Аndrey S. Glotov, С. В. Казаков, Елена Жукова, Anton Alexandrov, Oleg S. Glotov, Vladimir S. Pakin, Maria M. Danilova, Irina V. Poliakova, S. S. Niyazova, N. N. Chakova, С. М. Комиссарова, Елена Анатольевна Курникова, Аndrey М. Sarana, Sergey G. Sherbak, Alexey Sergushichev, Anatoly Shalyto, В. С. Баранов,
Hypertrophic cardiomyopathy is a common genetic cardiac disease. Prevention and early diagnosis of this disease are very important. Because of the large number of causative genes and the high rate of mutations involved in the pathogenesis of this disease, traditional methods of early diagnosis are ineffective. We developed a custom AmpliSeq panel for NGS sequencing of the coding sequences of ACTC1, MYBPC3, MYH7, MYL2, MYL3, TNNI3, TNNT2, TPM1, and CASQ2. A genetic analysis of student cohorts (with ...
Tópico(s): Williams Syndrome Research
2015 - Elsevier BV | Clinica Chimica Acta
Daria V. Zhernakova, Vladimir Brukhin, Sergey V. Malov, Tarás K. Oleksyk, Klaus Koepfli, Anna S. Zhuk, Pavel Dobrynin, Sergei Kliver, Nikolay Cherkasov, Gaik Tamazian, Mikhail Rotkevich, Ksenia Krasheninnikova, Igor Evsyukov, Sviatoslav Sidorov, А. В. Горбунова, Ekaterina Chernyaeva, Andrey Shevchenko, Sofia M. Kolchanova, A. S. Komissarov, Serguei Simonov, Alexey Antonik, Anton Logachev, Dmitrii E. Polev, Olga Pavlova, Аndrey S. Glotov, Vladimir Ulantsev, Ekaterina Noskova, Tatyana K. Davydova, Tatyana M. Sivtseva, Limborskaia Sa, Oleg Balanovsky, Vladimir Osakovsky, Alexey Novozhilov, В. П. Пузырев, Stephen J. O’Brien,
The Russian Federation is the largest and one of the most ethnically diverse countries in the world, however no centralized reference database of genetic variation exists to date. Such data are crucial for medical genetics and essential for studying population history. The Genome Russia Project aims at filling this gap by performing whole genome sequencing and analysis of peoples of the Russian Federation. Here we report the characterization of genome-wide variation of 264 healthy adults, including ...
Tópico(s): Genetic Associations and Epidemiology
2019 - Elsevier BV | Genomics
G Thomas, E. D. Williams, Dennis Becker, Bogdanova Ti, Eugene P. Demidchik, E F Lushnikov, Shigenobu Nagataki, В В Остапенко, Aldo Pinchera, G. Souchkevitch, М.D. Тronko, А. Ф. Цыб, Mark S. Tuttle, Shinpei Yamashita,
... Sergey V. Anisimov, Alexey N. Meshkov, Andrey S. Glotov, Anna L. Borisova, Oleg P. Balanovsky, Vladimir E. Belyaev, Oleg K. Granstrem, Luydmila Yu. Grivtsova, ...
Tópico(s): Advances in Oncology and Radiotherapy
2000 - Mary Ann Liebert, Inc. | Thyroid
Аndrey S. Glotov, Evgeny Tiys, Elena S. Vashukova, Vladimir S. Pakin, П. С. Деменков, Olga Saik, Timofey Ivanisenko, Olga N. Arzhanova, Elena V. Mozgovaya, М. С. Зайнулина, Н. А. Колчанов, В. С. Баранов, В. А. Иванисенко,
Pre-eclampsia is the most common complication occurring during pregnancy. In the majority of cases, it is concurrent with other pathologies in a comorbid manner (frequent co-occurrences in patients), such as diabetes mellitus, gestational diabetes and obesity. Providing bronchial asthma, pulmonary tuberculosis, certain neurodegenerative diseases and cancers as examples, we have shown previously that pairs of inversely comorbid pathologies (rare co-occurrences in patients) are more closely related ...
