Produção Nacional
Revisado por pares
José Sebastião Cunha Fernandes, Ricardo Siqueira da Silva, Alexandre Christófaro Silva, Daniel C. Villela, Vanessa Amaral Mendonça, Ana Cristina Rodrigues Lacerda,
Abstract COVID-19 is spreading rapidly in Brazil, a country of continental dimensions, but the incidence of the disease is showing to be very heterogeneous, affecting cities and regions differently. Thus, there is a gap regarding what factors would contribute to accentuate the differences in the incidence of COVID-19 among Brazilian cities. This work aimed to evaluate the effect of altitude on the incidence of COVID-19 in Brazilian cities. We analyzed the relative incidence (RI), the relative death ...
Tópico(s): COVID-19 Clinical Research Studies
2021 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Maria P Villela, Vanessa L. Andrade, Bryelle Eccard, Alceu Afonso Jordão, Jonas T. Sertório, José E. Tanus‐Santos, Iêda de Fátima Oliveira Silva, Josianne Nicácio Silveira, Valéria C. Sandrim,
Summary Higher homocysteine (Hcy) levels are associated with cardiovascular risk. The aim of the present study was to evaluate the effect of simvastatin treatment on circulating Hcy levels in obese women without hypertension, diabetes or dyslipidaemia; and to determine whether the 677C>T polymorphism located in methylenetetrahydrofolate reductase ( NAD (P)H) ( MTHFR ) gene modulates the effects of this treatment on Hcy and nitrite (as a biomarker of nitric oxide ( NO ) bioavailability). Twenty‐five obese ...
Tópico(s): Pregnancy and preeclampsia studies
2014 - Wiley | Clinical and Experimental Pharmacology and Physiology
Produção Nacional
Revisado por pares
Mariana M.V.M. Souza, Sônia Silva Marcon, Sônia Maria Villela Bueno, Lígia Carreira, Vanessa Denardi Antoniassi Baldissera,
O objetivo deste trabalho foi descrever a vivência da sexualidade por mulheres idosas viúvas, frequentadoras de um Centro de Convivência do Idoso, e verificar a percepção quanto à opinião dos seus familiares. Tratou-se de uma pesquisa qualitativa e exploratório-descritiva. Os dados foram coletados por meio de entrevistas semiestruturadas e submetidos à análise de conteúdo temática. Emergiram desta as categorias: 1) a vivência da sexualidade sofreu algumas modificações após o estado de viuvez garantindo ...
Tópico(s): Reproductive Health and Technologies
2015 - UNIVERSIDADE DE SÃO PAULO | Saúde e Sociedade
Produção Nacional
Revisado por pares
Fabiano Carlos Ferreira, Francisco Amaral Villela, Géri Eduardo Meneghello, Vanessa Nogueira Soares,
Abstract: The aim of this study was to evaluate the physiological quality of soybean seeds submitted or not to dynamic cooling, and kept in cold storage (CS) and non-cold storage (NCS). A soybean seeds lot, variety M7639RR, was divided into two parts, and each one was subdivided into three parts that were subjected to one of these cooling procedure: seeds without cooling (SWC), dynamic cooling at 17 °C (SC17), and dynamic cooling at 13 °C (SC13). Seeds were kept in CS and NCS at 20 °C. Samples were collected ...
Tópico(s): Growth and nutrition in plants
2017 - Associação Brasileira de Tecnologia de Sementes | Journal of Seed Science
Produção Nacional
Revisado por pares
Iara Sescon Nogueira, Célia Maria Gomes Labegalini, Karen Fernanda Ramos Pereira, Ieda Harumi Higarashi, Sônia Maria Villela Bueno, Vanessa Denardi Antoniassi Baldissera,
Objetivou-se descrever o percurso de uma ação educativa contextualizada, participativa e dialógica na temática sexualidade. Trata-se de estudo qualitativo do tipo pesquisa-ação crítica, delineado seguindo o referencial teórico-metodológico de Freire, tendo como público alvo 151 alunos matriculados no curso de graduação em enfermagem de uma universidade pública do Noroeste do Estado do Paraná, durante o mês de março de 2014. Destes, participaram 20 acadêmicos na fase de investigação temática e nove ...
