-immunized C57BL/6 mice triggered the accumulation of γδ T lymphocytes expressing CCR9 (CCL25 receptor) and α(4) β(7) integrin in the pleura, but failed to attract αβ T lymphocytes. CCL25 attracted CCR6(+) γδ T cells producing IL-17 (but not IFN-γ or IL-4). OVA challenge triggered increased production ...
Tópico(s): Immunotherapy and Immune Responses
2012 - Wiley | European Journal of Immunology
V. ROLLESTON, , VICTOR MILWARD., THACKERAY TURNER., M., ROBERT N. CUST., LAWSON TAIT., H. C. BEETON, ,
... And Admiralty Division. Fernandes V. Fernandes And De Ugarté.. Property: Board And Residence, Apartments, &c., Sales By ...
1897 - Gale Group | TDA
Meimei Shan, Maurizio Gentile, John R. Yeiser, A. Walland, Victor Ugarte Bornstein, Kang Chen, Bing He, Linda Cassis, Anna Bigas, Montserrat Cols, Laura Comerma, Bihui Huang, J. Magarian Blander, Huabao Xiong, Lloyd Mayer, M. Cecilia Berin, Leonard H. Augenlicht, Anna Velcich, Andrea Cerutti,
A dense mucus layer in the large intestine prevents inflammation by shielding the underlying epithelium from luminal bacteria and food antigens. This mucus barrier is organized around the hyperglycosylated mucin MUC2. Here we show that the small intestine has a porous mucus layer, which permitted the uptake of MUC2 by antigen-sampling dendritic cells (DCs). Glycans associated with MUC2 imprinted DCs with anti-inflammatory properties by assembling a galectin-3-Dectin-1-FcγRIIB receptor complex that ...
Tópico(s): Immune Cell Function and Interaction
2013 - American Association for the Advancement of Science | Science
Produção Nacional
Revisado por pares
Maria Fernanda de Souza Costa, Catarina Bastos Trigo de Negreiros, Victor Ugarte Bornstein, Richard H. Valente, José Mengel, Maria das Graças Henriques, Cláudia F. Benjamim, Carmen Penido,
Lung inflammation is a major consequence of the systemic inflammatory response caused by severe sepsis. Increased migration of γδ T lymphocytes into the lungs has been previously demonstrated during experimental sepsis; however, the involvement of the γδ T cell subtype Vγ4 has not been previously described. Severe sepsis was induced by cecal ligation and puncture (CLP; 9 punctures, 21G needle) in male C57BL/6 mice. γδ and Vγ4 T lymphocyte depletion was performed by 3A10 and UC3-10A6 mAb i.p. administration, ...
Tópico(s): T-cell and B-cell Immunology
2015 - BioMed Central | BMC Immunology
Pedro P. Ugarte-Espinoza, Víctor Delgado-Soriano, Lorenzo Estivi, Alyssa Hidalgo, Gloria Pascual-Chagman,
In order to optimize the screw-press extraction conditions of oil from goldenberry (Physalis peruviana L.) seeds obtained from nectar processing waste, a face centered design was applied. The oil was extracted at different temperatures (60, 80, and 100°C) and seed moisture contents (8, 10, and 12%). Oil recovery (OR) increased and residual oil in the cake decreased significantly as moisture content and temperature were reduced; oil moisture and volatile matter as well as acid value, K232, K268, and ...
Tópico(s): Food Science and Nutritional Studies
2021 - Chiriotti Editori | Italian Journal of Food Science
Mar Cuadrado‐Tejedor, Carolina García, Juan A. Sánchez‐Arias, Obdulia Rabal, Marta Pérez-González, Sara Mederos, Ana Ugarte, Rafael Franco, Víctor Segura, Gertrudis Perea, Julen Oyarzábal, Ana García‐Osta,
The targeting of two independent but synergistic enzymatic activities, histone deacetylases (HDACs, class I and HDAC6) and phosphodiesterase 5 (PDE5), has recently been validated as a potentially novel therapeutic approach for Alzheimer's disease (AD). Here we report the discovery of a new first-in-class small-molecule (CM-414) that acts as a dual inhibitor of PDE5 and HDACs. We have used this compound as a chemical probe to validate this systems therapeutics strategy, where an increase in the activation ...
