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Jonathan Northcroft, Kevin Dunn, Waldemar Januszczak, John Dugdale, Steve Pittard, Matthew Wall, Helena Frith Powell, Barbara Hall, Peter J Hegarty, Johnny Davis, N J, Fred Redwood, S R, Jim Munro, Peter Whittle, Helen Davies, David Mills, Sally Brock, Nicholas Rufford, John Peter, Professor Gideon Garter, Amanda Ursell, William Lewis Business Editor, George Austen, Andrew Longmore, Bill Wigmore, Simon Forrester, Adam Hathaway, P H, Susan d'Arcy, Frank Whitford, Ivo Tennant, Colonel Tim Collins, Dennis Pallis, David Carcknell Political Editor, Kathryn Cooper, Sam Gilpin, William Lewis, David Smith, Stella Chaplin, Prince Harry, Des Kelly, Neil Wormald, E P, Andrew Sullivan, Alison Kervin, Amanda McCarthy, Jacqueline Grace, Stephen Grey, K R, Karen Robinson, Clive Davis, A C, Tony Allen-Mills, Susan Berger, Norman Cook, Robert Sandall, Martin James, Anthony Sattin, Robert Winnett, Alan Ward, Dipesh Gadher Transport Correspondent, Irwin Stelzer, Duncan Farmer, Tom English, Adrian Furnham, Rosie Millard, Peter Wilson, Robert Hewison, David Dougill, John Arlidge, Clive Smith, Anna Bruning, David Hewson, Ian Edward, Robert Katz, Cally Law, Hugh Canning, Geraldine Hackett Education Correspondent, Mike Pattenden, Jeremy Clarkson, Victoria Segal, Edward Porter, Peter Conradi, David Cairns, Nicola Smith, Dispesh Gadher Transport Correspondent, Michael Portillo, Basil D'Oliveira, Stewart Lee, Patricia Nicol, Anthony Peregrine, Dave Pollard, Christopher Price, Pelle Neroth, Richard Fletcher, Stella Tillyard, Simon Marshall, Simon Rogerson, C C, L E, Rupert Wright, Andrew Porter Deputy Political Editor, Jeremy Guscott, Paul Bailey, Holly Watt, Andrew Thomas, Talib Choudhry, Paul Abdale, Peter Parker, Mike Laws, Robin Scott-Elliot, Stuart Wavell, Sarah-Kate Templeton, Roger Eglin, Christopher Silvester, Ali Rifat, Donald Carr, Pat Cash, Lynn Eaton, Vincent Crump, Michael Cole, Simon Mills, Chris Woodhead, Monsieur Mangetout, Jasper Gerard, Paul Driver, John Humphrys, Nicholas Hellen, Richard Brooks, John Follain, Ruth Rose, Minette Marria, Ian Hawkey, Alex Clark, Madonna, David Leppard, Paul Durman, Claire Tomalin, Lisa Grainger, Jonathon Carr-Brown Health Correspondent, Mark Edwards, J Crane, Susan Clark, Askold Krushelnycky, John Pullinger Director, Robert Lacey, Steve Moxon, Msgr Stephen Louden, Lois Rogers, Sean Newsom, James Bradley, Raymond Keene, Gareth Huw Davies, Rod Liddle, Cosmo Landesman, Zoe Brennan, Diana Wright, Jay Leno, Jesse Crosse, Emma Smith, David Willetts, Helen Hawkins, Stephen Jones, Dominic O'Connell, Stephen Bleach, Barry Flatman, Uzi Mahnaimi, Nick Cain, Peter Brooks, Louise Armitstead, Michael Wright, Natalie Graham, Amanda Blinkhorn, Peter Watson, Caroline Donald, Nick Rennison, Miranda Seymour, David Walsh, Maarten Krabbendam, Graham Norwood, Marc Padgett, Helen Brown, Tom Norrington-Davies, Trevor Lewis, Jo Foley, Gareth Southgate, Bryan Appleyard, Pat Hagan, Edward Porger, Colin McDowell, Stephen Armstrong, John Elliott, Dr Stevie Davies, Colin McDowell's, Christopher Goodwin, Bethan Cole, Victoria O'brien, Jonathan Leake Environment Editor, Richard Woods, Roland White, Danny Roth, Marcus Brooks, Shane Watson, Richard Brooks Arts Editor, Philip Marsh, Yuba Bessaoud, Richard Rae, Mark Franchetti, Dave Hanningan, Ray Hutton, Jon Ungoed-Thomas, Kathryn Blundell, David Cracknell Polical Editor, Susan Hampshire, Michael Sheridan, D J Taylor, John Harlow, Dileep Premachandran, Peter Bowles, Brian Smyth, A B, Ben Hall, Hunter Davies, John Waples, K Smyth, A A Gill, Donald Ross, A M C, Matthew Campbell, Brian Glanville, John Carey, David Craik, Adam Hildreth, Tom Robbins, Don Lewin founder of Clinton Cards, Mary Braid, Minty Clinch, Jason Mellor, Jonathan Carr-Brown, Will Iredale, B Josephs, Jonathan Leake Science Correspondent, Jessica Bown, Stephen Pettitt, T L, Sally Kinnes, Angus McCrone, Naomi Caine, Nigel Powell, Ann Maurice, Roger Dobson, Peter Almond, Heather Ewing, Brian Doogan, Ben Dowell, John Aizlewood, Jeremy Lazell, Llam Clarke, Mark Hodson, Mike Gatting, Simon Kurs, Ian Kell, Joe Lovejoy, Sarah-Kate, Jonathan Futrell, Andrew Frankel, David Budworth, Anthony Bourdain, Hugh Pearman, Dan Cairns, Olivger Bennett, Pete Oliver, Christopher Bray, John Cornwell, Stewart Mitchell, Rachel De Thame, R D, Shelley Von Strunckee, Sarah Baxter, Brian Schofield, Ben Axford, James Willoughby, Joanna Simon, Matthew Goodman, India Knight, Howard Wallace-Sims, Idris Francis, Fiona Henderson, Sandy Gall, Rubens Barrichello, Ed Hughes, Simon Howard, Barry Newcombe, Dominic Rushe, Carol Cooper, Jamison MacLachlan, Colin Hide, Helen Stewart,

