Giles Tremlett, Cath Urquhart, Mike Gerrard, Nick Nuttall Environment Correspondent, Brian Greer, Portia Colwell, Alfred Dunhill, Patricia Davies, Adrian Lee, Patrick Grattan, Simon Barnes, John Morgan, Bill Frost, Christopher Spence, Richard Hobson, Ivo Tennant, Gavin Lumsden, Margaret Jay, Hilary Finch, Sarah Mower, Diana Mosley, John Wilbraham, Joanna Bale, Patrick Collinson, Brian Pedley, Rachel Campbell-Johnston, George Sivell, Lee Evans and David Long, Lynne Truss, Carl Mortished, Simon Wilde, Tony Patrick, Adam, Kevin Eason, Geoff Brown, Daniel McGrory and Lin Jenkins, Peter Brown, Louise Godfrey, John Thicknesse, Martin Fletcher, John Mortimer, Pat Gibson, John O'leary Education Editor, John B. D. Armstrong, Robert Sheehan, D. R., Janet Bush, Economics Editor, Norman Hammond, Archaeology Correspondent, Ruth Gledhill, Graham Duffill, Joanna Bale and Dalya Alberge, Hugh Leggatt, Richard Evans, Racing Correspondent, Rhodri Howell, Martin Barrow, Kenneth Stern, Marcelle D'argy Smith, Peter Waymark, Michael Evans, Defence Correspondent, Ian Morton, Alan Hamilton, Robin Young, Mike Rosewell Rowing Correspondent, Peter Millar, Matthew Beard and Thomas Harding, Jenny MacArthur, Helen Dunmore, Michael Clark, Cath Urquhart and Joanna Hunter, T. P., Kira Jolliffe, Sue Corbett, David Hands, P. B., Charles Bremner, Michael Cable, Peter Barnard, Michael Binyon Diplomatic Editor, Derwent May, Malcolm Smith, Lizanne Rose, Adam Sage and Richard Ford, Russell Kempson, Maria Harding, Ann Harris, Stephen Anderton, Philip Bassett, Sarah Johnson, Brian Jackman, Lisa Grainger, George Brock, Pittu Laungani, Bruce Andrews, John Hopkins, Lin Jenkins, Barry Millington, Simon de Bruxelles, Adam Jones, Paul Connew Deputy Editor, Christopher Blum, Jeffrey Bernard, Raymond Keene, Vaughan Freeman, David Charter, Education Correspondent, David Robinson, Kate Saunders, Alan Lee, Cricket Correspondent, John Russell Taylor, Matt Dickinson, P. W., Toby Kempster, Karen Zagor, James Allcock, P. H. S, Malcolm Wicks, Cardinal Basil Hume, Nigel Hawkes, Robin Neillands, Peter Orr, Bronwen Maddox, Oliver Holt, Michael Calvin, Damian Whitworth, Erica Wagner, Brian G. Birkhead, Alan Hamilton, Philip Webster and Daniel McGrory, Oliver August, Jo Foley, Sally Smith, Barbara Calvert, Stephanie Billen, Adam Fresco, Christopher Thomas, Anne Ashworth, Alan Copps, Christopher Walker, Robert Crampton, Chris Parker, Jane Shilling, P. G. Hartshorn, Julian Falkus, Jason Nissé, Kathryn Knight, Deborah King, Kevin McCarra, Andrew Yates, Louisa Young, Amanda Craig, Chris McGrath, Tim Wapshott, A. I. C. Black, Michael Austin, Alan Lee, Jane Owen, Peter Riddell, Ben MacIntyre, Donald Watt, Andy Martin, Russell Twisk, Alan Hamilton and Daniel McGrory, Richard Beeston, Tony Dawe, Nick Blanford, Daniel McGrory and Adrian Lee, Graham Searjeant, John Naish, Simon Jenkins, Fraser Nelson, Anne Ashworth Personal Finance Editor, Steve McManaman, Hattie Ellis, Andrew Pierce and Charles Bremner, Jason Cowley, David Sinclair, S. Gratwick, Heath Brown, Tunku Varadarajan and Carol Midgley, Benedict Nightingale, Sara McConnell and Lizanne Rose, Tom Rhodes, Jill Crawshaw's, Stuart Birch, Jack Bailey, Frances Gibb, David Powell, Tom Chesshyre, Elizabeth Buchan, Richard Morrison, Richard Attenborough, Valerie Grove, David Maddock, Michael Evans, Alan Jackson, Jim Soar, Nigel McCulloch, Anthony Howard, John Goodbody, Sports News Correspondent, David Hands, Rugby Correspondent, Richard Ford, P. K. Townley,
... protocol may prove to be a watershed, writes Valeria Grove The Times Millions to line route of ...
