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Revisão Acesso aberto Revisado por pares

Alemayehu Amberbir, Sabrina H. Lin, Joshua A. Berman, Adamson S. Muula, Darren Jacoby, Emily Wroe, Cecilia Promise Maliwichi-Nyirenda, Victor Mwapasa, Amelia C. Crampin, Martha Makwero, Emmanuel Singogo, Sam Phiri, Stephen B. Gordon, Sheldon W. Tobe, Jones Masiye, Bradley J. Newsome, Mina C. Hosseinipour, Moffat Nyirenda, Joep J. van Oosterhout,

Global Heart is the official and primary publication of the World Heart Federation, offering a platform for the dissemination of knowledge on research, developments, trends, solutions and public health programmes in the area of cardiovascular disease. Global Heart welcomes research results, points of view and educational material on the prevention, treatment and control of cardiovascular disease with a special focus on low and middle-income countries which are facing the brunt of epidemiological ...

Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins

2019 - Elsevier BV | Global Heart

Artigo Acesso aberto Revisado por pares

Paluku Bahwere, Theresa Banda, Kate Sadler, Gertrude Nyirenda, Victor Owino, Bina Shaba, Filippo Dibari, Steve Collins,

Abstract The cost of ready‐to‐use therapeutic food ( RUTF ) used in community‐based management of acute malnutrition has been a major obstacle to the scale up of this important child survival strategy. The current standard recipe for RUTF [peanut‐based RUTF ( P ‐ RUTF ) ] is made from peanut paste, milk powder, oil, sugar, and minerals and vitamins. Milk powder forms about 30% of the ingredients and may represent over half the cost of the final product. The quality of whey protein concentrates 34% ( WPC 34) is ...

Tópico(s): Food Security and Health in Diverse Populations

2014 - Wiley | Maternal and Child Nutrition

Revisão Acesso aberto Revisado por pares

Joep J. van Oosterhout, Mina C. Hosseinipour, Adamson S. Muula, Alemayehu Amberbir, Emily Wroe, Josh Berman, Cecilia Promise Maliwichi-Nyirenda, Victor Mwapasa, Amelia C. Crampin, Martha Makwero, Emmanuel Singogo, Satish Gopal, Ulrika Baker, Samuel Phiri, Stephen B. Gordon, Sheldon W. Tobe, Jonathan Chiwanda, Jones Masiye, John Parks, Collins Mitambo, Austrida Gondwe, Luckson Dullie, Bradley J. Newsome, Moffat Nyirenda,

Global Heart is the official and primary publication of the World Heart Federation, offering a platform for the dissemination of knowledge on research, developments, trends, solutions and public health programmes in the area of cardiovascular disease. Global Heart welcomes research results, points of view and educational material on the prevention, treatment and control of cardiovascular disease with a special focus on low and middle-income countries which are facing the brunt of epidemiological ...

Tópico(s): Global Health and Surgery

2019 - Elsevier BV | Global Heart

Artigo Acesso aberto Revisado por pares

Rainier Masa, Gina Chowa, Victor Nyirenda,

The objective of this study was to examine the prevalence and predictors of food insecurity among people living with HIV (PLHIV) in two rural communities in Zambia. A cross-sectional sample of 101 PLHIV was surveyed using the Household Food Insecurity Access Scale. In multivariable linear regression models, income, household possessions, and perceived coping strategies were significantly associated with decreased food insecurity. Debt and perceived mental distress were significantly associated with ...

Tópico(s): Homelessness and Social Issues

2017 - Taylor & Francis | Ecology of Food and Nutrition

Artigo Acesso aberto Revisado por pares

Rainier Masa, Gina Chowa, Victor Nyirenda,

The intersection of nutrition and HIV underscores the importance of adequate food and a diverse diet. In communities with high prevalence of food insecurity and HIV, there is a substantial co-occurrence of low dietary diversity, undernutrition, and adverse health outcomes.The aim of this study was to identify correlates of individual dietary diversity (IDD) and its association with health outcomes for people living with HIV (PLHIV) in rural Zambia.The study used a cross-sectional design using data ...