... Plant Life New kids in town Perfect pitch Willie Nelson Drive by Truckers Various Artists Albert Ayler ... World Order Renault Mecane Shaun Allan and Csilla de Bagota Andalusia BT The Hunter Coxes Volterra, Tuscany ...

2004 - Gale Group | Sunday Times HA GDA

Revisão Acesso aberto Brasil Produção Nacional Revisado por pares

Alicia S. Ombredane, Vitória R. P. Silva, Laise Rodrigues de Andrade, Willie Oliveira Pinheiro, Mayara Simonelly, Jaqueline Vaz de Oliveira, Andréia C. Pinheiro, Gabriel F. Gonçalves, Gisela J. Felice, Mônica Pereira Garcia, Patrícia Mazureki Campos, Glécia Virgolino da Silva Luz, Graziella Anselmo Joanitti,

Breast cancer is one of the most prevalent types of malignant tumors in the world, resulting in a high incidence of death. The development of new molecules and technologies aiming to apply more effective and safer therapy strategies has been intensively explored to overcome this situation. The association of nanoparticles with known antitumor compounds (including plant-derived molecules such as curcumin) has been considered an effective approach to enhance tumor growth suppression and reduce adverse ...

Tópico(s): Retinoids in leukemia and cellular processes

2021 - Frontiers Media | Frontiers in Oncology

Jornais Acesso aberto

Andrew Robson, Simon Barnes Chief Sports Writer, Paul Connelly, Jon Ashworth, Cath Urquhart, Stella Shamoon, Jeremy Skidmore, Caroline Morrow-Brown, Robert Cole, Portia Colwell, Matthew Syed, Catherine Riley, Roderick Straznge, David Brown, Blundell's Patch, Patricia Davies, James Moore, Richard Corrigan, Sarah Potter, Maggie Alderson, Paddy Whiting, Simon Barnes, Robert Vincent, Matthew Crockatt, George Pendle, John Phillips and Dragan Petrovic, Paul Hoggart, Mark Souster, Fanny Biske, Richard Hobson, Sam Lister, Barnaby Thompson and John Goodbody, Ivo Tennant, Philip Shirley, Anthony Browne and Jill Sherman, Brian Hogbin, Philip Howard, Ian Cobain, Carol Midgley, William Bond, Willie Peterie, James Bone, Melissa Katsoulis, Nic Hopkins, John Russel Taylor, Anne Gatti, Helen Studd and David Charter, Fonatban Meades, Elizabeth Judge, Lynne Truss, Jeremy Whittle, Geoff Brown, Clare Stewart, Giles Coren, Chris Hulme, David Robertson and Richard Miles, Caroline Hendrie, Antonia Senior, Anne Fisher, Kelvin Eason, Mark Griffiths, Pat Gibson, Valerie Elliott Countryside Editor, David McVay, Ruth Gledhill, Religion Correspondent, Robert Plant, Hilary Rose, Vinny Lee, Donald Hutera, Katie Perry, Steve Keenan, Stewart Tendler Crime Correspondent, Katherine Swift, Debra Craine, Shirley English, Rory Watson, Adam Sage and Rory Watson, Bobby Robson, Joe Morgan, Jill Dupleix, Geoffrey Simpson, Dalya Alberge Arts Correspondent, Michael Mulvihill, Richard Ford Home Correspondent, Philip Bathard-Smith, Hannah Robson, Robin Young, Stephen Farrell, Peter Millar, Rodney Milnes, Andy Stephens, Candida Crewe, Rowland Whitehead, Adrian Chiles, Roland Watson, Brian J. Picken, David Hands, Mark Giles, Ron Lewis, Helen Rumbelow, Matt Dickinson Chief Football Correspondent, Bill Linton, David Charter, Tim Teeman, Mark Court, Anthea Lawson, James Urquhart, Angela Jameson, Kate Muir, Katty Kay and Roland