Tópico(s): Phosphodiesterase function and regulation
2016 - Springer Nature | Neuropsychopharmacology
Ana C. Gómez-Ugarte, Victor M. García-Guerrero,
Abstract The Mexican health system has been characterized by a mixture of progress and pitfalls, resulting in persistent inequalities. The main causes of death are related to socioeconomic factors reflecting the lack of opportunities regarding access to education, employment, income, and public health services. In this paper, we study the association between social inequality and mortality to assess how population composition by socioeconomic level shapes overall mortality. Socioeconomic information ...
Tópico(s): Insurance, Mortality, Demography, Risk Management
2023 - Springer Science+Business Media | Population Research and Policy Review
Manuel J. Cuesta, M. D. Ugarte, T. Goicoa, Sandra Eraso, Víctor Peralta,
Specific disorders within the psychosis syndrome have been proposed although no definitive validation of subtypes has been achieved. If there are subtypes of psychosis, latent discontinuity between clinical descriptors should be found. We applied for the first time taxometric analysis on characteristic schizophrenia symptoms. The sample consisted of 660 inpatients with an acute psychotic episode. Computed scores of the clinical dimensions included in the three-syndrome model of schizophrenia symptomatology ...
Tópico(s): Personality Disorders and Psychopathology
2007 - Elsevier BV | Psychiatry Research
Manuel F. Ugarte‐Gil, Víctor R. Pimentel-Quiroz, Luis M. Vilá, John D. Reveille, Gerald McGwin, Graciela S. Alarcón,
Objective The objective of this study was to determine the association of disease expression patterns with demographic and clinical characteristics in SLE. Methods Patients from a multi-ethnic SLE cohort were included. Disease expression patterns were defined as acute SLE and insidious SLE; this group was divided into those who accrued three ACR criteria and then accrued the fourth (insidious pattern A) and those who have one or two and then accrued four criteria (insidious pattern B). Disease activity ...
Tópico(s): T-cell and B-cell Immunology
2016 - SAGE Publishing | Lupus
... analizar las ideas de defensa continental que Manuel Ugarte y Víctor R. Haya de la Torre profesaron durante la ...
Tópico(s): History and International Relations
2011 - CIG Media Group | Latinoamérica Revista de Estudios Latinoamericanos
... por los intelectuales argentinos Ricardo Rojas y Manuel Ugarte, y los peruanos Victor Andres Belaunde y Jose Galvez durante sus visitas a Espana, y por el otro, se estudiaran aquellas misiones realizadas a comienzos del siglo XX por los espanoles Rafael Altamira y Adolfo Posada y por el argentino Manuel Ugarte en la America hispana, como parte de una ...
Tópico(s): Spanish Literature and Culture Studies
2000 - Complutense University of Madrid | Revista Complutense de Historia de América
Mar Cuadrado‐Tejedor, Carolina García, J. Sanzhez-Arias, Sara Mederos, Obdulia Rabal, Ana Ugarte, Rafael Franco, María Pascual‐Lucas, Víctor Segura, Gertrudis Perea, Julen Oyarzábal, Ana García‐Osta,
Given the implication of histone acetylation in memory processes, histone deacetylase inhibitors (HDACIs) have been postulated as potential modulators of cognitive impairment in Alzheimer's disease (AD). However, dose-dependent side effects have been described in patients with the currently available broad-spectrum HDACIs, explaining why their therapeutic potential has not been realized for chronic diseases. Here, by simultaneously targeting two independent enzyme activities, histone deacetylase (HDAC) ...
