Martijn W. H. Pinkse, Dirk T. S. Rijkers, Wolfgang R. Dostmann, Albert J. R. Heck,
... a construct of a PKG tight binding sequence (W45, LRKKKKKH, KI = 0.8 μm) and a membrane ... ATP binding. By analogy, the individual inhibitor peptides W45 and DT-6 were also found to cross- ... of the inhibitor peptides. Dimeric PKG binds two W45 and DT-6 peptides, whereas only one DT- ... a construct of a PKG tight binding sequence (W45, LRKKKKKH, KI = 0.8 μm) and a membrane ... ATP binding. By analogy, the individual inhibitor peptides W45 and DT-6 were also found to cross- ... of the inhibitor peptides. Dimeric PKG binds two W45 and DT-6 peptides, whereas only one DT- ...
Tópico(s): Pharmacogenetics and Drug Metabolism
2009 - Elsevier BV | Journal of Biological Chemistry
Marcela Capcarová, L. Chmelnicna, Adriana Kolesárová, Péter Massányi, Jaroslav Kováčik,
... period at 5 (w5), 25 (w25) and 45 (w45) weeks of production. Body weight, rate of lay ... found in the experimental group at w5 and w45. Concentrations of inorganic phosphorus in the experimental group ... significantly higher at w25, but significantly lower at w45. Erythrocyte count was significantly higher in the experimental group at w25 and w45 when compared with controls. Leucocyte counts were significantly ... Significantly lower values of haematocrit at w5 and w45 were observed in the experimental group than in ...
Tópico(s): Meat and Animal Product Quality
2010 - Taylor & Francis | British Poultry Science
Krzysztof Buśko, A. Madej, Аndrzej Mastalerz,
... equal 45 kJ, pedalling rate – 80 rpm; group W45 – 3min efforts with the power of 250 W, ... Four week training elicited in groups M10, M5, W45 and W45 significant increase of the maximal (except group W45 where it was unimportant) and average power and, ... centre lift in CMJ jump: crucial in groups W45 (-4.7%) and W80 (-4.7%) and not ...
Tópico(s): Sports and Physical Education Research
2010 - Termedia Publishing House | Biology of Sport
Wolfgang R. Dostmann, Werner Tegge, Ronald Frank, Christian K. Nickl, Mark Taylor, Joseph E. Brayden,
... library arrays on paper identified the sequence LRK5H (W45). Binding of W45 to cGPK resulted in selective inhibition of the ... and cAPK, respectively. Cellular internalization of highly charged W45 was accomplished by N-terminal fusion of membrane ... Ki values 40- to 80-fold lower than W45. Fluorescein-labeled DT-2 and DT-3 demonstrated ...
Tópico(s): Cell Adhesion Molecules Research
2002 - Elsevier BV | Pharmacology & Therapeutics
Junjie Tong, Peter J. Minogue, Wenji Guo, Tung-Ling Chen, Eric C. Beyer, Viviana M. Berthoud, Lisa Ebihara,
... the first extracellular boundary in human connexin50 (Cx50), W45S and G46V. Both of these mutants formed gap ... Dual two-microelectrode voltage-clamp studies showed that W45S did not form functional intercellular channels in paired ... oocytes or hemichannel currents in single oocytes. When W45S was coexpressed with wild-type Cx50, the mutant ... connexin function and cause disease by different mechanisms: W45S inhibits gap junctional channel function; G46V reduces cell ...
Tópico(s): Yersinia bacterium, plague, ectoparasites research
2011 - American Physical Society | AJP Cell Physiology
Wolfgang R. Dostmann, Mark Taylor, Christian K. Nickl, Joseph E. Brayden, Ronald Frank, Werner Tegge,
... the peptides identified the sequence LRK 5 H (W45) as having the highest binding affinity. Binding of W45 to cGPK resulted in selective inhibition of the ... cAMP-dependent protein kinase (cAPK), respectively. Fusion of W45 to membrane translocation signals from HIV-1 tat ... fusion peptides was even greater than that for W45, with K i values of 12.5 nM ...
Tópico(s): Signaling Pathways in Disease
2000 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Steven Jacobs, Sean D. Taverna, Yinong Zhang, Scott Briggs, Jin Li, Joel C. Eissenberg, C. David Allis, Sepideh Khorasanizadeh,
... is formed by conserved hydrophobic residues L43 and W45. In addition, the electrostatic charge distribution at the ... surrounded by highly conserved residues Y24, V26, L43, W45 and C63, coincides with the NMR-detected site ... These may form favorable interactions near the L43/W45 dip of the chromo domain. Methyl-K9 and ... in (C) are labeled. In addition, residues L43, W45 and E56 were labeled in the putative binding ...
Tópico(s): Ubiquitin and proteasome pathways
2001 - Springer Nature | The EMBO Journal
Huiling Mao, Yanfang Zhang, Yan Yun, Wenwen Ji, Zhao Jin, Chong Wang, Zhongtang Yu,
... a group weaned at 45 days of age (W45), with each group having five replicate pens. On ... day 30 for W30 and day 45 for W45) and at 5 days postweaning [day 35 for W30 (PW30) and day 50 for W45 (PW45)], one lamb from each replicate was randomly ... At genus level, the extended milk replacer feeding (W45 vs. W30) increased the relative abundance of Ruminococcus ...