Tópico(s): Food Security and Health in Diverse Populations

2018 - SAGE Publishing | Nutrition and Health

Artigo Acesso aberto Revisado por pares

Rainier Masa, Gina Chowa, Victor Nyirenda,

The objective of this study was to evaluate the impact of Chuma na Uchizi, a livelihood intervention for people living with HIV (PLHIV) in rural Eastern Province, Zambia, on food security. The intervention included cash transfers to purchase income-generating assets, access to a savings account, and life-skills training. The study employed a non-equivalent groups design to compare intervention (n = 50) and control participants (n = 51) who were receiving outpatient care from two comparable health facilities ...

Tópico(s): Homelessness and Social Issues

2018 - Johns Hopkins University Press | Journal of Health Care for the Poor and Underserved

Artigo Acesso aberto Revisado por pares

Rainier Masa, Gina Chowa, Victor Nyirenda,

In Zambia, more people living with HIV now have access to lifesaving antiretroviral therapy than ever before. However, progress in HIV treatment and care has not always resulted in lower mortality. Adherence remains a critical barrier to treatment success. The objective of this study was to examine the barriers and facilitators of antiretroviral therapy adherence, particularly the role of household economic status. The study included a cross-sectional sample of 101 people living with HIV (PLHIV) ...

Tópico(s): HIV, Drug Use, Sexual Risk

2017 - Taylor & Francis | African Journal of AIDS Research

Artigo Acesso aberto Revisado por pares

Bright Mukanga, Natasha Mwila, Herbert Tato Nyirenda, Victor Daka,

Abstract Background Globally, hormonal contraceptives have proved to be effective in the prevention of unwanted pregnancies. However, despite evidence of the many benefits associated with the use of hormonal contraceptives, concerns related to their safety and side effects have been reported. We conducted a study to explore the perspectives on the side effects of hormonal contraceptives among women of reproductive age in Kitwe district of Zambia. Methods An explorative qualitative study was done ...

Tópico(s): Adolescent Sexual and Reproductive Health

2023 - BioMed Central | BMC Women s Health

Carta Acesso aberto Revisado por pares

Misheck Chileshe, David Mulenga, Ruth Lindizyani Mfune, Tato Herbert Nyirenda, James Mwanza, Bright Mukanga, Steward Mudenda, Victor Daka,

The novel Coronavirus Disease-2019 which was first reported on 31st December, 2019 in Wuhan city, China has resulted in over 889, 256 deaths and over 27 million infections worldwide. In Zambia there have been a total of 295 deaths among which there were 214 brought-in-dead (BID). This high number of BIDs raises critical questions about the health seeking behaviour among the Zambian population. There is need to investigate drivers of community deaths. Here we postulate possible causes and suggest ...

Tópico(s): COVID-19 Clinical Research Studies

2020 - African Field Epidemiology Network | Pan African Medical Journal

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Amy Greer, San-San Ou, Ethan Wilson, Estelle Piwowar‐Manning, Michael Forman, Marybeth McCauley, Theresa Gamble, Cholticha Ruangyuttikarn, Mina C. Hosseinipour, Nagalingeswaran Kumarasamy, Mulinda Nyirenda, Beatriz Grinsztejn, José Henrique Pilotto, Natthapol Kosashunhanan, Marineide Gonçalves de Melo, Joseph Makhema, Victor Akelo, Ravindre Panchia, Sharlaa Badal‐Faesen, Ying Qing Chen, Myron S. Cohen, Susan H. Eshleman, Chloe L. Thio, Alexandra Valsamakis,

Data comparing hepatitis B virus (HBV) infection in HIV-infected [HIV(+)], and HIV-uninfected [HIV(-)] individuals recruited into the same study are limited. HBV infection status and chronic hepatitis B (cHB) were characterized in a multinational clinical trial: HIV Prevention Trials Network (HPTN 052).HBV infection status at enrollment was compared between HIV(+) (N = 1241) and HIV(-) (N = 1232) from 7 HBV-endemic countries. Hepatitis B e antigen and plasma HBV DNA were determined in cHB. Median CD4, median ...