Tópico(s): Phosphodiesterase function and regulation
2015 - BioMed Central | Clinical Epigenetics
Rachel Atkinson, Evert Thomas, Federico Roscioli, Jonathan Cornelius, René Zamora‐Cristales, María Franco Chuaire, Carolina Alcázar, Francisco Mesén, Hariet Lopez, Roberto Ipinza, Pablo J. Donoso, Leonardo Gallo, Víctor Nieto, Julio Ugarte, Cuauhtémoc Sáenz‐Romero, Tobias Fremout, Riina Jalonen, H. Kindt Gaisberger, Barbara Vinceti, Michel Valette, E. Bosshard, Marius R. M. Ekué, Gabriela Wiederkehr Guerra, Chris J. Kettle,
Achieving multi-million-hectare commitments from countries around the world to restore degraded lands in resilient and sustainable ways requires, among other things, huge volumes of tree planting material. Seed systems encompassing all forest reproductive material (e.g., seeds, cuttings, stakes, and wildings), are key to ensuring that sufficient planting material with a diverse range of suitable species, adapted to local conditions and capable of persisting under a changing climate, is available ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2021 - Multidisciplinary Digital Publishing Institute | Diversity
David A. Potter, César A Herrera-Ponzanelli, Diego Hinojosa Ugarte, Rafael Castillo, Irwin A. Hernández-Cruz, Víctor A. Arrieta, Michael J. Franklin, Douglas Yee,
Neoadjuvant trials for early breast cancer have accelerated the identification of novel active agents, enabling streamlined conduct of registration trials with fewer subjects. Measurement of neoadjuvant drug effects has also enabled the identification of patients with high risk of distant recurrence and has justified development of additional adjuvant approaches to improve outcomes. Neoadjuvant evaluation of new drugs was significantly improved by the introduction of pathologic complete response ( ...
Tópico(s): Gene expression and cancer classification
2021 - | Faculty Reviews
A. Carrillo Álvarez, I. Ugarte, Víctor Fernández, Pablo Sánchez,
Heterogeneous architectures which integrate general purpose CPUs with specialized accelerators such as GPUs and FPGAs are becoming very popular since they achieve greater performance/energy trade-offs than CPU-only architectures. To support this trend, the OpenMP standard has introduced a set of offloading constructs that enable to execute code fragments in accelerator devices. The current offloading model heavily depends on the compiler supporting each target device, with many architectures still ...
Tópico(s): Advancements in Semiconductor Devices and Circuit Design
2019 - Springer Science+Business Media | Lecture notes in computer science
Miriam Partida-Pérez, María de la Luz Ayala-Madrigal, Jorge Peregrina-Sandoval, Nelly M. Macías-Gómez, José Miguel Moreno-Ortíz, Evelia Leal‐Ugarte, Mario A. Cárdenas-Meza, M. Centeno-Flores, Víctor Maciel-Gutiérrez, Enrique Cabrales, Sergio Cervantes-Ortiz, Melva Gutiérrez‐Angulo,
Leptin and adiponectin are cytokines produced by adipose tissue with opposite effects on tumor growth: the former stimulate whereas the latter inhibit it. The objective was to analyze the association of LEP A19G and ADIPOQ+45 T/G and +276 G/T polymor
Tópico(s): Adipose Tissue and Metabolism
2011 - IOS Press | Cancer Biomarkers
Walter David Ugarte Casafranca, Víctor Félix Portocarrero Chávez,
El Distrito de Mollepata está ubicado en la Provincia de Anta de la Región Cusco, Perú. A partir de los esfuerzos por la puesta en valor de las ruinas de Choquequirao, considerada como la “hermana sagrada de Machu Picchu” y del complejo arqueológico de Quillarumiyoc, se han desarrollado programas de incentivo del turismo alternativo en su modalidad de turismo vivencial. En esta localidad podemos encontrar, además recursos culturales notables como las festividades del Señor Manuel de la Santa Cruz ...
Tópico(s): Business, Innovation, and Economy
2013 - | Gestión en el Tercer Milenio
Manuel F. Ugarte‐Gil, Rocío V. Gamboa‐Cárdenas, Cristina Reátegui-Sokolova, Víctor R. Pimentel-Quiroz, Mariela Medina, Claudia Elera‐Fitzcarrald, Francisco Zevallos, Cesar Augusto Pastor-Asurza, J. H. Lofland, F. Zazzetti, Chetan S. Karyekar, Graciela S. Alarcón, Risto Perich-Campos,
To determine if achieving lupus low disease activity state (LLDAS) or remission prevents damage accrual in a primarily Mestizo population.
