Goro Mouri, V. N. Golosov, Sergey Chalov, Belyaev Vladimir, Michiharu Shiiba, Tomoharu Hori, Seirou Shinoda, Taikan Oki,
Abstract In the Kotaki River Valley, Japan, the Fossa Magna has produced a large-scale collapse and landslide zone. Debris flows occur annually in the Kotaki River, which has headstreams in the Hakuba range (altitude: 2267 m) located in Niigata Prefecture. Sediment-related disasters occur over extensive areas from headwater to downstream cities and in a variety of forms. This will produce large quantities of upstream sand in the future, which may cause flooding through the deposition of sediment ...
Tópico(s): Soil erosion and sediment transport
2012 - Elsevier BV | CATENA
Аlexander K. Belyaev, Vladimir A. Polyanskiy, А. С. Семенов, D. A. Tretyakov, Yuriy A. Yakovlev,
Investigation of the correlation between measure of damage tensor and acoustic anisotropy of specimens from commercial alloy was carried out. The relationship between the principal values of damage tensor and the velocities of ultrasonic waves was established. The formula for acoustic anisotropy based on the principal values of damage tensor was proposed. It allows to describe the anisotropy of the accumulation of damages, which have a significant influence on acoustic anisotropy. The nonlinear ...
Tópico(s): Ultrasonics and Acoustic Wave Propagation
2017 - Elsevier BV | Procedia Structural Integrity
Salim R. Maduar, Aleksey V. Belyaev, Vladimir Lobaskin, Olga I. Vinogradova,
We show that an electro-osmotic flow near the slippery hydrophobic surface depends strongly on the mobility of surface charges, which are balanced by counterions of the electrostatic diffuse layer. For a hydrophobic surface with immobile charges, the fluid transport is considerably amplified by the existence of a hydrodynamic slippage. In contrast, near the hydrophobic surface with mobile adsorbed charges, it is also controlled by an additional electric force, which increases the shear stress at ...
Tópico(s): Nanopore and Nanochannel Transport Studies
2015 - American Physical Society | Physical Review Letters
Vladіslav Sadykov, Nikita Eremeev, E. M. Sadovskaya, A. Bobin, Yu.E. Fedorova, V. S. Muzykantov, Natalia Mezentseva, G. M. Alikina, T. A. Kriger, V. D. Belyaev, Vladimir A. Rogov, А. С. Улихин, Yu. S. Okhlupin, Н. Ф. Уваров, Oleg Bobrenok, Nikkia McDonald, James Watton, Aman Dhir, Robert Steinberger‐Wilckens, J. Mertens, Izaak C. Vinke,
Tópico(s): Electronic and Structural Properties of Oxides
2014 - Pleiades Publishing | Russian Journal of Electrochemistry
A. K. Dadivanyan, O. V. Noah, Yu. M. Pashinina, V. V. Belyaev, Vladimir G. Chigrinov, Д. Н. Чаусов,
Abstract The liquid crystals anchoring theory is considered on the molecular level. Earlier calculations of mesogenic molecules interaction energy with graphite and PE surface give results being one-two orders higher than experimentally obtained values. To explain the experimental values of anchoring energy we proposed its dependence on the interaction between liquid crystal layers. In our calculations we have simulated the mesogen molecules by virtual rod-like molecules. The molecules orientation ...
Tópico(s): Spectroscopy and Quantum Chemical Studies
2012 - Taylor & Francis | Molecular Crystals and Liquid Crystals
Аlexander K. Belyaev, Vladimir A. Polyanskiy, Yu. A. Yakovlev,
Tópico(s): Hydrogen embrittlement and corrosion behaviors in metals
2012 - Springer Science+Business Media | Acta Mechanica
A. K. Dadivanyan, Д. Н. Чаусов, O. V. Noa, V. V. Belyaev, Vladimir G. Chigrinov, Yu. M. Pashinina,
Tópico(s): Synthesis and Properties of Aromatic Compounds
2012 - Pleiades Publishing | Journal of Experimental and Theoretical Physics
V. A. Sobyanin, V. D. Belyaev, Vladimir Galvita,
Electrocatalytic conversion of methane over Ag-, Pt-, Ni- and Pt+CeO2-based electrode-catalysts in a cell with a solid oxygen conducting electrolyte: CH4,electrode-catalyst|0.9ZrO2+0.1Y2O3|Pt+PrO2,airwas studied at 660–850°C and the ratio of methane and electrochemically pumped oxygen flows of 0.8–2.0. Unlike Ag and Pt+CeO2 electrodes, the Ni and Pt electrodes were found to be active electrode-catalysts for partial oxidation of methane to syngas with the concentration ratio of [H2]/[CO]≈2.