Tópico(s): Cancer-related molecular mechanisms research
2015 - Springer Science+Business Media | BMC Systems Biology
Sergey V. Anisimov, А. Н. Мешков, Аndrey S. Glotov, A. L. Borisova, Oleg Balanovsky, Vladimir E. Belyaev, Oleg Granstrem, Luydmila Yu. Grivtsova, Anastasiya Yu. Efimenko, M. S. Pokrovskaya, Т. А. Семененко, В. С. Сухоруков, А. Д. Каприн, Oxana M. Drapkina,
The research biobanking field is developing rapidly in Russia. Over the course of the last decade, numerous biobanks were created or formed from existing collections of human and environmental biospecimens. The Russian National Association of Biobanks and Biobanking Specialists (NASBIO) was established in December 2018, aiming to: (1) unite professionals and research centers to create and develop a network of biobanks in Russia; (2) provide services and expertise in the field of biobanking; (3) execute ...
Tópico(s): Biomedical Ethics and Regulation
2020 - Mary Ann Liebert, Inc. | Biopreservation and Biobanking
Elena S. Vashukova, Аndrey S. Glotov, PAVEL V. FEDOTOV, Olga A. Efimova, Vladimir S. Pakin, Elena V. Mozgovaya, Anna A. Pendina, Andrei V. Tikhonov, Alla S. Koltsova, В. С. Баранов,
Pre-eclampsia (PE) is a complication of pregnancy that affects 5‑8% of women after 20 weeks of gestation. It is usually diagnosed based on the de novo onset of hypertension and proteinuria. Preexisting hypertension in women developing PE, also known as superimposed PE on chronic hypertension (SPE), leads to elevated risk of maternal and fetal mortality. PE is associated with an altered microRNA (miRNA) expression pattern in the placenta, suggesting that miRNA deregulation is involved in the pathogenesis ...
Tópico(s): Reproductive System and Pregnancy
2016 - Spandidos Publishing | Molecular Medicine Reports
Аndrey S. Glotov, С. В. Казаков, Elena S. Vashukova, Vladimir S. Pakin, Maria M. Danilova, Yulia A. Nasykhova, Aleksey E. Masharsky, Elena V. Mozgovaya, Д. Р. Еремеева, Marina S. Zainullina, В. С. Баранов,
Background: Preeclampsia (PE) is the most common complication of pregnancy that remains to be a major cause of maternal and fetal mortality. Prediction and early diagnosis of PE would allow for timely initiation of preventive therapy. According to recent studies of ACVR2A gene polymorphism is associated with PE, but it is still unclear whether these findings reflect specific pathogenetic mechanisms of this disease. Methods: We performed targeted next-generation sequencing (NGS) sequencing of ACVR2A ...
Tópico(s): MicroRNA in disease regulation
2018 - Informa | The Journal of Maternal-Fetal & Neonatal Medicine
Н Н Воробьева, М Г Галушкин, E. P. Glotov, V G Lyakishev, Vladimir Rodionov, Aleksandr M Seregin, N V Cheburkin, S K Chekin,
A theoretical analysis is made of some features of the emission spectra of high-pressure CO2 lasers. Dependences of their spectral characteristics on the main parameters of lasers utilizing 12CO2 and 13CO2 molecules are determined. It is shown that simultaneous lasing due to several transitions is typically found for pulses of ≲ 1 μsec duration, whereas single-frequency lasing due to the P(20) transition for 12CO2 and due to the P(16) transition for 13CO2 may occur for longer pulses.
Tópico(s): Diamond and Carbon-based Materials Research
1984 - IOP Publishing | Soviet Journal of Quantum Electronics
R. B. Samsonov, Tatiana Shtam, Vladimir Burdakov, Аndrey S. Glotov, Е. V. Tsyrlina, Lev M. Berstein, А. К. Носов, В И Евтушенко, Filatov Mv, Anastasia Malek,
BACKGROUND Prostate cancer is the most common cancer in men. Prostate‐specific antigen has, however, insufficient diagnostic specificity. Novel complementary diagnostic approaches are greatly needed. MiRNAs are small regulatory RNAs which play an important role in tumorogenesis and are being investigated as a cancer biomarker. In addition to their intracellular regulatory functions, miRNAs are secreted into the extracellular space and can be found in various body fluids, including urine. The stability ...
