Geoff Boycott, Audrey Slaughter, Jerzy Kosinski, Rosemary Righter, Rio de Janeiro, Paul Theroux, Victoria Glendinning, Roger Eglin Industrial Editor, John Fryer, Nicholas Carroll Diplomatic Correspondent, Jon Swain, Chris Ryder, Heidi Holland, Peter Calvocoressi, Berry Ritchie, Graham Rose, Antony Terry, John Whale Religious Affairs Editor, Prince Marshall, Michael Binyon, Philip, John Whale, Nick Pitt, Cyril Hartley, Douglas McVay, Ian fack, Ludovic Kennedy, Peter Levi, Alison Levy, Bob Campbell, Colin Simpson, Brian McLean, Henry Brandon, Peter Rodgers, Richard Milner, Bernard Levin, Keith Botsford, Cattani, David Dougill, John Mortimer, Joe Irving, David Jenkins, Mrs Trudy Watson, Cliff Temple, Robert Eastaway, Martin Vessey, Sasthi Brata, Howard Dove Director, Peter Rodgers Energy Editor, John Ballantine, Norman Harris, David Blundy, Michael Jones, Geoffrey Cannon, Peter Kellner, George Perry, Larry Rohter, John Sheppard, Patrick Forman, Roger Eglin, Mrs Diana M. P. Harris, Michael Bilton, Andrew Cornelius, Michael Nimmo, Frank Giles Deputy Editor of The Sunday Times, Lorana Sullivan, Ann George Housewife, B. P. White, Jeremy Lovell, Nick King, Tony Geraghty, Toni Turner, Brian Jackman, Judith Jackson, Richard Girling, Byran Silcock, John Fryer Labour Correspondent, Nick Gilbert, John Hopkins, J C Brown, Alex Raymond, Denis Herbstein, C. C. Pearson The Arab Horse Society, Eric Marsden, Stephen Wood, Jill Tweedle, Hugo Young Political Editor, Stephen Pile, Gareth Huw Davies, Patricia Connor, Malcolm Winton, Denis Reinhardt, Peter Stothard, David May, Desmond Shawe-Taylor, Alan Brien, Russell Davies, Jim Reynolds, Betka Zamovska, Jean Robertson, Jude Garvey, John Bell City Editor, Jean Hudson Housewife, Brough Scott, Deyan Sudjic, Oliver Gillie Medical Correspondent, Tony Osman, Nick Baldwin, Barrie Penrose, Dudley Doust, Felix Aprahamian, Alison Miller, Franklin Mint, John Wilcockson, John O'neill, John H Gibbs, Harald Offerdahl, J W Lambert, Mary Davis Peters, Dr D K Sen Gupta, Peter Clarke, Christopher Ricks, Hunter Davies, John Carey, Andrew Lycett, Graham Searjeant, Johannesburg, Peter Dunn, Michael Roberts, James Fenton, Will Elsworth-Jones, Michael Jones Political Correspondent, William S Batchford, Michael Parkinson, James Woods, Lincoln Cathedral, Marina Vaizey, Denis Howell, Dr E Kibblewhite, Malcolm Crawford, Roger Rateliffe, Pauline Peters, Patience Wheatcroft, Joan Smith, Boris Schapiro,
... Multiple Classified Advertising Items Telford Carphone Consultants Envirogarde VAP International Communications Multiple Classified Advertising Items Hastings Borough ...
1980 - Gale Group | Sunday Times HA GDA
Mevlüt Karataş, Sedat Saylan, Uğur Kostakoğlu, Gürdal Yılmaz,
Ventilator-associated pneumonia (VAP) is a significant cause of hospital-related infections, one that must be prevented due to its high morbidity and ... the incidence and risk factors in patients developing VAP in our intensive care units (ICUs).This retrospective ... ventilated patients hospitalized for more than 48 hours. VAP diagnosed patients were divided into two groups, those developing pneumonia (VAP(+)) and those not (VAP(-)).\.We researched 1560 patients in adult ICUs, 1152 ( ... mechanically ventilated. The MV use rate was 52%. VAP developed in 15.4% of patients. The VAP ...