1997 - Gale Group | TDA
Alexander A. C. Leung, Adam Wright, Valeria Pazo, Andrew S. Karson, David W. Bates,
Background Although hyponatremia is a well-recognized complication of treatment with thiazide diuretics, the risk of thiazide-induced hyponatremia remains uncertain in routine care. Methods We conducted a retrospective cohort study using a multicenter clinical research registry to identify 2613 adult outpatients that were newly treated for hypertension between January 1, 2000 and December 31, 2005 at 2 teaching hospitals in Boston, Massachusetts, and followed them for up to 10 years. Results Two ...
Tópico(s): Renal function and acid-base balance
2011 - Elsevier BV | The American Journal of Medicine
Christopher J. Mathias, David A. Low, Valeria Iodice, Andrew P. Owens, Mojca Kirbiš, Rodney Grahame,
Tópico(s): Sympathectomy and Hyperhidrosis Treatments
2011 - Nature Portfolio | Nature Reviews Neurology
Kevin G. Daly, Valeria Mattiangeli, Andrew J. Hare, Hossein Davoudi, Homa Fathi, Sanaz Beizaee Doost, Sarieh Amiri, Roya Khazaeli, Delphine Decruyenaere, Jebrael Nokandeh, Tobias Richter, Hojjat Darabi, Peder Mortensen, Alexis Pantos, Lisa Yeomans, Pernille Bangsgaard, Marjan Mashkour, Melinda A. Zeder, Daniel G. Bradley,
The Aceramic Neolithic (∼9600 to 7000 cal BC) period in the Zagros Mountains, western Iran, provides some of the earliest archaeological evidence of goat (Capra hircus) management and husbandry by circa 8200 cal BC, with detectable morphological change appearing ∼1,000 y later. To examine the genomic imprint of initial management and its implications for the goat domestication process, we analyzed 14 novel nuclear genomes (mean coverage 1.13X) and 32 mitochondrial (mtDNA) genomes (mean coverage 143X) from ...
Tópico(s): Forensic and Genetic Research
2021 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Bethany Crouse, Mariah M. Wu, Valeria Gradinati, Andrew J. Kassick, Daihyun Song, Rajwana Jahan, Saadyah Averick, Scott P. Runyon, Sandra D. Comer, Marco Pravetoni,
Drug-related fatal overdoses have significantly increased in the past decade due to the widespread availability of illicit fentanyl and other potent synthetic opioids such as carfentanil. Deliberate or accidental consumption or exposure to carfentanil, fentanyl, and their mixture induces respiratory depression and bradycardia that can be difficult to reverse with the opioid receptor antagonist naloxone. Vaccines offer a promising strategy to reduce the incidence of fatalities associated with fentanyl- ...
