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Artigo Revisado por pares

J. B. Ward-Perkins, Leslie Murray Threipland, Mario Torelli,

... property belonging to Sig. O. Baldi on the Via di S. Cornelia about 1·5 km. north of the ancient ...

Tópico(s): Ancient Mediterranean Archaeology and History

1970 - Cambridge University Press | Papers of the British School at Rome

Jornais Acesso aberto

Roger Bannister, J. J. R. Trethowan, Elizabeth Nicholas, Harold Hobson, Peter Fleming, Kenneth Pearson, Nicholas Carroll The Sunday Times Diplomatic Correspondent, James Weatherhead, J. W. Lambert, Daniel George, Professor Alan S. C. Ross, Dorothy McCall, Alan Parry, Cyril Beaumont, (Rev.) H. Glyn Lewis, John Russell, Derek Prouse, Vivian Jenkins, Tom Margerison, Theo. A. Stephens, John Sellers, N. M. Howgrave-Graham, Cyril Connolly, Ian Fleming, A. W. G. Harley, Sir Herbert Thompson, Alex Comfort, Raymond Mortimer, Siriol Hugh Jones, Ernest Newman, Thomas Gray, Fougasse, Henry Brandon Representative of The Sunday Times, G. H. Derrington, Charles H. Willi, Roger Mortimer, William Fish The Sunday Times Representative, Norman Crump The Sunday Times City Editor, Antony Terry Representative of The Sunday Times, (Mme) Marian Deschamps, Lord Vansittart, Ernestine Carter, Michael Hadley, P. J. Hall, A. H. Russell Past-President, R. L. Hollands, R. C. Robertson-Glasgow, J. W. Davis, Felix Aprahamian, Paul Hogarth The Sunday Times Special Representative, Stephen Coulter The Sunday Times Representative, Robert Robinson, Henry Longhurst, L. Lewis, H. G. Vevers, John Metcalf, Sir Robert C. K. Ensor, Iain Lang, Roy Pascal, Ritchie McEwen Special Representative of The Sunday Times, C. H. O'd. Alexander, George Schwartz, Maurice Wiggin, Atticus, G. de la Condamine, Harvard Mentana, Gordon Ross, The Rev. G. W. Butterworth Litt. D., Richard Findlater, J. B. Slade-Baker Special Representative of The Sunday Times, D. W. Brogan, George Willesden, Susan Cooper, Fred Maynard, Hessa George, Kenneth Konstam, Molly Cochrane, Israel Shachter,

... James Barrie Christmas Cards Trials & Tribulations The Remarkable Cornelia Connelly The Case of Cornelia Connelly. By Juliana Wadharn. (Collins. 16s.) Mr. Nehru ...

