A. Martinez, Jaume Vergés, Javier Antonio Herrera Muñoz,
... a un anticlinal de contorno oblicuo (anticlinal de Vilada-Lillet) situado en el manto infrayacente del Cadi. Este cabalgamiento inferior es intersectado, al oeste de Vilada, por el cabalgamiento de Vallfogona (cabalgamiento inferior del ...
Tópico(s): Archaeological and Historical Studies
1988 - University of Barcelona | Acta geológica hispánica/Acta geologica hispanica
J. Pertíñez Mena, L. Viladàs Jené, Thais Clusa Gironella, Ignacio Menacho Pascual, S. Nadal Gurpegui, Martí Solé,
Observar diferencias entre población étnica y autóctona en la frecuencia de trastornos mentales. Estudiar datos epidemiológicos y su nivel de registro. Estudio descriptivo. Área Básica de Salud Raval Sud. CAP Drassanes. Barcelona. Muestra aleatoria de 112 pacientes inmigrantes, pertenecientes a minorías étnicas, visitados entre enero de 1995 y diciembre de 1997, apareados por edad y sexo con 112 autóctonos. Se estudiaron variables relacionadas con patología mental en inmigrantes: edad, origen, motivo ...
Tópico(s): Immigration and Intercultural Education
2002 - Elsevier BV | Atención Primaria
Emilio Ramos, Pere Busquets, Jaume Vergés,
... termination of the Pedraforca thrust sheet and the Vilada anticline, and the frontal system of the Vallfogona ...
Tópico(s): Geological and Geophysical Studies Worldwide
2002 - Elsevier BV | Sedimentary Geology
Mayfong Mayxay, Rattanaphone Phetsouvanh, Catrin E. Moore, Vilada Chansamouth, Manivanh Vongsouvath, Syho Sisouphone, Pankham Vongphachanh, Thaksinaporn Thaojaikong, Soulignasack Thongpaseuth, Simmaly Phongmany, Valy Keolouangkhot, M Strobel, Paul N. Newton,
Summary Objective To examine the accuracy of the admission tourniquet test in the diagnosis of dengue infection among Lao adults. Methods Prospective assessment of the predictive diagnostic value of the tourniquet test for the diagnosis of dengue infection, as defined by IgM, IgG and NS1 ELISAs (Panbio Ltd, Australia), among Lao adult inpatients with clinically suspected dengue infection. Results Of 234 patients with clinically suspected dengue infection on admission, 73% were serologically confirmed ...
Tópico(s): Vector-borne infectious diseases
2010 - Wiley | Tropical Medicine & International Health
María José Parada, Helena Viladás,
Purpose This paper seeks to shed light on how core values are successfully transmitted in family businesses via narratives. Design/methodology/approach A qualitative‐interpretive approach is used. Data were collected through in‐depth interviews made to 17 family members from three family businesses of different ages, sizes, industries, and generations in control. The richness of these interviews, besides its depth and length, emerges from the complete picture formed by the comparison of the stories ...
Tópico(s): Corporate Finance and Governance
2010 - Emerald Publishing Limited | Journal of Organizational Change Management
Daniel H. Paris, Vilada Chansamouth, Pruksa Nawtaisong, Ester Löwenberg, Rattanaphone Phetsouvanh, Stuart D. Blacksell, S J Lee, Arjen M. Dondorp, T van der Poll, Paul N. Newton, Mark S. Levi, Nicholas Day,
Scrub typhus (caused by Orientia tsutsugamushi) and murine typhus (caused by Rickettsia typhi) cause up to 28% of febrile episodes in Thailand and Laos. The current understanding of coagulation and inflammation in the pathogenesis of these clinically very similar vasculotropic diseases is limited. This study compared human in vivo changes in 15 coagulation, inflammation and endothelial activation markers in prospectively collected admission and follow-up samples of 121 patients (55 scrub typhus, 55 ...
Tópico(s): Viral Infections and Vectors
2011 - Elsevier BV | Clinical Microbiology and Infection
Nicole Stoesser, Derrick W. Crook, Catrin E. Moore, Rattanaphone Phetsouvanh, Vilada Chansamouth, Paul N. Newton, Nicola Jones,
Sir, Antimicrobial resistance in common Gram-negative organisms such as Escherichia coli is a major threat to global health, and particularly relevant to clinical management in resource-poor settings, where access to appropriate antibiotics may be limited by cost. An example of this is the Lao Peoples' Democratic Republic (Laos), which has some of the poorest health indicators in the south-east Asia region,1 and borders several countries reporting high rates of CTX-M-mediated extended-spectrum β- ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2011 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Catrin E. Moore, Stuart D. Blacksell, Thaksinaporn Taojaikong, Richard G. Jarman, Robert V. Gibbons, Sue J. Lee, Vilada Chansamouth, Soulignasack Thongpaseuth, Mayfong Mayxay, Paul N. Newton,
Japanese encephalitis virus (JEV) is a major cause of encephalitis in Asia. We estimated the diagnostic accuracy of two anti-JEV immunoglobulin M (IgM) enzyme-linked immunosorbent assays (ELISAs) (Panbio and XCyton JEVCheX) compared with a reference standard (AFRIMS JEV MAC ELISA) in a prospective study of the causes of central nervous system infections in Laos. Cerebrospinal fluid (CSF; 515 patients) and serum samples (182 patients) from those admitted to Mahosot Hospital, Vientiane, were tested. The ...