Tópico(s): Neuropeptides and Animal Physiology
2022 - American Chemical Society | ACS Pharmacology & Translational Science
Sam Parsons, Flávio Azevedo, Mahmoud Medhat Elsherif, Samuel Guay, Owen N. Shahim, Gisela Govaart, Emma Norris, Aoife O’Mahony, Adam J Parker, Ana Todorović, Charlotte R. Pennington, Elias Garcia‐Pelegrin, Aleksandra Lazić, Olly Robertson, Sara L. Middleton, Beatrice Valentini, Joanne McCuaig, Bradley J. Baker, Elizabeth Collins, Adrien Fillon, Tina B. Lonsdorf, Michele C. Lim, Norbert Vanek, Márton Kovács, Timo B. Roettger, Sonia Rishi, Jacob Francisco Miranda, Matt Jaquiery, Suzanne Stewart, Valeria Agostini, Andrew Stewart, Kamil Izydorczak, Sarah Ashcroft-Jones, Helena Hartmann, Madeleine Ingham, Yuki Yamada, Martin R. Vasilev, Filip Děchtěrenko, Nihan Albayrak‐Aydemir, Yufang Yang, Annalise Aleta LaPlume, Julia Wolska, Emma Henderson, Mirela Zaneva, Benjamin Farrar, Ross Mounce, Tamara Kalandadze, Wanyin Li, Qinyu Xiao, Robert M. Ross, Siu Kit Yeung, Meng Liu, Micah Vandegrift, Zoltán Kekecs, Marta Topor, Myriam A. Baum, Emily A. Williams, Asma A. Assaneea, Amélie Bret, Aidan G Cashin, N. E. Ballou, Tsvetomira Dumbalska, Bettina Kern, Claire Melia, Beatrix Arendt, Gerald H. Vineyard, Jade Pickering, Thomas Rhys Evans, Catherine Laverty, Eliza A. Woodward, David Moreau, Dominique G. Roche, Eike Mark Rinke, Graham Reid, Eduardo García‐Garzón, Steven Verheyen, Halil Emre Kocalar, Ashley Blake, Jamie Philip Cockcroft, Leticia Micheli, Brice Beffara, Zoe M. Flack, Barnabás Szászi, Markus Weinmann, Óscar Lecuona, Birgit Schmidt, William Xiang Quan Ngiam, Ana Barbosa Mendes, Shannon Francis, Brett J. Gall, Mariella Paul, Connor Tom Keating, Magdalena Grose-Hodge, James E. Bartlett, Bethan Joan Iley, Lisa Spitzer, Madeleine Pownall, Christopher J Graham, Tobias Wingen, Jenny Terry, Catia Margarida Oliveira, Ryan A. Millager, Kerry J. Fox, Alaa Aldoh, Alexander Hart, Olmo R. van den Akker, Gilad Feldman, Dominik A. Kiersz, Christina Pomareda, Kai Krautter, Ali H. Al‐Hoorie, Balázs Aczél,
Open scholarship has transformed research, and introduced a host of new terms in the lexicon of researchers. The ‘Framework for Open and Reproducible Research Teaching’ (FORRT) community presents a crowdsourced glossary of open scholarship terms to facilitate education and effective communication between experts and newcomers.
Tópico(s): Open Education and E-Learning
2022 - Nature Portfolio | Nature Human Behaviour
Anne‐Catherine Andres, Nadia Munarini, Valentin Djonov, Salomé Bruneau, Gisela Zuercher, Saemi Loercher, Valeria Rohrbach, Andrew Ziemiecki,
Tópico(s): Zebrafish Biomedical Research Applications
2003 - Elsevier BV | Mechanisms of Development
Aymerick Eudes, Guus B. Erkens, Dirk Jan Slotboom, Dmitry A. Rodionov, Valeria Naponelli, Andrew D. Hanson,
Genes encoding high-affinity folate- and thiamine-binding proteins (FolT, ThiT) were identified in the Lactobacillus casei genome, expressed in Lactococcus lactis, and functionally characterized. Similar genes occur in many Firmicutes, sometimes next to folate or thiamine salvage genes. Most thiT genes are preceded by a thiamine riboswitch.
Tópico(s): RNA and protein synthesis mechanisms
2008 - American Society for Microbiology | Journal of Bacteriology
Fern Day, Lucia Valmaggia, Valeria Mondelli, Andrew Papadopoulos, Irene Papadopoulos, Carmine M. Pariante, Philip McGuire,
There is a consensus that stress plays a role in the onset of psychosis but the precise underlying mechanism remains unclear. The hypothalamic-pituitary-adrenal (HPA) axis is hypothesised to mediate the relationship between stress and psychosis and evidence indicates a potential role for the stress hormone cortisol as a biomarker of psychosis risk. We explored this hypothesis by examining the HPA axis in people at ultra-high risk (UHR) for psychosis and its relationship to symptoms. UHR (n = 52) and ...
Tópico(s): Mental Health Research Topics
2014 - Elsevier BV | Schizophrenia Research
Monica Z. Wang, Ping Jin, David Bumcrot, Valeria Marigo, Andrew P. McMahon, Elizabeth A. Wang, Tod M. Woolf, Kevin Pang,
Tópico(s): Pluripotent Stem Cells Research
1995 - Nature Portfolio | Nature Medicine
Julie Duboscq, Valéria Romano, Andrew J. J. MacIntosh, Cédric Sueur,
The capacity to use information provided by others to guide behavior is a widespread phenomenon in animal societies. A standard paradigm to test if and/or how animals use and transfer social information is through social diffusion experiments, by which researchers observe how information spreads within a group, sometimes by seeding new behavior in the population. In this article, we review the context, methodology and products of such social diffusion experiments. Our major focus is the transmission ...
