Jungnam Lee, Young‐Joo Jin, Seung Kak Shin, Jung Hyun Kwon, Sang Gyune Kim, Young Ju Suh, Yujin Jeong, Jung Hwan Yu, Jin‐Woo Lee, Oh Sang Kwon, Soon Woo Nahm, Young Seok Kim,
We compared the post-treatment overall survival (OS) and recurrence-free survival (RFS) between patients with Child-Turcotte-Pugh (CTP) class-A and single small (≤3 cm) hepatocellular carcinoma (HCC) treated by surgical resection (SR) and radiofrequency ablation (RFA).We retrospectively analyzed 391 HCC patients with CTP class-A who underwent SR (n=232) or RFA (n=159) as first-line therapy for single small (≤3 cm) HCC. Survival was compared according to the tumor size (≤2 cm/2-3 cm) and the presence of cirrhosis. ...
Tópico(s): Hepatitis B Virus Studies
2021 - Korean Association for the Study of the Liver | Clinical and Molecular Hepatology
Sang Kook Woo, Min Sang Kwon, Eun Lee,
Rings within rings: The total synthesis of (+)-neopeltolide was accomplished by employing an intramolecular Prins macrocyclization of an aldehydic homoallylic alcohol intermediate (see scheme).
Tópico(s): Chemical synthesis and alkaloids
2008 - Wiley | Angewandte Chemie International Edition
Sang Kook Woo, Min Sang Kwon, Eun Lee,
Kleine Ringe, große Ringe: Ein entscheidender Schritt bei der Totalsynthese von (+)-Neopeltolid war die intramolekulare Prins-Makrocyclisierung einer Aldehyd-Homoallylalkohol-Zwischenstufe (siehe Schema). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2008/z800386_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other ...
Tópico(s): Marine Sponges and Natural Products
2008 - Wiley | Angewandte Chemie
Han Cheol Lee, Sung Gyu An, Jae‐Hoon Choi, Tae Kun Lee, Jun Kim, June Hong Kim, Kook Jin Chun, Taek Jong Hong, Yung Woo Shin, Sang‐Kwon Lee,
Background Intravenous nicorandil infusion with percutaneous coronary intervention (PCI) has been reported to reduce reperfusion injury events and improve cardiac function in patients with acute myocardial infarction (MI). However, there is limited information on the use of intracoronary nicorandil. Methods and Results In the present study, 73 patients with acute ST segment elevation MI undergoing PCI were randomly assigned to the Nicorandil Group (n=37) or the Control Group (n=36). The composite endpoints ...
Tópico(s): Mechanical Circulatory Support Devices
2008 - Japanese Circulation Society | Circulation Journal
Sung‐Wook Kim, Min Ku Jeon, Hyun Woo Kang, Sang‐Kwon Lee, Eun-Young Choi, Wooshin Park, Sun-Seok Hong, Seung-Chul Oh, Jin‐Mok Hur,
Tópico(s): Metallurgical Processes and Thermodynamics
2016 - Springer Science+Business Media | Journal of Radioanalytical and Nuclear Chemistry
Dong‐Jun Lim, Eun‐Jee Oh, Chang‐Woo Park, Hyuk‐Sang Kwon, Eun-Ju Hong, Kye-Nam Yoon, Moo Il Kang, B.‐Y. Cha, Kyung-Woo Lee, Hwa‐Young Son, S.‐K. KANG,
Summary Hyperparathyroidism may be a precipitating factor important to the development of myelofibrosis: however, there has been only a few reports regarding myelofibrosis secondary to primary hyperparathyroidism. Recently, a rare case of pancytopenia caused by myelofibrosis in a 41‐year‐old woman who complained of general weakness and arthralgia presented to our clinical service. The patient was diagnosed with primary hyperparathyroidism with pancytopenia. Bone marrow biopsy revealed myelofibrosis. ...
Tópico(s): Hemoglobinopathies and Related Disorders
2007 - Wiley | International Journal of Laboratory Hematology
Co and Co–P catalysts electroplated on Cu in sulfate based solution without or with an addition of H2PO2− ions were developed for hydrogen generation from alkaline NaBH4 solution. The microstructures of the Co and Co–P catalysts and their hydrogen generation properties were analyzed as a function of cathodic current density and plating time during the electrodeposition. An amorphous Co–P electrodeposit with micro-cracks was formed by electroplating in the sulfate based solution containing H2PO2− ...