Tópico(s): Viral Infections and Immunology Research
2012 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Mayfong Mayxay, Josée Castonguay-Vanier, Vilada Chansamouth, Audrey Dubot‐Pérès, Daniel H. Paris, Rattanaphone Phetsouvanh, Jarasporn Tangkhabuanbutra, Phouvieng Douangdala, Saythong Inthalath, Phoutthalavanh Souvannasing, Günther Slesak, Narongchai Tongyoo, Anisone Chanthongthip, Phonepasith Panyanouvong, Bountoy Sibounheuang, Koukeo Phommasone, Michael Dohnt, Darouny Phonekeo, Bouasy Hongvanthong, Sinakhone Xayadeth, Pakapak Ketmayoon, Stuart D. Blacksell, Catrin E. Moore, Scott B. Craig, Mary‐Anne Burns, Frank von Sonnenburg, Andrew L. Corwin, Xavier de Lamballerie, Iveth J. González, Eva Christophel, Amy Cawthorne, David Bell, Paul N. Newton,
Because of reductions in the incidence of Plasmodium falciparum malaria in Laos, identification of the causes of fever in people without malaria, and discussion of the best empirical treatment options, are urgently needed. We aimed to identify the causes of non-malarial acute fever in patients in rural Laos.For this prospective study, we recruited 1938 febrile patients, between May, 2008, and December, 2010, at Luang Namtha provincial hospital in northwest Laos (n=1390), and between September, 2008, ...
Tópico(s): Vector-borne infectious diseases
2013 - Elsevier BV | The Lancet Global Health
Rattanaphone Phetsouvanh, Thaksinaporn Thojaikong, Phonlavanh Phoumin, Bountoy Sibounheuang, Koukeo Phommasone, Vilada Chansamouth, Sue J. Lee, Paul N. Newton, Stuart D. Blacksell,
Inter- and intra-observer variation was examined among six microscopists who read 50 scrub typhus (ST) and murine typhus (MT) indirect immunofluorescence assay (IFA) immunoglobulin M (IgM) slides. Inter-observer agreement was moderate (κ = 0.45) for MT and fair (κ = 0.32) for ST, and was significantly correlated with experience ( P = 0.03 and P = 0.004, respectively); κ-scores for intra-observer agreement between morning and afternoon readings (range = 0.35–0.86) were not correlated between years of experience for ...
Tópico(s): Viral Infections and Vectors
2013 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Sabine Dittrich, Weerawat Phuklia, Gareth D. H. Turner, Sayaphet Rattanavong, Vilada Chansamouth, Stephen J. Dumler, David Ferguson, Daniel H. Paris, Paul N. Newton,
Neorickettsia sennetsu infection is rarely recognized, with less than 100 globally reported patients over the last 50 years. The disease is thought to be contracted by eating raw fish, a staple of many South-East Asian cuisines. In 2009, the first patient with sennetsu was identified in the Lao PDR (Laos), raising the question as to how common this organism and related species are in patients presenting with fever. We investigated the frequency of N. sennetsu infection at hospitals in diverse areas ...
Tópico(s): Parasite Biology and Host Interactions
2015 - Public Library of Science | PLoS neglected tropical diseases
Vilada Chansamouth, Syvilay Thammasack, Rattanaphone Phetsouvanh, Valy Keoluangkot, Catrin E. Moore, Stuart D. Blacksell, Josée Castonguay-Vanier, Audrey Dubot‐Pérès, Jarasporn Tangkhabuanbutra, Narongchai Tongyoo, Phooksavanh Souphaphonh, Onanong Sengvilaipaseuth, Manivanh Vongsouvath, Koukeo Phommasone, Davanh Sengdethka, Amphayvanh Seurbsanith, Scott B. Craig, Laura Hermann, M Strobel, Paul N. Newton,
Introduction Laos has the highest maternal mortality ratio in mainland Southeast Asia and a high incidence of infectious diseases. Globally, malaria has been the pathogen most intensively investigated in relation to impact on pregnancy, but there has been relatively little research on the aetiology and impact of other diseases. We therefore aimed to determine the causes and impact of fever in pregnant women admitted to two central hospitals in Vientiane City, Lao PDR (Laos). Materials and Methods ...