1956 - Gale Group | Sunday Times HA GDA

Jornais Acesso aberto

Jonathan James-Moore, Michael Prescott, Steve Pittard, Margaret James, Matthew Wall, Mo Shapiro, Don Taylor, C Thibaut, John Follain, Barbara Hall, Frank Parker, Daniela Paudice, J B, Christine McGourty, Francois Pienaar, Fred Redwood, Carole Dawson, Aady Knott, Jon Swain, John Perter, James Clark, Nicholas Rufford, John Peter, Pam Barrett, Jan Ladbrooke, Amanda Ursell, Emma Moore, Lorraine Harvey, Miranda Innes, Lance Jenkins, John Jay, J D, Sally Thomson, Frank Whitford, Ivo Tennant, Martin Butler, M Bibal, Sam Gilpin, Sally O'Reilly, Tanya, David Smith, Graham Henry, Richard Bond, caroline Donald, Melanie Phillips, Nick Pitt, Neil Wormald, E P, Andrew Sullivan, Dave Ferris, Clive Davis, Preston King, Mary Wilson, Sarah Keighley, Hywel Williams, Ella, Clive Woodward, William Brittain, Tony Allen-Mills, Martin James, Isabella Blow, John Gardner, Tom Walker, Anthony Sattin, Robert Winnett, Nick Gardber, Irwin Stelzer, Charles Nicholl, Tom English, Robert Hewison, Peter Wilson, Roger Anderson, Simon Fanshawe, Lawrence Dallaglio, David Dougill, York Membery, John Mortimer, John Evans, Philip Kingsley, Cathy Cooper, Sue Clayton, David Hewson, J Alexander, Tania Alexander, Cath Sylvester, Cary L Cooper, Margaret Coles, Hugh Canning, Alasdair Reid, Hugh Mcllvanney, Margarette Driscoll, Martin Davies, Jeremy Clarkson, Peter Watson, Nigel Williams, Dorothy Andrew, Christine Stopp, Louise Taylor, John Waples Deputy City Editor, Edward Porter, Max Anderson, Stewart Lee, Peter Kemp, K E Mawardy, Eben Black, Nick Newman's, Brian Rowe, Lynne Wallis, Graham, Tony Misiolek, Phil Craigie, Adam Nathan, James Bailey, Phil Greening, Nick Gardner, Robert Howlett, Phillip Oppenheim, Stuart Wavell, Stella Bingham, Josephine Smit, Alastair Hendy, Neil Back, Sir Richard Sykes, Clive Jacobs, Lisa Jardine, Simon Mills, Cosmo Landerson, James Clark Home Affairs Correspondent, Smita Talati, Paul Driver, Paul Bray, Malcolm Farrow, Gillian Taylforth, John Humphrys, Andrew Hagley, Maeve Sheehan, Nicholas Hellen, Peter Windsor, Richard Brooks, Ian Hawkey, David Thomas, Steve, Christopher Morgan, Rob Lane editor, Shelley Von Strunckel, Tim Rayment, Brian Jackman, Geoffrey Holmes, Antonella Lazzeri, Sue Beenstock, Mark Edwards, Duncan Lawson, Sarah Gracie, Susan Clark, Ken Livingstone, Mark Austin, David Lawrenson, Eben Black Chief Political Correspondent, Liz Reld, Matt Dawson, Rose, Danny O'Brien, T W, Jennifer Asiama, Alan Combes, Sue Reid, Raymond Keene, Senay Boztas, Zoe Brennan, Cosmo Landesman, Diana Wright, Kipper Williams, S N, David Orr, Chris Partridge, Stephen Jones, Richard Evans, Peta Bee, Melanie Philips, Arnaud Bani, Bill Turque, M J, Gary Buchanan, Rob Ryan, Dr John Greensmith, Claire Oldfield, David Walsh, Trevor Lewis, Jack Grimston, S P, Bryan Appleyard, Lois Rogers Medical Correspondent, Colin McDowell, Stephen Armstrong, F C, Ron Clarke, Christopher Goodwin, Josh Salzmann, Bethan Cole, Mark Prigg, Victoria O'brien, Roland White, Garth Alexander, Robert Henderson, Kim Fletcher, David Young, Maurice Chittenden, Alex Fortune, Kevin Pratt, Richard Brooks Arts Editor, Richard Rae, Mark Franchetti, Jonathan Powell, Ray Hutton, Jon Ungoed-Thomas, Andrew Oakes, Andrew Rogers, Michele Kirsch, Deborah Williams, Jonathan Leake, S J, John Crossland, Michael Sheridan, Christine Webb, Alison Steed, Godfrey Smith, Wendy Worviell, Jacqueline Champ, Camp Beaumont, Hilary Lowe, Trevor Rees-Jones, John Waples, Jeremy Hart, Hunter Davies, A A Gill, Anna Selby, Matthew Campbell, Brian Glanville, Anthony Croft, Tom Robbins, Stephen Pettitt, Jonathan Leake Science Editor, Karen MacGregor, Jeremy Langmead, R H, Eric McGraw, Andrew Lorenz, Sally Kinnes, Naomi Caine, Hazel Courteney, Nicholas Hellen Media Editor, David Wickers, Silvia Rodgers, Roger Dobson, Tom Rhodes, John Chambers, Len Tyler, John Aizlewood, Mrs J Hughes, Emma Penn, Mark Hodson, Graham Norwood, Joe Lovejoy, Jonathan Futrell, Mark Porter, Rupert Steiner, David Parstey, Dan Cairns, David Grylls, David Parsley, Allan Hall, Thomas Gilchrist, Brian Alexis, Claire Burston, David Smith Economics Editor, Ken Ellis, Mrs D Brooker, Simon Crerar, Anthony Howard, Helen Vandevelde, Martin Booth, Bob Dwyer, Walter Ellis, Joanna Simon, India Knight, Stephen Peters, Steve Grant, Simon Howard, Danny Danziger, Dan Pearson, Lisa Verrico, Dominic Rushe, Boris Schapiro, Karen Robinson,

... 7824 8787. Burgundy checked sfcarf, from £30, by Cornelia James, 45 Maddox Street, W1; inquiries: 020 7499 ...