Tópico(s): HIV/AIDS Research and Interventions

2017 - Lippincott Williams & Wilkins | JAIDS Journal of Acquired Immune Deficiency Syndromes

Artigo Acesso aberto Revisado por pares

Oscar Divala, Alemayehu Amberbir, Zahra Ismail, Teferi Beyene, Daniela Garone, Colin Pfaff, Victor Singano, Harriet Akello, Martias Joshua, Moffat Nyirenda, Alfred Matengeni, Josh Berman, Jane Mallewa, Gift S. Chinomba, Noel Kayange, Theresa J. Allain, Adrienne K. Chan, Sumeet Sodhi, Joep J. van Oosterhout,

Hypertension and diabetes prevalence is high in Africans. Data from HIV infected populations are limited, especially from Malawi. Integrating care for chronic non-communicable co-morbidities in well-established HIV services may provide benefit for patients by preventing multiple hospital visits but will increase the burden of care for busy HIV clinics.Cross-sectional study of adults (≥18 years) at an urban and a rural HIV clinic in Zomba district, Malawi, during 2014. Hypertension and diabetes were ...

Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins

2016 - BioMed Central | BMC Public Health

Artigo Acesso aberto

Bright Mukanga, Kupuzo Sakala, Tato Herbert Nyirenda, Victor Daka, David Mulenga,

Introduction: Dental caries and periodontal diseases are the most common oral diseases globally. Early control of oral health behaviours is important because lifestyles acquired during adolescence are powerful predictors of adult health. We conducted a study to determine knowledge, attitude and practices on oral hygiene among school going adolescents in Choma District. Methodology: A cross-sectional study was conducted among school going adolescents in randomly selected schools in Choma District. ...

Tópico(s): Global Maternal and Child Health

2022 - African Journals OnLine | Medical Journal of Zambia

Artigo Acesso aberto

Bright Mukanga, Herbert Tato Nyirenda, Nancy Choka, David Mulenga, Victor Daka,

Abstract: Verbal abuse during childbirth constitutes a violation of women's human rights and indicates poor maternal health care. The aim of the study was to investigate experiences and drivers of verbal abuse among women in Ndola and Kitwe health facilities. The study adopted a cross-sectional survey. Qualitative and quantitative data using questionnaires and focus group interviews were employed. The study was done in the Ndola and Kitwe districts of Zambia. The target population were women attending ...

Tópico(s): Grief, Bereavement, and Mental Health

2021 - Informa | Cogent Medicine

Artigo Acesso aberto Revisado por pares

Moffat Nyirenda, Roderick Carter, Justin I-Shing Tang, Annick de Vries, Christina Schlumbohm, Stephen G. Hillier, Frank Streit, Michael Oellerich, Victor W. Armstrong, Eberhard Fuchs, Jonathan R. Seckl,

OBJECTIVE Recent studies in humans and animal models of obesity have shown increased adipose tissue activity of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which amplifies local tissue glucocorticoid concentrations. The reasons for this 11β-HSD1 dysregulation are unknown. Here, we tested whether 11β-HSD1 expression, like the metabolic syndrome, is “programmed” by prenatal environmental events in a nonhuman primate model, the common marmoset monkey. RESEARCH DESIGN AND METHODS We used a “fetal ...

Tópico(s): Stress Responses and Cortisol

2009 - American Diabetes Association | Diabetes

Revisão Acesso aberto Brasil Produção Nacional Revisado por pares

Angela Loyse, Jessica Burry, Jennifer H. Cohn, Nathan Ford, Tom Chiller, Isabela Ribeiro, Sinata Koulla‐Shiro, Janneth Mghamba, Angela Ramadhani, Rose Nyirenda, Sani Aliyu, Douglas Wilson, Thuy Le, Rita Oladele, Sokoine Lesikari, Conrad Muzoora, Newton Kalata, Elvis Temfack, Yacouba Njankouo Mapoure, Victor Sini, Duncan Chanda, Meshack Shimwela, Shabir Lakhi, Jonathon Ngoma, Lilian Gondwe-Chunda, Chase Perfect, Amir Shroufi, Isabelle Andrieux‐Meyer, Adrienne K Chan, Charlotte Schutz, Mina C. Hosseinipour, Charles van der Horst, Jeffrey D. Klausner, David R. Boulware, Robert S. Heyderman, David G. Lalloo, Jeremy Day, Joseph N Jarvis, Márcio L. Rodrigues, Shabbar Jaffar, David W. Denning, Chantal Migone, Megan Doherty, Olivier Lortholary, Françoise Dromer, Muirgen Stack, Síle F. Molloy, Tihana Bicanic, Joep van Oosterhout, Peter Mwaba, Cecilia Kanyama, Charles Kouanfack, Sayoki Mfinanga, Nelesh P. Govender, Thomas S. Harrison,