Tópico(s): Circular RNAs in diseases
2015 - Wiley | The Prostate
Oleg V. Goloshchapov, Evgeny Bakin, M. A. Kucher, Oksana V. Stanevich, Maria Suvorova, Vladimir Gostev, Oleg S. Glotov, Yury A. Eismont, Dmitrii E. Polev, Anastasia Yu. Lobenskaya, Ruslana V. Klementeva, Мaria О. Goloshchapova, L. S. Zubarovskaya, Sidorenko Sv, А. Н. Суворов, Ivan Moiseev, Alexei B. Chukhlovin,
Summary Fecal microbiota transplantation (FMT), as any other medical procedure, requires standardization of results, approaches, monitoring of its dynamics and microbiota engraftment evaluation. The aim of the present study was to compare efficiency and results of PCR and 16S RNA-based sequencing in order to trace the dynamics of microbiota composition after FMT. Patients and methods The prospective, single-center study included 27 patients with acute intestinal and chronic (overlap syndrome) graft- ...
Tópico(s): Neutropenia and Cancer Infections
2020 - Hamburg University Press | Cellular Therapy and Transplantation
G. O. Zasypalov, А. В. Вутолкина, Vladimir Klimovsky, Egor Abramov, В. А. Винокуров, А. P. Glotov,
Halloysite nanotubes (HNTs) is a promising support for liquid-phase hydrodeoxygenation (HDO) catalysts due to a wide abundance, low cost and tunable properties. Acid etching of halloysite by sulfuric acid was found to enlarge lumen diameter (24.3 nm), enhance specific surface area (154 m2/g) and acidity (0.343 mmol/g). Based on pristine and dealuminated HNTs, Ru-containing catalysts were synthesized via impregnation under microwave irradiation. The catalytic properties of synthesized catalysts in HDO ...
Tópico(s): Iron oxide chemistry and applications
2023 - Elsevier BV | Applied Catalysis B Environment and Energy
Yury A. Barbitoff, D. N. Khmelkova, Ekaterina Pomerantseva, Aleksandr V. Slepchenkov, Nikita A. Zubashenko, И. В. Миронова, Vladimir Kaimonov, Dmitrii E. Polev, Victoria V. Tsay, Аndrey S. Glotov, М. В. Асеев, Sergey Shcherbak, Oleg S. Glotov, А. А. Исаев, Alexander V. Predeus,
ABSTRACT Population allele frequency is crucially important for accurate interpretation of known and novel variants in medical genetics. Recently, several large allele frequency databases, such as the Genome Aggregation Database (gnomAD), have been created to serve as a global reference for such studies. However, frequencies of many rare alleles vary dramatically between populations, and population-specific allele frequency is often more informative than the global one. Many countries and regions, ...
Tópico(s): Forensic and Genetic Research
2024 - Oxford University Press | National Science Review
Oleg S. Glotov, Аndrey S. Glotov, Vladimir S. Pakin, В. С. Баранов,
Theoretical and practical aspects of complex health monitoring of man are reviewed. Health monitoring includes comparison of genetic testing results with the relevant physical features, life history data, present mode of life and the results of standard laboratory analysis. The history of origin and progression of sport genetics, its main directions, and the problems of genetic risk is briefly outlined. Options, indications and restrictions of genetic testing for prevention of monogene disorders ...
Tópico(s): Human Health and Disease
2013 - Saint Petersburg State University | Biological Communications
А. В. Вутолкина, G. O. Zasypalov, Yamen Aljajan, Vladimir Klimovsky, В. А. Винокуров, Maria Rubtsova, А. А. Pimerzin, А. P. Glotov,
Effective and low-cost gram-scale Ru-containing catalysts for removal of aromatics from the gasoline fraction while retaining the octane number.
Tópico(s): Zeolite Catalysis and Synthesis
2023 - Royal Society of Chemistry | New Journal of Chemistry
Аndrey S. Glotov, Elena S. Vashukova, Maria D Kanaeva, Maria O Dvoeglazova, Maria M. Danilova, Vladimir S. Pakin, Ekaterina Yu Marochkina, Dina Rustemovna Bicmullina, Maria A Glebova, Ирина Александровна Махрова, Г. И. Образцова, Oleg S. Glotov, М. С. Зайнулина, Tatyana E Ivashchenko, В. С. Баранов,
Polymorphisms of APOE (E2/E3/E4), LPL (1595CG) and NOS3 (-786TC) in groups of pregnant women with and without preeclampsia, in donors, in children with hypertension, children with obesity and metabolic syndrome, and in control children were studied by PCR /RF LP analysis. Statistically significant increase of T/C genotype frequency of NOS3 in pregnant women with preeclampsia as well as in women with physiological pregnancy compared to this one in nonpregnant women of donors group was assessed (56%, 59% ...