Tópico(s): Electrocatalysts for Energy Conversion
2006 - Elsevier BV | Catalysis Today
J Kim, S. Park, Hyun Mi Kang, Chul Woo Ahn, Hyuk-Sang Kwon, Jingchun Song, Y. J. Lee, K H Lee, Hongying Yang, Seung-Soo Baek, Soonil Yoo, S. H. Kim, Han Ju Kim,
In the present study, we examined the therapeutic potential of human amnion-derived insulin-secreting cells for type 1 diabetes. Human amniotic mesenchymal stem cells (hAMs) were isolated from amnion and cultivated to differentiate into insulin-secreting cells in vitro. After culture in vitro, the differentiated cells (hAM-ISCs) were intensively stained with dithizone and secreted insulin and c-peptide in a high-glucose-dependent manner. They expressed mRNAs of pancreatic cell-related genes, including ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2012 - SAGE Publishing | Cell Transplantation
Jihae Park, Do-Gyeong Lee, Seung-Woo Yeon, Hyuk-Sang Kwon, Jong-Hee Ko, Dong-Jin Shin, Han-Sol Park, Yong‐Soon Kim, Myun‐Ho Bang, Nam‐In Baek,
Tópico(s): Sirtuins and Resveratrol in Medicine
2011 - Springer Nature | Archives of Pharmacal Research
Yang‐Hyun Kim, Kyungdo Han, Jang Won Son, Seongsu Lee, Sang Woo Oh, Hyuk‐Sang Kwon, Soon‐Ae Shin, Yeon-Yong Kim, Won‐Young Lee, Soon Jib Yoo,
In Korea, the prevalence of obesity has steadily increased, and the socioeconomic burden of obesity has increased along with it. In 2015, the National Health Insurance Service (NHIS) signed a memorandum of understanding with the Korean Society for the Study of Obesity (KSSO), providing limited open access to its databases so that the status of obesity and obesity management could be investigated.Using NHIS databases, we analyzed nationwide population-based studies for obesity using the definition ...
Tópico(s): Diverse Approaches in Healthcare and Education Studies
2017 - Korean Society for the Study of Obesity | Journal of Obesity & Metabolic Syndrome
Woo‐Seok Kang, Sang‐Kwon Lee, Jung‐Hyuk Koh,
(Bi,Na)TiO3 (BNT) based ceramics have been extensively investigated for electronic device applications. BNT is ferroelectric material with ABO3 perovskite structure. BNT ceramics have high Curie temperature (Tc=320 °C) and remanent polarization (Pr=38 µC/cm2). Despite its relatively high coercive field (Ec=7.3 kV/mm) and low piezoelectric constant (d33=83 pC/N). Temperature and frequency dependent relative dielectric permittivity and loss tangent can play an important role in the device performance. To ...
Tópico(s): Microwave Dielectric Ceramics Synthesis
2015 - Elsevier BV | Ceramics International
Hae Won Yoo, Jun Yong Park, Sang Gyune Kim, Young Kul Jung, Sae Hwan Lee, Moon Young Kim, Dae Won Jun, Jae Young Jang, Jin Woo Lee, Oh Sang Kwon,
Abstract We prospectively investigated the changes of liver stiffness (LS) and the occurrence of hepatocellular carcinoma (HCC) after hepatitis C virus (HCV) eradication using direct antiviral agents (DAA) over three years. LS measurement using transient elastography and serum fibrosis surrogate markers before treatment and at 48, 96, 144 weeks after starting direct-acting antivirals (DAA) according to the protocol were evaluated. Patients were also compared with historical cohort treated with pegylated ...
Tópico(s): Hepatitis B Virus Studies
2022 - Nature Portfolio | Scientific Reports
Hyeonseo Song, Hajun Lee, Jaebyeong Lee, Jun Kyu Choe, Suwoo Lee, Jee Yoon Yi, Sunghoon Park, Jung‐Woo Yoo, Min Sang Kwon, Jiyun Kim,
Soft magnetic materials have shown promise in diverse applications due to their fast response, remote actuation, and large penetration range for various conditions. Herein, a new soft magnetic composite material capable of reprogramming its magnetization profile without changing intrinsic magnetic properties of embedded magnetic particles or the molecular property of base material is reported. This composite contains magnetic microspheres in an elastomeric matrix, and the magnetic microspheres are ...