In 2018, WHO issued guidelines for the diagnosis, prevention, and management of HIV-related cryptococcal disease. Two strategies are recommended to reduce the high mortality associated with HIV-related cryptococcal meningitis in low-income and middle-income countries (LMICs): optimised combination therapies for confirmed meningitis cases and cryptococcal antigen screening programmes for ambulatory people living with HIV who access care. WHO's preferred therapy for the treatment of HIV-related cryptococcal ...

Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment

2018 - Elsevier BV | The Lancet Infectious Diseases

Artigo

Jared M. Baeten, Thesla Palanee‐Phillips, Nyaradzo Mgodi, Ashley J. Mayo, Daniel Szydlo, Gita Ramjee, Brenda Gati Mirembe, Felix Mhlanga, Portia Hunidzarira, Leila E. Mansoor, Samantha Siva, Vaneshree Govender, Bonus Makanani, Logashvari Naidoo, Nishanta Singh, Gonasagrie Nair, Lameck Chinula, Urvi M. Parikh, John W. Mellors, Iván C. Balán, Kenneth Ngure, Ariane van der Straten, Rachel Scheckter, Morgan Garcia, Melissa Peda, Karen Patterson, Edward Livant, Katherine Bunge, Devika Singh, Cindy Jacobson, Yuqing Jiao, Craig W. Hendrix, Zvavahera M. Chirenje, Clemensia Nakabiito, Taha E. Taha, Judith Jones, Kristine Torjesen, Annaléne Nel, Zeda Rosenberg, Lydia Soto‐Torres, Sharon L. Hillier, Elizabeth R. Brown, Dorothy Aanyu, John Abima, Janne Abullarade, Priyanka Agarwal, Surabhi Ahluwalia, Simon Africa Akasiima, Carolyne A. Akello, Samuel Albert, Motsamai Alphale, Calins Alphonse, Lucy Apeduno, Sara Aranda, Orly Aridor, Shakeera Arnolds, Prossy Asiimwe, Millicent Atujuna, Didas Atwebembere, Lakshmi Baboolall, Kiran Badana, Jared M. Baeten, David Balamusani, Iván C. Balán, Gabriel Banda, Towera Whitney Banda, Jennifer Baugh, James Amos Baziira, May A. D. Antonio, Sivuyisiwe Asanda Bebeza, Linda‐Gail Bekker, Ian M. Bell, Meagan J. Bemer, Richard Berman, Jennifer Berthiaume, Linda Bezak, Yashveer Bhagwandin, Hassen Anwar Bhayat, Nokulunga Bhengu, Sonto Bhengu, Aruna Bhoola, Florence Asiimwe Biira, Daniel Bittoni, Roberta Black, Nombuso Jacqueline Blose, Pearl Boks, Stephen G. Bolton, Phathiswa Botya, Amanda Brown, Elizabeth R. Brown, Helen Brown, Robyn Helen Bruce, Luke Erismus Bukenya, Aidah Bukirwa, Katherine Bunge, Lisa Bunts, Fezile Buthelezi, Mbongeleni William Buthelezi, Samkelisiwe Dumisile Buthelezi, Rose Byogero, Samiksha Byroo, Robert Byuma, Johanna Albertha Carstens, Allison Carter, Nazneen Cassim, Busisiwe Cebekhulu, Bongekile Cele, Dolly Judith Cele, Phindile Cele, Simangele Cele, Sithabile Cele, Mary Chadza, Nahida Chakhtoura, Claire Chapdu, Gift Chareka, Charles Chasakara, Manju Chatani-Gada, Diana Chetty, Mary Chidanyika, Tafadzwa Tariro Lisa Chifambi, Emelder Chihota, Sungano Chikono, Anesu Chikonyora, Brett Dzidzai Chikukwa, Craig Chin, Mary Chindevu, Lameck Chinula, Tendai Blessing Chinyanda, Thandiwe Chirenda, Zvavahera