Lei Yang, Massimiliano Ferrucci, Raya Mertens, Wim Dewulf, Chunze Yan, Yusheng Shi, Shoufeng Yang,
Triply periodic minimal surfaces (TPMSs) have attracted increasing attention for their high manufacturability, biocompatibility, and mechanical properties. In this work, graded Gyroid cellular structures (GCSs) with varying gradient directions were mathematically designed and manufactured via selective laser melting (SLM). The effect of gradients on manufacturing fidelity, i.e. degree of conformity between the manufactured part and engineering design, of these structures was investigated using X-ray ...
Tópico(s): 3D Shape Modeling and Analysis
2019 - Elsevier BV | Journal of Materials Processing Technology
H Hendrix, T. Lindhout, K. Mertens, Wim Engels, H.C. Hemker,
The activation of human prothrombin by the bacterial protein staphylocoagulase proceeds via the formation of a very stable equimolar complex.Unmasking of the active center in the prothrombin moiety of the complex is not caused by limited proteolysis.The kinetics of activation of human prothrombin by staphylocoagulase has been studied.The second order rate constant at pH 7.5, 37 "C, is 3.3 X lo6 M" s-'.This reaction rate is close to reported diffusion-controlled rates of protein-protein interaction. ...
Tópico(s): Hemoglobin structure and function
1983 - Elsevier BV | Journal of Biological Chemistry
Armand V. Peeters, Sigri Beckers, Ilse Mertens, Wim Van Hul, Luc Van Gaal,
Tópico(s): Pancreatic function and diabetes
2007 - Springer Science+Business Media | Endocrine
Xenia Vamvakoussi, Konstantinos P. Christou, Lieve Mertens, Wim Van Dooren,
Tópico(s): Statistics Education and Methodologies
2011 - Elsevier BV | Learning and Instruction
Jelle Mertens, Wim Bastiaens, B. Dehandschutter,
Excavation works were carried out in Boom Clay to extend the underground research facility in Mol (Belgium) located at a depth of 223 m below the surface. The attempt to characterise the extent of the Excavation Damaged Zone, or EDZ, around the second shaft, using seismic measurements and cored borings, was successful, as proven by observations during further excavation works in the investigated area. No evidence for the occurrence of natural discontinuities was found. Using an industrial technique, ...
Tópico(s): Geotechnical and construction materials studies
2004 - Elsevier BV | Applied Clay Science
Wouter Houthoofd, Maxime Willems, Sandra Vangestel, Clarinda Mertens, Wim Bert, Gaëtan Borgonie,
SUMMARY The morphogenesis of a gut from the endoderm has been well studied among the animal kingdom and is also well described in the nematode Caenorhabditis elegans . But are there other ways to build a nematode intestine? Sulston et al. (1983) described a different intestinal cell lineage in the species Panagrellus redivivus and Turbatrix aceti that includes two programmed cell deaths. However, no details are known about the three‐dimensional (3D) configuration and the role of the cell deaths. Here, ...
Tópico(s): Agriculture Sustainability and Environmental Impact
2006 - Wiley | Evolution & Development
D. Moira Glerum, Dirk Claeys, Wim Mertens, Angelo Azzi,
The tricarboxylate carrier from rat liver mitochondria has been purified and reconstituted into phospholipid vesicles. Its activity has been characterized by both a radioactive citrate uptake assay and a coupled enzymatic assay. A Km of 40 microM and a Vmax of 1.56 mumol x min-1 x mg-1 have been determined for the carrier. Cholesterol levels of between 5-10% of total lipid content are shown to cause a decrease in carrier activity.