Watson, Bernard Crick, Nick Tyler, Paula Hawkins, Vanora Bennett, Nigel Williamson, Nicole Swengley, Marth Waller, Mark Atherton, Neil Harman, Rick Broadbent, Stephen Burgen, Tom Baldwin, Mark Henderson Science Correspondent, Lee Karen Stow, Nigel Bowden, K. A. Yeomans, Guyon Espiner, Geoffrey Wansell, Geoffrey Dean, Rob Wright, Rachael Jolley, Celia M. Middleton, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, N. Osborn, Boris Becker, Raymond Keene, Adam Sage, Ian Edgar, Lewis Smith, Ellis Cashmore, Lucy Pinney, Robert Oulds Director, Jan MacQuitty, Rory Watson and David Charter, Joseph Stiglitz, Dear Jill, James Allcock, Colin Buchanan, Robin Ash, Greg Hurst Parliamentary Correspondent, Xan Rice, Neville Scott, Ian Redmond, Russell Hotten, Richard Owen, Anthony Browne Environment Editor, David Charter and Rory Watson, Christopher Martin-Jenkins Chief Cricket Correspondent, Helen Nugent, David Blundell, Roger Boyes, Oliver August, Nick Hasell, Mark Turner, David Hands Rugby Correspondent, Tony Cascarino, Owen Slot Chief Sports Reporter, Tom Dart, James Collard, Lisa Verico, John Allison, Steve Jelbert, Joe Morgan and Helen Nugent, Nick Szczepanik, Anne Ashworth, Dominic Kennedy, Miss Abigail's, Philip Webster Political Editor, Katty Kay, James Pringle, Sophie Ratcliffe, Ian Johns, Mel Webb, Mike Berry, Barnaby Thompson, B. K. Avis, Kevin McCarra, Matthew Parris, Nick McDonell's, Sarah Turner and Caroline Hendrie, Chris McGrath, George Caulkin, Alan Franks, Russell Jenkins, Clarissa Hyman, Keith Blackmore, Sheila Keating, Iain Finlayson, Rose Aidin, David Elleray, Ben MacIntyre, Lea Paterson Economics Editor, Fiona Hook, Andrew Dakyns, Richard Beeston, Ben Bevington and Mica Schneider, David Matin, Alison Gibson, Gabriella Starkey, Richard Miles, John Naish, Simon Jenkins, Annabelle Thorpe, MacQuitty's, Martin Waller, Mark Henderson, Michael Horsnell, Kenneth MacNab, Chris Ayres, Danny Baker, Lottie Moggach, James Jackson, Benedict Nightingale, Angus Batey, Roger Peers, Jill Crawshaw, Hugh Thompson, David Powell, Frances Gibb, Tom Chesshyre, Bill Edgar, Alyson Rudd, Paul Connolly, Martin Lee's, Natalie Clein, Robert Whymant, Alan Lee Racing Correspondent, Richard Knight, Jenny Davey, Tom Baldwin and Alice Miles, David Robertson, Joahna Hunter, Colin McQuillan, Christina Kening, Christopher Irvine, Gary Rathbone,

... stays on On the streets Fans vent anger Oliveira's vow Engel sacked Perugia pounce Handle with ...

2002 - Gale Group | TDA

Artigo Brasil Produção Nacional Revisado por pares

Priscila Dinah Lima Oliveira, Kataryne Árabe Rimá de Oliveira, Willie Anderson dos Santos Vieira, Marcos Paz Saraiva Câmara, Evandro Leite de Souza,

This study assessed the efficacy of chitosan (Chi) and Cymbopogon citratus (D.C. ex Nees) Stapf. essential oil (CCEO) combinations to control the mycelial growth of five pathogenic Colletotrichum species (C. asianum, C. siamense, C. fructicola, C. tropicale and C. karstii) in vitro, as well as the anthracnose development in guava (Psidium guajava L.) cv. Paluma, mango (Mangifera indica L.) cv. Tommy Atkins and papaya (Carica papaya L.) cv. Papaya artificially inoculated with these species. Combinations ...

