John MacDonald, Liz Dolan, Edward Owen, Helen Johnstone, Iain R. Webb, Steve Jones, Erica Wanger, Mary Killen, Sue Masterman, Edward Gorman Ireland Correspondent, Jane MacQuitty, Simon Barnes, Alison Roberts Arts Reporter, Jan Morris, David Miller Chief Sports Correspondent, John Diamond, Karen Woolfson, David Grundy, Chartered engineer, Derek Nimmo, Norman Howell, Angela MacKay, Philip Howard, James Bone and David Watts, George Sivell, Hylton, Clive Davis, Carol Leonard, Richard Streeton, Fred Barschak, Neil Bennett, Banking Correspondent, James Prince, J. K., Tom Walker, Gerald Davies, Joe Joseph, Francesca Greenoak, David Rowland, Mitchell Platts, Golf Correspondent, John Hollandan and our Foreign Staff, Tony Bianchi, Louise Taylor, Raymond Kennee, Chess Corespondent, Michael Binyon, Diplomatic Editor and Tim Judah, Geoffrey Robinson, Robin Young, Patrick Scrivenor, Michael Clark, B. E. Danton, Michael Hamlyn, Aubrey Newman, David Fordham, Frances Bissell, Marcus Binney Architecutre Correspondent, Alber Dormer, Russell Johnston, David Hands, Charles Bremner, Candy and Dennis Atherton, Annie Rankin, Nigella Lawson, Michael Binyon Diplomatic Editor, Derwent May, Conor Cruise O'Brien, E. A. Foster, Charles W. Morland, Xa Younger, Colin Campbell Mining Correspondent, James Hepburn, Melinda Wittstock Media Correspondent, Josephine Robinson (Chairman), Philip Webster, Chief Political Correspondent, Eric Griffiths, Barbara McSweeney, Patrick Cormack, Lindsay Cook, Money Editor, Raymond Keene, David Allsop, Brian Hebblethwaite, David Flussfeder, Joe Steeples, N. L., Norman Lebrecht, Michael F. H. Banks, Neil Bennett Banking Correpsondent, Barry Pickthall, Brain Alderson, Tom Walker and Philip Webster, Ian Ross, Kate Alderson, David Hands Rugby Correspondent, Christopher Irvien, Martin Waller, Deputy City Editor, John Goodbody, Edward Gorman, Ireland Correspondent, Nick Nuttall, Technology Correspondent, Sara McConnell, Corylus, Rachel Kelly Local Government Correspondent, Colin Narbrough, Economics Correspondent, Graham Paterson, Srikumar Sen Boxing Correspondent, Richard Evans Racing Correspondent, Christopher Hawtree, Sarah Jane Checkland Art Market Correspondent, C. Eliot-Choen, Alan Franks, Caitlin Moran, Alan Lee, Ruth Padel, Ben MacIntyre, Ben Helfgott, Alice Walker, Sheila Morley, Lay Advocate, Richard Beeston, R. T. Beckwith, Michael Phillips, Benedict Nightingale and Jeremy Kingston, Nadine Mesiner, John Deverill, David Sinclair, Simon Jenkins, Linda Grant, William Cash, Lindsay Cook Weekend Money Editor, Christopher Elliott, Sydnewy Rriskin, Alan Coren, Rabbi Dr Jonathan Romain, Jonathan Meades, Nicolas Wapshott, Jill Sherman, Political Correspondent, David Powell, Anne McElvoy, Kari Kinght, Rosanna Greenstreet, Colin Campbell, John O'leary, Education Correspondent, Jody Tresidder, David Hands, Rugby Correspondent, Clement Freud, Andrew Turner (Director), Sam Kiley, Africa Correspondent,
... of circus is teaching acrobatic skills and confidence, Xa Younger reports Where to join the new circus ...