Tópico(s): Catalysis and Oxidation Reactions
1998 - Elsevier BV | Catalysis Today
Аlexander K. Belyaev, Vladimir Palmov,
This article is aimed at the analysis of various theories enabling determination of fields of high-frequency vibration of complex dynamic structures. The considered theories are characterized by different degrees of information and ease of application. Chapter I deals with the classical theory of random vibration of complex structures. It gives full information on the vibration field of the structures, but it can hardly be practically applied in the case of the broad band random load. Further suggested ...
Tópico(s): Geophysics and Sensor Technology
1986 - Elsevier BV | Studies in applied mechanics
V. V. Belyaev, Vladimir G. Chigrinov,
A new figure of merit appropriate for optically addressed liquid-crystal spatial light modulators is derived. This figure of merit takes into account the change of phase retardation and switching time of a deformed liquid-crystal layer. The figure of merit is used in determining the optimal mix of polar and weak-polar components in the liquid-crystal layer.
Tópico(s): Advanced Optical Imaging Technologies
1993 - Optica Publishing Group | Applied Optics
V. D. Belyaev, Vladimir Galvita, V. A. Sobyanin,
Tópico(s): Advancements in Solid Oxide Fuel Cells
1998 - Akadémiai Kiadó | Reaction Kinetics and Catalysis Letters
Т. А. Парамонова, Ekaterina Machaeva, Belyaev Vladimir,
The estimation of modern parameters of 137 Cs root uptake was conducted in natural meadow and agricultural ecosystems of post-Chernobyl landscapes of Tula region.The agrosystems with main crops of field rotation (barley, potatoes, rape, maize) occupying watersheds and slopes with arable chernozems are contaminated at a level 460-670 Bq/kg (4.7-6.0Ci/km 2 ); natural meadow ecosystems occupying lower parts of slopes and floodplains are contaminated at a level 620-710 Bq/kg (5.8-7.6 Ci/km 2 ).In the arable ...
Tópico(s): Radioactivity and Radon Measurements
2015 - Federation of Eurasian Soil Science Societies | EURASIAN JOURNAL OF SOIL SCIENCE (EJSS)
Andrey Panchenko, Margarita L. Tyndyk, Mikhail Maydin, Ирина Балдуева, Anna Artemyeva, S. S. Kruglov, Galina S. Kireeva, A. G. Golubev, А. М. Belyaev, Vladimir N. Anisimov,
<b><i>Introduction:</i></b> The effects of chemotherapy are known to depend on the time of administration. Circadian rhythms are disturbed in tumors and in tumor bearers. Agents involved in controlling the circadian rhythms (chronobiotics) potentially can modify the outcomes of chemotherapeutics administered at different times of the day. Pineal hormone melatonin (MT) is a prototypic chronobiotic. <b><i>Objective:</i></b> The aim of the study was to investigate ...
Tópico(s): Light effects on plants
2020 - Karger Publishers | Chemotherapy
G Thomas, E. D. Williams, Dennis Becker, Bogdanova Ti, Eugene P. Demidchik, E F Lushnikov, Shigenobu Nagataki, В В Остапенко, Aldo Pinchera, G. Souchkevitch, М.D. Тronko, А. Ф. Цыб, Mark S. Tuttle, Shinpei Yamashita,
... S. Glotov, Anna L. Borisova, Oleg P. Balanovsky, Vladimir E. Belyaev, Oleg K. Granstrem, Luydmila Yu. Grivtsova, Anastasiya Yu. Efimenko, Maria S. Pokrovskaya, Tatyana A. Semenenko, Vladimir S. Sukhorukov, Andrey D. Kaprin, and Oxana M. ...
Tópico(s): Advances in Oncology and Radiotherapy
2000 - Mary Ann Liebert, Inc. | Thyroid
N. D. Belyaev, Vladimir G. Budker, Veronika Dubrovskaya, Andrej A. Kim, Елена Киселева, Victor N. Sidorov,
The outer surface of isolated metaphase chromosomes has been investigated by a method of thermally activated tritium labelling. We show that both chromosomal proteins and DNA are tritium-labelled. Fractionation of the chromosomal proteins reveals that scaffold proteins are the most labelled in condensed and EDTA-decondensed chromosomes. Exposition of some scaffold proteins on the outer surface of metaphase chromosomes is suggested.