Tópico(s): Travel-related health issues
2016 - Public Library of Science | PLoS neglected tropical diseases
Paul N. Newton, Valy Keolouangkhot, Sue J. Lee, Khamla Choumlivong, Siho Sisouphone, Khamloune Choumlivong, Manivanh Vongsouvath, Mayfong Mayxay, Vilada Chansamouth, Viengmon Davong, Koukeo Phommasone, Joy Sirisouk, Stuart D. Blacksell, Pruksa Nawtaisong, Catrin E. Moore, Josée Castonguay-Vanier, Sabine Dittrich, Sayaphet Rattanavong, Ko Chang, Chirapha Darasavath, Oudayvone Rattanavong, Daniel H. Paris, Rattanaphone Phetsouvanh,
Abstract Background Murine typhus, or infection with Rickettsia typhi, is a global but neglected disease without randomized clinical trials to guide antibiotic therapy. Methods A prospective, open, randomized trial was conducted in nonpregnant, consenting inpatient adults with rapid diagnostic test evidence of uncomplicated murine typhus at 2 hospitals in Vientiane, Laos. Patients were randomized to 7 days (D7) or 3 days (D3) of oral doxycycline or 3 days of oral azithromycin (A3). Primary outcome ...
Tópico(s): Mosquito-borne diseases and control
2018 - Oxford University Press | Clinical Infectious Diseases
Audrey Dubot‐Pérès, Mayfong Mayxay, Rattanaphone Phetsouvanh, Sue J. Lee, Sayaphet Rattanavong, Manivanh Vongsouvath, Viengmon Davong, Vilada Chansamouth, Koukeo Phommasone, Catrin E. Moore, Sabine Dittrich, Olay Lattana, Joy Sirisouk, Phonelavanh Phoumin, Phonepasith Panyanivong, Amphonesavanh Sengduangphachanh, Bountoy Sibounheuang, Anisone Chanthongthip, Manivone Simmalavong, Davanh Sengdatka, Amphaivanh Seubsanith, Valy Keoluangkot, Prasith Phimmasone, Kongkham Sisout, Khamsai Detleuxay, Khonesavanh Luangxay, Inpanh Phouangsouvanh, Scott B. Craig, Suhella M. Tulsiani, Mary‐Anne Burns, David A. B. Dance, Stuart D. Blacksell, Xavier de Lamballerie, Paul N. Newton,
During 2003-2011, we recruited 1,065 patients of all ages admitted to Mahosot Hospital (Vientiane, Laos) with suspected central nervous system (CNS) infection. Etiologies were laboratory confirmed for 42.3% of patients, who mostly had infections with emerging pathogens: viruses in 16.2% (mainly Japanese encephalitis virus [8.8%]); bacteria in 16.4% (including Orientia tsutsugamushi [2.9%], Leptospira spp. [2.3%], and Rickettsia spp. [2.3%]); and Cryptococcus spp. fungi in 6.6%. We observed no significant ...
Tópico(s): Viral Infections and Vectors
2019 - Centers for Disease Control and Prevention | Emerging infectious diseases
Mayfong Mayxay, Phouvieng Douangdala, Chanthala Vilayhong, Koukeo Phommasone, Vilada Chansamouth, Manivanh Vongsouvath, Sayaphet Rattanavong, Ko Chang, Onanong Sengvilaipaseuth, Anisone Chanthongthip, Soulignasack Thongpaseuth, Paul N. Newton, Audrey Dubot‐Pérès,
Although Japanese encephalitis virus (JEV) infection is an important cause of acute febrile illness in Lao PDR (Laos), patient outcome has not been evaluated. We prospectively followed up 123 JEV-infected patients (70 children < 15 years and 53 adults ≥ 15 years) admitted at Mahosot Hospital, Vientiane, from 2003 to 2013. Japanese encephalitis virus infection was diagnosed by the detection of anti-JEV IgM in cerebrospinal fluid and/or IgM seroconversion. Neurological sequelae were assessed using the Liverpool ...
Tópico(s): Mosquito-borne diseases and control
2020 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Cherry Lim, Thyl Miliya, Vilada Chansamouth, Myint Thazin Aung, Abhilasha Karkey, Prapit Teparrukkul, Rahul Batra, Nguyen Phu Huong Lan, John Stelling, Paul Turner, Elizabeth A. Ashley, H. Rogier van Doorn, Htet Naing Lin, Clare Ling, Soawapak Hinjoy, Sopon Iamsirithaworn, Susanna Dunachie, Tri Wangrangsimakul, Viriya Hantrakun, William HK Schilling, Lam Minh Yen, Le Van Tan, Htay Htay Hlaing, Mayfong Mayxay, Manivanh Vongsouvath, Buddha Basnyat, Jonathan D. Edgeworth, Sharon J. Peacock, Guy Thwaites, Nicholas Day, Ben S. Cooper, Direk Limmathurotsakul,
Background Reporting cumulative antimicrobial susceptibility testing data on a regular basis is crucial to inform antimicrobial resistance (AMR) action plans at local, national, and global levels. However, analyzing data and generating a report are time consuming and often require trained personnel. Objective This study aimed to develop and test an application that can support a local hospital to analyze routinely collected electronic data independently and generate AMR surveillance reports rapidly. ...