1992 - Gale Group | TDA
Ningning Zhou, Juanfang Zhou, Yanpeng Lu, Defang Xu, Xingliang Liu,
... novel D-A type tetraphenylethene-based fluorophores, named XA-BZ-TPE and XA-DCE-TPE, were designed and synthesized. Both fluorophores ... induced emission (AIE) behavior. The AIE factors for XA-BZ-TPE and XA-DCE-TPE were >243 and 12, respectively. Notably, both XA-BZ-TPE and XA-DCE-TPE display high-contrast mechanofluorochromic (MFC) properties. ... to 0.484 and 0.278, respectively, for XA-BZ-TPE and XA-DCE-TPE. In XA-BZ-TPE and XA-DCE-TPE, according to the analysis using PXRD, ...
Tópico(s): Molecular Sensors and Ion Detection
2023 - Elsevier BV | Dyes and Pigments
Liz Dolan, Derek Jennings, Jon Ashworth, Paul Heiney, Nicholas Wood, Political Correspondent, Anatol Lieven, Patricia Davies, Mary Killen, David Bull, Director, Barry Trowbridge, Jane MacQuitty, Simon Barnes, Alan N. Mundy, Bill Frost, Andrew Longmore, Sheila Gunn, Political Correspondent, Anna Shovlar, John Diamond, Philip Howard, Anthony Procopi, Ian Murray, Simon D. Turton, Clive Davis, Ali Mohamed Osman Yassin, Albert Dormer, Carl Mortished, Kevin Eason, Motoring Correspondent, Anthony Caillard, Tom Walker, Colin Narbrough, World Trade Correspondent, Chris Metz, Philip Bassett Industrial Editor, Francesca Greenoak, Martin Fletcher, Cyril Bryan, Ruth Gledhill, Religion Correspondent, Nicholas Wood Political Correspondent, Robert Wright, Ruth Gledhill, Martin Fletcher us Editor, John Campbell-Kease, Alexander S. Hoare, Rachel Kelly, Rob Hughes Football Correspondent, Richard Evans, Racing Correspondent, Libby Purves, Nick Nuttall Technology Correspondent, Robin Young, Peter Millar, Louise Hidalgo, Nicholas Watt, John Young, Michael Hamlyn, Reuter, Peter Riddell and Jonathan Prynn, Keith Pike, Frances Bissell, Daisy Lewis, Sarah Bagnall, Peter Carver (Director General), David Wickens, Xa Younger, Lindsay Cook, John Woodcock, Lindsay Cook Money Editor, Kari Knight, David Miller, Alison Roberts, Catherine Sampson, Anthea Streeter, Lindsay Cook, Money Editor, Sara McCONNELL, Raymond Keene, Peter Carter-Ruck Libel lawyer, Peter Davalle, Alan Lee, Cricket Correspondent, Raymond Keene, Chess Correspondent, John Stokes, Cheryl Taylor, Paul Wilkinson, Michael Evans, Defence Correspondent and our Foreign Staff, John Morris, Matthew d'Ancona, Richard Evans, Thelma D. Taylor, Moy McCrory, Heather Kirby, David Powell, Athletics Correspondent, Philip Bassett and Nicholas Wood, Janet Caldwell, Theresa Buck, Michael Hornsby, Agriculture Correspondent, Kate Alderson, David Hands Rugby Correspondent, Cora Stamps, Martin Waller, Deputy City Editor, Christopher Thomas, Simon Winchester, Mary Ann Sieghart, Jack Dee, M. K. Ewans, Sara McConnell, Nick Nuttall, Technology Correspondent, Keith Brace, Richard Evans Racing Correspondent, Michael Seely, Caitlin Moran, P. Vincent (Chairman), Alan Lee, Walter Gammie, Ben MacIntyre, Peter Victor, Keith Hampson, Graham Mather, Simon Jenkins, Philip Pangalos, Stephen Pettitt, Lindsay Cook Weekend Money Editor, Martin Waller, Kate Bassett, Eithne Power, Benedict Nightingale, Jonathan Meades, Michael Evans Defence Correspondent, Robin Burgess, Anne McElvoy, Mark Cole, John Phillips, Timothy Russ, Ronald Hooberman, John O'leary, Education Correspondent, B. E. Brown, Paddy Burt, Sarah Woodward, George Sivell City Editor, Christopher Irvine,
... ideal holding is not lazing on a beach, Xa Younger reports, but happily slogging away on a ...