Tópico(s): Inhalation and Respiratory Drug Delivery
1969 - Professional Medical Publications | Pakistan Journal of Medical Sciences
Violet Brand, Mark Skipworth Consumer Affairs Correspondent, Kenneth McLeish, Barbara Hall, Jenny Rainbird, Adrian Room, Mike Graham, E P Maienry, Paul Nelson, Michelene Wandor, Michael Saward, John Davison, John Bakewell, M Niemojowska, Alexandra Frean, Anthony Clare, John Peter, Andrew Grice Political Correspondent, Mark Reason, Eric Dymock, Norman MacRae, John Batchin, Fiona Walsh, Danby Bloch, Alan Judd, Graham Rose, Philippa Pigache, Norman Howell, Andrew Robinson, Diana Wright Personal Finance Editor, Robert Burchfield, David Smith, Steve Clarke, Ben Brantley, Bob Holmes, John Rowland, Edward Welsh, Tony Walsh, Susan Irvine, Rita Kayes, Geordie Greig, Tony Allen-Mills, Patrick Stoddart, Robert Sandall, Iain Johnstone, Susan d'ARCY, Mikhali Gorbachav, Topper Weekly, Irwin Stelzer, Victor Trestnlkov, Ivan Fallon, Deryk Brown, Professor Malcolm Bradbury, Alan Bergson, Frances Walte, Madge Goodall, Beryl Bainbridge, Steve Clarke Media Correspondent, Andrew Naham, Hugh Canning, Margarette Driscoll, Colin Dryden, Jane Bird Technology Editor, Susan Crosland, David Cairns, Peter Kemp, David Goldsmith, John Kerridge, John McGahern, Ibrahim Ahmed al-Nouri, Jon Wynne-Tyson, James Pye, Barry Chapman, George Perry, Robin Marlar, Paul Golding, Bernard Cafferty, Stuart Wavell, Paul Donovan, Dr Maggie Curley, Janette Marshall, Roslyn Grose, Jilly Cooper, Jeff Randall, Paul Driver, James Adams, David Hughes, Mary Elliott, Tim Rayment, Peter Plant, Huge Duckert, Tom Shone, Tim Chamberlin, Rufus Olins, Ayatollah Ali Khamenei, Anne Williams, Derek Jameson, John Hopkins, Stephen Wood, Lola Smith, Gareth David, Leonard Cheshire, Penelope Fitzgerald, John Karter, Kate Saunders, Malcolm Winton, Raleigh Trevelyan, Richard Cook, Malcolm Flatt, Craig Brown, Diana Wright, Andrew Lorenz Industrial Editor, Jay Leno, Stephen Jones, Stephen Thorpe, Robert Hanslip, Digby Anderson, Martin Searby, Keith Wheatley, Miranda Seymour, Keith Martin, Patrick Rowley, Dilys Powell, Hugh Johnson, Bryan Appleyard, Peter Plani, Chris Jones, Tim Willis, Andrew Hogg, Bruce Johnston, Roger Putnam, David Moxey, Norman Stone, Richard Woods, Anwer Bati, Barbara Maxwell, Marion Hume, Ian Dunning, John Walsh, Ruby Millington, David Hughes Chief Political Correspondent, Wing Cdr Derek Martin, Brian MacArthur, A S Byatt Chatto, Brian Moore, Michael Jones Political Editor, Harold J Green, James Blitz, Kenichi Ohmae, Naomi Wolf, Christopher Hawtree, D J Taylor, Stuart Weir, Mihir Bose, Angela Neustatter, Godfrey Smith, W Smith, Michael Austin, Rachel Charles, Judith Earashaw, Andrew Alderson, rabid foxes, Paul Barker, Sam Klley, Daniel Ward, Brian Glanville, Stan Levenson, Guy Collings, Chris Dighton, Godfrey Golzen, Mordecai Richler, Peter, Gareth David Deputy City Editor, Andrew Lorenz, Piergiorgio Mordasini, John Furbisher, Nigel Kennedy, David Wickers, John Parker, Jonathan Futrell, Marina Vaizey, Chris Lightbown, Jeff Randall City Editor, P Holmes, Lord Young, Hugh Pearman, Margaret Park, Angela Long, Phillip Knightley, Frank Field, Neil Lyndon Main, David Smith Economics Editor, Penny Perrick, Tony Hetherington, Anthony Howard, G Lewis, Peter Roebuck, James Adams Defence Correspondent, Michael Kenward, Boris Schapiro,
... Berry Wilson Associates Ltd Greenfield International Wool Sechetrait VAP Recruitment Peak Consulting Services Royal Academy of Arts ...