2000 - Gale Group | Sunday Times HA GDA

Revisão Acesso aberto Revisado por pares

Cornelia Amălinei, Ioana Păvăleanu, Ludmila Lozneanu, Raluca Bălan, Simona Eliza Giușcă, Irina-Draga Căruntu,

Firstly described at the end of nineteenth century, endometriosis remains an enigmatic disease, from etio­pathogenesis to specific markers of diagnosis and its ability to associate with malignancies. Our review has been designed from a historical perspective and steps up to an updated understanding of the disease, facilitated by relatively recent molecular and genetic progresses. Although the histopathological diagnosis is relatively simple, the therapy is difficult or ineffective. Experimental ...

Tópico(s): Endometriosis Research and Treatment

2018 - Via Medica | Folia Histochemica et Cytobiologica

Jornais Acesso aberto

Jeremy Rundall, Hugo Young Social Services Correspondent, (Miss) C Hovenden, Maggie Angeloplon, Godfrey Hodgson, Terry Delaney, Charles Raw, Richard Buckle, James Margach, Oliver Stanley, Elizabeth Nicholas, Nicholas Carroll Diplomatic Correspondent, Brian Walkden, Harold Hobson, Paula Davies, Ian Peebles, James Hadley, Desmond Zwar, John Morgan, Francis Wyndham, Kay Dick, John Leech, Bute Hewes, John Moon, Antony Terry, Roger Nuttall, R Postill, Peter Elstob, Frederic Raphael, Elizabeth Good, J R Barnard, Henry Brandon, John Russell, D. H Tilley, David Divine, Linda Blandford, Alan E T Barcock, Max Marquis, Ben Wright, Mr C. O'Leary, Philip Clarke, Derek Jewell, Patrick Campbell, Vivian Jenkins, Harold Horstmeyer, Murray Sayle, Rev. Dr. Ceell Northcott, Peter Willett, Peter Forster, Bryan Silcock Science Correspondent, Gordon Hamilton, Robin Marlar, Robert Troop, John Bunyan Director, Malcolm Southan, Dan van der Vat, Hugh Somerville, Cyril Connolly, Anthony J. W. Vaughan, Anthony Vice, Colin Chapman Education Correspondent, Brian Crozier, Raymond Mortimer, David Holden, Maxwell Boyd, Evelyn Irons, Anthony Storr, Valerie Pitt, Peter Wilsher, Susan Noel, Roger Mortimer, Alan McELWAIN, Desmond Shawe-Taylor, Stephen Coulter, Sydney Lenssen, David Tribe President, Gwen Nuttall, Stephen Aris, O S Swainson, Lanning Roper, Dilys Powell, Brigid Keenan, Harold H. Godwinson, David Wiggins, Harold Abrahams, Felix Aprahamian, W G Hayter, Maurice Cranston, J Z Arblaster, Michael Ratcliffe, Ian Coulter Industrial Correspondent, Henry Longhurst, James Margach Political Correspondent, Hunter Davies, P. D., Peter Buckman, Brian Glanville, Richard West, Keith Richardson, Michael Green, C. H. O'd. Alexander, Raymond Brooks-Ward, Maurice Wiggin, Vernon Scannell, Norman Moss, Edgar A Mordecal, Gordon Ross, J R, Harlow Unger, J G Links, Wendy Jones, Pauline Peters, Michael Mott, Kenneth Konstam, Peter Blaker, John Mattison, Tom Shaw,

... H Gebhard, John H Gagnon, Wardell B Pomeroy, Cornelia V Christenson/Heinemann 5gns Meeting in Manchester For ... Masters/Secker & Warburg 30s That Awful Mess on via MERULANA/by Cario Emilio Gadda, translated by William ...

