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Andrew Robson, Lilian Thuram, Alyn Shipton, Michael Joseph, Pat McAuley, Robert Cole, Lucas Radebe, Andrew Pierce, DJM, James Moore, Zahid Hussain, Adam Sherwin Media Reporter, Don Howe, Thierry Henry, Jose-Luis Chilavert, Michael Owen, Richard Hobson, Jane Bolton, John Belstead, Philip Howard, Shay given, Carol Midgley, A. Shell, David Chater, David Trezeguet, James Bone, Rachel Campbell-Johnston, Nic Hopkins, Tom Finney, Tim Williams, Richard S. D. Ogilvy, Carl Mortished, Patrick Kidd, Vitor Baia, Sam Lister, Clare Stewart, Joe Joseph, Giles Coren, Simon Peter Firth, Ben Webster Transport Correspondent, David McVay, Howard Davies, Thrasy Petropoulos, Gabriel Batistuta, Jennai Cox Fitness Editor, Angus MacLeod Scottish Political Correspondent, Gary Lineker, Terry Butcher, Dominic Walsh, Tom Bawden, Rachel Holmes, Pauleta, Vincenzo Montella, Rory Watson, Nigel Hawthorne, Billy Wright, Jimmy Greaves, Gianluigi Buffon, Ruth Gledhill Religion Correspondent, Richard Ford Home Correspondent, Alan Hamilton, Stephen Farrell, Kevin Sampson, David Seaman, Simon Barnes Chief Sports, Jimmy Armfield, David Hands, Raul, Mark Bushell, Mark Pougatch, Matt Dickinson Chief Football Correspondent, Ian McIntyre, Greg Hurst, Anthea Lawson, Nicholas Wapshott, Caroline Merrell Banking Correspondent, Stanley Matthews, Christian Vieri, Simon Tait, Roger Scruton, Paula Hawkins, Peter Wright, Robert Cole City Correspondent, David Rowan, Vanora Bennett, Bobby Charlton, Thomas Linke, Sarah Johnson, Oliver Kahn, Ray Wilson, Tom Baldwin, Mark Henderson Science Correspondent, Martin Peters, Michael Gardiner, Karen Homer, Simon de Bruxelles, John Barnes, Geoffrey Dean, Roberto Carlos, Rio Ferdinand, J. M. Bryce, Edward Young, Neil Harman Tennis Correspondent, Martin Samuel, Raymond Keene, Rui Costa, John Russell Taylor, Matt Dickinson, Jerzy Dudek, Fernando Hierro, Johnny Haynes, Jonathan Dimbleby, Bronwen Maddox, Melissa Kite, Russell Hotten, Richard Owen, Tola Awogbamiye, Thomas Sorensen, Isadora Shilling, Noel Gallagher, Nick Hasell, Robbie Fowler, Lucio, Steve Claridge, Bryan Robson, David Hands Rugby Correspondent, Bobby Moore, Elizabeth Price, Francesco Totti, John Allison, T. C. B. Dehn, Nicholas Bethell, Tom Bentley, Anne Ashworth, Nick Szczepanik, Joanna Pitman, Mary Ann Sieghart, James Doran, Giles Whittell, Philip Webster Political Editor, Christopher Walker, Anne E. Kornblut, Juan Sebastian Veron, Roberto Ayala, Kevin McCarra, Alessandro Nesta, Chris McGrath, George Caulkin, Tim Wapshott, John Crosland and Michael Horsnell, Stewart Tendler and Andrew Pierce, Ingrid Mansell, Michael Austin, Peter Riddell, Lea Paterson Economics Editor, Geoff Hurst, Alex Benady, Nasser Hussain, Ben Webster, David Charter Chief Political Correspondent, Philip Webster, Richard Owen and Michael Evans Defence Editor, Michael Dynes, Simon Jenkins, Gary Duncan Economics Correspondent, Catherine Philp, Martin Waller, Michael Horsnell, Chris Ayres, Wilf Mannion, Alan Coren, Laura Peek, Benedict Nightingale, Angus Batey, Richard Nunn, Richard Beeston and Michael Evans, Stephen Dalton, Richard Morrison, Tim Lawson-Cruttenden, Bill Edgar, Alice Miles, Fabien Barthez, Adam Sherwin, Ray Davies, Roger Byrne, Sally Patten, Ashley Cole, Conal Gregory, Juan Valeron, Tom Rasmussen, Hernan Crespo, Boyd Goldie, Patience Wheatcroft, Jack Charlton, David Lister Ireland Correspondent,

... Batistuta Argentina Christian Vieri Italy Robbie Fowler England Vincenzo Montella Italy Raul Spain And a Dark Horse Djibril ...