Tópico(s): Muon and positron interactions and applications
1992 - Wiley | FEBS Letters
Nickolay D. Belyaev, Vladimir G. Budker, Ludmila V. Deriy, Irina A. Smolenskaya, Владимир Субботин,
During experimental CCl4 cirrhosis, an increase of membrane-associated factor stimulating 3T3 cell proliferation in vitro was observed. This stimulator is a 150-kD protein similar to one previously described. In situ perfusion released growth stimulatory activity, suggesting a peripheral plasma membrane protein localizing on basolateral surfaces. The activity increased with increasing number of CCl4 treatments, reaching a maximum at the 14th intoxication. It was faster than the proliferation of ...
Tópico(s): Liver Disease Diagnosis and Treatment
1992 - Lippincott Williams & Wilkins | Hepatology
Aram Hayrapetyan, A. Tumasyan, W. Adam, Janik Walter Andrejkovic, T. Bergauer, S. Chatterjee, K. Damanakis, M. Dragicevic, P. S. Hussain, Manfred Jeitler, N. Krammer, Ang Li, D. Liko, I. Mikulec, J. Schieck, R. Schöfbeck, D. Schwarz, M. Sonawane, S. Templ, W. Waltenberger, C.-E. Wulz, M. R. Darwish, X. Janssen, P. Van Mechelen, E. S. Bols, J. D’Hondt, S. Dansana, A. De Moor, M. Delcourt, H. El Faham, S. Lowette, I. Makarenko, D. Müller, A. R. Sahasransu, S. Tavernier, M. Tytgat, G. P. Van Onsem, S. Van Putte, D. Vannerom, B. Clerbaux, Aloke Kumar Das, G. De Lentdecker, L. Favart, P. Gianneios, D. Hohov, J. Jaramillo, Ali Khalilzadeh, K. Lee, M. Mahdavikhorrami, A. Malara, S. Paredes, Nicolas Postiau, Laurent Thomas, M. Vanden Bemden, Catherine Vander Velde, Pascal Vanlaer, M. De Coen, Didar Dobur, Yanwen Hong, J. Knolle, L. Lambrecht, Gianny Mestdach, K. Mota Amarilo, César Rendón, Amrutha Samalan, K. Skovpen, N. Van Den Bossche, Jan van der Linden, L. Wezenbeek, A. Benecke, A. Bethani, G. Bruno, C. Caputo, C. Delaere, Izzeddin Suat Donertas, A. Giammanco, K. Jaffel, Sandhya Jain, V. Lemaitre, J. Lidrych, Paola Mastrapasqua, Kuntal Mondal, Tu Thong Tran, Sébastien Wertz, G. A. Alves, E. Coelho, C. Hensel, T. Menezes De Oliveira, A. Moraes, P. Rebello Teles, Mariana Soeiro, W. L. Aldá Júnior, M. Alves Gallo Pereira, M. Barroso Ferreira Filho, Helena Brandao Malbouisson, Wagner Carvalho, Jose Chinellato, E. M. Da Costa, G. G. Da Silveira, D. De Jesus Damião, S. Fonseca De Souza, R. Gomes De Souza, J. Martins, C. Mora Herrera, L. Mundim, H. Nogima, Joao Pedro Pinheiro, A. Santoro, A. Sznajder, M. Thiel, A. Vilela Pereira, C. A. Bernardes, L. Calligaris, T. R. Fernandez Perez Tomei, Eduardo De Moraes Gregores, P. G. Mercadante, S. F. Novaes, Breno Orzari, Sandra S. Padula, Aleksandar Aleksandrov, G. Antchev, R. Hadjiiska, P. Iaydjiev, M. Misheva, M. Shopova, G. Sultanov, Anton Dimitrov, L. Litov, B. Pavlov, P. Petkov, A. Petrov, E. Shumka, S. Keshri, S. Thakur, Tongguang Cheng, Tahir Javaid, L. Yuan, Z. Hu, Jinfeng Liu, K. Yi, Guo-Ming Chen, He-Sheng Chen, Mingshui Chen, F. Iemmi, Chun-Hua Jiang, A. Kapoor, H. Liao, Zhenan Liu, R. Sharma, Jia-Ning Song, J. Tao, Chu Wang, Jin Wang, Zebing Wang, Huaqiao Zhang, Antonis