Tópico(s): Adipose Tissue and Metabolism
1990 - Wiley | European Journal of Biochemistry
Karl Kroeger, Wim Mertens, J. Hautekiet, Michael Nyman,
Tópico(s): Musicology and Musical Analysis
1988 - University of Illinois Press | American Music
Marian Gerard, Mohssine El Kahloun, Wim Mertens, Bart Verhagen, Patrick Meire,
Tópico(s): Plant Water Relations and Carbon Dynamics
2007 - Springer Science+Business Media | Plant Ecology
Angelo Azzi, M. Glerum, Richard L. Koller, Wim Mertens, Stefan Spycher,
Tópico(s): Enzyme Structure and Function
1993 - Springer Science+Business Media | Journal of Bioenergetics and Biomembranes
... been criticized for its inaccurate and misleading connotations. Wim Mertens, for example, asks whether extreme reduction of the ...
Tópico(s): Art, Politics, and Modernism
1993 - Perspectives of New Music | Perspectives of New Music
Liesbeth De Keukelaere, Robrecht Moelans, Els Knaeps, Sindy Sterckx, I. Reusen, Dominique De Munck, Stefan Simis, Adriana Maria Constantinescu, Albert Scrieciu, Georgios Katsouras, Wim Mertens, Peter Hunter, Evangelos Spyrakos, Andrew N. Tyler,
Using airborne drones to monitor water quality in inland, transitional or coastal surface waters is an emerging research field. Airborne drones can fly under clouds at preferred times, capturing data at cm resolution, filling a significant gap between existing in situ, airborne and satellite remote sensing capabilities. Suitable drones and lightweight cameras are readily available on the market, whereas deriving water quality products from the captured image is not straightforward; vignetting effects, ...
Tópico(s): Marine and coastal ecosystems
2023 - Multidisciplinary Digital Publishing Institute | Remote Sensing
Aditi Thanki, Louca Goossens, Raya Mertens, Gabriel Probst, Wim Dewulf, Ann Witvrouw, Shoufeng Yang,
The occurrence of keyhole porosity in selective laser melting (SLM) has so far not been quantified systematically using X-ray computed tomography (X-CT). In this study, keyhole porosity in selective laser molten Ti-6Al-4V grade 23 parts was analyzed using post-process characterizations. Single tracks were produced with optimum, high volumetric energy density and low volumetric energy density parameters on the top of SLM substrate. High volumetric energy density was achieved by either (i) high laser ...
Tópico(s): Welding Techniques and Residual Stresses
2019 - | EasyChair preprint
Louke Delrue, Peter Blanckaert, Dokus Mertens, Ercan Cesmeli, Wim Ceelen, Wouter Duyck,
Computed tomography (CT) perfusion studies can provide valuable information regarding tumor vascularization. We report on a study assessing CT perfusion characteristics in the normal pancreas and in patients with pancreatic adenocarcinoma.Twenty healthy subjects and 20 patients with histologically confirmed pancreatic adenocarcinoma were included in the study after written informed consent and approval by our institutional review board. All subjects underwent perfusion CT imaging of the pancreas ...
Tópico(s): Pancreatic and Hepatic Oncology Research
2011 - Lippincott Williams & Wilkins | Journal of Computer Assisted Tomography
Erik Storkebaum, Diether Lambrechts, Mieke Dewerchin, Paz Moreno-Murciano, Saskia Appelmans, Hideyasu Oh, Philip Van Damme, Bart P. F. Rutten, W.Y. Man, Maria De Mol, Sabine Wyns, David Manka, Kristel Vermeulen, Ludo Van Den Bosch, Nico Mertens, Christoph Schmitz, Wim Robberecht, Edward M. Conway, D Collen, Lieve Moons, Peter Carmeliet,
Neurotrophin treatment has so far failed to prolong the survival of individuals affected with amyotrophic lateral sclerosis (ALS), an incurable motoneuron degenerative disorder. Here we show that intracerebroventricular (i.c.v.) delivery of recombinant vascular endothelial growth factor (Vegf) in a SOD1(G93A) rat model of ALS delays onset of paralysis by 17 d, improves motor performance and prolongs survival by 22 d, representing the largest effects in animal models of ALS achieved by protein delivery. ...