2002 - Gale Group | TDA

Artigo Revisado por pares

Alfonso Montella, Vincenzo Punzo, Salvatore Chiaradonna, Filomena Mauriello, Marcello Montanino,

Point-to-point (P2P) speed enforcement is a relatively new approach to traffic law enforcement. Its technology allows vehicles whose average speed exceeds the speed limit over the controlled section to be fined. It therefore encourages compliance over distances longer than those where spot enforcement policies have been in place. In this paper, a procedure for consistently setting speed limits with such enforcement systems is proposed. Such a method has been applied to design the speed limits on ...

Tópico(s): Traffic Prediction and Management Techniques

2015 - Elsevier BV | Transportation Research Part C Emerging Technologies

Artigo Acesso aberto Revisado por pares

Francesco Patti, Manuela De Stefano, Luigi Lavorgna, Silvia Messina, Clara Grazia Chisari, Domenico Ippolito, Roberta Lanzillo, Veria Vacchiano, Sabrina Realmuto, Paola Valentino, G. Coniglio, Maria Buccafusca, Damiano Paolicelli, Alessandro d’Ambrosio, Patrizia Montella, Vincenzo Brescia Morra, Giovanni Savettieri, Bruno Alfano, Antonio Gallo, Isabella Laura Simone, Rosa Gemma Viterbo, Mario Zappia, Simona Bonavita, Gioacchino Tedeschi,

Background Magnetic Resonance Imaging (MRI) techniques provided evidences into the understanding of cognitive impairment (CIm) in Multiple Sclerosis (MS). Objectives To investigate the role of white matter (WM) and gray matter (GM) in predicting long-term CIm in a cohort of MS patients. Methods 303 out of 597 patients participating in a previous multicenter clinical-MRI study were enrolled (49.4% were lost at follow-up). The following MRI parameters, expressed as fraction (f) of intracranial volume, were ...

Tópico(s): Multiple Sclerosis Research Studies

2015 - Public Library of Science | PLoS ONE

Revisão Acesso aberto Revisado por pares

Marcella La Noce, Francesca Paino, Anna Spina, Pasqualina Naddeo, Roberta Montella, Vincenzo Desiderio, Alfredo De Rosa, Gianpaolo Papaccio, Virginia Tirino, Luigi Laino,

Stem cells have the ability to rescue and/or repair injured tissue. In humans, it is possible to isolate different types of stem cells from the body. Among these, dental pulp stem cells (DPSCs) are relatively easily obtainable and exhibit high plasticity and multipotential capabilities. In particular they represent a gold standard for neural-crest-derived bone reconstruction in humans and can be used for the repair of body defects in low-risk autologous therapeutic strategies.An electronic search ...

Tópico(s): Electrospun Nanofibers in Biomedical Applications

2014 - Elsevier BV | Journal of Dentistry

Artigo Revisado por pares

Raffaele Addeo, Alessandro Sgambato, Gregorio Cennamo, Liliana Montella, Vincenzo Faiola, Alberto Abbruzzese, Elena Capasso, Luigi Leo, Gerardo Botti, Michele Caraglia, Salvatore Del Prete,

Background The concept of metronomic chronic administration of low-dose chemotherapy has become relevant for the treatment of cancer in the last several years. This study sought to determine the safety and activity of oral vinorelbine (VNB), using a metronomic schedule of administration, in elderly patients with metastatic breast cancer (MBC). Patients and Methods From October 2004 to March 2007, 34 patients with MBC (median age, 74 years; range, 70–84 years) were treated with oral VNB at 70 mg/m2, ...

Tópico(s): HER2/EGFR in Cancer Research

2010 - Elsevier BV | Clinical Breast Cancer

Artigo Revisado por pares

Antonella Zucchetto, Renato Talamini, Luigino Dal Maso, Eva Negri, Jerry Polesel, Valerio Ramazzotti, Maurizio Montella, Vincenzo Canzonieri, Diego Serraino, Carlo La Vecchia, Silvia Franceschi,

Abstract A role of hormone‐related factors in renal cell cancer (RCC) etiology has been hypothesized, but the epidemiological evidence is inconsistent. The present study aimed at evaluating the effect of reproductive, menstrual and other gender‐specific variables on RCC risk among women. This study is part of a larger hospital‐based, case‐control study on RCC risk, conducted in northern, central and southern Italy. Cases were 273 women, below age 80, with histologically confirmed, incident RCC. Controls ...