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2020 - American Chemical Society | Nano Letters
Jaeseok Yi, Su Han Kim, Won‐Woo Lee, Sun Sang Kwon, SungWoo Nam, Won Il Park,
We fabricated flexible and transparent hydrogen gas sensors based on a palladium-decorated graphene mesh. Electron microscopy analysis confirmed that ~2–3 nm diameter Pd nanoparticles were uniformly dispersed on the graphene mesh surfaces. The sensors were highly transparent with an average optical transmission of >90% to visible light and they exhibited good electrical stability with a resistance change of 1.5% under a tensile strain of 1.1% in a cyclic bending-unbending test. Compared with graphene- ...
Tópico(s): Analytical Chemistry and Sensors
2015 - Institute of Physics | Journal of Physics D Applied Physics
Man-Geun Kim, Kyoung-Woo Jo, Hyuk-Sang Kwon, Won-Gun Jang, Young‐Sik Park, Jong‐Hyun Lee,
An on-axis laser Doppler vibrometer (LDV), where the direction of the incident beam is the same as the direction of the movement of the actuator, intrinsically offers an accurate dynamic measurement, although it cannot be currently applied to MEMS actuators with in-plane motion due to its limited access to the sidewall. The only currently available method is an off-axis LDV, which still shows serious measurement errors, depending on the target surface pattern of the device. In this paper, an on-axis ...
Tópico(s): Advanced MEMS and NEMS Technologies
2009 - Institute of Electrical and Electronics Engineers | Journal of Microelectromechanical Systems
Seok Hoo Jeong, Young Kul Jung, Jae Won Yang, Soo‐Jin Park, Jong Woo Kim, Oh Sang Kwon, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim,
Background/Aims Sustained virologic response (SVR) for the treatment of chronic hepatitis C (CHC) may differ with ethnicity due to differences in genetic traits. This study evaluated the efficacy of peginterferon and ribavirin, and the association between IL28B genotypes and the treatment efficacy in Korean CHC patients. Methods This was a retrospective cohort study using data from medical records. Eighty-five CHC patients were eligible for assessment of the efficacy of antiviral therapy, and 47 patients ...
Tópico(s): Liver Disease Diagnosis and Treatment
2012 - Korean Association for the Study of the Liver | Clinical and Molecular Hepatology
Na‐Ri Lee, Eun‐Kee Song, Kyu Yun Jang, Ha Na Choi, Woo Sung Moon, Keun-Sang Kwon, Ju Hyung Lee, Chang‐Yeol Yim, Jae‐Yong Kwak,
Tumor-infiltrating immune cells perform a crucial function in host immune reactions against diffuse large B-cell lymphoma (DLBCL). In this study, we have identified a subset of tumor-infiltrating FOXP3-positive regulatory T cells (Tregs) in the initial DLBCL biopsy specimens, and have evaluated their prognostic significance. Ninety six patients with DLBCL were evaluated retrospectively. The pattern of FOXP3 protein expression was evaluated using standard immunohistochemistry in paraffin-embedded tissue ...
Tópico(s): CAR-T cell therapy research
2008 - Taylor & Francis | Leukemia & lymphoma/Leukemia and lymphoma
Jae‐Yong Kwak, Na‐Ri Lee, Eun‐Kee Song, Kyu Yun Jang, Ha Na Choi, Woo Sung Moon, Keun-Sang Kwon, Ju Hyung Lee, Chang‐Yeol Yim,
Abstract Tumor infiltrating immune cells play an important role in host immune reactions against diffuse large B-cell lymphoma (DLBCL). In the present study, we have identified a subset of tumor infiltrating FOXP3-positive regulatory T cells (Tregs) in the initial DLBCL biopsy specimens and evaluated its prognostic significance. Ninety-six patients with DLBCL were retrospectively evaluated. Expression pattern of FOXP3 protein was examined using standard immunohistochemistry in paraffin-embedded tissue ...
Tópico(s): Immune Cell Function and Interaction
2007 - Elsevier BV | Blood
Nag‐Choul Choi, Jae‐Woo Choi, Kyu-Sang Kwon, Sang-Gil Lee, Soonjae Lee,
In this study, we quantified the attachment and detachment of bacteria during transport in order to elucidate the contributions of reversible attachment on bacterial breakthrough curves. The first set of breakthrough experiment was performed for a laboratory sand column using leaching solutions of deionized water and mineral salt medium (MSM) of 200 mM with reference to KCl solution by employing Pseudomonas putida as a model bacterium. In the second set of experiment, the ionic strengths of leaching ...