Tópico(s): Plant Pathogens and Fungal Diseases

2017 - Elsevier BV | International Journal of Food Microbiology

Revisão Acesso aberto Brasil Produção Nacional Revisado por pares

Fernanda Silvestre, Carolina Alves dos Santos, Vitória Silva, Alicia S. Ombredane, Willie Oliveira Pinheiro, Laise Rodrigues de Andrade, Mónica Ramírez García, Thyago José Arruda Pacheco, Graziella Anselmo Joanitti, Glécia Virgolino da Silva Luz, Marcella Lemos Brettas Carneiro,

Curcumin is a polyphenolic compound, derived from Curcuma longa, and it has several pharmacological effects such as antioxidant, anti-inflammatory, and antitumor. Although it is a pleiotropic molecule, curcumin’s free form, which is lipophilic, has low bioavailability and is rapidly metabolized, limiting its clinical use. With the advances in techniques for loading curcumin into nanostructures, it is possible to improve its bioavailability and extend its applications. In this review, we gather evidence ...

Tópico(s): Natural product bioactivities and synthesis

2023 - Multidisciplinary Digital Publishing Institute | Pharmaceuticals

Revisão Acesso aberto Brasil Produção Nacional Revisado por pares

Maria Eduarda Pérez‐deOliveira, Willie F. P. van Heerden, Ana Carolina Fragoso Motta, Carla Isabelly Rodrigues‐Fernandes, Mário José Romanãch, Michelle Agostini, Luiz Alcino Gueiros, Pablo Agustín Vargas, Márcio Ajudarte Lopes, Ana Carolina Prado Ribeiro, Thaís Bianca Brandão, Oslei Paes de Almeida, Syed Ali Khurram, Alan Roger Santos‐Silva,

Good communication between clinicians and pathologists is a vital element in the diagnostic process, and poor communication can adversely affect patient care. There is a lack of research about communication in diagnostic oral and maxillofacial pathology. This narrative review explores different aspects of the quality of communication between clinicians and oral pathologists, with a focus on the diagnosis of oral and maxillofacial diseases. An electronic search was carried out in MEDLINE through ...

Tópico(s): Head and Neck Cancer Studies

2022 - Brazilian Society of Dental Research | Brazilian Oral Research

Artigo Brasil Produção Nacional Revisado por pares

Giovanna Alencar Lundgren, Selma dos Passos Braga, Thatyane Mariano Rodrigues de Albuquerque, Katarine Árabe Rimá de Oliveira, Josean Fechine Tavares, Willie Anderson dos Santos Vieira, Marcos Paz Saraiva Câmara, Evandro Leite de Souza,

This study evaluated the inhibitory effects on mycelial growth and damage on membrane integrity and enzymatic activity caused by Conyza bonariensis essential oil (CBEO) on distinct pathogenic Colletotrichum musae isolates, as well as the preventive and curative effects of coatings with gum Arabic (GA) and CBEO to reduce anthracnose development in banana during room temperature storage. The effects of GA-CBEO coatings on some physicochemical parameters of banana were investigated during room temperature ...

Tópico(s): Plant Pathogens and Fungal Diseases

2021 - Oxford University Press | Journal of Applied Microbiology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Willie Anderson dos Santos Vieira, Sami Jorge Michereff, A. C. B. de Oliveira, Armínio Santos, Marcos Paz Saraiva Câmara,

In January 2011, leaves of several daylily (Hemerocallis flava L.) plants in nurseries in Vitória da Conquista, northeastern Brazil, showed typical anthracnose symptoms. Reddish brown lesions with a yellow halo were first observed at the tip leaves. As the disease progressed, the lesions rapidly expanded down the leaves, resulting in severe blight. Small pieces up to 5 mm in diameter were removed from the lesion margins, surface sterilized for 1 min in 1.5% NaOCl, washed twice with sterile distilled ...

Tópico(s): Yeasts and Rust Fungi Studies

2014 - American Phytopathological Society | Plant Disease

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Willie Oliveira Pinheiro, Maria Luiza Fascineli, Gabriel Ribeiro Farias, Frederíco Hillesheim Horst, Laise Rodrigues de Andrade, Luís Henrique Corrêa, Kelly Grace Magalhães, Marcelo Henrique Sousa, Marcos Célio de Almeida, Ricardo Bentes Azevedo, Z.G.M. Lacava,

Magnetic nanoparticles (MNPs) have been successfully tested for several purposes in medical applications. However, knowledge concerning the effects of nanostructures on elderly organisms is remarkably scarce.To fill part of this gap, this work aimed to investigate biocompatibility and bio-distribution aspects of magnetic nanoparticles coated with citrate (NpCit) in both elderly and young healthy mice.NpCit (2.4 mg iron) was administered intraperitoneally, and its toxicity was evaluated for 28 days ...