Tópico(s): Urinary Tract Infections Management
2020 - JMIR Publications | Journal of Medical Internet Research
Tamalee Roberts, Sayaphet Rattanavong, Koukeo Phommasone, Vilada Chansamouth, Viengmon Davong, Valy Keoluangkhot, Sitthivone Hongsakhone, Naly Bounsavath, Mayfong Mayxay, Manivanh Vongsouvath, David A. B. Dance, Paul N. Newton,
Although typhoid is endemic to Southeast Asia, very little is known about the disease in Laos. Typhoid vaccination is not included in the national immunization program. Although sanitation has improved, one million people still do not have access to basic clean water sources. We describe the epidemiology and antimicrobial susceptibility patterns of Salmonella enterica serovar Typhi (S. Typhi) infection in Laos based on isolates accrued over 18 years at Mahosot Hospital, Vientiane. All blood cultures ...
Tópico(s): Nasal Surgery and Airway Studies
2020 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Philip N.D. Elders, Sandhya Dhawan, Ampai Tanganuchitcharnchai, Koukeo Phommasone, Vilada Chansamouth, Nicholas Day, Jose A. Garcia-Rivera, Jeffrey C. Hertz, Mayfong Mayxay, Manivanh Vongsouvath, Audrey Dubot‐Pérès, Matthew T. Robinson, Paul N. Newton, Stuart D. Blacksell,
Scrub typhus is a major cause of morbidity and mortality in Southeast Asia. Diagnosis of scrub typhus is difficult due to a lack of accessible validated diagnostic tools. Despite its objectivity, the diagnostic accuracy of ELISA tests is influenced by methodological and patient factors. This study aims to evaluate the performance of a novel in-house ELISA developed in the Mahidol Oxford Tropical Medicine Research Unit (MORU) for anti-scrub typhus group IgM and IgG compared to the “gold standard” reference ...
Tópico(s): Viral Infections and Vectors
2020 - Public Library of Science | PLoS neglected tropical diseases
Mohsen Naghavi, Dan J. Stein, Kevin S Ikuta, Lucien R Swetschinski, Authia P Gray, Eve E Wool, Gisela Robles Aguilar, Tomislav Meštrović, Georgia Smith, Chieh Han, Rebecca L. Hsu, Julian Chalek, Daniel T Araki, Erin Chung, Catalina Raggi, Anna Gershberg Hayoon, Nicole Davis Weaver, Paulina A Lindstedt, Amanda Smith, Umut Altay, Natalia V. Bhattacharjee, Konstantinos Giannakis, Frederick Fell, Barney McManigal, Nattwut Ekapirat, Jessica Andretta Mendes, Tilleye Runghien, Oraya Srimokla, Atef Abdelkader, Sherief Abd‐Elsalam, Richard Gyan Aboagye, Hassan Abolhassani, Hasan Abualruz, Usman Abubakar, Hana J Abukhadijah, Salahdein Aburuz, Ahmed Abu‐Zaid, Sureerak Achalapong, Isaac Yeboah Addo, Victor Adekanmbi, Temitayo Esther Adeyeoluwa, Qorinah Estiningtyas Sakilah Adnani, Leticia Akua Adzigbli, Muhammad Sohail Afzal, Saira Afzal, Antonella Agodi, Austin J Ahlstrom, Aqeel Ahmad, Sajjad Ahmad, Tauseef Ahmad, Ali Ahmadi, Ayman Ahmed, Haroon Ahmed, Ibrar Ahmed, Mohammed Ahmed, Saeed Ahmed, Syed Anees Ahmed, Mohammed Ahmed Akkaif, Salah Al Awaidy, Yazan Al Thaher, Samer O Alalalmeh, Mohammad T AlBataineh, Wafa Ali Aldhaleei, Adel Al‐Gheethi, Nma Bida Alhaji, Abid Ali, Liaqat Ali, Syed Shujait Ali, Waad Ali, Kasim Allel, Sabah Al-Marwani, Ahmad Alrawashdeh, Awais Altaf, Ala’a B. Al‐Tammemi, Jaffar A. Al‐Tawfiq, Karem H. Alzoubi, Walid Al-Zyoud, Ben Amos, John Amuasi, Robert Ancuceanu, Jason R. Andrews, Abhishek Anil, Iyadunni Adesola Anuoluwa, Saeid Anvari, Anayochukwu Edward Anyasodor, Geminn Louis Carace Apostol, Jalal Arabloo, Mosab Arafat, Aleksandr Y. Aravkin, Demelash Areda, Abdulfatai Aremu, Anton A Artamonov, Elizabeth A. Ashley, Marvellous O Asika, Seyyed Shamsadin Athari, Maha Atout, Tewachew Awoke, Sina Azadnajafabad, James M. Azam, Shahkaar Aziz, Ahmed Y. Azzam, Mahsa Babaei, François-Xavier Babin, Muhammad Badar, Atif Amin Baig, Milica Bajčetić, Stephen Baker, Mainak Bardhan, Hiba Jawdat Barqawi, Zarrin Basharat, Afisu