Tópico(s): Mine drainage and remediation techniques
2017 - Springer Nature | AMB Express
Ki‐Suk Kim, Hyang‐Ae Lee, Shin-Woo Cha, Myung-Sang Kwon, Eun Joo Kim,
Tópico(s): Neuroscience and Neural Engineering
2010 - Springer Nature | Archives of Pharmacal Research
Kyoung Min Kim, Young Jae Moon, See‐Hyoung Park, Hye Jeong Park, Sung Il Wang, Ho Sung Park, Ho Lee, Keun Sang Kwon, Woo Sung Moon, Dong Geun Lee, Jung Ryul Kim, Kyu Yun Jang,
DNA damage response (DDR) molecules are protective against genotoxic stresses. DDR molecules are also involved in the survival of cancer cells in patients undergoing anti-cancer therapies. Therefore, DDR molecules are potential markers of cancer progression in addition to being potential therapeutic targets. In this study, we evaluated the immunohistochemical expression of PARP1, γH2AX, BRCA1, and BRCA2 and their prognostic significance in 112 cases of soft tissue sarcoma (STS). The expression of ...
Tópico(s): Cell death mechanisms and regulation
2016 - Public Library of Science | PLoS ONE
Jin‐Woo Jung, Hyejin Je, Sang‐Kwon Lee, Youjung Jang, Jihye Choi,
Shear wave elastography (SWE) induces lateral shear wave through acoustic pulses of the transducer and evaluates tissue stiffness quantitatively. This study was performed to evaluate feasibility and reproducibility of two-dimensional shear wave elastography (2D SWE) for evaluation of tissue stiffness and to examine technical factors that affect shear wave speed (SWS) measurements in adult dogs. Nine healthy, 2 year-old, adult beagles with the median weight of 9.8 kg were included. In this prospective, ...
Tópico(s): Tendon Structure and Treatment
2020 - Frontiers Media | Frontiers in Bioengineering and Biotechnology
Jang Won Son, Eun-Hee Jang, Meekyoung Kim, Ki‐Hyun Baek, Ki‐Ho Song, Kun‐Ho Yoon, Bong‐Yun Cha, Ho‐Young Son, Kwang‐Woo Lee, Hanjoong Jo, Hyuk‐Sang Kwon,
Aim: The aim of this study was to evaluate the association between the circulating BMP-4 levels and atherosclerosis in patients with Type 2 diabetes. Material & methods: Serum BMP-4 levels were measured in 174 diabetic patients, and the degree of atherosclerosis was assessed by measuring the carotid intima-media thickness and the cardio-ankle vascular index. Results: Serum BMP-4 levels were inversely correlated with systolic blood pressure, triglycerides, free fatty acids, cardio-ankle vascular index ...
Tópico(s): Biomarkers in Disease Mechanisms
2011 - Future Medicine | Biomarkers in Medicine
Seung-Woo Yeon, Youngsang You, Hyuk-Sang Kwon, Eun Hee Yang, Jung-Su Ryu, Byung Hwa Kang, Jae‐Hoon Kang,
In order to find new application fields for probiotics and their fermented products, we explored fermented milks cultured with various probiotic strains improving amyloid precursor protein (APP) metabolism in Alzheimer’s disease. In cell-based assay using wild type of APP and β-secretase over-expressing cell, the ethanol precipitates of the fermented milk cultured with Lactobacillus helveticus IDCC 3801, induced a strong decrease of APPβ level in amyloidogenic pathway toward β-amyloid production ...
Tópico(s): Alzheimer's disease research and treatments
2010 - Elsevier BV | Journal of Functional Foods
Stephan Pflugmacher, Sandra Kühn, Sang Hyup Lee, Jae‐Woo Choi, Seungyun Baik, Kyu-Sang Kwon, Valeska Contardo‐Jara,
The protection and reasonable use of freshwater is one of the main goals for our future, as water is most important for all organisms on earth including humans. Due to pollution, not only with xenobiotics, but also with nutrients, the status of our water bodies has changed drastically. Excess nutrient load induces eutrophication processes and, as a result, massive cyanobacterial blooms during the summer times. As cyanobacteria are known to produce several toxic secondary metabolites, the so-called ...