Tópico(s): Neurogenetic and Muscular Disorders Research
2004 - Nature Portfolio | Nature Neuroscience
Liesbet Jacobs, Jan Maes, Kewan Mertens, John Sekajugo, Wim Thiery, Nicole Van Lipzig, Jean Poesen, Matthieu Kervyn, Olivier Dewitte,
Tópico(s): Flood Risk Assessment and Management
2016 - Springer Science+Business Media | Natural Hazards
Karel Kellens, Raya Mertens, Dimos Paraskevas, Wim Dewulf, Joost R. Duflou,
While additive manufacturing applications are progressing from rapid prototyping to the production of end-use products, the environmental impacts caused by these manufacturing processes and related material flows are still a rather open question. Therefore, this paper will provide an overview of available life cycle inventory data and compare the environmental impact caused by a series of additive manufacturing processes: selective laser melting, selective laser sintering, electron beam melting, ...
Tópico(s): Additive Manufacturing Materials and Processes
2017 - Elsevier BV | Procedia CIRP
Esmée C. de Baat, Elvira C van Dalen, Renée L. Mulder, Melissa M. Hudson, Matthew J. Ehrhardt, Frederike K. Engels, Elizabeth A. M. Feijen, Heynric B. Grotenhuis, Jan M. Leerink, Livia Kapusta, Gertjan J.L. Kaspers, Remy Merkx, Luc Mertens, Roderick Skinner, Wim J. E. Tissing, Florent de Vathaire, Paul C. Nathan, Leontien C.M. Kremer, Annelies M. C. Mavinkurve‐Groothuis, Saro H. Armenian,
Survivors of childhood cancer are at risk of anthracycline-induced cardiotoxicity, which might be prevented by dexrazoxane. However, concerns exist about the safety of dexrazoxane, and little guidance is available on its use in children. To facilitate global consensus, a working group within the International Late Effects of Childhood Cancer Guideline Harmonization Group reviewed the existing literature and used evidence-based methodology to develop a guideline for dexrazoxane administration in ...
Tópico(s): Cancer-related cognitive impairment studies
2022 - Elsevier BV | The Lancet Child & Adolescent Health
Tópico(s): Protein Hydrolysis and Bioactive Peptides
1988 - Springer Science+Business Media | Applied Microbiology and Biotechnology
Georgios Scheiner‐Bobis, Wim Mertens, Martin Willeke, W. Schöner,
The synthesis of 8-thiocyano-ATP (CNS8-ATP) is described. At 37 degrees C the ATP analogue inactivates Na,K-ATPase, hexokinase, and pyruvate kinase. In all three cases, inactivation can be prevented by the addition of ATP, thus indicating that CNS8-ATP is recognized within the ATP binding site of the above enzymes. Incubation of the inactivated enzymes with dithiothreitol restores the catalytic activities. Therefore, it is likely that in these enzymes a mixed disulfide (E-S-S8-ATP) is formed between ...
Tópico(s): Ion Transport and Channel Regulation
1992 - American Chemical Society | Biochemistry
Laura S. Mertens, Wim Meinhardt, Walther B. Rier, Ronald I. Nooter, Simon Horenblas,
<b><i>Purpose:</i></b> To report our experience with symptomatic extravasation of intravesical chemotherapy administered within 24 h after transurethral resection (TUR) over the past 10 years. <b><i>Methods:</i></b> We identified all consecutive patients who presented with symptomatic extravasation of intravesical chemotherapy following TUR between 2001 and 2011. We assessed the severity of the postoperative complications using the modified Clavien system. < ...
