
Lais Da Silva, Taynara Lourenço Da Silva, Alisson Henrique Antunes, Kênnia Rocha Rezende,
... Scholar, 12.Sjöberg Å. Lutz M. Tannergren C. Wingolf C. Borde A. Ungell A.L. Comprehensive study ... recommended.12.Sjöberg Å. Lutz M. Tannergren C. Wingolf C. Borde A. Ungell A.L. Comprehensive study ...
Tópico(s): Neuropeptides and Animal Physiology
2015 - Elsevier BV | Journal of Pharmaceutical Sciences
Amir Bein, Woojung Shin, Sasan Jalili‐Firoozinezhad, Min Hee Park, Alexandra Sontheimer-Phelps, Alessio Tovaglieri, Angeliki Chalkiadaki, Hyun Jung Kim, Donald E. Ingber,
... 104) Google ScholarNoYes100Sjöberg Å. Lutz M. Tannergren C. Wingolf C. Borde A. Ungell A.-L. Comprehensive study ...
Tópico(s): Cancer Cells and Metastasis
2018 - Elsevier BV | Cellular and Molecular Gastroenterology and Hepatology
Beatrice Kisser, Eva Mangelsen, Caroline Wingolf, Lars Ivo Partecke, Claus‐Dieter Heidecke, Christer Tannergren, Stefan Oswald, Markus Keiser,
Abstract The Ussing chamber is an old but still powerful technique originally designed to study the vectorial transport of ions through frog skin. This technique is also used to investigate the transport of chemical agents through the intestinal barrier as well as drug metabolism in enterocytes, both of which are key determinants for the bioavailability of orally administered drugs. More contemporary model systems, such as Caco‐2 cell monolayers or stably transfected cells, are more limited in their ...
Tópico(s): Pharmacogenetics and Drug Metabolism
2017 - Wiley | Current Protocols in Pharmacology
Åsa Sjöberg, Mareike Lutz, Christer Tannergren, Caroline Wingolf, Anders Borde, Anna‐Lena Ungell,
The purpose of this study was to evaluate the use of human intestinal tissue in Ussing chamber to predict oral and colonic drug absorption and intestinal metabolism. Data on viability, correlation between apparent permeability coefficients (Papp) and fraction absorbed (fa) after oral and colonic administration, regional permeability, active uptake and efflux of drugs as well as intestinal metabolism were compiled from experiments using 159 human donors. Permeability coefficients for up to 28 drugs ...
Tópico(s): Amino Acid Enzymes and Metabolism
2012 - Elsevier BV | European Journal of Pharmaceutical Sciences
Tópico(s): Ecology, Conservation, and Geographical Studies
2021 - Duncker & Humblot | Das Historisch-Politische Buch
Márton Kiss, Johan Nicolaï, JJMW van den Heuvel, Richard Mbasu, SM Botden, JB Koenderink, Frans G. M. Rüssel, AL Ungell, Saskia N. de Wildt,
... metabolism. Reference Sjöberg Å, Lutz M, Tannergren C, Wingolf C, Borde A, Ungell AL:Comprehensive study on ...
Tópico(s): Metabolism and Genetic Disorders
2019 - BMJ | Archives of Disease in Childhood