Basiru, Mathieu Bastard, Saurav Basu, Nebiyou Simegnew Bayileyegn, Melaku Ashagrie Belete, Olorunjuwon Omolaja Bello, Apostolos Beloukas, James A. Berkley, Akshaya Srikanth Bhagavathula, Sonu Bhaskar, Soumitra S. Bhuyan, Julia Bielicki, Н. И. Брико, Colin Brown, Annie J. Browne, Danilo Buonsenso, Yasser Bustanji, Cristina Gardonyi Carvalheiro, Carlos A Castañeda-Orjuela, Muthia Cenderadewi, Joshua Chadwick, Sandip Chakraborty, Rama Mohan Chandika, Sara Chandy, Vilada Chansamouth, Vijay Kumar Chattu, Anis Ahmad Chaudhary, Patrick R Ching, Hitesh Chopra, Fazle Rabbi Chowdhury, Dinh‐Toi Chu, Muhammad Chutiyami, Natália Martins, Alanna Gomes da Silva, Omid Dadras, Xiaochen Dai, Samuel D Darcho, Saswati Das, Fernando de la Hoz, Denise Dekker, Kuldeep Dhama, Daniel Díaz, Benjamin F. R. Dickson, Serge Ghislain Djorie, Milad Dodangeh, Sushil Dohare, Клара Докова, Ojas Prakashbhai Doshi, Robert Kokou Dowou, Haneil Larson Dsouza, Susanna Dunachie, Arkadiusz Dziedzic, Tim Eckmanns, Abdelaziz Ed‐Dra, Aziz Eftekharimehrabad, Temitope Cyrus Ekundayo, Iman El Sayed, Muhammed Elhadi, Waseem El‐Huneidi, Christelle Elias, Sally Ellis, Randa Elsheikh, Ibrahim Elsohaby, Chadi Eltaha, Babak Eshrati, Majid Eslami, David W. Eyre, Adewale Oluwaseun Fadaka, Adeniyi Francis Fagbamigbe, Ayesha Fahim, Aliasghar Fakhri-Demeshghieh, Folorunso O. Fasina, Modupe M. Fasina, Ali Fatehizadeh, Nicholas Feasey, Alireza Feizkhah, Ginenus Fekadu, Florian Fischer, Ida Fitriana, Karen Forrest, Célia F. Rodrigues, John E Fuller, Muktar A Gadanya, Márió Gajdács, Aravind P. Gandhi, Esteban García-Gallo, Denise O Garrett, Rupesh K. Gautam, Miglas Welay Gebregergis, Mesfin Gebrehiwot, Teferi Gebru Gebremeskel, Christine Geffers, Leonidas Georgalis, Ramy Mohamed Ghazy, Mahaveer Golechha, Davide Golinelli, Melita A. Gordon, Snigdha Gulati, Rajat Das Gupta, Sapna Gupta, Vijai Kumar Gupta, Awoke Derbie Habteyohannes, Sebastian Haller, Harapan Harapan, Michelle Harrison, Ahmed I Hasaballah, Ikramul Hasan, Rumina Hasan, Hamidreza Hasani, Andrea Haselbeck, Md Saquib Hasnain, Ikrama Hassan, Shoaib Hassan, Mahgol Sadat Hassan Zadeh Tabatabaei, Khezar Hayat, Jiawei He, Omar E Hegazi, Mohammad Heidari, Kamal Hezam, Ramesh Holla, Marianne Holm, Heidi Hopkins, Md Mahbub Hossain, Mehdi Hosseinzadeh, Sorin Hostiuc, Nawfal R Hussein, Lê Đức Huy, Elsa D. Ibáñez-Prada, Adalia Ikiroma, Irena Ilić, Sheikh Mohammed Shariful Islam, Faisal Ismail, Nahlah Elkudssiah Ismail, Chidozie Declan Iwu, Chinwe Juliana Iwu, Abdollah Jafarzadeh, Fatoumatta Jaiteh, Reza Jalilzadeh Yengejeh, Roland Dominic G. Jamora, Javad Javidnia, Talha Jawaid, Adam Jenney, Hyon Jin Jeon, Mohammad Jokar, Nabi Jomehzadeh, Tamás Joó, Nitin Joseph, Zul Kamal, Kehinde Kazeem Kanmodi, Rami S. Kantar, James Kapisi, Ibraheem M. Karaye, Yousef Khader, Himanshu Khajuria, Nauman Khalid, Faham Khamesipour, Ajmal Khan, Mohammad Jobair Khan, Muhammad Tariq Iqbal Khan, Vishnu Khanal, Feriha Fatima Khidri, Jagdish Khubchandani, Suwimon Khusuwan, Min Seo Kim, Adnan Kısa, V. A. Korshunov, Fiorella Krapp, Ralf Krumkamp, Mohammed Kuddus, Mukhtar Kulimbet, Dewesh Kumar, Emmanuelle A. P. Kumaran, Ambily Kuttikkattu, Hmwe Hmwe Kyu, Iván Landires, Basira Kankia Lawal, Thao T. Le, I Lederer, Munjae Lee, Seung Won Lee, Alain Lepape, Temesgen Leka Lerango, Virendra S Ligade, Cherry Lim, Stephen S Lim, Liknaw Workie Limenh,
Antimicrobial resistance (AMR) poses an important global health challenge in the 21st century. A previous study has quantified the global and regional burden of AMR for 2019, followed with additional publications that provided more detailed estimates for several WHO regions by country. To date, there have been no studies that produce comprehensive estimates of AMR burden across locations that encompass historical trends and future forecasts.