1990 - Gale Group | Sunday Times HA GDA
Canan Bor, Kubilay Demırağ, Özlem Okcu, İlkin Çankayalı, Mehmet Uyar,
Objective: Ventilator-associated pneumonia (VAP) is an infection with high mortality and morbidity that prolongs the length of stay in the intensive care unit (ICU) and hospitalisation. VAP is one of the most common infections in ... patients. This study aimed to prospectively determine the VAP rate and associated factors in critically ill patients ... 2010-2011) were included for follow-up for VAP diagnosis. Demographic data, APACHE II scores, diagnoses on ... CRP, procalcitonin, risk factors for infection, time to VAP diagnosis, and bacteriological culture results were recorded. All ...
Tópico(s): Intensive Care Unit Cognitive Disorders
1969 - Professional Medical Publications | Pakistan Journal of Medical Sciences
G. T. Pearce, Widget Finn, Ivor H. Mills, Edward Gorman Irish Affairs Correspondent, Frances Gibb, Legal Affairs Correspondent, Colin Bewick, Victoria Glendinning, Douglas Broom and Paul Wilkinson, Frank Nickels, Michael Clewett, Sheridan Morley, Ivo Tennant, Matt Wolf, Michael Seely, Racing Correspondent, John Bell, City Editor, Isabel Raphael, Jeremy Kingston, Philip Webster and James Bone, Lance I. Sanders, Carol Leonard, Louis Taylor, Leila Jaroudi, Peter Aldhous, Harry Eyres, Richard Streeton, Richard Eaton, David Ogden, Simon Wilde, Stuart Jones Football Correspondent, Stewart Tendler, Crime Correspondent, Geoff Brown, James Tye, Director General, Martin Fletcher, Henry Gee, Michael Dockrill, Nick Stewart, Bruce Clark, Michael Soltys, Norman Hammond, Archaeology Correspondent, Peter Ball, James H. H. Merriman, Raymond Keene Chess Correspondent, Richard Ford Political Correspondent, Shaun Johnson, Matthew May, Nick Nuttall Technology Correspondent, D. R. Jarman, Headmaster, Robin Young, N. C. F. Barber, John Winder, Stephen Byrne, Nicholas Baker, Douglas Broom, Local Government Correspondent, J. V. Gower, Colin Narbrough and John Durie, Neil Bennett Banking Correspondent, Ian Knight, Leslie Tilley, Harvey Elliott, Air Correspondent, Philip Webster and Craig Seton, Gavin Bell, John Woodcock, Michael Theodoulou, Kevin S. Parrott, Dennis Signy, Grange Turner, David Miller, Robin Oakley Political Editor, Gillian Bowditch, Mitchell Platts Golf Correspondent, Geoffrey Wheeler, Christopher Goulding, Andrew McEwen, Diplomatic Editor, Robin Oakley, Political Editor, Catherine Sampson, Kerry Gill, Jonathan Prynn, David Robinson, Alan Lee, Cricket Correspondent, Raymond Keene, Chess Correspondent, Paul Wilkinson, Chris Partridge, Liz Gill, Richard Evans, Nigel Hawkes, George Bickerstaffe, Craig Seton, Barry Pickthall, Peter Guilford, Marcel Berlins, Roger Boyes, Geoff Cox, Wolfgang Munchau and George Sivell, John O'leary, Higher Education Correspondent, Derek Harris, Industrial Editor, David Hands Rugby Correspondent, Michael Hare, Christopher Thomas, John Goodbody, Andrew Sinclair, Christopher Walker, Yousuf A. Shirawi, George Hill, Alan Tillier, Peter Stothard, us Editor, Clive White, Matthew Parris, Graham Searjeant Financial Editor, David Brewearton, Ms Louise Bagshawe, Tom McEWAN, Andrew C. N. Walker, Humphrey Clucas, Thomson Prentice, Medical Correspondent, Peter Victor, Michael Knipe, Diplomatic Correspondent, Philip Webster, Stuart Milner-Barry, Peter Mulligan, Benedict Nightingale, Quentin Cowdry, Home Affairs Correspondent, Dr Thomas Stuttaford, Michael Tate Deputy City Editor, Anne McElvoy, Michael Evans, Matthew Bond, Colin Campbell, Susan Ellicott, Mike Rosewell, Rowing Correspondent, Clement Freud,
... Sales & Marketing Appointments Director of Marketing Greenfield IWS VAP Peak Royal Academy of Arts Project Leader Connaught ...