Tópico(s): Gender, Sexuality, and Education
2017 - UNIVERSIDADE FEDERAL DO PARANÁ | Cogitare Enfermagem
Produção Nacional
Revisado por pares
Ana Carolina Campi‐Azevedo, Paula de Almeida Estevam, Jordana Grazziela Coelho-dos-Reis, Vanessa Peruhype-Magalhães, Gabriela Villela-Rezende, Patrícia Flávia Quaresma, Maria de Lourdes Sousa Maia, Roberto Farias, Luiz Antônio Bastos Camacho, Marcos da Silva Freire, Ricardo Galler, Anna M. Y. Yamamura, Luiz F.C. Almeida, Sheila Maria Barbosa de Lima, Rita Maria Ribeiro Nogueira, Glória Regina Silva e Sá, Darcy Akemi Hokama, Ricardo de Souza Carvalho, Ricardo Aguiar Villanova Freire, Edson Pereira Filho, M Leal, Akira Homma, Andréa Teixeira‐Carvalho, Reinaldo de Menezes Martins, Olindo Assis Martins‐Filho,
The live attenuated 17DD Yellow Fever vaccine is one of the most successful prophylactic interventions for controlling disease expansion ever designed and utilized in larger scale. However, increase on worldwide vaccine demands and manufacturing restrictions urge for more detailed dose sparing studies. The establishment of complementary biomarkers in addition to PRNT and Viremia could support a secure decision-making regarding the use of 17DD YF vaccine subdoses. The present work aimed at comparing ...
Tópico(s): Viral Infections and Vectors
2014 - BioMed Central | BMC Infectious Diseases
Produção Nacional
Revisado por pares
Letícia de Paula Scalioni, Helena Medina Cruz, Vanessa Salete de Paula, Juliana Custódio Miguel, Vanessa Alves Marques, Cristiane Alves Villela‐Nogueira, Flavio Augusto de Pádua Milagres, Marcelo Santos Cruz, Francisco Inácio Bastos, Tarcísio Matos de Andrade, Ana Rita Coimbra Motta-Castro, Lia Laura Lewis‐Ximenez, Elisabeth Lampe, Lívia Melo Villar,
Rapid tests for the detection of antibodies to hepatitis C virus (anti-HCV) can facilitate access to diagnosis. This study aimed to evaluate the performance of rapid tests for anti-HCV detection in the sera, whole blood, and oral fluid samples from individuals with different endemicity profiles and risk behaviors. Three groups donated biological samples that were tested using three anti-HCV rapid tests (WAMA, Bioeasy and OraSure): (I) suspected cases of hepatitis C, (II) individuals who were living ...
Tópico(s): HIV/AIDS drug development and treatment
2014 - Elsevier BV | Journal of Clinical Virology
Produção Nacional
Revisado por pares
Camille Petruccio Urago Brandão, B.L.C. Marques, Vanessa Alves Marques, Cristiane Alves Villela‐Nogueira, K.M.R. Do Ó, M.T. de Paula, Lia Laura Lewis‐Ximenez, Elisabeth Lampe, Jennifer Ferreira, Lívia Melo Villar,
Enzyme immunoassays (EIA) designed to detect hepatitis C virus (HCV) core antigen and anti-HCV antibodies (HCV AgAb) simultaneously can improve the early detection of HCV infection when molecular diagnostic methods are not widely available.To evaluate the suitability of dried blood spot (DBS) samples for detecting HCV AgAb using commercial EIAs.Paired serum and DBS samples were assayed using two commercial EIAs for HCV AgAb (Monolisa™ HCV AgAb ULTRA and Murex HCV AgAb). Manufacturer's recommendations ...