Elsevier BV
Vilada Chansamouth, Mayfong Mayxay, David A. B. Dance, Tamalee Roberts, Rattanaxay Phetsouvanh, Bouakham Vannachone, Manivanh Vongsouvath, Viengmon Davong, Phout Inthavong, Syseng Khounsy, Bounxou Keohavong, Valy Keoluangkhot, Khamla Choumlivong, Nicholas Day, Paul Turner, Elizabeth A. Ashley, H. Rogier van Doorn, Paul N. Newton,
Objectives To review the scientific evidence base on antimicrobial use (AMU) and antimicrobial resistance (AMR) in human and animal sectors in the Lao PDR (Laos). Methods We reviewed all publications from July 1994 (the first article describing AMR in Laos) to December 2020. Electronic searches were conducted using Google Scholar and PubMed with specific terms relating to AMR and AMU in Lao, French and English languages. Findings We screened 1,357 peer-reviewed and grey reports by title and abstract ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2021 - BMJ | BMJ Global Health
Tamalee Roberts, Daniel M. Parker, Philip L. Bulterys, Sayaphet Rattanavong, Ivo Elliott, Koukeo Phommasone, Mayfong Mayxay, Vilada Chansamouth, Matthew T. Robinson, Stuart D. Blacksell, Paul N. Newton,
Background Scrub typhus (ST) and murine typhus (MT) are common but poorly understood causes of fever in Laos. We examined the spatial and temporal distribution of ST and MT, with the intent of informing interventions to prevent and control both diseases. Methodology and principle findings This study included samples submitted from 2003 to 2017 to Mahosot Hospital, Vientiane, for ST and MT investigation. Serum samples were tested using IgM rapid diagnostic tests. Patient demographic data along with ...
Tópico(s): Viral Infections and Vectors
2021 - Public Library of Science | PLoS neglected tropical diseases
Christopher J L Murray, Kevin S Ikuta, Fablina Sharara, Lucien R Swetschinski, Gisela Robles Aguilar, Authia P Gray, Chieh Han, Catherine Bisignano, Puja C Rao, Eve E Wool, Sarah Charlotte Johnson, Annie J. Browne, Michael G. Chipeta, Frederick Fell, Sean Hackett, Georgina Haines–Woodhouse, Bahar H. Kashef Hamadani, Emmanuelle A. P. Kumaran, Barney McManigal, Sureeruk Achalapong, Ramesh Agarwal, Samuel Akech, Samuel B Albertson, John Amuasi, Jason R. Andrews, Aleskandr Aravkin, Elizabeth A. Ashley, François-Xavier Babin, Freddie Bailey, Stephen Baker, Buddha Basnyat, Adrie Bekker, Rose G Bender, James A. Berkley, B. Adhisivam, Julia Bielicki, Suppawat Boonkasidecha, James Bukosia, Cristina Gardonyi Carvalheiro, Carlos A Castañeda-Orjuela, Vilada Chansamouth, Suman Chaurasia, Sara Chiurchiù, Fazle Rabbi Chowdhury, Rafai Clotaire Donatien, Aislinn Cook, Ben S. Cooper, Tim R. Cressey, Elia Criollo-Mora, Matthew Cunningham, Saffiatou Darboe, Nicholas Day, Maia De Luca, Клара Докова, Angela Dramowski, Susanna Dunachie, Thuy Duong Bich, Tim Eckmanns, Daniel Eibach, Amir Emami, Nicholas Feasey, Natasha Fisher-Pearson, Karen Forrest, Coralith Garcia, Denise O Garrett, Petra Gastmeier, Ababi Zergaw Giref, Rachel Greer, Vikas Gupta, Sebastian Haller, Andrea Haselbeck, Simon I Hay, Marianne Holm, Susan Hopkins, Yingfen Hsia, Kenneth Iregbu, Jan Jacobs, Daniel Jarovsky, Fatemeh Javanmardi, Adam Jenney, Meera Khorana, Suwimon Khusuwan, Niranjan Kissoon, Elsa Kobeissi, Tomislav Kostyanev, Fiorella Krapp, Ralf Krumkamp, Ajay Kumar, Hmwe Hmwe Kyu, Cherry Lim, Kruy Lim, Direk Limmathurotsakul, Michael J. Loftus, Miles Lunn, Jianing Ma, Anand Manoharan, Florian Marks, Jürgen May, Mayfong Mayxay, Neema Mturi, Tatiana Múnera‐Huertas, Patrick Musicha, Lilian A Musila, Marisa Márcia Mussi‐Pinhata, Ravi Naidu, Tomoka Nakamura, Ruchi Nanavati, Sushma Nangia, Paul N. Newton, Chanpheaktra Ngoun, Amanda Novotney, Davis Nwakanma, Christina W. Obiero, Theresa J. Ochoa, Antonio Olivas‐Martínez, Piero Olliaro, Edna Ooko, Edgar Ortíz‐Brizuela, Pradthana Ounchanum, Gideok D Pak, José Luis Paredes, Anton Y. Peleg, Carlo Perrone, Thong Phe, Koukeo Phommasone, Nishad Plakkal, Alfredo