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2022 - BMJ | Lupus Science & Medicine
Francisco Arriagada, Catalina Ugarte, Germán Günther, María Angélica Larraín, Víctor Guarnizo-Herrero, Santi Nonell, Javier Morales,
The incorporation of pigments and natural polyphenols into inorganic matrices, resulting in a hybrid material that improves the resistance and chemical stability of the pigments and the antioxidant capacity of the materials, has been of great interest to the pharmaceutical, chemical and food industries. The aim of this work was to prepare and characterize a bifunctional pigment-antioxidant nanomaterial-based carminic acid-decorated solid core-mesoporous shell silica nanoparticles, evaluating its ...
Tópico(s): Olfactory and Sensory Function Studies
2020 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Peter Podgorny, Laura M. Pratt, Yiping Liu, Poonam Dharmani‐Khan, Joanne Luider, Iwona Auer-Grzesiak, Adnan Mansoor, Tyler Williamson, Alejandra Ugarte-Torres, Mette Hoegh-Petersen, Faisal Khan, Loree Larratt, Víctor H. Jiménez‐Zepeda, Douglas A. Stewart, James A. Russell, Andrew Daly, Jan Storek,
Hematopoietic cell transplant (HCT) recipients are immunocompromised and thus predisposed to infections. We set out to determine the deficiency of which immune cell subset(s) may predispose to postengraftment infections. We determined day 28, 56, 84, and 180 blood counts of multiple immune cell subsets in 219 allogeneic transplant recipients conditioned with busulfan, fludarabine, and Thymoglobulin. Deficiency of a subset was considered to be associated with infections if the low subset count was ...
Tópico(s): Reproductive System and Pregnancy
2015 - Elsevier BV | Biology of Blood and Marrow Transplantation
... 3-030-48616-7_28-1Takayuki Nishimura, Juan Ugarte, Mayumi Ohnishi, Mika Nishihara, Guillermo Alvarez, Yoshiki Yasukochi, Hideki Fukuda, Kazuhiko Arima, Shigeki Watanuki, Victor Mendoza, Kiyoshi Aoyagi Individual variations and sex differences ...
Tópico(s): Environmental and Cultural Studies in Latin America and Beyond
1989 - University of Chicago Press | Isis
Marisa Fernández, Víctor Manero, Antonio Otal, Luis Ugarte,
We classify solvable Lie groups admitting left invariant symplectic half-flat structure. When the Lie group has a compact quotient by a lattice, we show that these structures provide solutions of supersymmetric equations of type IIA.
Tópico(s): Geometric Analysis and Curvature Flows
2012 - Springer Science+Business Media | Annals of Global Analysis and Geometry
Víctor R. Pimentel-Quiroz, Manuel F. Ugarte‐Gil, Graciela S. Alarcón,
Introduction: Due to improvements in our understanding of the pathogenesis of systemic lupus erythematosus (SLE), several target drugs have been and are being developed. One of the possible targets in SLE is co-stimulation between antigen-presenting cells and T cells. Abatacept is a co-stimulation moderator approved for the treatment of several autoimmune diseases. There is an unmet need for drugs with a better efficacy and safety profile when treating patients with SLE.Areas covered: In this review, ...
Tópico(s): T-cell and B-cell Immunology
2016 - Taylor & Francis | Expert Opinion on Investigational Drugs
Produção Nacional
Revisado por pares
Víctor R. Pimentel-Quiroz, Manuel F. Ugarte‐Gil, G. moore Harvey, Daniel Wojdyla, Guillermo J. Pons‐Estel, Rosana Quintana, Amadeo Esposto, Mercedes García, Luís J. Catoggio, Mario H. Cardiel, Leonor Barile, Mary‐Carmen Amigo, Emília Inoue Sato, Eloísa Bonfá, Eduardo Ferreira Borba, Lílian Tereza Lavras Costallat, Óscar Neira, Loreto Massardo, Marlene Guibert-Toledano, R. Chacón, Graciela S. Alarcón, Bernardo A. Pons‐Estel,
Aim The aim of this study was to identify factors predictive of serious infections over time in patients with systemic lupus erythematosus (SLE). Methods A multi-ethnic, multi-national Latin American SLE cohort was studied. Serious infection was defined as one that required hospitalization, occurred during a hospitalization or led to death. Potential predictors included were sociodemographic factors, clinical manifestations (per organ involved, lymphopenia and leukopenia, independently) and previous ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2019 - SAGE Publishing | Lupus
Produção Nacional
Revisado por pares
Jorge I. Salluh, Márcio Soares, José Teles, Daniel Ceraso, N. Raimondi, Victor S Nava, Patrícia Blasquez, Sebastián Ugarte, C. Ibáñez-Guzmán, J. Vergara Centeno, Manuel Laca, Gustavo Grecco, Edgar Jiménez, S. Arias-Rivera, Carmelo Dueñas Castell, Marcelo Rocha,
Abstract Introduction Delirium is a frequent source of morbidity in intensive care units (ICUs). Most data on its epidemiology is from single-center studies. Our aim was to conduct a multicenter study to evaluate the epidemiology of delirium in the ICU. Methods A 1-day point-prevalence study was undertaken in 104 ICUs from 11 countries in South and North America and Spain. Results In total, 975 patients were screened, and 497 fulfilled inclusion criteria and were enrolled (median age, 62 years; 52. ...