Tópico(s): Renal cell carcinoma treatment

2008 - Wiley | International Journal of Cancer

Artigo Revisado por pares

Emanuela Balestrieri, Sandro Grelli, Claudia Matteucci, Antonella Minutolo, Gabriella d’Ettorre, Fiorella Di Sora, Francesco Montella, Vincenzo Vullo, Stefano Vella, Cartesio Favalli, Beatrice Macchi, Antonio Mastino,

Abstract The simultaneous expression of 19 apoptosis‐related genes was analyzed by RNA‐protection assay in peripheral blood mononuclear cells of HIV‐infected patients before and during successful antiretroviral therapy (ART). After 12 months of therapy, the expression of the pro‐apoptotic genes FAS , FAS‐L , FAF‐1 , FADD , CASPASE‐8 , DR3 , TRAIL , TNFR‐1 , TRADD , and BAX was significantly downregulated with respect to time 0, while that of BCL‐2 , BCL‐XL , and MCL‐1 was significantly upregulated. The data suggest that ...

Tópico(s): Cell death mechanisms and regulation

2006 - Wiley | Journal of Medical Virology

Capítulo de livro Revisado por pares

Antonino Mazzeo, Nicola Mazzocca, Roberto Nardone, Luca D’Acierno, Bruno Montella, Vincenzo Punzo, Egidio Quaglietta, Immacolata Lamberti, P. Marmo,

Prediction of service availability in railway systems requires an increasing attention by designers and operators in order to satisfy acceptable service quality levels offered to passengers. For this reason it is necessary to reach high availability standards, relying on high-dependable system components or identifying effective operational strategies addressed to mitigate failure effects. To this purpose, in this paper an innovative architecture is proposed to simulate railway operation in order ...

Tópico(s): Railway Systems and Energy Efficiency

2011 - Springer Science+Business Media | Lecture notes in computer science

Artigo Acesso aberto Revisado por pares

Nunzio Del Gaudio, Antonella Di Costanzo, Ning Qing Liu, Lidio Conte, Carmela Dell’Aversana, Guglielmo Bove, Rosaria Benedetti, Liliana Montella, Fortunato Ciardiello, Vincenzo Carafa, Concetta Ambrosino, Valeria Tucci, Mariarosaria Conte, Joost H.A. Martens, Hendrik G. Stunnenberg, Angela Nebbioso, Lucia Altucci,

Abstract Background The dynamic epigenome and proteins specialized in the interpretation of epigenetic marks critically contribute to leukemic pathogenesis but also offer alternative therapeutic avenues. Targeting newly discovered chromatin readers involved in leukemogenesis may thus provide new anticancer strategies. Accumulating evidence suggests that the PRC1 complex member CBX2 is overexpressed in solid tumors and promotes cancer cell survival. However, its role in leukemia is still unclear. ...

Tópico(s): Cancer-related gene regulation

2022 - BioMed Central | Molecular Cancer

Artigo Acesso aberto Revisado por pares

Marco Maglione, Silvia Montella, Carmine Mollica, Vincenzo Carnovale, Paola Iacotucci, Fabiola De Gregorio, Antonella Tosco, Mariarosaria Cervasio, Valeria Raia, Francesca Santamaria,

Primary ciliary dyskinesia (PCD) and cystic fibrosis (CF) are increasingly compared. There are no chest magnetic resonance imaging (MRI) comparative studies of PCD and CF. We assessed clinical, functional, microbiological and MRI findings in PCD and mild CF patients in order to evaluate different expression of lung disease. Twenty PCD (15.1 years) and 20 CF subjects with mild respiratory impairment (16 years, 70% with pancreatic insufficiency) underwent MRI, spirometry, and sputum cultures when clinically ...

Tópico(s): Cerebrospinal fluid and hydrocephalus

2017 - BioMed Central | ˜The œItalian Journal of Pediatrics/Italian journal of pediatrics

Artigo Revisado por pares

Francesca Santamaria, Silvia Montella, Massimo Pifferi, Vincenzo Ragazzo, Sara De Stefano, Nicoletta De Paulis, Marco Maglione, Attilio Boner,

Non-cystic fibrosis (CF) bronchiectasis is now identified more often than in the past.It was the aim of this study to assess the high-resolution computed tomography (HRCT) localization and extent of bronchiectasis and to determine whether asthma status, atopy and bronchiectasis distribution are associated with the etiology of bronchiectasis.We retrospectively analyzed clinical, laboratory, functional and HRCT data of 105 children with non-CF bronchiectasis at 2 tertiary respiratory units in Italy. ...