Agapitos, Y. Ban, A. Levin, C. Li, Q. Li, Yajun Mao, Si-Jin Qian, Xiaohu Sun, D. Wang, Heng Yang, L. Zhang, C. Zhou, Z. You, N. Lu, G. Bauer, X. Gao, D. Leggat, Hideki Okawa, Z. Lin, C. Lü, Meng Xiao, C. Ávila, Diego Andres Barbosa Trujillo, Andrés Cabrera, C. Florez, J. Fraga, Jose Antonio Reyes Vega, Jhovanny Mejia Guisao, F. Ramirez, M. Rodriguez, J. D. Ruiz Alvarez, D. Giljanovíc, N. Godinović, Damir Lelas, A. Sculac, M. Kovac, T. Sculac, P. Bargassa, V. Brigljević, B. K. Chitroda, D. Ferenček, S. Mishra, A. Starodumov, T. Susa, A. Attikis, K. Christoforou, S. Konstantinou, J. Mousa, C. Nicolaou, F. Ptochos, Panos A Razis, H. Rykaczewski, H. Saka, A. Stepennov, М. Фингер, Michael Finger, A. Kveton, E. Ayala, E. Carrera Jarrin, Ahmed Ali Abdelalim, E. Salama, A. Ahmad, M. A. Mahmoud, K. Ehatäht, M. Kadastik, T. Lange, S. Nandan, C. Nielsen, Joosep Pata, M. Raidal, L. Tani, Christian Veelken, Henning Kirschenmann, K. Österberg, M. Voutilainen, S. Bharthuar, E. Brücken, F. García, Kimmo Tuomas Samuli Kallonen, R. Kinnunen, T. Lampén, K. Lassila-Perini, S. Lehti, T. Lindén, L. Martikainen, M. Myllymäki, Milla-Maarit Rantanen, H. Siikonen, E. Tuominen, J. Tuominiemi, P. Luukka, H. Petrow, M. Besançon, F. Couderc, M. Déjardin, Daniel Denegri, Jean-Louis Faure, F. Ferri, S. Ganjour, P. Gras, G. Hamel de Monchenault, V. Lohezic, Julie Malclès, J. Rander, A. Rosowsky, Mehmet Özgür Sahin, Aurore Savoy-Navarro, P. Simkina, M. Titov, M. Tornago, C. Baldenegro Barrera, F. Beaudette, A. Buchot Perraguin, P. Busson, A. Cappati, C. Charlot, Marco Chiusi, F. Damas, O. Davignon, Adinda De Wit, Bruno Afonso Fontana Santos Alves, Shamik Ghosh, A. Gilbert, R. Granier de Cassagnac, A. Hakimi, B. Harikrishnan, L. Kalipoliti, G. Liu, J. Motta, Matthew Nguyen, C. Ochando, L. Portales, R. Salerno, J. B. Sauvan, Yves Sirois, A. Tarabini, E. Vernazza, A. Zabi, A. Zghiche, J.-L. Agram, J. Andreä,
Abstract A test of lepton flavor universality in B ± → K ± μ + μ − and B ± → K ± e + e − decays, as well as a measurement of differential and integrated branching fractions of a nonresonant B ± → K ± μ + μ − decay are presented. The analysis is made possible by a dedicated data set of proton-proton collisions at s = 13 TeV recorded in 2018, by the CMS experiment at the LHC, using a special high-rate data stream designed for collecting about 10 billion unbiased b hadron decays. The ratio of the branching fractions B ( B ± → K ± μ + μ − ) to ...
IOP Publishing
Аlexander K. Belyaev, Vladimir A. Polyanskiy, D. A. Tretyakov,
Acoustic anisotropy is a consequence of anisotropy of the mechanical characteristics of a solid. In metals, it is associated with microstructural anisotropy of mechanical characteristics, internal mechanical stresses and strains, including residual stresses and plastic deformations. Sensors measuring acoustic anisotropy do not require complex preparations of a metal surface, therefore it is easy to measure which makes it possible for measurement results to be used to quantify stresses and strains ...