Tópico(s): Nanoparticle-Based Drug Delivery

2019 - Dove Medical Press | International Journal of Nanomedicine

Artigo Brasil Produção Nacional Revisado por pares

Alicia S. Ombredane, Laise Rodrigues de Andrade, Raphael Severino Bonadio, Willie Oliveira Pinheiro, Ricardo Bentes Azevedo, Graziella Anselmo Joanitti,

Combined 5-fluorouracil (5-FU) and melittin (MEL) is believed to enhance cytotoxic effects on skin squamous cell carcinoma (SCC). However, the rationale underlying cytotoxicity is fundamentally important for a proper design of combination chemotherapy, and to provide translational insights for future therapeutics in the dermatology field. The aim was to elucidate the effects of 5-FU/MEL combination on the viability, proliferation and key structures of human squamous cell carcinoma (A431). Morphology, ...

Tópico(s): Insect and Pesticide Research

2021 - Wiley | Experimental Dermatology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Marcela Guimarães Landim, Marcella Lemos Brettas Carneiro, Graziella Anselmo Joanitti, Carla Tatiana Mota Anflor, David Dobkowski Marinho, José Filipe Bacalhau Rodrigues, Wladymyr Jéfferson Bacalhau de Sousa, Daniel de Oliveira Fernandes, Beatriz Ferreira Souza, Alicia S. Ombredane, Jéssica Catarine Frutuoso do Nascimento, Gisela de Jesus Felice, Aline Midori Adati Kubota, Juliana Simas Coutinho Barbosa, John Hideki Ohno, Solomon Kweku Sagoe Amoah, Lindomar Pena, Glécia Virgolino da Silva Luz, Laise Rodrigues de Andrade, Willie Oliveira Pinheiro, Bergmann Morais Ribeiro, Fábio Rocha Formiga, Marcus Vinícius Lia Fook, Mário Fabrício Fleury Rosa, Henry Maia Peixoto, Rodrigo Luiz Carregaro, Suélia de Siqueira Rodrigues Fleury Rosa,

Abstract Background It is known that some sectors of hospitals have high bacteria and virus loads that can remain as aerosols in the air and represent a significant health threat for patients and mainly professionals that work in the place daily. Therefore, the need for a respirator able to improve the filtration barrier of N95 masks and even inactivating airborne virus and bacteria becomes apparent. Such a fact motivated the creation of a new N95 respirator which employs chitosan nanoparticles ...

Tópico(s): Respiratory viral infections research

2023 - | Discover Nano

Artigo Brasil Produção Nacional Revisado por pares

Ana Luiza Oliveira Corrêa Roza, Román Carlos, Willie F. P. van Heerden, Bruno Augusto Benevenuto de Andrade, Adalberto Mosqueda‐Taylor, Alan Roger Santos‐Silva, Márcio Ajudarte Lopes, Oslei Paes de Almeida, Mário José Romanãch, Pablo Agustín Vargas,

Objective The aim of this study was to report the clinicopathologic features of 105 new cases of adenomatoid odontogenic tumor (AOT) from Brazil, Guatemala, Mexico, and South Africa. Study Design Clinical and radiographic data were collected from records of 5 oral pathology laboratories, and all cases were microscopically reviewed. Results This series of cases included 36 (34.2%) from South Africa; 33 (31.4%) from Brazil; 23 (21.9%) from Mexico; and 13 (12.3%) from Guatemala. Seventy-two patients (68. ...

Tópico(s): Oral and gingival health research

2020 - Elsevier BV | Oral Surgery Oral Medicine Oral Pathology and Oral Radiology

Artigo Brasil Produção Nacional Revisado por pares

Laise Rodrigues de Andrade, Antônio Cláudio Tedesco, Fernando Lucas Primo, Gabriel Ribeiro Farias, Da Silva, João Paulo Figueiró Longo, Marcos Célio de Almeida, Paulo EN de Souza, Ricardo Bentes Azevedo, Willie Oliveira Pinheiro, Zulmira GM Lacava,

Aim: Nano-5-aminolevulic acid (NanoALA)-mediated photodynamic therapy (PDT), an oil-in-water polymeric nanoemulsion of ALA, was evaluated in a murine model of breast cancer. Materials & methods: Analysis of ALA-derived protoporphyrin IX production and acute toxicity test, biocompatibility and treatment efficacy, and long-term effect of NanoALA-PDT on tumor progression were performed. Results: The nanoformulation favored the prodrug uptake by tumor cells in a shorter time (1.5 h). As a result, the adverse ...