Ponce‐de‐León, Mathieu Raad, Tanusha Ramdin, Sayaphet Rattanavong, Amy Riddell, Tamalee Roberts, Julie V. Robotham, Anna Roca, Víctor Rosenthal, Kristina E. Rudd, Neal Russell, Hélio S. Sader, Weerawut Saengchan, Jesse Schnall, John A. Scott, Samroeng Seekaew, Mike Sharland, Madhusudhan Shivamallappa, José Sifuentes‐Osornio, Andrew J. H. Simpson, Nicolas Steenkeste, Andrew J. Stewardson, Temenuga Stoeva, Nidanuch Tasak, Areerat Thaiprakong, Guy Thwaites, Caroline Tigoi, Claudia Turner, Paul Turner, H. Rogier van Doorn, Sithembiso Velaphi, Avina Vongpradith, Manivanh Vongsouvath, Huong T L Vu, Timothy R. Walsh, Judd L. Walson, Seymour Waner, Tri Wangrangsimakul, Prapass Wannapinij, Teresa M. Wozniak, Tracey E M W Young Sharma, Kalvin Yu, Peng Zheng, Benn Sartorius, Alan D Lopez, Andy Stergachis, Catrin E. Moore, Christiane Dolecek, Mohsen Naghavi,
Summary Background Antimicrobial resistance (AMR) poses a major threat to human health around the world. Previous publications have estimated the effect of AMR on incidence, deaths, hospital length of stay, and health-care costs for specific pathogen–drug combinations in select locations. To our knowledge, this study presents the most comprehensive estimates of AMR burden to date. Methods We estimated deaths and disability-adjusted life-years (DALYs) attributable to and associated with bacterial AMR for ...
Tópico(s): Global Maternal and Child Health
2022 - Elsevier BV | The Lancet
Annie J. Browne, Michael G. Chipeta, Frederick Fell, Georgina Haines–Woodhouse, Bahar H. Kashef Hamadani, Emmanuelle A. P. Kumaran, Gisela Robles Aguilar, Barney McManigal, Jason R. Andrews, Elizabeth A. Ashley, Allan Audi, Stephen Baker, Happy Banda, Buddha Basnyat, Godfrey Bigogo, Chanpheaktra Ngoun, Vilada Chansamouth, Angeziwa Chunga, John D. Clemens, Viengmon Davong, Gordon Dougan, Susanna Dunachie, Nicholas Feasey, Denise O Garrett, Melita A. Gordon, Rumina Hasan, Andrea Haselbeck, Nathaniel J Henry, Robert S. Heyderman, Marianne Holm, Hyon Jin Jeon, Abhilasha Karkey, Farhana Khanam, Stephen P. Luby, Faisal Malik, Florian Marks, Mayfong Mayxay, James Meiring, Catrin E. Moore, Patrick K. Munywoki, Patrick Musicha, Paul N. Newton, Gideok Pak, Koukeo Phommasone, Sunil Pokharel, Andrew J. Pollard, Firdausi Qadri, Farah Naz Qamar, Sayaphet Rattanavong, Bobby Reiner, Tamalee Roberts, Samir K. Saha, Senjuti Saha, Sadia Shakoor, Mila Shakya, Andrew J. H. Simpson, Jeffrey D Stanaway, Claudia Turner, Paul Turner, Jennifer R. Verani, Manivanh Vongsouvath, Nicholas Day, Mohsen Naghavi, Simon I Hay, Benn Sartorius, Christiane Dolecek,
Enteric fever, a systemic infection caused by Salmonella enterica serovars Typhi and Paratyphi A, remains a major cause of morbidity and mortality in low-income and middle-income countries. Enteric fever is preventable through the provision of clean water and adequate sanitation and can be successfully treated with antibiotics. However, high levels of antimicrobial resistance (AMR) compromise the effectiveness of treatment. We provide estimates of the prevalence of AMR S Typhi and S Paratyphi A in ...
Tópico(s): Antibiotic Resistance in Bacteria
2024 - Elsevier BV | The Lancet Global Health
Margot Anderson, Khonesavanh Luangxay, Kongkham Sisouk, Latdavan Vorlasan, Bandith Soumphonphakdy, Vanmaly Sengmouang, Vilada Chansamouth, Koukeo Phommasone, Russell Van Dyke, Euming Chong, David A. B. Dance, Rattanaphone Phetsouvanh, Paul N. Newton,
Abstract As data about the causes of neonatal sepsis in low-income countries are inadequate, we reviewed the etiology and antibiotic susceptibilities of bacteremia in young infants in Laos. As Staphylococcus aureus is the leading cause of bacteremia in Lao infants, we also examined risk factors for this infection, in particular the local practice of warming mothers during the first weeks postpartum with hot coals under their beds (hot beds). Clinical and laboratory data regarding infants aged 0–60 ...