Tópico(s): Neonatal Respiratory Health Research

2008 - Karger Publishers | Respiration

Artigo Acesso aberto Revisado por pares

Luigino Dal Maso, Antonella Zucchetto, Carlo La Vecchia, Marco Montella, E. Conti, Vincenzo Canzonieri, Renato Talamini, Alessandra Tavani, Eva Negri, A. Garbeglio, Silvia Franceschi,

We investigated the influence of anthropometric measures at diagnosis and at different ages on prostate cancer risk using an Italian multicentre case–control study conducted between 1991 and 2002 of 1294 histologically confirmed cases and 1451 controls admitted to the same network of hospitals for acute non-neoplastic conditions. Height, weight, body mass index (BMI), waist-to-hip ratio, lean body mass 1 year before diagnosis/interview were not significantly associated with risk. However, a positive ...

Tópico(s): Prostate Cancer Treatment and Research

2004 - Springer Nature | British Journal of Cancer

Artigo Revisado por pares

Luigino Dal Maso, Silvia Franceschi, Eva Negri, E. Conti, Marco Montella, Salvatore Vaccarella, Vincenzo Canzonieri, Fabio Parazzini, Carlo La Vecchia,

The relationship between body mass measures at diagnosis and/or at different ages and ovarian cancer risk was investigated using an Italian multicentre case–control study. The study, conducted between 1992 and 1999, included 1031 cases of incident, histologically-confirmed epithelial ovarian cancer and 2411 controls admitted to the same network of hospitals for acute non-neoplastic conditions. Odds ratios (OR) and 95% confidence intervals (CI) were obtained using unconditional multiple logistic regression ...

Tópico(s): Endometrial and Cervical Cancer Treatments

2002 - Elsevier BV | European Journal of Cancer

Artigo Acesso aberto Revisado por pares

Melania Costantini, R Montella, Maria Paola Fadda, Vincenzo Tondolo, Gianluca Franceschini, Sonia Bove, Giorgia Garganese, Pierluigi Rinaldi,

Invasive lobular carcinoma is the second most common histologic form of breast cancer, representing 5% to 15% of all invasive breast cancers. Due to an insidious proliferative pattern, invasive lobular carcinoma remains clinically and radiologically elusive in many cases. Breast magnetic resonance imaging (MR) is considered the most accurate imaging modality in detecting and staging invasive lobular carcinoma and it is strongly recommended in pre-operative planning for all ILC. Contrast-enhanced ...

Tópico(s): Advanced MRI Techniques and Applications

2022 - Multidisciplinary Digital Publishing Institute | Journal of Personalized Medicine

Artigo Acesso aberto Revisado por pares

Luigino Dal Maso, Antonella Zucchetto, Alessandra Tavani, Maurizio Montella, Valerio Ramazzotti, Renato Talamini, Vincenzo Canzonieri, A. Garbeglio, Eva Negri, Annamaria Tonini, Carlo La Vecchia, Silvia Franceschi,

An increased risk of renal cell cancer (RCC) has been reported in overweight persons. The authors aimed to clarify which anthropometric measures are associated with risk of RCC and whether risk may vary according to selected variables. Between 1992 and 2004, they carried out an Italian multicenter case-control study including 767 (494 men, 273 women) incident cases of RCC and 1,534 hospital controls, frequency-matched to cases. To estimate odds ratios and 95% confidence intervals, they used conditional ...

Tópico(s): Cancer Risks and Factors

2007 - Oxford University Press | American Journal of Epidemiology

Artigo Acesso aberto Revisado por pares

Antonella Zucchetto, Luigino Dal Maso, Alessandra Tavani, Marco Montella, Valerio Ramazzotti, Renato Talamini, Vincenzo Canzonieri, A. Garbeglio, Eva Negri, Silvia Franceschi, Carlo La Vecchia,

An increased risk of renal cell cancer (RCC) has been reported in subjects with hypertension. Whether this association may vary according to sex, smoking, obesity, or RCC clinical presentation is unclear. Results on the link between diabetes mellitus and RCC are inconclusive.We conducted an Italian multicenter case-control study, including 767 (494 men, 273 women) incident cases of RCC, under 80 years of age, and 1534 hospital controls, frequency-matched to cases. Multiple logistic regression models, ...