Tópico(s): Engineering Diagnostics and Reliability
2020 - | PNRPU Mechanics Bulletin
Dmitry N. Gerasimov, Mikhail E. Belyaev, Vladimir Nikiforov,
The paper addresses the problem of transient performance improvement of direct model reference adaptive control (MRAC) of discrete linear time-invariant (LTI) plants. Two solutions to the problem are proposed and use the certainty equivalence principle and the idea of regressor recording over a past period of time. The first solution is based on the principle of augmented error, while the second one uses new scheme of high order tuner generating predicted values of adjustable parameters. The recording ...
Tópico(s): Control Systems and Identification
2020 - Elsevier BV | European Journal of Control
Аlexander K. Belyaev, Vladimir A. Polyanskiy, A. I. Grishchenko, A.M. Lobachev, D. I. Mansyrev, V.S. Modestov, A. V. Pivkov, А. С. Семенов, L. V. Shtukin, D. A. Tretyakov, Yu. A. Yakovlev,
The article is concerned with the possibilities of the application of the standard method for measuring acoustic anisotropy to the estimation of the degree of plastic deformation. Solutions to the problem of propagation of a sound wave in an isotropic elastic-plastic material are obtained and analyzed. The dependences of the velocity of longitudinal and transverse waves of different polarization on plastic strain are derived. It is shown theoretically and experimentally that the absolute value of ...
Tópico(s): Engineering Diagnostics and Reliability
2016 - American Institute of Physics | AIP conference proceedings
V. M. Kozenkov, V. V. Belyaev, Vladimir G. Chigrinov, Grigoriy Tumovskii, Alexey Spakhov,
Abstract Properties of both amorphous and polycrystal films of azodye AD‐1 have been investigated. The films' structure depends on conditions of thermal treatment, light polarization and intensity. High dichroic ratio (>20) has been obtained. Film structure control allows fabrication of good photoaligning coatings.
Tópico(s): Optical Coatings and Gratings
2012 - Wiley | SID Symposium Digest of Technical Papers
V. D. Belyaev, Vladimir Galvita, В. П. Горелов, V. A. Sobyanin,
Tópico(s): Electronic and Structural Properties of Oxides
1995 - Springer Science+Business Media | Catalysis Letters
Anna M. Varizhuk, Timofei S. Zatsepin, Andrey V. Golovin, Evgeny S. Belyaev, Yury Kostyukevich, Vladimir G. Dedkov, German A. Shipulin, George V. Shpakovski, Andrey V. Aralov,
Nowadays modified oligonucleotides are widely used in diagnostics and as novel therapeutics. Introduction of modified or unnatural residues into oligonucleotides allows fine tuning of their binding properties to complementary nucleic acids and leads to improved stability both in vitro and in vivo. Previously it was demonstrated that insertion of phenoxazine nucleotides with various groups in C9-position into oligonucleotides leads to a significant increase of duplex stability with complementary ...
Tópico(s): RNA Interference and Gene Delivery
2017 - Elsevier BV | Bioorganic & Medicinal Chemistry
Anatoly V. Skalny, Peter Timashev, Michael Aschner, Jan Aaseth, Lyubov N. Chernova, Vladimir E. Belyaev, Andrey R. Grabeklis, Svetlana V. Notova, Ryszard Łobiński, Aristides Tsatsakis, Andrey Svistunov, В. В. Фомин, Alexey A. Tinkov, Petr Glybochko,
The objective of the present study was to evaluate of serum metal levels in COVID-19 patients with different disease severity, and to investigate the independent association between serum metal profile and markers of lung damage. The cohort of COVID-19 patients consisted of groups of subjects with mild, moderate, and severe illness, 50 examinees each. Forty-four healthy subjects of the respective age were involved in the current study as the control group. Serum metal levels were evaluated using ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Multidisciplinary Digital Publishing Institute | Metabolites