Tópico(s): Gestational Diabetes Research and Management
2011 - | Ecological genetics
Generalov Alexander, G Glotov Oleg, A Arkhipov Vladimir, E Zarko Vladimir, B Kiskin Alexander,
2017 - Elsevier BV | Combustion and Flame
С. А. Федотов, М. С. Храброва, Elena S. Vashukova, Аndrey S. Glotov, Anastasiia Anpilova, Vladimir Dobronravov, M. E. Velizhanina, Aleksandr A. Rubel,
Preeclampsia is a disorder that can occur during pregnancy and is one of the leading causes of death among pregnant women. This disorder occurs after the 20th week of pregnancy and is characterized by arterial hypertension, proteinuria, fetoplacental, and multiple organ dysfunctions. Despite the long history of studying preeclampsia, its etiology and pathogenesis remain poorly understood, and therapy is symptomatic. One of the factors of the disorder is believed to be misfolded proteins that are ...
Tópico(s): Pregnancy and Medication Impact
2024 - Public Library of Science | PLoS ONE
К. А. Титова, А. А. Сергеев, А. С. Кабанов, Bulychev Le, Ар. А. Сергеев, Д. О. Галахова, Shishkina Ln, A. S. Zamedyanskaya, А. Е. Нестеров, A.G. Glotov, О. С. Таранов, Vladimir V. Omigov, А. П. Агафонов, Sergeev An,
Mice of the ICR outbred population were infected intranasally (i/n) with the variola virus (VARV, strain Ind-3a). Clinical signs of the disease did not appear even at the maximum possible dose of the virus 5.2 lg PFU/head (plaque-forming units per head). In this case, 50% infective dose (ID50) of VARV estimated by the presence or absence of the virus in the lungs three days after infection (p.i.) was equal to 2.7 ± 0.4 lg PFU/head. Taking into account the 10% application of the virus in the lungs during ...
Tópico(s): Plant Virus Research Studies
2016 - Central Research Institute for Epidemiology | Problems of Virology
Y. V. Gomeniuk, Y. Y. Gomeniuk, Tamara Rudenko, P. N. Okholin, Volodymyr I. Glotov, Tamara M. Nazarova, Vladimir Djara, K. Cherkaoui, Paul K. Hurley, A. N. Nazarov,
In this paper, we study the effect of low-temperature RF plasma treatment in forming gas (10%H2+90%N2) on the electrical characteristics of junctionless MOSFETs with n-In0.53Ga0.47As channel and an Al2O3 gate dielectric. The impact of plasma power density on the device parameters is investigated. It is found that RF plasma annealing with a low power density (0.5 W/cm2) at 150°C for 10 min provides substantial improvement of source/drain contacts resistance and the carrier mobility resulting in a considerable ...
Tópico(s): Advancements in Semiconductor Devices and Circuit Design
2019 - Institute of Physics | ECS Journal of Solid State Science and Technology
Vladimir S. Pakin, Elena S. Vashukova, Roman V. Kapustin, Olga N. Arzhanova, Аndrey S. Glotov, В. С. Баранов,
The aim of study was to determine feasible changes of placental miRNAs expression profiles revealed by next generation sequencing (NGS) in pregnancies with GDM complicated or not with PE. Out of 27 miRNAs, studied expression was significantly different (FDR < 0.05) only for his-miR-45a. Comparative analysis of revealed reliable differences in expression of hsa-miR-4532 (p < 0.0001, FDR = 0.0008), hsa-miR-34c-5p (p < 0.0001, FDR = 0.0083), and hsa-miR-193b-5p (p < 0.0001, FDR = 0.0139) in pregnancy complicated by PE, ...
Tópico(s): Cancer-related molecular mechanisms research
2017 - ECO-vector | Journal of obstetrics and women s diseases
N. D. Ustinov, A. I. Avrov, E. P. Glotov, V. N. Koterov, A. G. Krasnovskii, Vladimir Prigarin, A. M. Soroka, N V Cheburkin,
Tópico(s): Advanced Fiber Laser Technologies
1985 - Springer Science+Business Media | Soviet physics. Doklady
G. O. Zasypalov, Vladimir Klimovsky, Egor Abramov, E. E. Brindukova, V. D. Stytsenko, А. P. Glotov,
Tópico(s): Biofuel production and bioconversion
2023 - Pleiades Publishing | Petroleum Chemistry
Yu. Byalovsky, S. V. Bulatetsky, V. A. Kiryushin, Н. И. Прохоров, Vladimir Abrosimov, S. I. Glotov, Irina Ponomareva, S. V. Subbotin,
The aim of the study was to evaluate the effect of the duration of training on the use of personal respiratory protective equipment on indices of pulmonary gas exchange. Simulation of conditions for the use of personal respiratory protective equipment was carried out at the inspiratory resistance of 40, 60, 70 and 80% Pmmax. The study included 38 healthy male subjects aged 20 to 36 years. According to the results of the study, under the use of personal protective equipment for the respiratory system, ...