Tópico(s): Primate Behavior and Ecology
2016 - Frontiers Media | Frontiers in Psychology
Valéria Salvatori, Andrew K. Skidmore, F. Corsi, F.D. van der Meer,
Radio-telemetry is an excellent tool for gathering data on the biology of animals and their interactions with the environment they inhabit. Many methods have been developed for analyses of spatial information, on home range size and utilization density. Activity patterns are often described using radio-tracking data, but no generally accepted method is currently available specifically for determining the temporal independence of this type of data for statistical inference. Activity rhythms have ...
Tópico(s): Isotope Analysis in Ecology
1999 - Elsevier BV | Journal of Theoretical Biology
Valeria Selyuzhenok, Andrew R. Mahoney, Thomas Krumpen, Giulia Castellani, Rüdiger Gerdes,
Accurate representation of fast ice in numerical models is important for realistic simulation of numerous sea-ice and ocean variables. In order to simulate seasonal and interannual variability of fast-ice extent, the mechanisms controlling fast-ice development need to be thoroughly understood. The objective of this paper is to investigate mechanisms contributing to the advance of fast-ice edge to its winter location in the south-eastern Laptev Sea. The study is based on time series of synthetic ...
Tópico(s): Oceanographic and Atmospheric Processes
2017 - Wiley | Polar Research
Julian Tillmann, Karen L. Ashwood, Michael Absoud, Sven Bölte, Frédérique Bonnet‐Brilhault, Jan K. Buitelaar, Sara Calderoni, Rosa Calvo, Ricardo Canal‐Bedia, Roberto Canitano, Annelies de Bildt, Marie Gomot, Pieter J. Hoekstra, Anett Kaale, Helen McConachie, Declan Murphy, Antonio Narzisi, Iris J. Oosterling, Milica Pejović-Milovančević, Antonio M. Persico, Olga Puig, Herbert Roeyers, Nanda Rommelse, Roberto Sacco, Valeria Scandurra, Andrew C. Stanfield, Eric Zander, Tony Charman,
Research on sex-related differences in Autism Spectrum Disorder (ASD) has been impeded by small samples. We pooled 28 datasets from 18 sites across nine European countries to examine sex differences in the ASD phenotype on the ADI-R (376 females, 1763 males) and ADOS (233 females, 1187 males). On the ADI-R, early childhood restricted and repetitive behaviours were lower in females than males, alongside comparable levels of social interaction and communication difficulties in females and males. Current ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2018 - Springer Science+Business Media | Journal of Autism and Developmental Disorders
Armando Stabile, Francesco Giganti, Veeru Kasivisvanathan, Gianluca Giannarini, Caroline M. Moore, Anwar R. Padhani, Valeria Panebianco, Andrew B. Rosenkrantz, Georg Salomon, Barış Türkbey, Geert Villeirs, Jelle O. Barentsz,
There is a lack of comprehensive data regarding the factors that influence the diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) to detect and localize clinically significant prostate cancer (csPCa). To systematically review the current literature assessing the factors influencing the variability of mpMRI performance in csPCa diagnosis. A computerized bibliographic search of Medline/PubMed database was performed for all studies assessing magnetic field strength, use of an endorectal ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2020 - Elsevier BV | European Urology Oncology
Valéria Romano, Andrew J. J. MacIntosh, Cédric Sueur,
Social information and socially transmitted pathogens are governed by social structure, and also shape social interactions. However, information and infection are rarely investigated as interactive factors driving social evolution. We propose exactly such an integrative framework, drawing attention to mechanisms of social phenotypic plasticity for information spread and pathogen control.
Tópico(s): Language and cultural evolution
2020 - Elsevier BV | Trends in Ecology & Evolution
Valeria Lulla, Andrew E. Firth,
Abstract Human astroviruses are small non-enveloped viruses with positive-sense single-stranded RNA genomes. Astroviruses cause acute gastroenteritis in children worldwide and have been associated with encephalitis and meningitis in immunocompromised individuals. It is still unknown how astrovirus particles exit infected cells following replication. Through comparative genomic analysis and ribosome profiling we here identify and confirm the expression of a conserved alternative-frame ORF, encoding ...