M. Chirenje, Chiedza Chirisa, Patience Chisale, Angela Chishanga, Tobias Chitambo, Fred Chitema, Flora Chithila, Tinei Helen Chitowa, Catherine Chitsinde, Gladys Chitsulo, Miria Chitukuta, Spiwe Chiveso, Nelecy Chome, Phumelele Fortune Chonco, Emily Christopher, Kerusha Chunderduri, Vutomi Cibi, Naana Cleland, Thobeka Coba, Mandy Rae Cobbing, Clare Collins, Kim Comer, Shameen Cozzi, Danielle Crida, Sufia Dadabhai, Thembakazi Daki, Nwabisa Danster, Reshmi Dassaye, Renita David, Jontraye M. Davis, Sumaya Dawood, Pallabi Deb, Leslie Degnam, Tiffany Derrick, Bríd Devlin, Charlene S. Dezzutti, Patricia Mae Dhlakama, Lorna Dias, Jean Chivoniso Dimairo, Elaine Dinnie, Avile Dlabanta, Msizi Dladla, Thandeka Immaculate Dladla, Andile Princess Dlungele, Curtis Dolezal, Kristine Donaty, Clare Dott, Jenna Dubbs, Vuyiseka Dubula, Pamella Dukwe, Cebo Ivan Duma, Portia Ignatia Makhosazana Duma, Promise Duma, Vimbai Kudzanai Duncan, Luis Duran, Lindelwa Dyabeni, Andrew M. Edwards, Radhika Etikala, Juliane Etima, Lee Fairlie, Henry H. Fischer, Jacqueline Fitzpatrick, Llewellyn Fleurs, Mary Glenn Fowler, Lester Freeman, Zakir Gaffoor, Lizzy Gama, Morgan Garcia, Anita Bhatia Garg, Vanesa Margret Gatsi, Clifford Gcwensa, Emmanuel Lwandile Gebashe, Samantha Geduld, Jennipher Gelant, Donna Germuga, Joseph Ggita, Rebecca Giguere, Lucy Godo, Breanna J Goetz, Litha Gogo, Esther Goliati, Daniel K. Gondwe, Kelley C. Gordon, Rodney Goreraza, Jayandree Gounden, Dhevium Govender, Justin Sivalingum Govender, Nerusha Govender, Subramonien Govender, Vaneshree Govender, Nonkululeko Nosipho Gqwara, Anisa Gravelle, Phindile Guga, Victor Guma, Delisile Zilungile Gumede, Sibusiso Gumede, Thembelihle Gumede, Thobeka Winifred Gumede, Orgrah Gundani, Ravi Gunnam, Rahul Gupta, Mirriam Gwande, Xolani Gxako, Kim Hall, Wayne Hall, Perry Hargrave, Ishana Harkoo, Tanya M. Harrell, Amy Heaps, Simone Lara Hendricks, Craig W. Hendrix, Bongeka Hlabisa, Lungile Bongeka Hlabisa, Kudzai Hlahla, Thulebona Martin Hlela, Thandiwe Hobongwana, Eva K. Horn, Ridley Howard, Haixiao Huang, Portia Hunidzairia, Nivriti Hurbans, Marla Husnik, Tendai Doreen Hwehwe, Rabia Imamdin, Amina Ismail, Ebrahiema Jacobs, Cindy Jacobson, Ashleigh Catherine Jacques, Jane Jamabya, Grace James, Karla Janse van Rensburg, Ziningi Nobuhle Jaya, Nitesha Jeenarain, Lauren Jennings, Haoping Jiang, Ning Jiang, Yuqing Jiao, Nwabisa Laurianne Jijana, Godfrey Jokoniya, Judith Jones, Mildred Kabasonga, Daniel Kizza Kabenge, Samuel Kabwigu, Evans Kachale, Lonely Kachenjera, Fiona Kachingamire, Emma I Kachipapa, Mary Kadiwa, McLoddy Kadyamusuma, Bosco Kafufu, Mary Mukasa Kagwa, Clare Kajura-Manyindo, Brenda Catherine Kakayi, Victoria Kaliwo, Dishiki Kalonji, Nyasha Elizabeth Kamanga, Betty Kamira, Zerif Kampangire, Getrude Kamwana, Justine Kamya, La-Donna Kapa, Patrick Karugaba, Khumbo Kasambara, Priya Kassim, Sheetal Kassim, Milly Katana, Francis Katongole,