1990 - Gale Group | TDA
Agop Y. Bedikian, Yehuda Z. Patt, William K. Murphy, Theera Umsawasadi, David Carr, Evan M. Hersh, Gerald P. Bodey, Manuel Valdivieso,
... remission induction chemotherapy with vindesine, doxorubicin, and cisplatin (VAP). Fifty-four patients received VAP alone. Fifty-one patients received VAP + thymosin. Both groups were comparable; most patients were ... 22 PRs) of 53 (45%) patients treated with VAP and 10 (all PRs) of 46 (22%) patients treated with VAP + thymosin (p = 0.03). VAP-treated patients responded better than those treated with VAP + thymosin in each tumor category: adenocarcinoma, 50% of ... weeks versus 25 weeks in favor of the VAP-treated group (p = 0.14). Thymosin treatment resulted ...
Tópico(s): Lung Cancer Research Studies
1984 - Lippincott Williams & Wilkins | American Journal of Clinical Oncology
Soumitra R. Eachempati, Lynn J. Hydo, Jian Shou, Philip S. Barie,
Background: Ventilator-associated pneumonia (VAP) is a leading cause of mortality in critically ill patients. Although previous studies have shown that de-escalation therapy (DT) ... with septic shock. We hypothesized that DT for VAP was not associated with an increased rate of ... patients from January 2005 to May 2007 with VAP diagnosed by quantitative bronchoalveolar lavage with a positive ... of antibiotic therapy based on microbiology for their VAP. Results: One hundred thirty-eight of 1,596 SICU patients developed VAP during the study period (8.7%). For VAP ...
Tópico(s): Intensive Care Unit Cognitive Disorders
2009 - Lippincott Williams & Wilkins | Journal of Trauma and Acute Care Surgery
Hung‐Yuan Li, Jung-Nan Wei, Mao-Shin Lin, David J. Smith, Jani Vainio, Cheng-Hsin Lin, Fu‐Tien Chiang, Shyang‐Rong Shih, Ching-Huei Huang, Mei-Yu Wu, Yenh-Chen Hsein, Lee‐Ming Chuang,
The relationship between serum vascular adhesion protein-1 (VAP-1) and plasma glucose in normal and drug- ... diabetes subjects is unclear. We examined if serum VAP-1 changed acutely to oral glucose loading and analyzed the relationship between serum VAP-1, fasting plasma glucose (FPG), hemoglobin A1c, and ... Subjects taking anti-diabetic drugs were excluded. Serum VAP-1 was analyzed by time-resolved immunofluorometric assay. ... 1 ± 11.6 y. After glucose challenge, serum VAP-1 rose significantly at 30 min (p < 0. ...