Tópico(s): Virus-based gene therapy research
2020 - Nature Portfolio | Nature Communications
Paola Fugazzola, Lorenzo Cobianchi, Marcello Di Martino, Matteo Tomasoni, Francesca Dal Mas, Fikri M. Abu‐Zidan, Vanni Agnoletti, Marco Ceresoli, Federico Coccolini, Salomone Di Saverio, Tommaso Dominioni, Camilla Nikita Farè, Simone Frassini, Giulia Gambini, Ari Leppäniemi, Marcello Maestri, Elena Martín‐Pérez, Ernest E. Moore, Valeria Musella, Andrew B. Peitzman, Ángela de la Hoz Rodríguez, Benedetta Sargenti, Massimo Sartelli, Jacopo Viganò, Andrea Anderloni, Walter Biffl, Fausto Catena, Luca Ansaloni, Goran Augustin, Trpimir Morić, Selmy Awad, Azzah M. Alzahrani, Mohamed Elbahnasawy, Damien Massalou, Belinda De Simone, Zaza Demetrashvili, Athina‐Despoina Kimpizi, Dimitriοs Schizas, Dimitrios Balalis, Nikolaos Tasis, Maria Papadoliopoulou, Petrakis Georgios, Konstantinos Lasithiotakis, Orestis Ioannidis, Lovenish Bains, Matteo Magnoli, Pasquale Cianci, Nunzia Ivana Conversano, Alessandro Pasculli, Jacopo Andreuccetti, Elisa Arici, Giusto Pignata, Guido Alberto Massimo Tiberio, Mauro Podda, Cristina Murru, Massimiliano Veroux, Costanza Distefano, Danilo Centonze, Francesco Favi, Raffaele Bova, Girolamo Convertini, Andrea Balla, Diego Sasia, Giorgio Giraudo, Gabriele Anania, Nicola Tartaglia, Giovanna Pavone, Fabrizio D’Acapito, Nicolò Fabbri, Francesco Ferrara, Stefania Cimbanassi, Luca Ferrario, Stefano Piero Bernardo Cioffi, Marco Ceresoli, Chiara Fumagalli, Luca Degrate, Maurizio Degiuli, Silvia Sofia, Leslie Claire Licari, Mario Improta, Alberto Patriti, Diego Coletta, Luigi Conti, Michele Malerba, Andrea Muratore, Marcello Calabrò, Beatrice De Zolt, Gabriele Bellio, Alessio Giordano, Davide Luppi, Carlo Corbellini, Gianluca M. Sampietro, Chiara Marafante, Stefano Rossi, Andrea Mingoli, Pierfrancesco Lapolla, Pierfranco M. Cicerchia, Leandro Siragusa, Michele Grande, Claudio Arcudi, Amedeo Antonelli, Danilo Vinci, Ciro De Martino, Mariano Fortunato Armellino, Enrica Bisogno, Diego Visconti, Mauro Santarelli, Elena Montanari, Alan Biloslavo, Paola Germani, Claudia Zaghi, Naoki Oka, Mohd Azem Fathi, Daniel Ríos‐Cruz, Edgard Efrén Lozada Hernández, Ibrahım Umar Garzali, Liliana Duarte, Ionuţ Negoi, Andrey Litvin, Sharfuddin Chowdhury, Salem M. Alshahrani, Silvia Carbonell Morote, Juan Jesus Rubio‐García, Claudia Cristina Lopes Moreira, Íñigo Augusto Ponce, Fernando Mendoza‐Moreno, Anna Muñoz Campaña, Heura Llaquet Bayo, Andrea Campos‐Serra, Aitor Landaluce-Olavarria, Mario Serradilla‐Martín, Antonio Cano-Paredero, Miguel Ángel Dobón Rascón, Hytham K. S. Hamid, Oussama Baraket, Emre Gönüllü, Sezai Leventoğlu, Yılmaz Türk, Çağrı Büyükkasap, Ulaş Aday, Yasi̇n Kara, Hamit Ahmet Kabuli, Semra Demirli Atıcı, Elif Çolak, S. Chooklin, S.S. Chuklin, Federico Ruta, Begoña Estraviz‐Mateos, Izaskun Markinez‐Gordobil,
Abstract Background Less invasive alternatives than early cholecystectomy (EC) for acute calculous cholecystitis (ACC) treatment have been spreading in recent years. We still lack a reliable tool to select high-risk patients who could benefit from these alternatives. Our study aimed to prospectively validate the Chole-risk score in predicting postoperative complications in patients undergoing EC for ACC compared with other preoperative risk prediction models. Method The S.P.Ri.M.A.C.C. study is a ...