Tópico(s): Porphyrin and Phthalocyanine Chemistry

2020 - Future Medicine | Nanomedicine

Revisão Brasil Produção Nacional Revisado por pares

Allan Vinícius Martins‐de‐Barros, Caio César Gonçalves Silva, Kalyne Kelly Negromonte Gonçalves, Renata de Albuquerque Cavalcanti Almeida, Emanuel Dias de Oliveira e Silva, Fábio Andrey da Costa Araújo, Liam Robinson, Willie F. P. van Heerden, Marianne de Vasconcelos Carvalho,

Abstract Objective The objective of this systematic review with meta‐analysis was to critically evaluate the available data on the association of the BRAF V600E mutation and recurrence rate of ameloblastomas. Materials and Methods This systematic review was registered in Prospero (CRD42020183645) and performed based on the PRISMA statement. A comprehensive search in PubMed, Web of Science, Scopus and Cochrane Library databases was performed in order to answer the question “Does BRAF V600E mutation ...

Tópico(s): Hedgehog Signaling Pathway Studies

2023 - Wiley | Journal of Oral Pathology and Medicine

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Anderson José Paulo, Maria Carolina de Albuquerque Wanderley, Rafael José Vilela de Oliveira, Willie Anderson dos Santos Vieira, Luiz Carlos Alves, Daniela de Araújo Viana Marques, Attílio Converti, Ana Lúcia Figueiredo Porto,

β-Galactosidase production, partial purification and characterization by a new fungal were investigated. Partial purification was performed by aqueous two-phase system (ATPS) using polyethylene glycol (PEG) molar mass, PEG concentration, citrate concentration and pH as the independent variables. Purification factor (PF), partition coefficient (K) and yield (Y) were the responses. After identification by rDNA sequencing and classification as Cladosporium tenuissimum URM 7803, this isolate achieved a maximum ...

Tópico(s): Microbial Metabolic Engineering and Bioproduction

2020 - Taylor & Francis | Preparative Biochemistry & Biotechnology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Andréia C. Pinheiro, Alicia S. Ombredane, Willie Oliveira Pinheiro, Laise Rodrigues de Andrade, Vitória R. P. Silva, Gisela J. Felice, Débora S. Alves, Aryanne F. Albernaz, Ariane Pandolfo Silveira, Milena C. F. Lima, Valdir Florêncio da Veiga, Thamis F. S. Gomes, Emanuel Adelino Medeiros Damasceno, Fabiane H. Veiga‐Souza, Paulo Eduardo Narcizo de Souza, Sônia Nair Báo, Eliza Carla Barroso Duarte, Marcella Lemos Brettas Carneiro, Ricardo Bentes Azevedo, Mani Indiana Funez, Graziella Anselmo Joanitti,

Pequi oil (Caryocar brasiliense) contains bioactive compounds capable of modulating the inflammatory process; however, its hydrophobic characteristic limits its therapeutic use. The encapsulation of pequi oil in nanoemulsions can improve its biodistribution and promote its immunomodulatory effects. Thus, the objective of the present study was to formulate pequi oil-based nanoemulsions (PeNE) to evaluate their biocompatibility, anti-inflammatory, and antinociceptive effects in in vitro (macrophages— ...

Tópico(s): Dermatology and Skin Diseases

2022 - Multidisciplinary Digital Publishing Institute | Nanomaterials

Artigo

Willie Oliveira Pinheiro, Maria Luiza Fascineli, Khellida Loiane Vieira Ramos, Laise Rodrigues de Andrade, Gabriel Ribeiro Farias, Maria de Sousa Brito Neta, Luís Henrique Corrêa, Eliza Carla Barroso Duarte, Emanuel Adelino Medeiros Damasceno, Kelly Grace Magalhães, Da Silva, Ricardo Bentes Azevedo, Marcelo Henrique Sousa, Z.G.M. Lacava,

Nanobiotechnology strategies for cancer treatments are currently being tested with increasing interest, except in elderly groups. It is well established that breast cancer incidence increases with age and that traditional therapies usually generate severe adverse effects, especially for elderly groups. To investigate if the benefits of nanotechnology could be extended to treating cancer in this group, citrate-coated maghemite nanoparticles (NpCit) were used for magnetohyperthermia (MHT) in combination ...