Tópico(s): Lipid metabolism and disorders
2009 - Elsevier BV | Clinica Chimica Acta
Bekele Afessa, Andrew F. Shorr, Antonio Anzueto, Donald E. Craven, Regina Schinner, Marin H. Kollef,
... ETT) reduced the incidence of ventilator-associated pneumonia (VAP) compared with an uncoated ETT in the North ... a retrospective cohort analysis in patients who developed VAP in the NASCENT study. We determined causes of death and VAP due to potentially multidrug-resistant bacteria (eg, Pseudomonas, ... was associated with reduced mortality in patients with VAP (silver vs control, 5/37 [14%] vs 20/ ... 36%], P = .03), but not in those without VAP (228/729 [31%] vs 178/687 [26%], P = . ... vs 22/198 [11%], P = .02). Of the VAP-related deaths, one in the silver group was ...
Tópico(s): Healthcare Decision-Making and Restraints
2009 - Elsevier BV | CHEST Journal
Margo A. Halm, Rochelle Armola,
... create a code to identify ventilator-associated pneumonia (VAP) as a future preventable hospital-acquired condition.2 ... cuff has proven effective in reducing rates of VAP.11–14 Although many believe that oral care ... exists on the impact of such regimens on VAP. In this review, we summarize the current evidence ... using the key words oral care, bacterial colonization, VAP, and critically ill patients. Only randomized controlled trials ... of most studies indicated that chlorhexidine interventions reduced VAP rates.7,15,16,18 Hazard ratios ranged ...
Tópico(s): Respiratory and Cough-Related Research
2009 - American Association of Critical-Care Nurses | American Journal of Critical Care
The development of ventilator-associated pneumonia (VAP) requires microbial pathogens to gain access to the lower respiratory tract. The GI and upper respiratory tract are thought to represent the ... pathogenic organisms represents a potential target for preventing VAP. A variety of strategies for decontamination of the ... concluded that SDD significantly reduces the incidence of VAP. It may even reduce mortality in certain populations ... Scholar demonstrated no decrease in the rate of VAP in patients treated with iseganan when compared to ...
Tópico(s): Pneumonia and Respiratory Infections
2009 - Elsevier BV | CHEST Journal
... and consumer advocates to drive ventilator-associated pneumonia (VAP) rates to zero, the article by Conway Morris ... issue of Thorax is a timely reminder that VAP rates are uncertain estimates rather than concrete measures ... Conway Morris and colleagues show that the reported VAP rate of an Intensive Care Unit (ICU) is ... that exclusively use bronchoalveolar lavage (BAL) to diagnose VAP are liable to report VAP rates that are 76% lower than those that exclusively use endotracheal aspirates. This laxity in the VAP definition confers a risk that some well-intended ...
Tópico(s): Intensive Care Unit Cognitive Disorders
2009 - BMJ | Thorax
Charity Wip, Lena M. Napolitano,
... of care bundles to prevent ventilator-associated pneumonia (VAP). Recent findings The Ventilator Bundle contains four components, ... ventilated patients, but not all are associated with VAP prevention. Daily spontaneous awakening and breathing trials are associated with early liberation from mechanical ventilation and VAP reduction. Although a small prospective, randomized clinical study ... position was associated with a significant reduction in VAP, more recent studies have documented that the semirecumbent ...
Tópico(s): Pneumonia and Respiratory Infections
2009 - Lippincott Williams & Wilkins | Current Opinion in Infectious Diseases
... The proposal that reimbursement for ventilator-associated pneumonia (VAP) would be one of the next “preventable complications” ... of uncertainty in making the diagnosis and because VAP is likely not entirely preventable. However, this disagreement has refocused interest in strategies for preventing VAP and decreasing associated morbidity, mortality, and health-care ... can decrease the number of subsequent diagnoses of VAP, improve the duration of mechanical ventilation, and even ... respiratory tract colonization with potentially pathogenic microorganisms and VAP. It is theorized that antibiotic treatment of VAT ...