1966 - Gale Group | Sunday Times HA GDA

Carta Acesso aberto Revisado por pares

Umair Munawar, Leo Rasche, Nicole Müller, Cornelia Vogt, Matteo C. Da Vià, Larissa Haertle, Panagiota Arampatzi, Sascha Dietrich, M. Roth, Andoni Garitano-Trojaola, Maximilian Steinhardt, Susanne Strifler, Miguel Gallardo, Joaquín Martínez‐López, Ralf C. Bargou, Tobias Heckel, Hermann Einsele, Thorsten Stühmer, K. Martin Kortüm, Santiago Barrio,

TO THE EDITOR: Recently, biallelic (“double hit”) TP53 inactivation, occurring in 2% to 4% of newly diagnosed multiple myeloma (MM) patients, was identified as an ultimate high-risk feature of MM, being associated with median survival of <2 years.[1][1][⇓][2]-[3][3] We and others have shown

Tópico(s): Cancer Genomics and Diagnostics

2019 - Elsevier BV | Blood

Jornais Acesso aberto

Mr. Churchill, Philips Viscount Elveden, Kenneth Hare, J. H. T. Wharton, Gordon Sherry, Sir Ronald Storrs, L. R., T. Harding, W. R. A., Herbert Sidebotham, R. C., Doreen Wallace, J. P. Dickie, James Stephens, R. F. Bretherton, James Agate, Prince Chichibu, H. F. Crowther-Smith, Walter Crick, R. Boyd Robson, Desmond MacCarthy, J. Holt Wilson, Miss Penelope Dudley Ward, Iliffe's, Hamilton Price, Richard Gillbard, Miss Hardwick, Frederic Basedow, H. M. Abrahams, A. T. Johnson, O. M. Green, Mr. Oliver's, A. C., Geo. D. Trusler, Jessica Tandy, Richard Clowes, Basil Maine, H. J. H., Milward Kennedy, Lord Strathcona, D. R. Gent, Hockley Clarke, C. L., St. Dean Paul's, C. Willett Cunnington, Ruby A. White, Dennis P. Teichman, Pandora, H. F., N. C. W. Edge, S. C. Kaines Smith, Ernest Newman, Mr. Hore-Belisha, J. G. Noppen, Ralph Straus, Sir G. Gillett, J. N. D. La Touche, E. V. Lucas, Lord Dunsany, Muriel Beckwith, Sydney W. Carroll, C. A. Knapp, Edward Shanks, Dilys Powell, G. Richardson, Elton Ede, Mr. Noel Baker, Reginald Bennett, E. P., Edwin L. Lutyens, Bessborough, R. J. Barrett Financial Editor, Ashley Sampson, Herbert Wood, A. B., E. A. Taylor Vice-Admiral, B. Fitzgerald-Moore, Lorna Lancaster, Henry Longhurst, Hubert Winterbotham, C. V. O. M. P., Eleanor Rathbone, J. M. Bulloch, Kenneth Romney Towndrow, Mr. P. J. Chaplin's, J. D. A. Johnson, Atticus, Laurence Oliver, E. H. Blakeney, Mrs. Muriel P. Fairbrother, T. T. Barton, H. N. Ridley, Roland Bayley, Dr. Buchman, C. M. G.,

... Little Theatres "Black Limelight" Q Tuesday, April 13 Cornelia Otis Skinner Little Hamlet at Elsinore Plays and ... Sport Barkers Duodenal Ulcers Isle of Skye Esse Via Imperial Opera without Fears Broadcasting To-Day's ...

1937 - Gale Group | Sunday Times HA GDA

Revisão Acesso aberto Revisado por pares

Cornelia Frank, Sarah N. Kraeutner, Martina Rieger, Shaun G. Boe,

It is well accepted that repeatedly imagining oneself acting without any overt behavior can lead to learning. The prominent theory accounting for why imagery practice is effective, motor simulation theory, posits that imagined action and overt action are functionally equivalent, the exception being activation of the end effector. If, as motor simulation theory states, one can compile the goal, plan, motor program and outcome of an action during imagined action similar to overt action, then learning ...