Tópico(s): Abdominal Trauma and Injuries
2023 - BioMed Central | World Journal of Emergency Surgery
Roelinda Jongstra, Md Mokbul Hossain, Valeria Galetti, Andrew G Hall, Roberta R. Holt, Colin I. Cercamondi, Sabina Faiz Rashid, Michael Zimmermann, Malay Kanti Mridha, Rita Wegmueller,
Zinc biofortification of rice could sustainably improve zinc status in countries where zinc deficiency is common and rice is a staple, but its efficacy has not been tested. Fatty acid desaturases (FADS) are putative new zinc status biomarkers. Our objective was to test the efficacy of zinc-biofortified rice (BFR) in preschool-aged children with zinc deficiency. Our hypothesis was that consumption of BFR would increase plasma zinc concentration (PZC). We conducted a 9-mo, double-masked intervention ...
Tópico(s): Plant Micronutrient Interactions and Effects
2021 - Elsevier BV | American Journal of Clinical Nutrition
Loretta J. Nastoupil, Georg Heß, Miguel Arturo Pavlovsky, Iwona Danielewicz, Jane A. Freeman, Alejandro Martı́n, Valeria Glazunova, Andrew Grigg, Jing‐Zhou Hou, Ann Janssens, Seok Jin Kim, Zvenyslava Masliak, Pam McKay, Francesco Merli, Wataru Munakata, Hirokazu Nagai, Muhıt Özcan, Meir Preis, Tingyu Wang, Melissa Rowe, Monelle Tamegnon, Rui Qin, Todd Henninger, Madeliene Curtis, Donne Bennett Caces, Catherine Thiéblemont, Gilles Salles,
Abstract The phase 3 SELENE study evaluated ibrutinib + chemoimmunotherapy (CIT; bendamustine and rituximab [BR]; or rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone [R-CHOP]) for patients with relapsed/refractory (R/R) follicular lymphoma (FL) or marginal zone lymphoma (MZL). Adult patients who had received ≥1 prior line of CIT were randomized 1:1 to oral ibrutinib (560 mg) or placebo daily, plus 6 cycles of BR/R-CHOP. The primary end point was investigator-assessed progression-free ...
Tópico(s): Viral-associated cancers and disorders
2023 - Elsevier BV | Blood Advances
Rory M. Shallis, Naval Daver, Jessica K. Altman, Robert P. Hasserjian, Hagop M. Kantarjian, Uwe Platzbecker, Valeria Santini, Andrew H. Wei, David A. Sallman, Amer M. Zeidan,
Abstract TP5 3 ‐altered myelodysplastic syndrome with excess blasts and TP53 ‐altered acute myeloid leukemia should be considered under one unifying classification term for their study in clinical trials. Ultimately, such a unification would simplify the screening processes for clinical trials and allow a focus on treating the patient for a genetically defined disorder rather than one based on an arbitrary blast threshold.
Tópico(s): Hematopoietic Stem Cell Transplantation
2022 - Wiley | Cancer
Mayada Tassabehji, Valeria E. Newton, Andrew Read,
Tópico(s): Ocular Disorders and Treatments
1994 - Nature Portfolio | Nature Genetics
Maria Valéria Robles Velasco, Andrew A. Colin, David Zurakowski, Basil T. Darras, Frederic Shapiro,
In Brief Study Design. To assess the rate of decline in pulmonary function in Duchenne muscular dystrophy (DMD) before and after posterior spinal fusion for scoliosis. Objective. To compare the rate of respiratory decline using percent normal forced vital capacity (%FVC) measurements before and after posterior spinal fusion. Summary of Background Data. Posterior spinal fusion for scoliosis is used widely in DMD, although the long-term pulmonary effects have not been well established. Methods. Fifty- ...
Tópico(s): Prosthetics and Rehabilitation Robotics
2007 - Lippincott Williams & Wilkins | Spine
Valeria Silva Merea, Andrew H. Y. Lee, Didier L. Peron, Erik H. Waldman, Eli Grunstein,
Objectives/Hypothesis Congenital pyriform aperture stenosis (CPAS) is a form of nasal obstruction caused by congenital narrowing of the maxilla at the medial processes. Traditionally, surgical correction involves a sublabial approach with subperiosteal dissection, widening of the aperture by drilling, and the use of nasal stents postoperatively. Although this approach may lead to symptomatic improvement, it alone may fail to provide a patent airway secondary to unaddressed posterior narrowing. Additionally, ...