Tópico(s): Blood groups and transfusion
2013 - Elsevier BV | Journal of Clinical Virology
Produção Nacional
Revisado por pares
Helena Medina Cruz, Vanessa Alves Marques, Cristiane Alves Villela‐Nogueira, K. M. R. do Ó, Lia Laura Lewis‐Ximenez, Elisabeth Lampe, Lívia Melo Villar,
J Oral Pathol Med (2012) 41 : 793–800 Background: Saliva samples can be used as an alternative fluid for against hepatitis C virus (anti‐HCV) detection owing to the ease of collection and excellent acceptability. This study was conducted to optimize a commercial enzyme immunoassay (EIA) to detect anti‐HCV in saliva samples. Methods: Ninety‐six individuals donated paired serum and saliva samples that were obtained, using a commercial device (Salivette) and spitting into a sterile container. Initially, ...
Tópico(s): Protein purification and stability
2012 - Wiley | Journal of Oral Pathology and Medicine
Produção Nacional
Revisado por pares
B.L.C. Marques, Cardoso Brandão, E.F. Silva, Vanessa Alves Marques, Cristiane Alves Villela‐Nogueira, K.M.R. Do Ó, M.T. de Paula, Lia Laura Lewis‐Ximenez, Elisabeth Lampe, Lívia Melo Villar,
This study was undertaken to optimize and compare the efficiency of two commercial EIAs for anti-HCV detection (HCV Ab Radim, Pomezzia, Italy and ETI-AB-HCVK-4 DiaSorin, Vercelli, Italy), in dried blood spot (DBS) samples. The long-term stability of anti-HCV on DBS samples stored at three environmental conditions was also evaluated at: 2-8 °C, 20-25 °C, and -20 °C. Paired DBS and serum samples were obtained from individuals with or without anti-HCV. The type of elution buffer, sample and conjugate volume, ...
Tópico(s): Hepatitis B Virus Studies
2012 - Wiley | Journal of Medical Virology
Produção Nacional
Revisado por pares
Carla Cristina Villela Desagiacomo, Robson Carlos Alnoch, Vanessa Elisa Pinheiro, Mariana Cereia, Carla Botelho Machado, André Damásio, Marlei Josiele Augusto, Wellington Ramos Pedersoli, Roberto Nascimento Silva, Maria de Lourdes Teixeira de Moraes Polizeli,
A purified exo-polygalacturonase of Neosartorya glabra (EplNg) was successfully characterized. EplNg native presented 68.2 kDa, with 32% carbohydrate content. The deglycosylated form showed 46.3 kDa and isoelectric point of 5.4. The identity of EplNg was confirmed as an exo-polygalacturonase class I (EC 3.2.1.67) using mass spectrometry and Western-Blotting. Capillary electrophoresis indicated that only galacturonic acid was released by the action of EplNg on sodium polypectate, confirming an exoenzyme ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2021 - Elsevier BV | International Journal of Biological Macromolecules
Produção Nacional
Revisado por pares
Lílian Vanussa Madruga de Tunes, Andréia da Silva Almeida, Géri Eduardo Meneghello, Francisco Amaral Villela, Vanessa Nogueira Soares, Murilo Bortolotti,
Vegetable seeds have high commercial value, in the field after sowed seeds were exposed to unfavorable environmental conditions capable of causing reductions in the yield. Thiamethoxam is a bio-activator that may confer tolerance to stresses. In this regard, we aimed to evaluate the influence of thiamethoxam in the physiological performance of four lots of tomato and onion seeds. Seeds were treated with five doses of thiamethoxam, 0.0; 0.2; 0.4; 0.6 and 0.8 ml of product per 1000 seeds. The effects ...
Tópico(s): Seed Germination and Physiology
2018 - | Comunicata Scientiae
Produção Nacional
Elton Carlos de Almeida, Sônia Maria Villela Bueno, Vanessa Antoniassi Denardi Baldissera,
Objetivou-se conhecer a atuação profissional no processo de doação de órgãos na perspectiva do familiar. Realizou-se metassíntese qualitativa de estudos brasileiros publicados entre 2001 a janeiro de 2015 veiculados na PubMed, SCOPUS, CINAHL, EMBASE, Web of Science, Science Direct, LILACS, BDENF. Resultando em 273 trabalhos, que após levantamento efetivo e exaustivos, resultaram sete artigos, os quais foram selecionados e submetidos à leitura criteriosa quanto à metodologia utilizada, sujeitos investigados, ...