Tópico(s): Motor Control and Adaptation

2023 - Springer Science+Business Media | Psychological Research

Jornais Acesso aberto

Julia Llewellyn Smith, Nigel Calder, Michael Furnam, Douglas Adams, Sally Brock, Allan Palmer, Professor Gideon Garter, Tony Pia, Amanda Ursell, Jonathan Miller, Sylvia Roger, Ferdinand Mount, Marc Rothman, Neil Wormald, Anthony Sattin, Rosie Millard, Dr Tubonye Harry, David Hewson, Hugh Canning, Susan Spaull, Andrew Stone, Sarah Dempster, Margaret Mitchell, Robert MacFariane, Lord Newby, Antonio Carluccio, Paris Hilton, Neil Back, Julian Rendell, John Humphrys, Christopher Morgan, Martin Johnson, Alicia Wyllie, Jan Baldwin, Sarah Gracie, Victoria Barnsley, Bernard Stay, Susan Greenfield, Francis Spufford, Charlie Dimmock, Rev Canon Michael Jarratt, Cornelia Funke, Diarmaid MacCulloch, Keith Cameron, Phil Thirlway, C Webley, Nick Hornby, St Andrews, Nick MacKinnon, John Elliott, Ali Allen, Maurice Chittenden, Roy Rich, Kenneth Grahame, Gary Firkins, Matthew Parris, Godfrey Smith, Marc Zakian, David Parsons, Ian Buruma, Matthew Campbell, Mary Braid, Nick Fielding, Simon Buckland, James Knight, Graham Norwood, John Harris, St James, David Budworth, William Lewis Business editor, Philip Pullman, Susannah Price, Charles Dickens, Sarah Baxter, Danny Danziger, Dan Pearson, Jason Dawe, Monsieur Mangetout, Hala Jaber, Matthew Wall, Sebastian Faulks, Pauline van Lynden, Peter Whitfield, Peter Whittle, Hamish Stevenson, Andrew Longmore, Aidan Hartley, A A Milne, Peter Shortell, Jamie Graham, Jonny Wilkinson, Steven Poole, E P, T J, Leo Tolstoy, Matt Rudd, Anthony Bozza, Geraldine Hackett, Cally Law, David Bond, Louis de Bernières, Victoria Segal, Richard Wilson, Edward Porter, Phil Spencer, Anthony Peregrine, Eben Black, Martin Rees, Patrick Maxwell, Stuart Wavell, Paul Donovan, Antonio Damasio, David Charter, Hugh McIlvanney, Garth Pearce, Julie Earle-Levine, Sharon, Stuart Andrews, B C, David Leppard, Dan May, Gisela Stuart, John Brownlow, John Griffiths, Eben Black Chief Political Correspondent, Alan Combes, Reuven Paz, Gareth Huw Davies, David Cracknell, Katrina Manson, Diana Wright, Joy Millward, Jeff Ambler, Harry Sibley, Peter Koenig, Barry Flatman, Louisa May Alcott, Natalie Graham, David Walsh, Caroline Gascoigne, Jack Grimston, Danny South, Gordon Flight, Stephen Armstrong, Bethan Cole, Dr Anthony Cooper, Roger Panting, Richard Woods, Lyle Starritt, Ray Hutton, Charles Ziarko, Martin Coath, John Crossland, David Starkey, Alan Smith, A A Gill, Tennent, Brian Glanville, Michael Morgan, Daphne du Maurier, Barry Keenan, Dr Beverly Malone, Nigel Powell, Brian Doogan, Ben Dowell, Clifford Bishop, John Cornwell, Tina Cook, Eugene Trivizas, Hugh Pearman, Mick Hall, J Randy Taraborrelli, Gerard Connolly, A Stephenson, Jason Robinson, John Dugdale, David Dimbleby, Barbara Hall, Jon Swain, Nicholas Rufford, Rob Hughes, John Peter, Maggie Alderson, Susan d'Arcy, Josh Lewsey, Ivo Tennant, Matt Wolf, Gina Ford, David Smith, Philip Pangatos, Nick Pitt, Mick Jagger, Tobias Jones, Julian Barnes, Lawrence Dallaglio, Warren Shore, Charlie Watts, Alanna Nash, Jason Webster, Maria McEriane, Lindsay Baker, Peter Ackroyd, John O'Donnell, Chris Bryant, Sandy Balfour, Charlotte Brontë, Ben Reedy, Duncan Bennett, Sir Richard Branson, Jeremy Guscott, Diana Henry, Peter Miller, Vincent Crump, Paul Kimmage, C S Lewis, Chris Woodhead, Ben Wootliff, Tony Fearon, Mark Edwards, Rachel Bridge, Susan Clark, Stuart Miles, Ronnie Wood, Hugh Hamilton, Raymond Keene, Sandra Laverton, Marie Colvin, Tony Froggatt, Harper Lee, Stephen Jones, Stephen Bleach, Louise Armitstead, Nick Cain, Sophie Tweedale, Daisy Critchley, Anne Applebaum, R W Johnson, George Walden, Emily Brontë, Roland White, Richard M Fairclough, Victoria O'brien, Richard Rae, Jeff Green, Joanna Jepson, Jon Ungoed-Thomas, David Carpenter, Michael Sheridan, Jane Austen, Barry Collins, John Waples, Jonathan Calvert, J Rr Tolkien, Mark Hodson, Joe Lovejoy, Peter Lynch, Dan Cairns, Judith Flanders, Matt Ridley, David Smith Economics Editor, Helen Vandevelde, James Luckhurst, Chris Feetenby, Simon Howard, R B, Dominic Rushe, Mark Barrett, Steven Shukor, J K Rowling, Jane Cornwell, Joseph Heller, Alec Stewart, Alexander Hilton, Philip Norman, Helen Davies, Jennifer Donnelly, Terry Hope, Frank Whitford, Nicolette Jones, Sybil Kapoor, Kathryn Cooper, P D, Samantha Power, Frederic Raphael, Ko Samui, Andrew Porter, Tony Allen-Mills, Simon Wilde, Frank Blin, Robert Sandall, Robert Winnett, Irwin Stelzer, Robert Hewison, Peter Wilson, Maeve Creber, David Dougill, Frank Graham, Simon Switala, G Hughes, Jeremy Clarkson, David Cairns, Nick Middleton, Greg Struthers, Lucinda Bruce-Gardyne, George Perry, Lydia Slater, Paula Robinson, Nino Di Cara, Roger Eglin, Jasper Gerard, Derek Clements, Paul Driver, Kathryn Harrison, Ben Schott, Ian Hawkey, Paul Durman, Keith Richards, Jacqueline Parker, Christina Lamb, Bob Graham, Cosmo Landesman, Gordon Ramsay, Rosie Boycott, Anna Funder, Dominic O'Connell, Andrew Holgate, Caroline Donald, Liat Joshi, Colin McDowell, Ron Clarke, Auguste Racinet, Sylvie Simmons, Shane Watson, B Clay, Cindy Duffield, Emma Soames, Leah Hardy, B Meadows, Amanda Craig, John Harlow, Christopher Ricks, Ian MacDonald, Sally Kinnes, Naomi Caine, David Wickers, Peter Almond, Minette Marrin, Alistair Baker, Andrew Davidson, Paul Stephen Lubicz, Pete Oliver, Joanna Simon, Matthew Goodman, David Robertson, India Knight, J D Salinger, Robin Hobb, Tom Holland, Tom Norrington-Davies,