Tópico(s): Ocular Disorders and Treatments
2014 - Wiley | The Laryngoscope
Nkosiphile Bhebhe, Peter A. C. Williams, Carmelo Rosales‐Guzmán, Valeria Rodríguez-Fajardo, Andrew Forbes,
The invention of optical tweezers almost forty years ago has triggered applications spanning multiple disciplines and has also found its way into commercial products. A major breakthrough came with the invention of holographic optical tweezers (HOTs), allowing simultaneous manipulation of many particles, traditionally done with arrays of scalar beams. Here we demonstrate a vector HOT with arrays of digitally controlled Higher-Order Poincaré Sphere (HOPS) beams. We employ a simple set-up using a spatial ...
Tópico(s): Microfluidic and Bio-sensing Technologies
2018 - Nature Portfolio | Scientific Reports
Jonathan Pinnell, Valeria Rodríguez-Fajardo, Andrew Forbes,
Perfect (optical) vortices (PVs) have the mooted ability to encode orbital angular momentum (OAM) onto the field within a well-defined annular ring. Although this makes the near-field radial profile independent of OAM, the far-field radial profile nevertheless scales with OAM, forming a Bessel structure. As yet, the quantitative measurement of the OAM of PVs has been elusive, with current detection protocols opting for more qualitative procedures using interference or mode sorters. Here, we show that ...
Tópico(s): Cold Atom Physics and Bose-Einstein Condensates
2019 - Optica Publishing Group | Optics Letters
Stirling Scholes, Ravin Kara, Jonathan Pinnell, Valeria Rodríguez-Fajardo, Andrew Forbes,
Digital micromirror devices (DMDs) have become ubiquitous as spatial light modulators in the optics community, but ambiguity remains on how best to implement them in a laboratory environment. Here, we explicitly tackle the problem of generating high fidelity modes of structured light while maintaining optical efficiency. We present a theoretical characterization of the diffractive properties of the DMD, allowing us to motivate an alignment procedure that improves optical efficiency. We also present ...
Tópico(s): Photonic and Optical Devices
2019 - SPIE | Optical Engineering
Jonathan Pinnell, Valeria Rodríguez-Fajardo, Andrew Forbes,
Perfect (optical) vortex (PV) beams are fields which are mooted to be independent of the orbital angular momentum (OAM) they carry. To date, the best experimental approximation of these modes is obtained from passing Bessel-Gaussian beams through a Fourier lens. However, the OAM-dependent width of these quasi-PVs is not precisely known and is often understated. We address this here by deriving and experimentally confirming an explicit analytic expression for the second moment width of quasi-PVs. We ...
Tópico(s): Cold Atom Physics and Bose-Einstein Condensates
2019 - Optica Publishing Group | Optics Letters
Jonathan Pinnell, Valeria Rodríguez-Fajardo, Andrew Forbes, Saoussene Chabou, Karima Mihoubi, Abdelhalim Bencheikh,
In this paper, we propose a predictor or indicator of the self-healing ability of coherent structured light beams: the field's modal content. Specifically, the fidelity between the obstructed and unobstructed beams' modal spectrum serves as a useful measure of the degree to which the beam will likely self-heal after an arbitrary obstacle. Since any optical field can be decomposed in terms of any chosen orthonormal basis, this analysis is, therefore, less restrictive than other methods for determining ...
Tópico(s): Advanced Fiber Laser Technologies
2020 - American Physical Society | Physical review. A/Physical review, A
Jonathan Pinnell, Valeria Rodríguez-Fajardo, Andrew Forbes,
Spatial light modulators (SLMs) are popular tools for generating structured light fields and have fostered numerous applications in optics and photonics. Here, we explore the limits of what fields these devices are capable of generating and detecting in the context of so-called vortex beams carrying orbital angular momentum (OAM). Our main contributions are to quantify (theoretically and experimentally) how the pixelation of the SLM screen affects the quality of the generated vortex mode and to offer ...
Tópico(s): Plasmonic and Surface Plasmon Research
2020 - IOP Publishing | Journal of Optics