Gordana Švonja Parezanović, Mladena Lalić‐Popović, Svetlana Goločorbin-Kon, Velibor Vasović, Boris Milijašević, Hani Al‐Salami, Momir Mikov,
Tópico(s): Analytical chemistry methods development
2019 - Springer Science+Business Media | Archives of Environmental Contamination and Toxicology
Mladena Lalić‐Popović, Velibor Vasović, Boris Milijašević, Svetlana Goločorbin-Kon, Hani Al‐Salami, Momir Mikov,
Major problem for diabetic patients represents damage of blood vessels and the oxidative stress of the brain cells due to increased concentration of free radicals and poor nutrition of brain cells. Gliclazide has antioxidative properties and poor blood brain barrier (BBB) penetration. Bile acids are known for their hypoglycemic effect and as promoters of drug penetration across biological membranes. Accordingly, the aim of this study is to investigate whether the bile acid (deoxycholic acid) can change ...
Tópico(s): Protein Interaction Studies and Fluorescence Analysis
2013 - Hindawi Publishing Corporation | Journal of Diabetes Research
Ivana Vapa, Vukosava Milic Torres, Aleksandar Djordjević, Velibor Vasović, Branislava Srđenović Čonić, Viktorija Dragojević-Simić, Jovan Popović,
Tópico(s): Polymer Nanocomposite Synthesis and Irradiation
2012 - Adis, Springer Healthcare | European Journal of Drug Metabolism and Pharmacokinetics
Aleksandar Rašković, Nebojša Stilinović, Jovanka Kolarović, Velibor Vasović, Saša Vukmirović, Momir Mikov,
Silymarin is a complex of five major compounds, and silibinin is the most biologically active component of the complex. The aim of this study was to investigate, evaluate and confirm the potential cardioprotective and hepatoprotective effects of administration of silymarin, rich in silibinin, at a dose of 60 mg/kg orally for a time-span of 12 days on doxorubicin induced toxicity in male Wistar rats. The in vivo model was used to explore whether silymarin could prevent damage of liver and heart tissue ...
Tópico(s): Poisoning and overdose treatments
2011 - Multidisciplinary Digital Publishing Institute | Molecules
Vlada Cekic, Velibor Vasović, Vida Jakovljevič, Momir Mikov, Ana Sabo,
Th e aim of this study was to investigate infl uence of the preparation based on barley and brewer' s yeast extracts with chromium (BBCr) and stevioside (S) on fasting glycaemia and glycaemia in mice after glucose, adrenalin and alloxan application.Th e animals were divided into three groups: glucose mgkg - (I); adrenalin . mgkg - (II) and alloxan mg kg - (III) and into subgroups according to the substance they received: stevioside mg kg - (I-S, II-S, III-S); BBCr mg kg - (I-BBCr, II-BBCr, III-BBCr) and saline ml/ ...
Tópico(s): Biochemical effects in animals
2011 - Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina | Bosnian Journal of Basic Medical Sciences
Branislava Srđenović Čonić, Vukosava Milic Torres, Nevena Grujić, Karmen Stankov, Aleksandar Djordjević, Velibor Vasović,
Clinical use of doxorubicin continues to be challenged by its undesirable systematic toxicity, caused mainly by oxidative stress. The aim of this study was to investigate the effectiveness of fullerenol C60(OH)24 polyanion nanoparticles, an antioxidant agent, against doxorubicin-induced nephro-, testicular, and pulmonary toxicity. Results obtained in vitro suggest that fullerenol’s anti-proliferative property and protective effect against doxorubicin cytotoxicity are mediated by the antioxidative ...