Tópico(s): Aquatic Ecosystems and Phytoplankton Dynamics
2015 - Scientific Research Publishing | American Journal of Plant Sciences
Jae‐Woo Choi, Kyu-Sang Kwon, Soonjae Lee, Byungryul An, Seok Won Hong, Sang-Hyup Lee,
Tópico(s): Adsorption and biosorption for pollutant removal
2014 - Springer Science+Business Media | Water Air & Soil Pollution
Young Kul Jung, Ji Hoon Kim, Sung‐Min Ahn, Jae Won Yang, Soo‐Jin Park, Jong Woo Kim, Jong Eun Yeon, Oh Sang Kwon, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim, Kwan Soo Byun,
Background: Genetic variations in interleukin 28B (IL28B) have been strongly associated with a sustained virological response (SVR) in European and African-American patients. Genetic variation of IL28B was investigated in healthy controls and chronic hepatitis C (CHC) patients, and the treatment response in the CHC patients was analyzed according to IL28B polymorphism in the Korean population. Methods: IL28B polymorphisms (rs12979860 and rs8099917) were studied in 200 healthy controls and in 167 CHC ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2013 - Lippincott Williams & Wilkins | Journal of Clinical Gastroenterology
So Young Kwon, Sang Hoon Park, Jong Eun Yeon, Sook‐Hyang Jeong, Oh Sang Kwon, Jin Woo Lee, Hong Soo Kim, Yeon Seok Seo, Young Seok Kim, Joo Hyun Sohn, Hyung Joon Yim, Jong Young Choi, Myung Seok Lee, Young Oh Kweon, Jae Youn Cheong, Haak Cheoul Kim, Heon Ju Lee, Soon Koo Baik, Hyonggin An, Kwan Soo Byun,
The aim of this study was to investigate the clinical characteristics of acute hepatitis A during a recent outbreak in Korea. Data of patients diagnosed with acute hepatitis A from 2007 to 2009 were collected from 21 tertiary hospitals retrospectively. Their demographic, clinical, and serological characteristics and their clinical outcomes were analyzed. A total of 4,218 patients (mean age 33.3 yr) were included. The median duration of admission was 9 days. The mean of the highest ALT level was 2, ...
Tópico(s): Hepatitis B Virus Studies
2014 - Korean Academy of Medical Sciences | Journal of Korean Medical Science
Jang Won Son, Eun-Hee Jang, Meekyoung Kim, In Tae Kim, Young‐Jung Roh, Ki‐Hyun Baek, Ki‐Ho Song, Kun‐Ho Yoon, Bong‐Yun Cha, Kwang‐Woo Lee, Ho‐Young Son, Hyuk‐Sang Kwon,
We aimed to evaluate the association between diabetic microangiopathy and subclinical atherosclerosis as a marker of cardiovascular disease (CVD) risk in patients with newly diagnosed type 2 diabetes.A total of 142 newly diagnosed type 2 diabetics who were free from CVD underwent evaluation of diabetic microangiopathy. Subclinical atherosclerosis was assessed by measuring carotid intima-media thickness (IMT), and the 10-year absolute risk of CVD was estimated using the UK Prospective Diabetes Study ( ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2010 - Elsevier BV | Diabetes Research and Clinical Practice
Eun Sook Kim, Hyuk‐Sang Kwon, Chul Woo Ahn, Dong Jun Lim, Jeong Ah Shin, Seung‐Hwan Lee, Jae‐Hyoung Cho, Kun‐Ho Yoon, Moo Il Kang, Bong Yun, Hwa‐Young Son,
To determine the relationship between serum uric acid, metabolic syndrome (MetS), and albuminuria in type 2 diabetic patients.A total of 504 Korean patients with type 2 diabetes aged 57.3 years were retrospectively evaluated for clinical histories, anthropometric measurements, and biochemical studies. Urinary albumin excretion (UAE) was measured by a 24-h urine collection.Prevalence of MetS increased according to the quartiles of uric acid levels (≤3.7, 3.8 to 4.5, 4.6 to 5.5, and >5.5 mg/dl; 52.1%, ...
Tópico(s): Liver Disease Diagnosis and Treatment
2010 - Elsevier BV | Journal of Diabetes and its Complications