... Final Century Tomorrow's People Magic Universe Nature via Nurture Genes, Experience and What Makes Us Human ...

2003 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Cornelia Pechmann, Li Pan, Kevin Delucchi, Cynthia M. Lakon, Judith J. Prochaska,

Background: The medical field seeks to use social media to deliver health interventions, for example, to provide low-cost, self-directed, online self-help groups. However, engagement in online groups is often low and the informational content may be poor. Objective: The specific study aims were to explore if sending automessages to online self-help groups encouraged engagement and to see if overall or specific types of engagement related to abstinence. Methods: We conducted a Stage I Early Therapy ...

Tópico(s): Digital Mental Health Interventions

2015 - JMIR Publications | Journal of Medical Internet Research

Artigo Acesso aberto Revisado por pares

Cornelia H. Rinderknecht, Sujin Roh, Achal Pashine, Michael P. Belmares, Namrata S. Patil, Ning Lü, Phi Truong, Tieying Hou, Claudia Macaubas, Tae‐Jin Yoon, Nan Wang, Robert Busch, Elizabeth Mellins,

DM catalyses class II-associated invariant chain peptide (CLIP) release, edits the repertoire of peptides bound to major histocompatibility complex (MHC) class II molecules, affects class II structure, and thereby modulates binding of conformation-sensitive anti-class II antibodies. Here, we investigate the ability of DM to enhance the cell surface binding of monomorphic antibodies. We show that this enhancement reflects increases in cell surface class II expression and total cellular abundance, but ...