Tópico(s): Carbon Nanotubes in Composites
2010 - Taylor & Francis | Toxicology Mechanisms and Methods
Aleksandar Rašković, Momir Mikov, Ranko Škrbić, Vida Jakovljevič, Velibor Vasović, Mihalj Poša, Ksenlia Kuhajda, S. Kevrešan, Z. Tomić, Djendji Siladji,
Tópico(s): Regulation of Appetite and Obesity
2008 - Adis, Springer Healthcare | European Journal of Drug Metabolism and Pharmacokinetics
Z. Tomić, Boris Milijašević, Ana Sabo, Dušan Lalošević, Vida Jakovljevič, Momir Mikov, Satman Majda, Velibor Vasović,
Tópico(s): Pharmacogenetics and Drug Metabolism
2008 - Adis, Springer Healthcare | European Journal of Drug Metabolism and Pharmacokinetics
Velibor Vasović, Saša Vukmirović, Mihalj Poša, Momir Mikov, Aleksandar Rašković, Vida Jakovljevič,
Tópico(s): Pharmacological Effects and Assays
2006 - Adis, Springer Healthcare | European Journal of Drug Metabolism and Pharmacokinetics
Ivana Ičević, Saša Vukmirović, Branislava Srđenović Čonić, Jan Sudji, Aleksandar Djordjević, Rade Injac, Velibor Vasović,
Polyhydroxylated, water soluble, fullerenol C60(OH)24 nano particles (FNP) in vitro and in vivo models, showed an expressive biological activity. The goal of this work was to investigate the potential protective effects of orally applied FNP on rats after a single dose of doxorubicin (DOX) (8 mg/kg (i.p.)) 6 h after the last application of FNP. After the last drug administration, the rats were sacrificed, and the blood and tissues were taken for the analysis. Biochemical and pathological results obtained ...
Tópico(s): Graphene and Nanomaterials Applications
2011 - Association of Chemical Engineers of Serbia | Hemijska industrija
Velibor Vasović, B Banić, Vida Jakovljevič, Z. Tomić, Vukica Milic-Djordjevic,
Tópico(s): Neuroscience and Neuropharmacology Research
2008 - Adis, Springer Healthcare | European Journal of Drug Metabolism and Pharmacokinetics
Vesna Jaćević, Vukosava Milic Torres, Viktorija Dragojević-Simić, Nataša Radić, Biljana Govedarica, Silva Dobrić, Branislava Srđenović Čonić, Rade Injac, Aleksandar Djordjević, Velibor Vasović,
Tópico(s): Boron and Carbon Nanomaterials Research
2007 - Elsevier BV | Toxicology Letters
Sonja Medic-Pericevic, Ivan Mikov, Mirjana Glavaski-Kraljevic, Milorad Španović, Andrea Božić, Velibor Vasović, Mikov Momir,
BACKGROUND: Professional drivers are part of the active working population, so there is a need for continuous improvement of operating efficiency and safety in driving. Reaction time is a very important driver's trait. OBJECTIVE: The aim of this stud
Tópico(s): Urban Transport and Accessibility
2020 - IOS Press | Work
Jovana Trifunović, Vladan Borčić, Saša Vukmirović, Velibor Vasović, Momir Mikov,
Purpose: Animal tests have been often used in toxicology to determine parameters describing toxicity of a particular substance. However, in vivo tests must fulfill ethical requirements, and are both time and money consuming. Therefore, computational methods are considered to be very useful in toxicity prediction. Methods: Retention parameters were acquired by normal-phase TLC. Lipophilicity was used as a key parameter for predicting toxic potential. The correlation coefficients between calculated ...
Tópico(s): Drug-Induced Hepatotoxicity and Protection
2016 - Taylor & Francis | Drug and Chemical Toxicology
Ivan Mikov, Velibor Vasović, Aleksandra Mikov, Svetlana Goločorbin-Kon, Karmen Stankov, Momir Mikov,
Herbicide 2,4-dichlorophenoxyacetic acid (2,4-D), a synthetic auxin which promotes uncontrolled plant growth is widely used. The aim of our study was to investigate, using an experimental model, the effect of herbicide 2,4-D on liver function tests, enzyme a amylase and glucose blood level. BALB/C mice were treated i.p. with the herbicide (30 mg/ kg 2,4-D) for four consecutive days. Twenty-four hours after the last injection, the treated and the control animals were weighed and sacrificed for biochemical ...
Tópico(s): Biochemical Acid Research Studies
2010 - Institute of Pesticides and Environmental Protection | Pesticidi i fitomedicina
Andrea Božić, Djordje Gajdobranski, Branislava Brestovački-Svitlica, Sonja Medic-Pericevic, Momir Mikov, Velibor Vasović, Ivan Mikov,
The presence of low back pain in nurses is becoming increasingly prominent and it has significant impact both on the individual as well as on the community.The aim of this study was to determine the prevalence of low back pain among practicing nurses.The research has been conducted in five health care institutions in the area of Vojvodina. Data were collected using the Nordic Musculoskeletal Questionnaire (NMQ).Five hundred and twelve nurses participated in this study. Most of the participants (93. ...