Tópico(s): Palliative and Oncologic Care
2015 - | Arquivos de Ciências da Saúde da UNIPAR
Produção Nacional
Revisado por pares
Geane Lopes Flores, Helena Medina Cruz, Vanessa Alves Marques, Cristiane Alves Villela‐Nogueira, Denise Vigo Potsch, Silvia Beatriz May, Carlos Eduardo Brandão‐Mello, Marcia Maria Amêndola Pires, José Henrique Pilotto, Priscila Pollo‐Flores, Eliane Bordalo Cathalá Esberard, Cláudia Alexandra Pontes Ivantes, Lia Laura Lewis‐Ximenez, Elisabeth Lampe, Lívia Melo Villar,
The use of saliva and dried blood spots (DBS) could increase access to HCV diagnosis for high‐risk populations, such as HIV‐infected individuals, but the performance of these assays has not been well established in this group. This study aims to evaluate HIV status, particularly TCD4 + cell count and viral load, in the performance of anti‐HCV testing using DBS and saliva. A total of 961 individuals classified as HCV+, HIV+, or HIV/HCV+, as well as negative controls, donated serum, DBS, and saliva samples ...
Tópico(s): Hepatitis B Virus Studies
2017 - Wiley | Journal of Medical Virology
Produção Nacional
Revisado por pares
Vanessa Denardi Antoniassi Baldissera, Sônia Maria Villela Bueno, Luíza Akiko Komura Hoga,
The purpose of this action research (AR) was to explore the ways in which sexuality is experienced daily and to improve the expression of older women's sexuality. The pedagogy of autonomy as proposed by the Brazilian educator Paulo Freire theoretically supported this AR, with the participation of six older adult women living in a rural setting in southwest Brazil. The older women's experiences regarding sexuality, their concerns, and their educational demands could be summarized through five phrases: ...
Tópico(s): Sexuality, Behavior, and Technology
2012 - Taylor & Francis | Health Care For Women International
Produção Nacional
Revisado por pares
Vanessa Elisa Pinheiro, Carla Cristina Villela Desagiacomo, Michele Michelin, Alexandre Maller, Lummy Maria Oliveira Monteiro, João Atı́lio Jorge, Maria de Lourdes Teixeira de Moraes Polizeli,
Summary Polygalacturonases are enzymes with the biotechnological potential for use in fruit juice clarification and for the enhancement of filtration efficiency. The aim of this work was to assess the production of polygalacturonase by the fungus Neosartorya glabra by means of solid-state and submerged fermentation using fruit peel residues as the carbon source, and also apply the enzyme in the clarification and decrease in viscosity of passion fruit and apple juices. The highest polygalacturonase ( ...
Tópico(s): Polysaccharides Composition and Applications
2017 - INSTITUTO DE TECNOLOGIA DE ALIMENTOS | Brazilian journal of food technology/Brazilian Journal of Food Technology
Produção Nacional
Revisado por pares
Lyana Rodrigues Pinto Lima, Luis Eduardo Barros Costa Fernandes, Daniel Antunes Maciel Villela, Mariza Gonçalves Morgado, José Henrique Pilotto, Vanessa Salete de Paula,
Pregnant women who are infected with the Human Immunodeficiency Virus (HIV) are particularly vulnerable to severe and recurrent infections with Human Herpesvirus 2 (HHV-2). Neonatal transmission of HHV-2 has been associated with malformations and neurological sequelae in infants, which makes it very important to perform antenatal monitoring for genital herpes. In the study, 134 pregnant women infected with HIV were tested for HHV-2 IgM and IgG using an enzyme-linked immunosorbent assay (ELISA) and ...