Background Two phase 3 clinical trials showed that use of a monthly vaginal ring containing 25 mg dapivirine was well tolerated and reduced HIV-1 incidence in women by approximately 30% compared with placebo. We aimed to evaluate use and safety of the dapivirine vaginal ring (DVR) in open-label settings with high background rates of HIV-1 infection, an important step for future implementation. Methods We did a phase 3B open-label extension trial of the DVR (MTN-025/HIV Open-label Prevention Extension [ ...

Elsevier BV

Artigo Acesso aberto Revisado por pares

Trijn Israëls, Barnabas Atwiine, Caitlyn Duffy, Junious Sichali, Glenn Mbah Afungchwi, Kathy Pritchard‐Jones, Deborah Nyirenda, Victor Mwapasa,

Implementation science is a relatively young field of study and is the science of delivering evidence-based interventions into routine health care. RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) is an evaluation-type implementation science framework. CANCaRe Africa is preparing a project to assess the implementation and effectiveness of a cash incentive intervention to support families with out-of-pocket costs to prevent treatment abandonment and increase childhood cancer ...

Tópico(s): Acute Lymphoblastic Leukemia research

2024 - Elsevier BV | Pediatric Hematology Oncology Journal

Artigo Acesso aberto Revisado por pares

Friday Saidi, Sanya Shah, Madeleine Squibb, Lameck Chinula, Charity Nakanga, Tisungane Mvalo, Mitch Matoga, Agatha Bula, Maganizo Chagomerana, Funny Kamanga, Wiza Kumwenda, Tawonga Mkochi, Gladwell Masiye, I. Moya, Michael E. Herce, S. E. Rutstein, Virginia Thonyiwa, Rose Nyirenda, Victor Mwapasa, Irving Hoffman, Mina C. Hosseinipour,

Incident HIV during the perinatal period significantly impedes elimination of Mother-to-Child HIV Transmission (eMTCT) efforts. Pre-Exposure Prophylaxis (PrEP) effectively reduces HIV acquisition, and new agents like injectable Cabotegravir (CAB-LA) offer potential advantages for pregnant and breastfeeding women. The Pregnancy, Infant, and Maternal health Outcomes (PrIMO) study will compare rates of composite adverse pregnancy outcomes, and infant adverse events, growth and neurodevelopment between ...

Tópico(s): Adolescent Sexual and Reproductive Health

2024 - BioMed Central | BMC Public Health

Artigo Acesso aberto Revisado por pares

Jobiba Chinkhumba, Samuel Mpinganjira, Andrew Kumitawa, Mercy Malopa, Dalitso Longwe, Vincent Samuel Phiri, Tonney S. Nyirenda, Victor Mwapasa,

Economic consequences of COVID-19 illness and healthcare use for households in low income countries are not well known. We estimated costs associated with COVID-19 care-seeking and treatment from a household perspective and assessed determinants of treatment costs. A cross-sectional household survey was conducted between December 2020 and November 2021 in urban and peri-urban areas of Blantyre district. Adults (age ≥18 years) with confirmed COVID-19 were asked to report the symptoms they experienced ...

Tópico(s): COVID-19 Pandemic Impacts

2023 - Public Library of Science | PLOS Global Public Health

Artigo Acesso aberto

Bright Mukanga, Kupuzo Sakala, Tato Herbert Nyirenda, Victor Daka, David Mulenga,

Introduction: Dental caries and periodontal diseases are the most common oral diseases globally. Early control of oral health behaviours is important because lifestyles acquired during adolescence are powerful predictors of adult health. We conducted a study to determine knowledge, attitude and practices on oral hygiene among school going adolescents in Choma District. Methodology: A cross-sectional study was conducted among school going adolescents in randomly selected schools in Choma District. ...