Tópico(s): Ergonomics and Musculoskeletal Disorders
2021 - IOS Press | Work
V. Jakovljević, Ana Sabo, Z. Tomić, Boris Milijašević, Milica Popović, Velibor Vasović, Aleksandar Rašković,
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2009 - Adis, Springer Healthcare | European Journal of Drug Metabolism and Pharmacokinetics
Velibor Vasović, Aleksandar Rašković, Momir Mikov, Ivan Mikov, Boris Milijašević, Saša Vukmirović, Zorana Budakov,
Stevioside is a glycoside that supposedly possesses a number of pharmacodynamic effects such as anti-infective, hypoglycemic, along with the beneficial influence on the cardiovascular system. The aim of this study was to determine the effect of rats pretreatment with aqueous solution of stevioside on pharmacological actions of adrenaline, metoprolol and verapamil.Rats were administered (intraperitoneally 200 mg/kg/day) stevioside as aqueous solution or physiological saline in the course of 5 days, ...
Tópico(s): Phytochemicals and Antioxidant Activities
2014 - Military Health Department, Ministry of Defance, Serbia | Vojnosanitetski pregled
Velibor Vasović, Saša Vukmirović, Momir Mikov, Ivan Mikov, Zorana Budakov, Nebojša Stilinović, Boris Milijašević,
It is known that bile acids improve the absorption, bioavailability and pharmacodynamic characteristics of some drugs. Morphine analgesia is produced by activation of opioid receptors within the central nervous system (CNS) at both spinal and supraspinal levels. Since a morphine molecule contains 3 polar groups and therefore hard to transfer through the blood-brain barrier, the aim of the study was to examine the potential influence of bile acids derivates, namely sodium salt of monoketocholic acid ( ...
Tópico(s): Neuropeptides and Animal Physiology
2014 - Military Health Department, Ministry of Defance, Serbia | Vojnosanitetski pregled
Velibor Vasović, B Banić, Vida Jakovljevič,
We studied the effect of caffeine on the transport of quinidine through the blood-brain barrier (BBB) to the central nervous system (CNS) in rats. The anesthetized animals received quinidine in the form of a retrograde intra-arterial bolus injection (15 s) into the right axillary artery 30 min after receiving a subcutaneous injection of caffeine (test group) or physiological solution (control group). Rats were decapitated at 30, 60, 90, 120, and 240 s after quinidine administration. Blood samples were ...
Tópico(s): Advanced MRI Techniques and Applications
2007 - De Gruyter | Journal of Basic and Clinical Physiology and Pharmacology
Radojka Jokšić-Mazinjanin, Nikolina Marić, Aleksandar Đuričin, Zoran Gojković, Velibor Vasović, Goran Rakić, Milena Jokšić-Zelić, Siniša Saravolac,
Introduction: Trauma scoring systems in prehospital settings are supposed to ensure the most appropriate in-hospital treatment of the injured. Aim of the study: To determine the sensitivity and specificity of the CRAMS scale (circulation, respiration, abdomen, motor and speech), RTS score (revised trauma score), MGAP (mechanism, Glasgow Coma Scale, age, arterial pressure) and GAP (Glasgow Coma Scale, age, arterial pressure) scoring systems in prehospital settings in order to evaluate trauma severity ...
Tópico(s): Abdominal Trauma and Injuries
2023 - Multidisciplinary Digital Publishing Institute | Medicina
Mladena Lalić‐Popović, Jovana Paunković, Zorica Grujić, Svetlana Goločorbin-Kon, Velibor Vasović, Hani Al‐Salami, Momir Mikov,
Tópico(s): Electrolyte and hormonal disorders
2016 - Elsevier BV | Placenta
Vlada Cekic, Velibor Vasović, Vida Jakovljevič, Dušan Lalošević, Ivan Čapo, Momir Mikov, Ana Sabo,
In the recent years, herbal preparations have been more used to treat diabetes. Dietetic supplement based on barley and beer yeast enriched with chromium (BBCr) is registered in Serbia as a supplement in the treatment of type 2 diabetes.To investigate the effect of the preparation based on barley and brewer's yeast with chromium (BBCr), rosiglitazone (R) and their combination (BBCr+R) on fasting glycaemia and glycaemia in mice after glucose, adrenalin and alloxan application.The animals were divided ...