Tópico(s): Healthcare Decision-Making and Restraints
2009 - Elsevier BV | CHEST Journal
Victor M. Zaydfudim, Lesly A. Dossett, John M. Starmer, Patrick G. Arbogast, Irene D. Feurer, Wayne A. Ray, Addison K. May, C. Wright Pinson,
Ventilator-associated pneumonia (VAP) causes significant morbidity and mortality in critically ill surgical patients. Recent studies suggest that the success of preventive measures ... with the bundle parameters and reduce rates of VAP in our surgical intensive care unit (SICU).Time series analysis of VAP rates between January 2005 and July 2008, with ... control data were used to establish rates of VAP and total ventilator days. For the time series analysis, VAP rates were calculated as quarterly VAP events per ...
Tópico(s): Emergency and Acute Care Studies
2009 - American Medical Association | Archives of Surgery
Sandy Bour, Sylvie Caspar‐Bauguil, Zsuzsa Iffiú-Soltész, Maryse Nibbelink, Béatrice Cousin, Mari Miiluniemi, Marko Salmi, Craig Stolen, Sirpa Jalkanen, Louis Casteilla, Luc Pénicaud, Philippe Valet, Christian Carpéné,
... also known as vascular adhesion protein-1 (SSAO/VAP-1), is a membrane protein that is highly ... oxidase copper-containing-3 (AOC3) gene encoding SSAO/VAP-1. Both epididymal and inguinal WATs were larger ... KO mice was not rescued by human SSAO/VAP-1 expression on adipocytes under the control of ... entrance into fat. Our results indicate that SSAO/VAP-1 is instrumental for the presence of leukocytes ... also known as vascular adhesion protein-1 (SSAO/VAP-1), is a membrane protein that is highly ... oxidase copper-containing-3 (AOC3) gene encoding SSAO/VAP-1. Both epididymal and inguinal WATs were larger ...
Tópico(s): Body Contouring and Surgery
2009 - Elsevier BV | American Journal Of Pathology
Ángel Pobo, Thiago Lisboa, Alejandro Rodríguez, Ramiro Sole, Mònica Magret, Sandra Trefler, Frederic Gómez, Jordi Rello,
... care in order to reduce ventilator-associated pneumonia (VAP) incidence is unknown. Methods The study design was ... standard oral care plus electric toothbrushing (toothbrush group). VAP was documented by quantitative respiratory cultures. Mechanical ventilation ( ... and standard group had similar rates of suspected VAP (20.3% vs 24.7%; p = 0.55). ... and admission diagnosis, the incidence of microbiologically documented VAP was also similar in the two groups (hazard ... digluconate is not effective for the prevention of VAP. Trial registration ClinicalTrials.gov Identifier: NCT00842478 Poor oral ...
Tópico(s): Airway Management and Intubation Techniques
2009 - Elsevier BV | CHEST Journal
Brenda Morrow, Andrew C. Argent,
... South African paediatric patients with ventilator-associated pneumonia (VAP).Non-bronchoscopic bronchoalveolar lavage (BAL) specimens taken between ... recorded and related clinical data were retrospectively reviewed. VAP was defined as a new isolate on BAL ... after intubation, 63 specimens from 55 patients fulfilled VAP criteria. Acinetobacter baumannii was the most common VAP pathogen, followed by Klebsiella pneumoniae, viruses, yeasts and Staphylococcus aureus. Patients who developed VAP had a higher proportion of comorbid conditions (76% ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2009 - Wiley | Journal of Paediatrics and Child Health
S. Andrew Josephson, Asma Moheet, Michael A. Gropper, Amy Nichols, Wade S. Smith,
Ventilator-associated pneumonia (VAP) is the most common nosocomial infection among medical intensive care unit (ICU) patients and is associated with increased mortality ... LOS). Neurologic disease is a risk factor for VAP development, but the relationship between VAP and outcomes in patients admitted to the ICU ... neurologic patients who did and did not develop VAP were made using univariate and multivariate analysis.Of 585 intubated neurovascular patients, 24 (4.1%) developed VAP. Compared with those who did not develop VAP, ...