Tópico(s): Anesthesia and Sedative Agents
2010 - BioMed Central | Critical Care
Produção Nacional
Revisado por pares
Víctor R. Pimentel-Quiroz, Manuel F. Ugarte‐Gil, Guillermo J. Pons‐Estel, Enrique R. Soriano, Verónica Saurit, Emília Inoue Sato, Lílian Tereza Lavras Costallat, José Fernando Molina, Antonio Iglesias Gamarra, Gil Reyes-Llerena, Óscar Neira, Leonor Barile, Luis H. Silveira, María I Segami, R. Chacón, Daniel Wojdyla, Graciela S. Alarcón, Bernardo A. Pons‐Estel,
To determine the factors predictive of disease activity early in the course of SLE (baseline visit).Patients from GLADEL, a multi-national, multi-ethnic, Latin-American lupus cohort were included. Disease activity was evaluated at baseline with the SLEDAI score. Demographic characteristics (age at diagnosis, gender, ethnicity, marital status, educational level, medical coverage and socioeconomic status) were assessed. Disease duration was defined as the time between the fourth ACR criterion and baseline. ...
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2017 - Elsevier BV | Seminars in Arthritis and Rheumatism
Yoshiki Yasukochi, Takayuki Nishimura, Juan Ugarte, Mayumi Ohnishi, Mika Nishihara, Guillermo Álvarez, Hideki Fukuda, Victor Mendoza, Kiyoshi Aoyagi,
The physiological characteristics of Andean natives living at high altitudes have been investigated extensively, with many studies reporting that Andean highlanders have a higher hemoglobin (Hb) concentration than other highlander populations. It has previously been reported that positive natural selection has acted independently on the egl-9 family hypoxia inducible factor 1 (EGLN1) gene in Tibetan and Andean highlanders and is related to Hb concentration in Tibetans. However, no study has yet revealed ...
Tópico(s): Hemoglobinopathies and Related Disorders
2020 - Hindawi Publishing Corporation | BioMed Research International
Manuel F. Ugarte‐Gil, Rocío V. Gamboa‐Cárdenas, Cristina Reátegui-Sokolova, Víctor R. Pimentel-Quiroz, Mariela Medina, Claudia Elera‐Fitzcarrald, Francisco Zevallos, Cesar Augusto Pastor-Asurza, F. Zazzetti, Chetan S. Karyekar, Graciela S. Alarcón, Risto Perich-Campos,
Background Flares in patients with SLE, regardless of their severity, have been associated with damage accrual. However, their impact on health-related quality of life (HRQoL) has not been fully evaluated. In fact, disease activity is only minimally associated with HRQoL. Objective To determine the association between flares and HRQoL. Methods Patients from the Almenara Lupus Cohort were included. Visits occurring between December 2015 and February 2020 were evaluated. Flares were defined as an increase ...
Tópico(s): Immune Cell Function and Interaction
2022 - BMJ | Lupus Science & Medicine
Víctor Pacheco, Joaquín A. Ugarte-Núñez,
Tópico(s): Bat Biology and Ecology Studies
2011 - Springer Science+Business Media | Mammalian Biology