Tópico(s): Microfluidic and Bio-sensing Technologies

2020 - American Scientific Publishers | Journal of Biomedical Nanotechnology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ibrahim Alsanie, Shahad Rajab, Hannah Cottom, Oluyori Kutulola Adegun, Reshma Agarwal, Amrita Jay, Laura Graham, Jacqueline A. James, A.W. Barrett, Willie F. P. van Heerden, Mariano de Vito, Alessandra Canesso, Akinyele Olumuyiwa Adisa, Abdulwarith Akinshipo, O. F. Ajayi, Mark Chukwuemeka Nwoga, Chukwubuzor Udokwu Okwuosa, Olufemi Gbenga Omitola, Efetobo Victor Orikpete, Merva Soluk Tekkeşin, Ibrahim O. Bello, Ahmed Qannam, Wilfredo Gonzalez, Maria Eduarda Pérez‐deOliveira, Alan Roger Santos‐Silva, Pablo Agustín Vargas, Eu-Wing Toh, Syed Ali Khurram,

Abstract Background Salivary gland tumours (SGT) are a relatively rare group of neoplasms with a wide range of histopathological appearance and clinical features. To date, most of the epidemiological studies on salivary gland tumours are limited for a variety of reason including being out of date, extrapolated from either a single centre or country studies, or investigating either major or minor glands only. Methods This study aimed to mitigate these shortcomings by analysing epidemiological data ...

Tópico(s): Oral and Maxillofacial Pathology

2022 - Springer Science+Business Media | Head and Neck Pathology

Artigo Acesso aberto Brasil Produção Nacional

Willie Oliveira Pinheiro, Laise Rodrigues de Andrade, Marcelo Henrique Sousa, Mayara Simonelly Costa do Santos, Gabriel Ribeiro Farias, Graziella Anselmo Joanitti,

Breast cancer is a group of malignancies most common among women. In 2018, approximately 2.1 million women were diagnosed, with 626,679 deaths. The traditional classification of these diseases is based on the extent of illness (in situ or invasive), the affected tissue (epithelial tissue for instance), and the site of occurrence (duct or lobe). The invasive ductal carcinoma is the most common type. The classification based on molecular characteristics divides breast cancer into at least five groups: ...

Tópico(s): Metabolomics and Mass Spectrometry Studies

2021 - Brazilian Society of Mastology | Mastology

Artigo Brasil Produção Nacional Revisado por pares

William Rosa de Oliveira Soares, Willie Anderson dos Santos Vieira, Ailton Reis, Robert G. Miller, Maria do Desterro Mendes dos Santos, Érica de Castro Costa, Marcos Paz Saraiva Câmara, Adalberto C. Café‐Filho,

Abstract Anthracnose, caused by several Colletotrichum species, is a major restricting factor for guava production, but no comprehensive study of the causal agent has been conducted from the plant host centre of diversity. This work characterizes isolates from guava, mainly from the fruit, but also leaves and flowers, representing most Brazilian physiographies according to the partial sequences of the rDNA‐ITS, ApMAT , TUB2 , HIS3 and GAPDH gene regions. In addition, the pathogenicity and aggressiveness ...

Tópico(s): Psidium guajava Extracts and Applications

2024 - Wiley | Plant Pathology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Elis Regina Lima Siqueira, Willie Oliveira Pinheiro, V. R. R. Aquino, Breno Cunha Pinto Coelho, Andris F. Bakuzis, Ricardo Bentes Azevedo, Marcelo Henrique Sousa, P.C. Morais,

This study investigated the fabrication of spherical gold shelled maghemite nanoparticles for use in magnetic hyperthermia (MHT) assays. A maghemite core (14 ± 3 nm) was used to fabricate two samples with different gold thicknesses, which presented gold (g)/maghemite (m) content ratios of 0.0376 and 0.0752. The samples were tested in MHT assays (temperature versus time) with varying frequencies (100-650 kHz) and field amplitudes (9-25 mT). The asymptotic temperatures (T∞) of the aqueous suspensions (40 mg ...

Tópico(s): Gold and Silver Nanoparticles Synthesis and Applications

2022 - Multidisciplinary Digital Publishing Institute | Nanomaterials

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maria Eduarda Pérez‐deOliveira, Thayná Melo de Lima Morais, Márcio Ajudarte Lopes, Oslei Paes de Almeida, Willie F. P. van Heerden, Pablo Agustín Vargas,

ABSTRACT: Ossifying fibromyxoid tumor (OFMT) is a rare mesenchymal soft tissue benign neoplasm with an uncertain line of differentiation, which arises most frequently in extremities. The head and neck region involvement is uncommon, with only ten intraoral cases published in the English-language literature. One additional case of OFMT is reported here, including a literature review of intraoral reported cases. A 45-year-old female patient presented a painless nodule involving the buccal mucosa of ...