Tópico(s): Monoclonal and Polyclonal Antibodies Research

2010 - Wiley | Immunology

Artigo Acesso aberto Revisado por pares

Larissa Haertle, Santiago Barrio, Michal Šimíček, Umair Munawar, Ricardo Sánchez, Max Bittrich, Matteo C. Da Vià, Cornelia Vogt, Nicola Giesen, Andoni Garitano-Trojaola, Silvia Nerreter, Thorsten Stuehmer, Marc S. Raab, Joaquín Martínez‐López, Roman Hájek, Hermann Einsele, Leo Rasche, Thomas Haaf, K. Martin Kortüm,

Background: Various treatment regimen in multiple myeloma (MM) are based on proteasome inhibition (PI). Although effective at therapy start, most patients relapse and develop drug resistance over time. To better understand the molecular underpinnings associated with PI resistance, we studied genetic and epigenetic alterations of the 26S proteasome genes in PI exposed patients. Methods: We performed a meta-analysis comprised of M3P targeted sequencing datasets and other publicly available WGS/WES sets. ...

Tópico(s): Protein Degradation and Inhibitors

2019 - Elsevier BV | Blood

Carta Revisado por pares

Orlando Catalano,

... Correspondence Orlando Catalano, Radiology Unit, Istituto Diagnostico Varelli, via Cornelia dei Gracchi 65, Naples I-80126, Italy. Email: [ ... Correspondence Orlando Catalano, Radiology Unit, Istituto Diagnostico Varelli, via Cornelia dei Gracchi 65, Naples I-80126, Italy. Email: [ ...

Tópico(s): Heterotopic Ossification and Related Conditions

2023 - Wiley | Journal of Clinical Ultrasound

Artigo Revisado por pares

Daniel Obrecht, Cornelia Zumbrunn, Klaus Müller,

... 4]Oxazin-2-ones and α-Alkynyl Ketones via a Tandem Mukaiyama-Aldol Addition/Aza-Cope RearrangementDaniel Obrecht, Cornelia Zumbrunn, and Klaus MüllerView Author Information F. Hoffmann- ...

Tópico(s): Synthesis and Catalytic Reactions

1999 - American Chemical Society | The Journal of Organic Chemistry

Artigo Revisado por pares

James M. Reynolds,

... destroyed church of Santa Rufina (beside the Via Cornelia, the modern Via di Boccea) in 1968, Lady Wheeler found several ...

Tópico(s): Historical and Religious Studies of Rome

1969 - Cambridge University Press | Papers of the British School at Rome

Artigo Acesso aberto Revisado por pares

Dennis Stauss, Cornelia Brunner, Friederike Berberich‐Siebelt, Uta E. Höpken, Martin Lipp, Gerd Müller,

Abstract Follicular T helper (Tfh) cells are key regulators of the germinal center reaction and long‐term humoral immunity. Tfh cell differentiation requires the sustained expression of the transcriptional repressor Bcl6; however, its regulation in CD4 + T cells is incompletely understood. Here, we report that the transcriptional coactivator Bob1, encoded by the Pou2af1 gene, promotes Bcl6 expression and Tfh cell development. We found that Bob1 together with the octamer transcription factors Oct1/Oct2 ...

Tópico(s): Immunotherapy and Immune Responses

2016 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Cornelia O’Callaghan-Sunol, Michael Y. Sherman,

AbstractUpon cancer progression in mouse models of prostate cancer, the heat shock transcription factor Hsf1 becomes strongly upregulated, especially in metastases. We hypothesized that Hsf1 plays a role in cell migration, a process necessary for metastases. Using a cell culture model of migration in a scratch, we found that immortalized MEF cells derived from hsf1-/- animals were deficient in both basal and EGF-induced migration. MEF cell migration was dependent on JNK and ERK signaling, since ...

Tópico(s): Endoplasmic Reticulum Stress and Disease

2006 - Taylor & Francis | Cell Cycle

Artigo Revisado por pares

Simon T. Belt, Cornelia Bohne, G. M. Charette, S. E. Sugamori, J. C. Scaiano,

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarbocation formation via carbene protonation studied by the technique of stopped-flow laser-flash photolysisSimon T. Belt, Cornelia Bohne, G. Charette, S. E. Sugamori, and J. C. ScaianoCite this: J. Am. Chem. Soc. 1993, 115, 6, 2200–2205Publication Date ( ...