Tópico(s): Vaccine Coverage and Hesitancy

2022 - African Journals OnLine | Medical Journal of Zambia

Artigo Acesso aberto Revisado por pares

Towela Nyirenda-Jere, Victor S. Frost, Nail Akar,

This paper deals with the impact of traffic handling mechanisms on capacity for different network architectures. Three traffic handling models are considered: per-flow, class-based and best-effort (BE). These models can be used to meet service guarantees, the major differences being in their complexity of implementations and in the quantity of network resources that must be provided. In this study, the performance is fixed and the required capacity determined for various combinations of traffic handling ...

Tópico(s): Advanced Optical Network Technologies

2004 - Elsevier BV | Computer Communications

Artigo

Towela Nyirenda-Jere, Victor S. Frost, Nail Akar,

This paper describes the impact of traffic handling mechanisms on network capacity for support of Quality of Service (QoS) in the Internet. The emergence of applications with diverse throughput, loss and delay requirements requires a network that is capable of supporting different levels of service as opposed to the single best-effort service that was the foundation of the Internet. As a result the Integrated Services (Intserv) and Differentiated Services (Diffserv) models have been proposed. The Intserv ...

Tópico(s): Advanced Optical Network Technologies

2001 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

Artigo Acesso aberto Revisado por pares

Alinune N. Kabaghe, Victor Singano, Danielle Payne, Alice Maida, Rose Nyirenda, Kelsey Mirkovic, Andreas Jahn, Pragna Patel, Kristin Brown, Mansour Farahani, Felix Kayigamba, Lyson Tenthani, Francis M. Ogollah, Andrew F. Auld, Fatima Zulu, Wezi Msungama, Nellie Wadonda-Kabondo,

The World Health Organization recommends Pre-Exposure Prophylaxis (PrEP) for all populations at substantial risk of HIV infection. Understanding PrEP awareness and interest is crucial for designing PrEP programs; however, data are lacking in sub-Saharan Africa. In Malawi, oral PrEP was introduced in 2018. We analyzed data from the 2020 Malawi Population-based HIV Impact Assessment (MPHIA) to assess PrEP awareness and factors associated with PrEP interest in Malawi.MPHIA 2020 was a national cross-sectional ...

Tópico(s): Sex work and related issues

2023 - BioMed Central | BMC Infectious Diseases

Artigo Acesso aberto Revisado por pares

Prisca Benedicto-Matambo, Lindsay Avolio, Henry Badji, Rabab Batool, Farhana Khanam, Stephen Munga, Milagritos D. Tapia, Pablo Peñataro Yori, Alex O Awuor, Bubacarr Ceesay, Jennifer Cornick, Nigel A. Cunliffe, Paul F. Garcia Bardales, Christopher D. Heaney, Aneeta Hotwani, Mahzabeen Ireen, Md Taufiqul Islam, Ousman Jallow, Robert W. Kaminski, Wagner V Shapiama Lopez, Victor Maiden, Usman N. Ikumapayi, Ruth Nyirenda, John B. Ochieng, Richard Omore, Maribel Paredes Olórtegui, Patricia B. Pavlinac, Nora Pisanic, Firdausi Qadri, Sonia Qureshi, Nazia Rahman, Elizabeth T. Rogawski McQuade, Francesca Schiaffino, Ousman Secka, Catherine Sonye, Shazia Sultana, Drissa Timite, Awa Traoré, Mohammad Tahir Yousafzai, Md Taufiqur Rahman Bhuiyan, M Jahangir Hossain, Khuzwayo C. Jere, Margaret Kosek, Karen L. Kotloff, Farah Naz Qamar, Samba O. Sow, James A Platts-Mills,

Abstract Background Molecular diagnostics on human fecal samples have identified a larger burden of shigellosis than previously appreciated by culture. Evidence of fold changes in immunoglobulin G (IgG) to conserved and type-specific Shigella antigens could be used to validate the molecular assignment of type-specific Shigella as the etiology of acute diarrhea and support polymerase chain reaction (PCR)–based microbiologic end points for vaccine trials. Methods We will test dried blood spots collected ...