Daniel Munblit, Nikita Nekliudov, Polina Bugaeva, Oleg Blyuss, Maria Kislova, Ekaterina Listovskaya, Aysylu Gamirova, Anastasia Shikhaleva, Vladimir E. Belyaev, Peter Timashev, John O. Warner, Pasquale Comberiati, Christian Apfelbacher, Evgenii Bezrukov, Mikhail E. Politov, Andrey Yavorovskiy, E. L. Bulanova, Natalya Tsareva, С. Н. Авдеев, Валентина Капустина, Yu I Pigolkin, Emmanuelle A. Dankwa, Christiana Kartsonaki, Mark G. Pritchard, Victor Fomin, Andrey Svistunov, Denis Butnaru, Petr Glybochko, Anna Berbenyuk, Polina Bobkova, Semyon Bordyugov, Aleksandra Borisenko, Ekaterina Bugaiskaya, Olesya Druzhkova, Д Н Елисеев, Yasmin El-Taravi, Natalia Gorbova, Elizaveta Gribaleva, Rina Grigoryan, Shabnam Ibragimova, Khadizhat Kabieva, Alena Khrapkova, Natalia Kogut, Karina Kovygina, Margaret Kvaratskheliya, Maria Lobova, A. A. Lunicheva, Anastasia Maystrenko, Daria Nikolaeva, Anna Pavlenko, Olga Perekosova, Olga Romanova, Sokova Oi, V S Solovieva, Olga Spasskaya, Ekaterina Spiridonova, Olga Sukhodolskaya, Shakir Suleimanov, Nailya Urmantaeva, Olga Usalka, M. P. Zaikina, Anastasia A. Zorina, Nadezhda Khitrina,
Abstract Background The epidemiology, clinical course, and outcomes of patients with coronavirus disease 2019 (COVID-19) in the Russian population are unknown. Information on the differences between laboratory-confirmed and clinically diagnosed COVID-19 in real-life settings is lacking. Methods We extracted data from the medical records of adult patients who were consecutively admitted for suspected COVID-19 infection in Moscow between 8 April and 28 May 2020. Results Of the 4261 patients hospitalized ...
Tópico(s): COVID-19 and healthcare impacts
2020 - Oxford University Press | Clinical Infectious Diseases
Sergey V. Anisimov, А. Н. Мешков, Аndrey S. Glotov, A. L. Borisova, Oleg Balanovsky, Vladimir E. Belyaev, Oleg Granstrem, Luydmila Yu. Grivtsova, Anastasiya Yu. Efimenko, M. S. Pokrovskaya, Т. А. Семененко, В. С. Сухоруков, А. Д. Каприн, Oxana M. Drapkina,
The research biobanking field is developing rapidly in Russia. Over the course of the last decade, numerous biobanks were created or formed from existing collections of human and environmental biospecimens. The Russian National Association of Biobanks and Biobanking Specialists (NASBIO) was established in December 2018, aiming to: (1) unite professionals and research centers to create and develop a network of biobanks in Russia; (2) provide services and expertise in the field of biobanking; (3) execute ...
Tópico(s): Biomedical Ethics and Regulation
2020 - Mary Ann Liebert, Inc. | Biopreservation and Biobanking
Tópico(s): Dynamics and Control of Mechanical Systems
1990 - Springer Nature | Springer series in nuclear and particle physics
Аlexander K. Belyaev, Vladimir A. Polyanskiy, Yuri A. Yakovlev,
The paper is concerned with study of uncertainties in multi-body systems on example of the hydrogen diffusion. To this end, the distribution of hydrogen due to the diffusion in a system composed from two rods coupled by an imperfect interface is analysed. It is shown that the governing equation for 1-D diffusion is reduced to a generalized Mathieu equation. A closed form expression for the principle instability regions is obtained and a safe level of harmonic load is determined under which the fatigue ...
Tópico(s): Nuclear Materials and Properties
2015 - Elsevier BV | Procedia IUTAM
Marat Akhin, Mikhail Belyaev, Vladimir Itsykson,
Tópico(s): Software Engineering Research
2014 - Pleiades Publishing | Automatic Control and Computer Sciences
Liubov I. Kozlovskaya, Graciela Andreï, Alexey A. Orlov, Evgeny V. Khvatov, Alexander A. Koruchekov, Evgeny S. Belyaev, Е. Н. Николаев, Vladimir A. Korshun, Robert Snoeck, Dmitry I. Osolodkin, Elena S. Matyugina, Andrey V. Aralov,
The phenoxazine scaffold is widely used to stabilize nucleic acid duplexes, as a part of fluorescent probes for the study of nucleic acid structure, recognition, and metabolism, etc. Here we present the synthesis of phenoxazine-based nucleoside derivatives and their antiviral activity against a panel of structurally diverse viruses: enveloped DNA herpesviruses varicella zoster virus (VZV) and human cytomegalovirus, enveloped RNA tick-borne encephalitis virus (TBEV), and non-enveloped RNA enteroviruses. ...
Tópico(s): Adenosine and Purinergic Signaling
2019 - Elsevier BV | Antiviral Research