Tópico(s): Oral and Maxillofacial Pathology

2020 - UNIVERSIDADE DE SÃO PAULO | Autopsy and Case Reports

Revisão Brasil Produção Nacional Revisado por pares

Maria Eduarda Pérez‐deOliveira, Liam Robinson, José Narciso Rosa Assunção Júnior, Aline Corrêa Abrahão, Mário José Romanãch, Paulo Victor Mendes Penafort, Luan César Silva, Alan Roger Santos‐Silva, Márcio Ajudarte Lopes, Willie F. P. van Heerden, Pablo Agustín Vargas,

This study reports 9 additional tongue hamartomas in children paired with a literature review.A retrospective analysis was performed from 3 Oral Pathology laboratories.Additionally, a literature review was conducted through 5 electronic databases and gray literature.A total of 9 cases were identified in the retrospective analysis.Females outnumbered males with a ratio of 1.25:1.The age of presentation ranged from 2 weeks to 7 years.The posterior dorsum tongue was the most affected subsite (n = 4).One ...

Tópico(s): Oral and Maxillofacial Pathology

2022 - Elsevier BV | Oral Surgery Oral Medicine Oral Pathology and Oral Radiology

Artigo Revisado por pares

Maria Eduarda Pérez‐deOliveira, Liam Robinson, Willie F. P. van Heerden, José Narciso Rosa Assunção, Pablo Agustín Vargas,

A hamartoma is the proliferation of normal tissues that are considered endogenous to the site of occurrence. Hamartomas are rarely seen in the oral cavity. The aim of this study is to report clinicopathologic features of 8 additional tongue hamartoma cases in pediatric patients. Female patients outnumbered male patients by 1:6, and the age of patients ranged from 2 weeks to 4 years old. One case was associated with oral-facial-digital syndrome and another one with the presence of cleft palate and ...

Tópico(s): Hedgehog Signaling Pathway Studies

2022 - Elsevier BV | Oral Surgery Oral Medicine Oral Pathology and Oral Radiology

Artigo Revisado por pares

Willie G. Harris,

Acid leaching for different types of mixed spent Li-ion mobile batteries is carried out after alkali decomposition using NH4OH followed by H2SO4 + H2O2 leaching. In the alkali decomposition step, the effects of reaction time, NH4OH concentration, liquid/solid mass ratio and reaction temperature on the decomposition process are investigated to remove Al, Cu, Mn, Ni, Co, and Li. After alkaline treatment, the alkali paste is treated to leach the remaining metals using H2SO4 + H2O2. The significant effects ...

Tópico(s): Advanced Battery Technologies Research

1987 - Elsevier BV | International Journal of Fatigue

Artigo Revisado por pares

Ana Luiza Oliveira Corrêa Roza, Román Carlos, Willie F. P. van Heerden, Bruno Augusto Benevenuto de Andrade, Alan Roger Santos‐Silva, Mário José Romanãch, Pablo Agustín Vargas,

The aim of this study was to report the clinicopathologic and radiographic features of 80 cases of adenomatoid odontogenic tumor (AOT) from Guatemala, Brazil, and South Africa. Clinical data were collected from records of 4 oral pathology laboratories, and all cases were microscopically reviewed considering the current World Health Organization Classification. The series included 12 cases from Guatemala, 32 cases from Brazil, and 36 cases from South Africa. Fifty-four patients (68%) were female, and ...

Tópico(s): Salivary Gland Tumors Diagnosis and Treatment

2020 - Elsevier BV | Oral Surgery Oral Medicine Oral Pathology and Oral Radiology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maria Luiza Fascineli, Paolin Rocio Cáceres‐Vélez, Willie Oliveira Pinheiro, Sacha Braun Chaves, Marcelo Henrique Sousa, Wilson Sacchi Peternella, Frederíco Hillesheim Horst, Michele de Castro Fernandes, Wania Guimarães, Ricardo Bentes Azevedo, César Koppe Grisólia,

Iron oxide nanoparticles (FeO-NPs) are widely used in scientific and technological fields. Environmental concerns have been raised about residual FeO-NPs levels as their toxicity and bioaccumulative potential are not well understood. Oreochromis niloticus were exposed to nanoparticles of γ-Fe2O3 and Fe3O4. Micro-CT 3D image and grayscale graphic assessments revealed the accumulation of radiopaque material in the digestive tract of fish exposed to FeO-NPs. Histological analysis showed the presence ...

Tópico(s): Microplastics and Plastic Pollution

2024 - Brazilian Society of Genetics | Genetics and Molecular Biology