Tópico(s): Gut microbiota and health
2021 - Frontiers Media | Frontiers in Microbiology
Franz Hofmann, Wolfgang R. Dostmann, Alexandra Keilbach, Wolfgang Landgraf, Peter Ruth,
... a construct of a PKG tight binding sequence (W45, LRKKKKKH, KI = 0.8 μm) and a membrane ... ATP binding. By analogy, the individual inhibitor peptides W45 and DT-6 were also found to cross- ... of the inhibitor peptides. Dimeric PKG binds two W45 and DT-6 peptides, whereas only one DT- ...
Tópico(s): Phosphodiesterase function and regulation
1992 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
... have investigated dielectronic recombination (DR) for Cu-like W45+ forming Zn-like W44+ by theoretical calculation using ... 50% at 2–7 keV energy range where W45+ is abundant.
Tópico(s): Muon and positron interactions and applications
2015 - Elsevier BV | Journal of Quantitative Spectroscopy and Radiative Transfer
Qingchuan Zou, Wu Da, Xizhong An, Meng Li, Changyuan Xu, Xianglin Zhou, Jinchuan Jie, Zonghui Dong,
... the peaked uniformity can reach 0.986. The (W45–20Cu30)-20(W10–20Cu10) size ratio in ternary ... component system. The relative density of best ternary (W45–20Cu30)-20(W10–20Cu10) system can reach 0. ... was 10.7% higher than that of binary W45–20Cu30 system. In the best packing structure with ...
Tópico(s): Fusion materials and technologies
2022 - Elsevier BV | Journal of Materials Research and Technology
Xiaobin Ding, Peng Yang, Guoding Zhang, Maogen Su, Ling Zhang, Yang Yang, Ke Yao, Yunqing Fu, Chenzhong Dong,
The wavelength and transition rates of W43+-W45+ ions in the 40-140 Å region have been calculated by the relativistic configuration interaction method with the implementation of the Flexible Atomic ... spectrum from the collisional-radiative model of W43+-W45+ ions agreed with the Tokamak plasma spectrum. Some strong emission lines of the W43+-W45+ ions are identified and assigned in the present ...
Tópico(s): Laser-induced spectroscopy and plasma
2021 - Elsevier BV | Physics Letters A
Satoshi IWAKIRI, Mitsuo Inayama,
... φr=90°(E-W), φr=45°(E45°N-W45°S), and °r=135°(E45°S-W45°N). It is assumed in the calculations that ...
Tópico(s): Remote Sensing in Agriculture
1974 - Society of Agricultural Meteorology of Japan | Journal of Agricultural Meteorology
Yi Li, Dimitri Y. Chirgadze, Victor M. Bolaños-García, B. L. Sibanda, Owen R. Davies, Peter Ahnesorg, Stephen P. Jackson, Tom L. Blundell,
... well, and α-helices are in similar orientations. W45 and W119 are found at the topologically equivalent ... αD1, and the two motifs superpose well. Remarkably, W45 of β4 and W119 of β7 are structurally ...
Tópico(s): Neonatal Health and Biochemistry
2007 - Springer Nature | The EMBO Journal
... radiatively damped R-matrix calculations for W44+ and W45+. Radiation damping is found to be small for W45+, but is appreciable for many of the excitations ...
Tópico(s): Nuclear physics research studies
2007 - IOP Publishing | Journal of Physics B Atomic Molecular and Optical Physics
Belinda L. Dias-Kadambi, Kelly A. Combs, Chester L. Drum, Dorothy A. Hanck, Kenneth M. Blumenthal,
... This effect is also observed for W45A and W45S in the cardiac model, wherein W45F is normal. ... This effect is also observed for W45A and W45S in the cardiac model, wherein W45F is normal. ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
1996 - Elsevier BV | Journal of Biological Chemistry
Freddie W. West, Han‐Seok Seo, Thomas D. Bradrick, Elizabeth E. Howell,
... W338) occur at the dimer−dimer interfaces, while W45 and its symmetry-related partners (W145, W245, and ... less stable than the environment monitored by the W45 residue.
Tópico(s): Enzyme Structure and Function
2000 - American Chemical Society | Biochemistry
Ling Zhang, S. Morita, Zhenwei Wu, Zong Xu, Xiuda Yang, Yunxin Cheng, Qing Zang, Haiqing Liu, Yong Liu, Hongming Zhang, T. Ohishi, Yingjie Chen, Liqing Xu, Chengrui Wu, Yanmin Duan, Wei Gao, J. Huang, Xianzu Gong, Liqun Hu,
... radial profiles of tungsten line emissions from W42+ – W45+ ions with 4p–4s transitions measured at two ... The result shows that the density of W43+ – W45+ ions ranges at 2–6 × 108 cm−3 ...