Tópico(s): Chemical and Physical Studies
2018 - Meditsina | Hygiene and Sanitation
... the voyages of Aleksey I. Timashev and Gavriil Glotov from the newly founded naval bases in the ...
Tópico(s): Marine and environmental studies
2000 - Taylor & Francis | Imago Mundi
С. А. Федотов, Elizaveta Gerasimova, Elena S. Vashukova, Vladimir S. Pakin, Roman V. Kapustin, Olga V. Pachuliia, Аndrey S. Glotov, Konstantin Yu. Kulichikhin, Yury O. Chernoff, Aleksandr A. Rubel,
BACKGROUND: Preeclampsia is a multisystem complication of pregnancy associated with an increased risk of maternal / perinatal morbidity and mortality. In this regard, the development and following improvement of low-cost and convenient methods for diagnosis of preeclampsia is essential for accurate prediction, quick confirmation of the diagnosis and convenient monitoring of the pathology. AIM: The aim of this study was to optimize a preeclampsia diagnosis test system based on the binding of proteins ...
Tópico(s): Neonatal Respiratory Health Research
2022 - ECO-vector | Journal of obstetrics and women s diseases
pYuri Lvov Weimin Du Vladimir Vinokurov Anna Stavitskaya Alex, r Glotov, Andrei Novikovp,
Tópico(s): Iron oxide chemistry and applications
2019 - OMICS Publishing Group | Journal of Material Science & Engineering
G. O. Zasypalov, А. В. Вутолкина, А. А. Pimerzin, Vladimir Klimovsky, Egor Abramov, А. P. Glotov,
Tópico(s): Iron oxide chemistry and applications
2024 - Elsevier BV | Applied Clay Science
Produção Nacional
Revisado por pares
Yelena Kukhar, Vladimir Kiyan, Т.I. Glotova, A.G. Glotov,
Long-term studies (2012–2018) of cultures of microscopic fungi (dermatomycetes) isolated from clinically sick cats were carried out. Samples of biomaterial were taken from domestic animals with signs of skin and coat damage in veterinary clinics of the Republic of Kazakhstan. Molecular genetic studies, species identification and determination of the properties of selected cultures were carried out in accordance with the approved methodological recommendations and with the use of determinants of pathogenic ...
Tópico(s): Antifungal resistance and susceptibility
2020 - | Siberian Herald of Agricultural Science
Аndrey S. Glotov, Elena S. Vashukova, Oleg S. Glotov, Roman Vladimirovich Kurilov, Irina V Tarkovskaia, Ekaterina Y Ditkina, Irina V Pugacheva, Olga L Belonog, Ирина Александровна Махрова, Vladimir S. Pakin, М. В. Асеев, Т. Э. Иващенко,
A population study of polymorphisms of EFEMP1, ZBTB38, HHIP, LCORL, ADAMTSL3, CDH13, JAZF1, IGF1R, GHSR, CABLES1, IFNG, VDR3, and IGFBP3 genes, which possibly influence human height, was carried out using PCR-RFLP. Population frequencies of alleles and genotypes for these genes were established. A correlation between the rs572169 variant of GSHR gene and male height was found . We suggest a model for prediction of human height on the basis of logistic regression method. The obtained data indicate ...
Tópico(s): Biomarkers in Disease Mechanisms
2012 - | Ecological genetics
Аndrey S. Glotov, Elena S. Vashukova, Oleg S. Glotov, Roman Vladimirovich Kurilov, I. V. Tarkovskaya, Ekaterina Y Ditkina, Irina V Pugacheva, Olga L Belonog, Ирина Александровна Махрова, Vladimir S. Pakin, М. В. Асеев, Т. Э. Иващенко,
Tópico(s): Genetic Mapping and Diversity in Plants and Animals
2014 - Springer Nature | Russian Journal of Genetics Applied Research