Tópico(s): Fungal Biology and Applications
2011 - Serbian Medical Society | Srpski arhiv za celokupno lekarstvo
Velibor Vasović, Saša Vukmirović, M Pjević, Ivan Mikov, Momir Mikov, V. Jakovljević,
Tópico(s): Drug-Induced Hepatotoxicity and Protection
2010 - Adis, Springer Healthcare | European Journal of Drug Metabolism and Pharmacokinetics
Zoran Gojković, Radojka Jokšić-Mazinjanin, Velibor Vasović, Gordana Smieško, Predrag Šaponja, Radmila Petrović, Milena Jokšić-Zelić, Siniša Saravolac, Momir Mikov,
Context: Severe trauma is a leading cause of mortality and high-degree invalidity. Emergency Medical Services (EMS) are usually first-line responders to the traumatized persons and the management of traumatism and its dynamics depend on the accurate evaluation by the EMS providers. In order to evaluate the severity of injury, it is necessary to use the adequate trauma score (TS). The aim of this paper is to compare the most common prehospital scoring system RTS (Revised TS) with newly developed MGAP ( ...
Tópico(s): Abdominal Trauma and Injuries
2019 - | Timocki medicinski glasnik
Boris Dojčinović, Nada Banjac, Saša Vukmirović, Tamara Dojčinović, Lucija Vasović, Dalibor Mihajlovic, Velibor Vasović,
Background and Objectives: PoCUS ultrasound applications are widely used in everyday work, especially in the field of emergency medicine. The main goal of this research was to create a diagnostic and therapeutic protocol that will integrate ultrasound examination of the lungs, ultrasound measurements of the inferior vena cava (assessment of central venous pressure) and BREST scores (risk stratification for heart failure), with the aim of establishing a more effective differential diagnostic approach ...
Tópico(s): Radiation Dose and Imaging
2024 - Multidisciplinary Digital Publishing Institute | Medicina
Teodora Krstić, Milovan Radulović, Nikolina Marić, Aleksandar Djuricin, Milena Jokšić-Zelić, Velibor Vasović, Aleksandra Petrić, Simeon Latinović, Radojka Jokšić-Mazinjanin,
Tópico(s): Cardiac pacing and defibrillation studies
2025 - Faculty of Agronomy in Čačak | ABC casopis urgentne medicine
Dalibor Mihajlović, Đorđe Đukanović, Milica Gajić Bojić, Sanja Jovičić, Nebojša Mandić-Kovačević, Snežana Uletilović, Žana Maksimović, Nebojša Pavlović, Boris Dojčinović, Sergey Bolevich, Momir Mikov, Ranko Škrbić, Nada Banjac, Velibor Vasović,
Patients suffering from cholelithiasis have an increased risk of developing cardiovascular complications, particularly ischemic myocardial disease. Ursodeoxycholic acid (UDCA), already used in clinical practice for the treatment of cholelithiasis and related conditions, has proven antioxidative, anti-inflammatory, and cytoprotective effects. Therefore, the aim of this study was to investigate the cardioprotective effect of UDCA pre-treatment on isoprenaline-induced myocardial injury in rats. Male ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2024 - Multidisciplinary Digital Publishing Institute | Biomolecules
Nada Banjac, Velibor Vasović, Nebojša Stilinović, Ana Tomás, Lucija Vasović, Nikola Martić, Dušan Prodanović, Vladimir Jakovljević,
Prof [...]
Tópico(s): Hormonal Regulation and Hypertension
2024 - Multidisciplinary Digital Publishing Institute | Pharmaceuticals
Nada Banjac, Velibor Vasović, Nebojša Stilinović, Ana Tomás, Lucija Vasović, Nikola Martić, Dušan Prodanović, Vladimir Jakovljević,
The dose-response relationship of sildenafil effects on cardiac function is not completely elucidated. The aim of this study was to assess the effects of different doses of sildenafil on coronary flow and oxidative stress in isolated rat hearts. Coronary flow and markers of oxidative stress, including nitrite outflow, and superoxide anion production in coronary effluent, were determined for isolated rat hearts. The experiments were performed during control conditions and in the presence of sildenafil ( ...
Tópico(s): Cardiac Arrhythmias and Treatments
2023 - Multidisciplinary Digital Publishing Institute | Pharmaceuticals