Tópico(s): Atomic and Molecular Physics

1993 - American Chemical Society | Journal of the American Chemical Society

Carta Acesso aberto Revisado por pares

Cornelia Mutz, Raphaela Schwentner, Maximilian Kauer, Anna M. Katschnig, Florian Kromp, Dave N.T. Aryee, Sophie Erhardt, Michel Goiny, Javier Alonso, Dietmar Fuchs, Heinrich Kovar,

Ewing sarcoma (ES) is an aggressive pediatric tumor driven by the fusion protein EWS-FLI1. We report that EWS-FLI1 suppresses TDO2-mediated tryptophan (TRP) breakdown in ES cells. Gene expression and metabolite analyses reveal an EWS-FLI1-dependent regulation of TRP metabolism. TRP consumption increased in the absence of EWS-FLI1, resulting in kynurenine and kynurenic acid accumulation, both aryl hydrocarbon receptor (AHR) ligands. Activated AHR binds to the promoter region of target genes. We demonstrate ...

Tópico(s): Epigenetics and DNA Methylation

2016 - Wiley | FEBS Letters

Artigo Acesso aberto Revisado por pares

Simona Eliza Giușcă, Piotr Wierzbicki, Cornelia Amălinei, Irina-Draga Căruntu, Elena Roxana Avădănei,

Introduction. The impact of tumor cells on tumor-infiltrating lymphocytes (TILs) in cancer development is not yet clarified. Our study analyzed the distribution and prognostic value of CD4+ and CD8+ T lymphocytes in hepatocellular carcinoma (HCC) and liver metastases (LM). Material and methods. Archival tissue specimens of 35 HCC and 39 LM patients were immunohistochemically processed. The number of intratumoral (IT) and peritumoral (PT) CD4+ and CD8+ T cells was quantitatively analyzed. Results. We ...

Tópico(s): Immunotherapy and Immune Responses

2015 - Via Medica | Folia Histochemica et Cytobiologica

Artigo Acesso aberto Revisado por pares

Philipp J. Kahle, Cornelia Hertel,

Two types of nerve growth factor (NGF) receptors have been described: high affinity (class I) and low affinity (class II). Biological responses to NGF are thought to be mediated by class I receptors, whereas the role of class II receptors is less clear. While some neuronal cells express both receptor types, only class II receptors have been detected on glial cells. Two glial cell lines, peripheral Schwannoma D6P2T and central 33B glioma cells, were employed to investigate the properties of class II ...

Tópico(s): HER2/EGFR in Cancer Research

1992 - Elsevier BV | Journal of Biological Chemistry

Artigo Revisado por pares

Karin Eusterhues, Cornélia Rumpel, Ingrid Kögel‐Knabner,

Formation of long residence time carbon pools in soils is crucial for understanding the global carbon cycle. Acting on the assumption that chemical oxidation mimics natural oxidative processes, we treated forest floor, topsoil and subsoil samples from two acid forest soil profiles (Dystric Cambisol, Haplic Podzol) with H2O2. The oxidation-resistant organic carbon fraction was dated using 14C and found to be 500–3900 years older than the bulk soil material. A positive correlation between the oxidation- ...

Tópico(s): Heavy metals in environment

2005 - Elsevier BV | Organic Geochemistry

Artigo Acesso aberto Revisado por pares

Cornelia Rosu, Andrew Gorman, Rafael Cueto, Kerry M. Dooley, Paul S. Russo,

Particles with an open, porous structure can be used to deliver payloads. It is often of interest to detect such particles in tissue or materials, which is facilitated by addition of dye. A straightforward approach leading to fluorescent, porous silica particles is described. The particles are etched with 3 mM aqueous sodium hydroxide, taking advantage of the etching rate difference between normal silica and an interior band of silica that contains covalently attached dye. No additional steps, such ...

Tópico(s): Advanced biosensing and bioanalysis techniques

2016 - Elsevier BV | Journal of Colloid and Interface Science

Artigo Acesso aberto Revisado por pares

Cornelia Kurischko, Hong Kyung Kim, Venkata K. Kuravi, Juliane Pratzka, Francis C. Luca,

The mRNA-binding protein Ssd1 is a substrate for the Saccharomyces cerevisiae LATS/NDR orthologue Cbk1, which controls polarized growth, cell separation, and cell integrity. We discovered that most Ssd1 localizes diffusely within the cytoplasm, but some transiently accumulates at sites of polarized growth. Cbk1 inhibition and cellular stress cause Ssd1 to redistribute to mRNA processing bodies (P-bodies) and stress granules, which are known to repress translation. Ssd1 recruitment to P-bodies is ...

Tópico(s): RNA and protein synthesis mechanisms

2011 - Rockefeller University Press | The Journal of Cell Biology