Tópico(s): Escherichia coli research studies

2024 - Oxford University Press | Open Forum Infectious Diseases

Artigo Acesso aberto Revisado por pares

Imukusi Mutanekelwa, Seter Siziya, Victor Daka, Kabelenga Elijah, Ruth Lindizyani Mfune, Misheck Chileshe, David Mulenga, Herbert Tato Nyirenda, Christopher Nyirenda, Steward Mudenda, Bright Mukanga, Kasonde Bowa,

Voluntary Medical Male Circumcision (VMMC) is a key intervention in HIV/AIDS. Improving VMMC program uptake in Zambia requires careful monitoring of adverse events (AE) to inform program quality and safety. We investigate the prevalence of VMMC AE and their associated factors among adult males in Ndola, Copperbelt Province, Zambia.We performed a cross-sectional study using secondary clinical data collected in 2015 using two validated World Health Organisation/Ministry of Health reporting forms. We ...

Tópico(s): Ethics and Legal Issues in Pediatric Healthcare

2021 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Revisado por pares

Melissa M. Medvedev, Victor Tumukunde, Ivan Mambule, Cally J Tann, Peter Waiswa, Ruth R Canter, Christian Holm Hansen, Elizabeth Ekirapa Kiracho, Kenneth Katumba, Catherine Pitt, Giulia Greco, Helen Brotherton, Diana Elbourne, Janet Seeley, Moffat Nyirenda, Elizabeth Allen, Joy E. Lawn,

Abstract Background There are 2.5 million neonatal deaths each year; the majority occur within 48 h of birth, before stabilisation. Evidence from 11 trials shows that kangaroo mother care (KMC) significantly reduces mortality in stabilised neonates; however, data on its effect among neonates before stabilisation are lacking. The OMWaNA trial aims to determine the effect of initiating KMC before stabilisation on mortality within seven days relative to standard care. Secondary objectives include exploring ...

Tópico(s): COVID-19 Impact on Reproduction

2020 - Springer Science+Business Media | Trials

Artigo Acesso aberto Revisado por pares

Vanessa Mdala, Deborah Nyirenda, Samuel Mpinganjira, Victor Mwapasa, Alinane Linda Nyondo‐Mipando,

Many studies in infectious diseases struggle to recruit participants. The SARS-CoV-2 infection, transmission dynamics, and household impact in Malawi (SCATHIM) study reported a refusal rate of 57.2%. Adequate publicity can lead to more people participating in studies. This study explored the reasons for participating in the SCATHIM study.

Tópico(s): Viral Infections and Outbreaks Research

2024 - BioMed Central | BMC Medical Research Methodology

Artigo Acesso aberto Revisado por pares

Scott Kaba Matafwali, Pipina A. Vlahakis, Victor Daka, Bwalya A. Witika, Herbert Tato Nyirenda, Namaunga Kasumu Chisompola, Chiluba Mwila,

Despite snakebite antivenom being included on the WHO list of essential medicines, many parts of the world, especially Africa, lack effective and safe antivenoms.A descriptive, field-based, cross-sectional study was undertaken from August to November 2020 in 40 out of 71 health facilities in Ndola district. Interviews and physical inspection were conducted at each facility.The study revealed that only three (8%) of all the private health facilities had antivenom available at the time of the assessment. ...

Tópico(s): Rabies epidemiology and control

2021 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene

Artigo Acesso aberto

Nsofwa Jubedah Mwansa, Victor Daka, David Mulenga, Ruth Lindizyani Mfune, Bright Mukanga, Christopher Nyirenda, Seter Siziya,

Background and Objective: Epilepsy is a neurological condition that has proven to be a major public health challenge worldwide, including Zambia. Despite the availability of many treatment alternatives, people with epilepsy still experience seizures. There is paucity of information on the control of seizures and associated factors in Zambia. The purpose of this study was to examine the factors associated with seizure control in people with epilepsy in two tertiary hospitals in Zambia. Methods: A ...

Tópico(s): Pharmacological Effects and Toxicity Studies

2020 - Global Health and Education Projects, Inc. | International Journal of Translational Medical Research and Public Health