Tópico(s): Viral-associated cancers and disorders
2017 - Taylor & Francis | AIDS Care
Aérica Edna Ferreira, Bárbara Santos Ferreira, Melina Maria Burgarelli Lages, Vanessa Ayala Felício Rodrigues, Nísia Andrade Villela Dessimoni Pinto,
Tópico(s): Growth and nutrition in plants
2012 - UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO | Alimentos e Nutrição
Produção Nacional
Revisado por pares
Marina Scarulis Mamede dos Santos, Marislei Sanches Panobianco, Marli Villela Mamede, Maria Cristina Cortez Carneiro Meirelles, Vanessa Mundim e Barros,
OBJETIVO: identificar a alteração de sensibilidade no trajeto do nervo intercostobraquial utilizando um estesiômetro e observar a repetição das medições efetuadas com esse aparelho. MÉTODOS: foi aplicado o estesiômetro de Semmes-Weinstein para a avaliação da sensibilidade no trajeto do nervo intercostobraquial. Participaram desse estudo 94 mulheres divididas em dois grupos: Grupo CA, composto por 47 mulheres submetidas à linfonodenectomia axilar por câncer de mama, e grupo comparativo, composto ...
Tópico(s): Nonmelanoma Skin Cancer Studies
2009 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia
Produção Nacional
Revisado por pares
Célia Maria Gomes Labegalini, Iara Sescon Nogueira, Daysi Mara Murio Ribeiro Rodrigues, Elton Carlos de Almeida, Sônia Maria Villela Bueno, Vanessa Denardi Antoniassi Baldissera,
RESUMO Objetivo Analisar o percurso da educação dialógica sobre lazer e saúde mental desenvolvida em mídia virtual. Método Pesquisa-ação pautada no referencial teórico-metodológico Freireano, desenvolvida com 11 acadêmicos de enfermagem de uma universidade pública do estado do Paraná-BR, durante sete dias do mês de junho/2015, por meio de grupo fechado na mídia virtual Facebook®, cujos diálogos foram denominados “Círculos de Cultura Virtuais”, precedidos de questionários auto aplicados que versavam ...
Tópico(s): Education and Digital Technologies
2016 - UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL | Revista gaúcha de enfermagem
Produção Nacional
Revisado por pares
Vanessa Denardi Antoniassi Baldissera, Sônia Maria Villela Bueno,
People with hypertension constantly deal with issues related to mental health due to the psychosocial determinants of this illness, and leisure is an important control strategy. The objective of this study was to promote health education to a group of hypertensive patients, through research-action, based on critical-social pedagogy, and taking into consideration the participants' perception of leisure. Educational activities were conducted and, following, an evaluation was performed regarding the ...
Tópico(s): Physical Education and Sports Studies
2012 - UNIVERSIDADE DE SÃO PAULO | Revista da Escola de Enfermagem da USP
Produção Nacional
Revisado por pares
Moyra Machado Portilho, Ana Carolina da Fonseca Mendonça, Cristianne Sousa Bezerra, Márcia Paschoal do Espírito-Santo, Vanessa Salete de Paula, Letícia Cancella Nabuco, Cristiane Alves Villela‐Nogueira, Lia Laura Lewis‐Ximenez, Elisabeth Lampe, Lívia Melo Villar,
For quantification of hepatitis B virus DNA (HBV DNA), commercial assays are used with serum or plasma samples, but oral fluid samples could be an alternative for HBV diagnosis due to ease of collection. This study aims to develop in-house real time PCR using synthetic curve for HBV DNA quantification for serum and oral fluid samples. Samples were collected from 103 individuals (55 HBsAg reactive and HBV DNA reactive by commercial assay and 48 without HBV markers) and submitted to two in-house real ...
Tópico(s): Viral gastroenteritis research and epidemiology
2018 - Elsevier BV | Journal of Virological Methods
Produção Nacional
Revisado por pares
Vanessa Denardi Antoniassi Baldissera, Sônia Maria Villela Bueno,
doi: 10.5216/ree.v12i4.8830Neste estudo, centrado na sexualidade de idosas, objetivou-se desenvolver e avaliar estratégias de educação para a saúde baseada na pedagogia crítico-social, partindo da representação social da sexualidade pelas mulheres portadoras de Hipertensão Arterial Sistêmica, participantes de um grupo de encontro de um centro de saúde no noroeste do Estado do Paraná/Brasil. Tratou-se de uma pesquisa-ação, realizada no segundo semestre de 2009. A população-alvo foram seis hipertensas ...