Tópico(s): Cancer, Lipids, and Metabolism

2006 - Elsevier BV | Annals of Oncology

Artigo Acesso aberto Revisado por pares

Daniele Armenia, Domenico Di Carlo, Philippe Flandre, Yagaï Bouba, Vanni Borghi, Federica Forbici, Ada Bertoli, Caterina Gori, Lavinia Fabeni, William Gennari, Carmela Pinnetti, Annalisa Mondi, Stefania Cicalini, Roberta Gagliardini, Alessandra Vergori, Rita Bellagamba, Vincenzo Malagnino, Francesco Montella, Manuela Colafigli, Alessandra Latini, R. Marocco, M Licthner, Massimo Andreoni, Cristina Mussini, Francesca Ceccherini‐Silberstein, Andrea Antinori, Carlo Federico Perno, Maria Mercedes Santoro,

To evaluate the prevalence and therapeutic relevance of drug resistance among isolates from ART-experienced HIV-1-infected patients over the past two decades in Italy.Dynamics of resistance to one, two and three or more antiretroviral classes were evaluated from 1999-2018. Virological success (VS) after the latest therapy switch was evaluated according to cumulative class resistance and cumulative genotypic susceptibility score (Stanford HIV_DB algorithm).Among 13 663 isolates (from 6739 patients), ...

Tópico(s): HIV/AIDS Research and Interventions

2019 - Oxford University Press | Journal of Antimicrobial Chemotherapy

Artigo Acesso aberto Revisado por pares

Raffaella Cascella, Laura Stocchi, Claudia Strafella, Ivano Mezzaroma, M Mannazzu, Vincenzo Vullo, Francesco Montella, Giustino Parruti, Paola Borgiani, Federica Sangiuolo, Giuseppe Novelli, Antonella Pirazzoli, Stefania Zampatti, Emiliano Giardina,

Aim: Our work aimed to designate the optimal DNA source for pharmacogenetic assays, such as the screening for HLA-B*57:01 allele. Materials & methods: A saliva and four buccal swab samples were taken from 104 patients. All the samples were stored at different time and temperature conditions and then genotyped for the HLA-B*57:01 allele by SSP-PCR and classical/capillary electrophoresis. Results: The genotyping analysis reported different performance rates depending on the storage conditions of the ...

Tópico(s): T-cell and B-cell Immunology

2015 - Future Medicine | Pharmacogenomics

Artigo Revisado por pares

Francesça Chiaffarino, Fabio Parazzini, Cristina Bosetti, Silvia Franceschi, Renato Talamini, Vincenzo Canzonieri, Maurizio Montella, Valerio Ramazzotti, Silvia Franceschi, Carlo La Vecchia,

To analyse the risk factors for different histologic types of ovarian cancer, we conducted a case-control study. The cases included 750 women with incident, histologically confirmed invasive epithelial ovarian cancer subdivided into: 493 serous, 81 mucinous, 78 endometrioid, and 98 other histologies. The controls included 2411 women admitted to the same hospitals as cases. The odds ratios for women with three or more births, in comparison with nulliparae, were 0.6 for serous, 0.4 for endometrioid, ...

Tópico(s): Endometriosis Research and Treatment

2007 - Elsevier BV | European Journal of Cancer

Artigo Acesso aberto Revisado por pares

Liliana Montella, Raffaele Addeo, Vincenzo Faiola, Gregorio Cennamo, Rosario Guarrasi, Elena Capasso, Rosanna Mamone, Michele Caraglia, Salvatore Del Prete,

Chondrosarcomas and chordomas are usually chemoresistant bone tumors and may have a poor prognosis when advanced. They are usually associated with worsening pain difficult to control. Zoledronic acid was used in a 63-year-old man with metastatic chondrosarcoma and in a 66-year-old woman with a diagnosis of sacrum chordoma both reporting severe pain related to tumor. In the first case, zoledronic acid was able to maintain pain control despite disease progression following chemotherapy, in the other ...

Tópico(s): Sarcoma Diagnosis and Treatment

2009 - BioMed Central | Journal of Experimental & Clinical Cancer Research

Artigo Revisado por pares

Sandro Grelli, Emanuela Balestrieri, Claudia Matteucci, Antonella Minutolo, Gabriella d’Ettorre, Filippo Lauria, Francesco Montella, Vincenzo Vullo, Stefano Vella, Cartesio Favalli, Antonio Mastino, Beatrice Macchi,

Abstract: The impact of antiretroviral therapy (ART) on immune‐reconstitution and its relationship with the complex scenario of multiple cell signaling associated with apoptosis in HIV infection has not yet been fully elucidated. Here we report the results of the analysis of the expression of 13 genes involved in the apoptotic pathway, simultaneously detected by RNA‐protection assay in peripheral blood mononuclear cells (PBMCs) of 12 HIV‐1‐infected responder patients before and during successful ART. ...