Tópico(s): Pneumonia and Respiratory Infections
2013 - Oxford University Press | Journal of Tropical Pediatrics
Judith Recht, Vilada Chansamouth, Nicholas J. White, Elizabeth A. Ashley,
Abstract Nitrofurantoin, a broad-spectrum antibiotic available since 1953, is used widely for the treatment of urinary tract infections as it often retains activity against drug-resistant uropathogens. It is contraindicated in pregnant women at term, and in neonates. Like trimethoprim/sulfamethoxazole, nitrofurantoin carries a warning for patients with known sensitivity to oxidant drugs, notably glucose-6-phosphate dehydrogenase (G6PD) deficiency, in whom it may cause haemolytic anaemia. This is ...
Tópico(s): Methemoglobinemia and Tumor Lysis Syndrome
2022 - Oxford University Press | JAC-Antimicrobial Resistance
Damien Ming, Vanheuang Phommadeechack, Phonepasith Panyanivong, Davanh Sengdatka, Weerawat Phuklia, Vilada Chansamouth, Tamalee Roberts, Stuart D. Blacksell, Paul N. Newton, Matthew T. Robinson,
In the Lao People's Democratic Republic (Laos), rickettsial infections, including scrub and murine typhus, account for a significant burden of fevers. The Mahosot Hospital Microbiology Laboratory in Vientiane, Laos, routinely performs rickettsial isolation from hospitalized patients with suspected rickettsioses using mammalian cell culture systems. We review the clinical and laboratory factors associated with successful Orientia tsutsugamushi and Rickettsia typhi isolations from this laboratory over ...
Tópico(s): Mosquito-borne diseases and control
2020 - American Society for Microbiology | Journal of Clinical Microbiology
Vilada Chansamouth, Danoy Chommanam, Tamalee Roberts, Sommay Keomany, Viladeth Paphasiri, Chanthala Phamisith, Siho Sengsavang, Khamsay Detleuxay, Phisith Phoutsavath, Sengvong Bouthavong, Anousone Douangnouvong, Manivanh Vongsouvath, Sommana Rattana, Bounxou Keohavong, Nicholas Day, Paul Turner, H. Rogier van Doorn, Mayfong Mayxay, Elizabeth A. Ashley, Paul N. Newton,
Antimicrobial use (AMU) is a key driver of antimicrobial resistance (AMR). There are few data on AMU, to inform optimizing antibiotic stewardship, in the Lao PDR (Laos).Point prevalence surveys (PPS) of AMU were conducted at four-month intervals in six general hospitals across Laos from 2017 to 2020, using modified Global-PPS data collection tools. The surveys focused on AMU amongst hospitalized inpatients.The overall prevalence of inpatient AMU was 71% (4,377/6,188), varying by hospital and survey round ...
Tópico(s): Pneumonia and Respiratory Infections
2022 - Elsevier BV | The Lancet Regional Health - Western Pacific
Karina-Doris Vihta, N Claire Gordon, Nicole Stoesser, T. Phuong Quan, Carina S.B. Tyrrell, Manivanh Vongsouvath, Elizabeth A. Ashley, Vilada Chansamouth, Paul Turner, Clare Ling, David W. Eyre, Nicholas J. White, Derrick W. Crook, Tim Peto, A. Sarah Walker,
Abstract Antimicrobial resistance (AMR) surveillance in bloodstream infections (BSIs) is challenging in low/middle-income countries (LMICs) given limited laboratory capacity. Other specimens are easier to collect and process and are more likely to be culture-positive. In 8102 E. coli BSIs, 322,087 E. coli urinary tract infections, 6952 S. aureus BSIs and 112,074 S. aureus non-sterile site cultures from Oxfordshire (1998–2018), and other (55,296 isolates) rarer commensal opportunistic pathogens, antibiotic ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2021 - Nature Portfolio | Scientific Reports
Vilada Chansamouth, Rose McGready, Danoy Chommanam, Soukanya Homsombath, Mayfong Mayxay, Paul N. Newton,
Laos has the highest maternal mortality ratio in mainland Southeast Asia but there has been little research conducted with pregnant women. We aim to discuss ethical challenges in enrolling pregnant women in research as a part of large pregnancy cohort study in Laos. From 2013 to 2015, a prospective cohort study was conducted with 1000 pregnant women in a rural area of Vientiane, Laos, to determine whether fevers were associated with maternal morbidity and small for gestational age. Incidence of ...
Tópico(s): Child Nutrition and Water Access
2017 - BioMed Central | Reproductive Health
Businesses are finally beginning to get the idea that design may be a tool to help them thrive in the marketplace. But the messages they get about what design is and how profitable it can be are mixed. How can we as designers best explain, in terms that make sense to management, how and why to use design?
Tópico(s): Management and Organizational Studies
2009 - Wiley | Design Management Review