Tópico(s): Cultural, Media, and Literary Studies
2010 - UNIVERSIDADE FEDERAL DE GOIÁS | Revista Eletrônica de Enfermagem
Produção Nacional
Revisado por pares
Luciane Almeida Amado Leon, Adílson José de Almeida, Vanessa Salete de Paula, Renata Santos Tourinho, Daniel Antunes Maciel Villela, Ana Gaspar, Lia Laura Lewis‐Ximenez, Marcelo Alves Pinto,
Despite the increasing numbers of studies investigating hepatitis A diagnostic through saliva, the frequency and the pattern of hepatitis A virus (HAV) markers in this fluid still remains unknown. To address this issue, we carried on a longitudinal study to examine the kinetics of HAV markers in saliva, in comparison with serum samples. The present study followed-up ten patients with acute hepatitis A infection during 180 days post diagnosis (dpd). Total anti-HAV was detected in paired serum and saliva ...
Tópico(s): Liver Disease and Transplantation
2015 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
B.L.C. Marques, Márcia Paschoal do Espírito-Santo, Vanessa Alves Marques, Juliana Custódio Miguel, Elisangela Ferreira da Silva, Cristiane Alves Villela‐Nogueira, Lia Laura Lewis‐Ximenez, Elisabeth Lampe, Lívia Melo Villar,
Dried blood spots (DBS) could be an excellent alternative for HCV diagnosis, since it is less invasive and can be stored and transported without refrigeration.The aim of this study was to optimize quantitative and qualitative methods for HCV detection in DBS.DBS and serum samples were collected from 99 subjects (59 anti-HCV/HCV RNA positive and 40 seronegative samples). Seven extraction methods and different PCR parameters were evaluated in DBS samples in the quantitative RT-PCR (qRT-PCR) developed ...
Tópico(s): HIV/AIDS drug development and treatment
2016 - Elsevier BV | Journal of Clinical Virology
Carlos Eduardo da Silveira Bueno, Marcos de Azevêdo Rios, Marcelo Santos Coelho, Alexandre Mascarenhas Villela, Alexandre Sigrist De Martin, A. Kato, Vanessa de Oliveira Alves, Rodrigo Sanches Cunha,
Objective: This study evaluates the efficacy of passive ultrasonic irrigation (PUI) in removing root canal filling material from endodontically treated teeth after using one of two reciprocating systems, Reciproc (VDW, Munich, Germany) or WaveOne (Dentsply Maillefer, Ballaigues, Switzerland), or one nickel-titanium (NiTi) rotary system, ProTaper Universal Retreatment (Dentsply Maillefer).Methods: One hundred and twenty straight root canals of extracted human maxillary incisors were instrumented and then ...