Tópico(s): Respiratory Support and Mechanisms
2009 - Springer Science+Business Media | Neurocritical Care
L. Almulki, Kousuke Noda, Shintaro Nakao, Toshio Hisatomi, Kennard L. Thomas, Ali Hafezi‐Moghadam,
... a critical role for Vascular Adhesion Protein-1 (VAP-1) in rodents during acute ocular inflammation, angiogenesis, and diabetic retinal leukostasis. However, the expression of VAP-1 in the human eye is unknown. VAP-1 localization was therefore investigated by immunohistochemistry. Five ... Sections were incubated overnight with primary mAbs against VAP-1 (5 μg/ml), smooth muscle actin (1 ... 4 discrete categories. In all examined ocular tissues, VAP-1 staining was confined to the vasculature. VAP-1 labeling showed the highest intensity in both ...
Tópico(s): Renal Diseases and Glomerulopathies
2009 - Elsevier BV | Experimental Eye Research
Arnaud Gacouin, Nicolas Barbarot, Christophe Camus, Sylvain Salomon, Sonia Isslame, Sophie Marqué, Sylvain Lavoué, Pierre-Yves Donnio, R. Thomas, Yves Le Tulzo,
... the acquisition of late-onset ventilator-associated pneumonia (VAP) were performed in critically ill trauma patients. The ... enteral nutrition (EN) on the risk of acquiring VAP has been discussed. In this study, we assessed factors associated with late-onset VAP in nontrauma patients and determined whether nutrition provided early was associated with development of late-onset VAP in this population.We performed a prospective observational ... admitted over a 28-mo period. Late-onset VAP was confirmed in 76 patients (21%) by the ...
Tópico(s): Intensive Care Unit Cognitive Disorders
2009 - Lippincott Williams & Wilkins | Anesthesia & Analgesia
J. Perren Cobb, Ernest E. Moore, Doug Hayden, Joseph P. Minei, Joseph Cuschieri, Jingyun Yang, Qing Li, Nan Lin, Bernard H. Brownstein, Laura Hennessy, Philip H. Mason, William Schierding, David Dixon, Ronald G. Tompkins, H. Shaw Warren, David Schoenfeld, Ronald V. Maier,
... pilot microarray study of 11 ventilator-associated pneumonia (VAP) patients suggested that 85 leukocyte genes can be used to diagnose VAP. Validation of this gene set to detect VAP was tested using data from an independent patient ... enrolled at 5 centers, where 57 (36%) developed VAP. Patient age was 34.2 ± 11.1 years; ... patients was tested to determine predictive accuracy for VAP 4 days prior to clinical diagnosis in the ... 85 genes were associated with the diagnosis of VAP 1 to 4 days before diagnosis. However, the ...
Tópico(s): Sepsis Diagnosis and Treatment
2009 - Lippincott Williams & Wilkins | Annals of Surgery
Allan J. Walkey, Christine C. Reardon, Carol Sulis, R. Nicholas Nace, Martin Joyce‐Brady,
... the epidemiology and microbiology of ventilator-associated pneumonia (VAP) in a long-term acute care hospital (LTACH).Retrospective study of prospectively identified cases of VAP.Single-center, 207-bed LTACH with the capacity ... January 31, 2008.Data on the occurrence of VAP were collected prospectively as part of routine infection ... a bundle of interventions for the prevention of VAP (hereafter referred to as the VAP-bundle approach). A case of VAP was defined as a patient who required mechanical ... Centers for Disease Control and Prevention criteria for VAP. Sputum samples were collected from a tracheal aspirate ...
Tópico(s): Healthcare Decision-Making and Restraints
2009 - Cambridge University Press | Infection Control and Hospital Epidemiology
Paula Ramírez, Miquel Ferrer, R. Gimeno, Sergi Tormo, Mauricio Valencia, R. Piñer, Rosario Menéndez, Antoní Torres,
... diagnosis and follow-up of ventilator-associated pneumonia (VAP), but their potential role in predicting the risk for VAP is unknown. We prospectively assessed the evolution of ... patients and their predictive and diagnostic role for VAP. Design: Prospective observational study. Setting: Medical intensive care ... factor-alpha were done in 44 ventilated patients. VAP was suspected in 20 cases and microbiologically confirmed ... values did not discriminate patients with and without VAP, but the median (interquartile range) serum levels of ...