Tópico(s): Urological Disorders and Treatments
2012 - Karger Publishers | Urologia Internationalis
Armand V. Peeters, Sigri Beckers, An Verrijken, Ilse Mertens, Luc Van Gaal, Wim Van Hul,
Tópico(s): Ubiquitin and proteasome pathways
2009 - Springer Science+Business Media | Endocrine
Sigri Beckers, Armand V. Peeters, Doreen Zegers, Ilse Mertens, Luc Van Gaal, Wim Van Hul,
Brain-derived neurotrophic factor (BDNF) has been implied in the regulation of food intake. In the present study, we genotyped the Val66Met polymorphism in a Belgian cohort of 532 obese women and 197 healthy female controls and were, for the first time, able to show an association of the 66Met allele with obesity, at least in our female cohort.
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2008 - Elsevier BV | Molecular Genetics and Metabolism
Louke Delrue, Peter Blanckaert, Delphine Mertens, S. Van Meerbeeck, Wim Ceelen, Wouter Duyck,
Tópico(s): Advanced MRI Techniques and Applications
2011 - Springer Nature | Abdominal Radiology
Laura S. Mertens, Richard P. Meijer, Wim Meinhardt, Henk G. van der Poel, Axel Bex, J. Martijn Kerst, Michiel S. van der Heijden, Andries M. Bergman, Simon Horenblas, Bas W.G. van Rhijn,
To investigate the effect of neoadjuvant chemotherapy (NAC) on the incidence of lymph node (LN) metastases in clinically node-negative (cN0) patients with carcinoma invading the bladder muscle (MIBC).Between 1990 and 2012, 828 consecutive patients underwent radical cystectomy (RC) with extended pelvic LN dissection (ePLND), of whom 441 had cT2-4N0M0 stage disease. A total of 83 patients received NAC then underwent RC and 358 patients underwent RC only. The ePLND template and the indication for NAC remained ...
Tópico(s): Urological Disorders and Treatments
2013 - Wiley | BJU International
Sigri Beckers, Doreen Zegers, Fenna de Freitas, Ilse Mertens, Luc F. Van Gaal, Wim Van Hul,
Recently, genome-wide association studies have discovered several single nucleotide polymorphisms (SNPs) involved in the etiology of complex obesity. A variant downstream from the melanocortin-4 receptor gene (MC4R), a gene known to be involved in monogenic obesity, was reported to be highly associated with BMI. In the present study, we performed a replication study with the previously reported SNP rs17782313. We also included 3 tagSNPs (rs8087522, rs11872992, and rs1943226) for the MC4R gene region ...
Tópico(s): Genetic Associations and Epidemiology
2011 - Elsevier BV | Molecular Genetics and Metabolism
Doreen Zegers, Sigri Beckers, Ilse Mertens, Luc F. Van Gaal, Wim Van Hul,
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2011 - Elsevier BV | Molecular Genetics and Metabolism
Birgit Mertens, Christian Blothe, Kim Windey, Wim De Windt, Willy Verstraete,
Tópico(s): Chemical Reactions and Isotopes
2006 - Elsevier BV | Chemosphere
May Y. Lind, Ingrid Mertens Zur Borg, Eric J. Hazebroek, Wim C.J. Hop, Ian P.J. Alwayn, Willem Weimar, Jan N.M. IJzermans,
Pneumoperitoneum, as used in laparoscopic donor nephrectomy (LDN), may result in negative effects on renal function in donor and recipient. This study compares long-term serum creatinine in donor and recipient after laparoscopic and open donor nephrectomy (ODN). A retrospective analysis of 120 LDN and 100 ODN donors and their recipients was performed. Serum creatinine of donor and recipient was recorded and analyzed. The follow-up period posttransplantation was 3 years. Serum creatinine in the recipients ...
Tópico(s): Organ Transplantation Techniques and Outcomes
2005 - Wolters Kluwer | Transplantation
Armand V. Peeters, Sigri Beckers, An Verrijken, Ilse Mertens, Peter Roevens, Pieter J. Peeters, Wim Van Hul, Luc F. Van Gaal,
Tópico(s): Biochemical effects in animals
2008 - Springer Science+Business Media | Human Genetics