Tópico(s): Dental Radiography and Imaging
2017 - | European Endodontic Journal
Produção Nacional
Revisado por pares
Ana Carolina Campi‐Azevedo, Christiane Costa-Pereira, Lis Ribeiro do Valle Antonelli, Cristina Toscano Fonseca, Andréa Teixeira‐Carvalho, Gabriela Villela-Rezende, Raiany A. Santos, Maurício Azevedo Batista, Fernanda M.F. Campos, Luiza Pacheco-Porto, Otoni A Melo Júnior, Débora MSH Hossell, Jordana Grazziela Coelho-dos-Reis, Vanessa Peruhype-Magalhães, Matheus Fernandes Costa-Silva, Jaquelline Germano de Oliveira, Roberto Farias, Tatiana Guimarães de Noronha, Jandira Aparecida Lemos, Vanessa dos Reis von Doellinger, Marisol Simões, Mirian M de Souza, Luiz CC Malaquias, Harold Richard Persi, Jorge Marcelo Pereira, José A Martins, Marcos Dornelas-Ribeiro, Aline de A Vinhas, Tatiane R Alves, Maria de Lourdes de Sousa Maia, Marcos da Silva Freire, Reinaldo de Menezes Martins, Akira Homma, Alessandro Romano, Carla Magda Allan Santos Domingues, Pedro Luíz Tauil, Pedro Fernando da Costa Vasconcelos, María Rios, Iramaya Rodrigues Caldas, Luiz Antônio Bastos Camacho, Olindo Assis Martins‐Filho,
A single vaccination of Yellow Fever vaccines is believed to confer life-long protection. In this study, results of vaccinees who received a single dose of 17DD-YF immunization followed over 10 y challenge this premise. YF-neutralizing antibodies, subsets of memory T and B cells as well as cytokine-producing lymphocytes were evaluated in groups of adults before (NVday0) and after (PVday30-45, PVyear1-4, PVyear5-9, PVyear10-11, PVyear12-13) 17DD-YF primary vaccination. YF-neutralizing antibodies decrease ...
Tópico(s): Viral Infections and Vectors
2015 - Taylor & Francis | Human Vaccines & Immunotherapeutics
Produção Nacional
Revisado por pares
Vanessa Nogueira Soares, Sabry G. Elias, Gizele Ingrid Gadotti, Adriel E. Garay, Francisco Amaral Villela,
Currently, the standard germination test (SGT) is the official test for evaluating seed viability in seed testing laboratories around the world. The SGT takes 3 to 4 wk to complete for most grasses, including the dormancy breaking treatment period. The tetrazolium test (TZT), however, offers quick viability determination within 24 to 48 h, even for dormant seeds. This study was conducted to compare SGT and TZT results for tall fescue (TF), annual and perennial ryegrass (ARG and PRG), orchardgrass (OG), ...
Tópico(s): Plant and fungal interactions
2016 - Wiley | Crop Science
Produção Nacional
Revisado por pares
Ronaldo C. Araújo, Marcelo A. Mori, Vanessa F. Merino, Jean‐Loup Bascands, Joost P. Schanstra, Ricardo de Lima Zollner, Conceição A. Villela, Clóvis R. Nakaie, Antonio C.M. Paiva, Jorge L. Pesquero, Michael Bäder, João Bosco Pesquero,
Abstract Kinins are potent vasoactive peptides generated in blood and tissues by the kallikrein serine proteases. Two distinct kinin receptors have been described, one constitutive (subtype B 2 ) and one inducible (subtype B 1 ), and many physiological functions have been attributed to these receptors, including glucose homeostasis and control of vascular permeability. In this study we show that mice lacking the kinin B 1 receptor (B 1 -/- mice) have lower fasting plasma glucose concentrations but exhibit higher ...
Tópico(s): Adenosine and Purinergic Signaling
2006 - De Gruyter | Biological Chemistry
Produção Nacional
Revisado por pares
Ruan C. B. Ribeiro, Daniel B. de Marins, Iris Di Leo, Luana da Silva Gomes, Matheus G de Moraes, Bruno Lopes Abbadi, Anne Drumond Villela, Wellington F. da Silva, Luiz Cláudio Rodrigues Pereira da Silva, Pablo Machado, Cristiano Valim Bizarro, Luiz Augusto Basso, Marcela Cristina de Moraes, Vı́tor F. Ferreira, Fernando de Carvalho da Silva, Vanessa Nascimento,
Tuberculosis (TB) is one of the most fatal diseases and is responsible for the infection of millions of people around the world. Most recently, scientific frontiers have been engaged to develop new drugs that can overcome drug-resistant TB. Following this direction, using a designed scaffold based on the combination of two separate pharmacophoric groups, a series of menadione-derived selenoesters was developed with good yields. All products were evaluated for their in vitro activity against Mycobacterium ...
Tópico(s): Organoselenium and organotellurium chemistry
2020 - Elsevier BV | European Journal of Medicinal Chemistry