Tópico(s): Sepsis Diagnosis and Treatment
2009 - Lippincott Williams & Wilkins | Critical Care Medicine
Breena R. Taira, Kimberly Fenton, Thomas K. Lee, Hongdao Meng, Jane E. McCormack, Emily Huang, Adam J. Singer, Richard J. Scriven, Marc J. Shapiro,
Ventilator-associated pneumonia (VAP) is a significant cause of secondary morbidity and mortality in adult trauma patients. No study has characterized VAP in pediatric trauma patients. We determined the rates of and potential risk factors for VAP in pediatric trauma patients.A countywide trauma registry identified all pediatric trauma patients with potential VAP treated at a Regional Trauma Center. After a ... poisonings were excluded. The registry identified 14 potential VAPs, of which, on detailed review, 7 were true ...
Tópico(s): Cardiac Arrest and Resuscitation
2009 - Lippincott Williams & Wilkins | Pediatric Critical Care Medicine
Todd L. Demmy, Chukwumere Nwogu, Patrick D. Solan, Saikrishna Yendamuri, Gregory E. Wilding, Oscar DeLeon,
... every 6 hours by visual analog pain scales (VAPS, 100 mm). VAPS were repeated 10 minutes later to assess any ... related adverse events occurred. Compared with controls, pooled VAPS scores and 24-hour fentanyl consumption were significantly ... respective median; p = 0.04) Early (6-hour) VAPS analgesic responses were more certain for intermittent (10 ... 10, p = .04). Five continuous patients successfully maintained VAPS scores below 20 mm throughout the study vs ... every 6 hours by visual analog pain scales (VAPS, 100 mm). VAPS were repeated 10 minutes later ...
Tópico(s): Pain Management and Opioid Use
2009 - Elsevier BV | The Annals of Thoracic Surgery
Andrew Conway Morris, Kallirroi Kefala, Thomas S. Wilkinson, Olga Lucia Moncayo-Nieto, Kevin Dhaliwal, Lesley Farrell, Timothy Walsh, Stephen Mackenzie, David Swann, P. J. D. Andrews, N. Anderson, John R. W. Govan, Ian F. Laurenson, H. Reid, Donald J. Davidson, Christopher Haslett, Jean–Michel Sallenave, A. John Simpson,
Background Ventilator-associated pneumonia (VAP) is the most commonly fatal nosocomial infection. Clinical diagnosis of VAP remains notoriously inaccurate. The hypothesis was tested that significantly augmented inflammatory markers distinguish VAP from conditions closely mimicking VAP. Methods A prospective, observational cohort study was carried ... care units recruiting 73 patients with clinically suspected VAP, and a semi-urban primary care practice recruiting ... cfu)/ml of bronchoalveolar lavage fluid (BALF) distinguished VAP from "non-VAP". Inflammatory mediators were quantified in ...
Tópico(s): Respiratory Support and Mechanisms
2009 - BMJ | Thorax
Hung‐Yuan Li, Mao-Shin Lin, Jung-Nan Wei, Chi Sheng Hung, Fu‐Tien Chiang, Cheng-Hsin Lin, Hsiu-Ching Hsu, Chien-Yin Su, Mei-Yu Wu, David J. Smith, Jani Vainio, Ming-Fong Chen, Lee‐Ming Chuang,
... investigated if serum vascular adhesion protein-1 (SSAO/VAP-1) changed acutely following oral glucose loading and ... thickness (IMT) was measured by ultrasonography. Serum SSAO/VAP-1 was analyzed by time-resolved immunofluorometric assay. ... AGEs) were measured by fluorometric assays.Serum SSAO/VAP-1 increased significantly at 30 min after oral ... respectively). The area under curve of serum SSAO/VAP-1 during OGTT (AUC-VAP-1) correlated significantly with carotid IMT, independent of ... C-reactive protein. Subjects with a positive AUC-VAP-1 had significantly higher serum TBARS and AGEs ...
Tópico(s): Alcohol Consumption and Health Effects
2009 - Elsevier BV | Clinica Chimica Acta