Tópico(s): Phagocytosis and Immune Regulation

2006 - Wiley | Annals of the New York Academy of Sciences

Artigo Revisado por pares

Michele Caraglia, Raffaele Addeo, Raffaele Costanzo, Liliana Montella, Vincenzo Faiola, Elena Capasso, Salvatore Del Prete,

1576 Background: It has been recently demonstrated that pegylated liposomal doxorubicin (Caelyx, PLD) can cross the brain-blood barrier with a consequent accumulation in primitive and secondary brain tumours. Moreover, temozolamide (TMZ) is a new imidazo-tetrazine that accumulates in brain tissue and is used alone or in combination with radiotherapy in the treatment of primary and secondary brain tumours. The two drugs have been already used in combination in a phase I cinical study in the treatment ...

Tópico(s): Cancer Treatment and Pharmacology

2004 - Lippincott Williams & Wilkins | Journal of Clinical Oncology

Artigo Acesso aberto Revisado por pares

Michele Caraglia, Liliana Montella, Raffaele Addeo, Raffaele Costanzo, Vincenzo Faiola, Salvatore Del Prete, Feliciano Baldi, Alfonso Baldi, Alberto Abbruzzese, Marco Alloisio,

Tópico(s): Neuroblastoma Research and Treatments

2005 - Lippincott Williams & Wilkins | Journal of Clinical Oncology

Artigo Revisado por pares

Antonio Ricca, Francesca Montella, Gaetano Iaquaniello, Emma Palo, Annarita Salladini, Vincenzo Palma,

Selective propane dehydrogenation is one of the commercialised technology for the production of propylene. The main drawback of such process is closely linked to the high temperature required to reach a sustainable propane conversion that affects catalyst stability owing to coke formation on the catalyst surface. Accordingly, a periodic regeneration of catalytic bed is required. The simultaneous actions of performing the reaction in the presence of Pd-based membrane and optimization of employed ...

Tópico(s): Zeolite Catalysis and Synthesis

2017 - Elsevier BV | Catalysis Today

Artigo Acesso aberto Revisado por pares

Salvatore Del Prete, Liliana Montella, Michele Caraglia, Luigi Maiorino, Gregorio Cennamo, Vincenzo Montesarchio, G. Piai, Antonio Febbraro, Luciano Tarantino, Elena Capasso, Giovannella Palmieri, Rosario Guarrasi, M. Bianco, Rosanna Mamone, Clementina Savastano, Agata Pisano, Bruno Vincenzi, Antonietta Sabia, Alberto D’Agostino, Vincenzo Faiola, Raffaele Addeo,

Advanced hepatocellular carcinoma (HCC) not eligible for local therapies has limited chances of cure. Sorafenib is a multikinase inhibitor with proven activity in advanced HCC. Octreotide is used in this setting with conflicting results. Treatment with sorafenib and long-acting octreotide was tested in advanced HCC to evaluate safety and activity. Fifty patients with advanced HCC, Child-Pugh A or B, received sorafenib at a dosage of 800 mg/day for 28 days with a following week of rest and long-acting ...

Tópico(s): Liver physiology and pathology

2009 - Springer Science+Business Media | Cancer Chemotherapy and Pharmacology

Artigo Revisado por pares

Maurizio Montella, Anna Crispo, Ferdinando Frigeri, Domenico Ronga, Vincenzo Tridente, Mariarosaria De Marco, Gabriella Fabbrocini, Orlando Antonio Spada, Vincenzo Mettivier, Mario Tamburini,

Hepatitis C virus (HCV) is a RNA virus that cannot be integrated with the host genome; it can, however, exert its oncogenetic potential indirectly by contributing to the modulator effects of the host immune system, probably through a capacity to elude the immune system. We have carried out a case controlled study on tumors correlated with the immune system (multiple myeloma, non-Hodgkin lymphoma and Hodgkin disease) and HCV, in a high prevalence area. The relationship between each cancer and HCV infection ...

Tópico(s): Chronic Lymphocytic Leukemia Research

2001 - Elsevier BV | Leukemia Research