Tópico(s): Laser-Plasma Interactions and Diagnostics
2018 - Elsevier BV | Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment
Zhe Chen, Shidong Ge, Zhenhua Zhang, Yangong Du, Buqing Yao, Huichun Xie, Pan Liu, Yufang Zhang, Wenying Wang, Huakun Zhou,
... volumetric water contents (VWC, W15-15%, W30-30%, W45-45%) under 165 F-T cycles in topsoil ( ... treatments, on the contrary, the cumulative emissions of W45 treatments slowly increased until more than 80 cycles. ...
Tópico(s): Peatlands and Wetlands Ecology
2021 - Frontiers Media | Frontiers in Ecology and Evolution
E. Liokati, A. Nindos, Y. Liu,
... they reach heliographic longitude of 45$^{\circ}$ West (W45). Results. Seven of the ARs produced CMEs while ... the AR produces its first CME or crosses W45, whichever happens first. We found magnetic helicity and ...
Tópico(s): Geomagnetism and Paleomagnetism Studies
2022 - EDP Sciences | Astronomy and Astrophysics
Roger Chou, Tracy Dana, Shelley Selph, Annette M Totten, David Buckley, Rongwei Fu,
... General Population April 2021Volume 174, Issue 4 Page: W45-W46 Keywords COVID-19 Epidemiology Health care providers ...
Tópico(s): COVID-19 epidemiological studies
2021 - American College of Physicians | Annals of Internal Medicine
Runjia Bao, Junkui Wei, Bowen Li, Ximeng Chen,
... sections for tungsten ions, spanning charge states W38+− W45+. The level-to-level distorted-wave method implemented ... configuration-averaged calculations has been performed for the W45+ ion, and we explore the possible reason for ... Present calculations provide missing cross-sections for W38+− W45+. The data obtained are expected to be useful ...
Tópico(s): Plasma Diagnostics and Applications
2022 - Multidisciplinary Digital Publishing Institute | Atoms
... nonterminating well-poised ϕ23, nonterminating very-well-poised W45, W78, products of two nonterminating ϕ12's, square ...
Tópico(s): Religion and Sociopolitical Dynamics in Nigeria
1982 - Elsevier BV | Journal of Mathematical Analysis and Applications
... Nd31+, Sm33+, Gd35+, Dy37+, Er39+, Yb41+, Ta44+, and W45+ have been observed with a laser-produced plasma ...
Tópico(s): Laser-induced spectroscopy and plasma
1981 - IOP Publishing | Physica Scripta
Reactions of thin Co55 W45 films in contact with Si(100) substrates and aluminum overlayers annealed in vacuum in the temperature ranges of 625–700 ° ...
Tópico(s): Advanced ceramic materials synthesis
1989 - American Institute of Physics | Journal of Applied Physics
Ethan A. Smith, Ruth C. Carlos, Larry Junck, Christina Tsien, Augusto Elias, Pia C. Sundgren,
Differentiation between recurrent neoplasm and postradiation change in patients previously treated for primary brain tumors is often difficult based on imaging features alone. The purpose of this study was to develop a method using alterations in the ratios of standard brain metabolites-choline (Cho), creatine (Cr), and N-acetylaspartate (NAA)-to predict the probability of tumor recurrence in patients previously treated for brain tumors with new contrast-enhancing lesions.Thirty-three patients who ...
Tópico(s): MRI in cancer diagnosis
2009 - American Roentgen Ray Society | American Journal of Roentgenology
Emmanuel O. Akala, Adesoji R Adedoyin, Festus A. Ogunbona,
... gelatin) and water miscible synthetic fatty base (Witepsol W45) are superior to natural fatty bases (theobroma oil ...
Tópico(s): Pharmacology and Obesity Treatment
1991 - Taylor & Francis | Drug Development and Industrial Pharmacy
Roger J. Thomas, W. M. Neupert,
... cutting through the center of AR5464 at S18 W45. Wavelength coverage is 170-450 A with a ...
Tópico(s): Atmospheric Ozone and Climate
1994 - Institute of Physics | The Astrophysical Journal Supplement Series
Jizhen Wang, Jayita Sen, Lijun Rong, Michael Caffrey,
... 2119-2123Crossref PubMed Google Scholar) found that mutant W45S reduced processing and gp120 association with gp41. In ...
Tópico(s): HIV/AIDS Research and Interventions
2008 - Elsevier BV | Journal of Biological Chemistry
Raffaello Potestio, T. Aleksiev, Francesco Pontiggia, Stefano Cozzini, Cristian Micheletti,
The ALADYN web server aligns pairs of protein structures by comparing their internal dynamics and detecting regions that sustain similar large-scale movements. The latter often accompany functional conformational changes in proteins and enzymes. The ALADYN dynamics-based alignment can therefore highlight functionally-oriented correspondences that could be more elusive to sequence- or structure-based comparisons. The ALADYN server takes the structure files of the two proteins as input. The optimal ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2010 - Oxford University Press | Nucleic Acids Research