1993 - Gale Group | TDA
Dominique Lasne, M. Toussaint‐Hacquard, Céline Delassasseigne, Anne Bauters, Claire Flaujac, Philippe Savard, C. Mouton, Emmanuel de Maistre, Alain Stépanian, Valérie Eschwège, Maxime Delrue, Jean‐Louis Georges, Antoine Gros, Alexandre Mansour, G Leroy, Romain Jouffroy, Matthieu Mattei, Antoine Beurton, Adeline Pontis, Marie Neuwirth, Fabienne Nédelec-Gac, Thomas Lecompte, Emmanuel Curis, Virginie Siguret, Isabelle Gouin‐Thibault,
... lead to discrepancies between unfractionated heparin (UFH) anti-Xa levels. To evaluate the extent of the effect ( ... of the blood collection tubes, on UFH anti-Xa levels, in various clinical situations (NCT04700670). We prospectively ... collected into citrated and CTAD tubes. Chromogenic anti-Xa assays were centrally performed, using seven reagent/analyzer ... including two without DS. The association between anti-Xa levels and covariates was tested using a linear mixed-effects model. We analyzed 4,546 anti-Xa values from 165 patients. Median anti-Xa levels ...
Tópico(s): Acute Myocardial Infarction Research
2023 - Thieme Medical Publishers (Germany) | Thrombosis and Haemostasis
... Chapter IX Friendly Advice, The Wild Hunteress Chapter Xa Classic Land, Willie Gray; or, the Wreck of ...
1867 - Gale Group | NCCO British Theatre
Ravi Taneja, Daniel J. Szoke, Zachary Hynes, Philip M. Jones,
... gold standard assays of anti-IIa and anti-Xa activity. Secondary objectives were to evaluate whether the ... for activated clotting time and anti-IIa and -Xa activity.Following a mean (standard deviation) cumulative heparin ... patients showed complete neutralization of anti-IIa and -Xa activity at the first sampling point (150 mg ... clotting time correlated well with anti-IIa and -Xa activity.The protamine:heparin ratio required to neutralize ... sufficient to neutralize both residual anti-IIa and -Xa activity in most patients. Larger studies are necessary ...
Tópico(s): Intramuscular injections and effects
2022 - Springer Science+Business Media | Canadian Journal of Anesthesia/Journal canadien d anesthésie
... etc. Legal Department Publications. 01/06/1946. HA10-XA. Pamphlet; Newspaper cutting. Table; Cartoon. English; German. Wiener ...
1946 - Gale Group | PWE
Kevin Verhoeff, Kendra Raffael, Matthew Connell, Janice Y. Kung, Matt Strickland, Arabesque Parker, Ram Venkatesh Anantha,
... trauma patients. Is there any association between anti-Xa and VTE? Does dose adjustment improve prophylactic anti-Xa rates? Does dose adjustment improve anti-Xa adequacy and VTE compared with standard dosing?Systematic ... evaluated low molecular weight heparin chemoprophylaxis, reported anti-Xa level, and evaluated more than one outcome. Data ... method. Analysis 1 compared patients with peak anti-Xa of 0.2 IU/mL or greater or ... mL or greater to those with lower anti-Xa using VTE as the primary outcome. Analysis 2 ...
Tópico(s): Trauma, Hemostasis, Coagulopathy, Resuscitation
2022 - Lippincott Williams & Wilkins | Journal of Trauma and Acute Care Surgery
Srikumar Sen, Boxing Correspondent, Widget Finn, Jon Ashworth, Sheila Gunn, Political Reporter, David Tytler, Peter Green, Carol Reed, Roger Preston, Gordon Allan, David Rhys Jones, Jinathan Green, Sheridan Morley, Philip Howard, James Bone, Chris Eliou, Joseph Williams, Clive Davis, Dessa Trevisan and Richard Bassett, Mandarin (Michael Phillips), Carol Leonard, Howard French, Colin Narbrough Economics Correspondent, Gerald Davies, Philip Bassett Industrial Editor, Bernard Levin, Brian James, Bryan Stiles, Stuart Jones, Victor Walker, Peter Davenport, Bruce Clark, Angeliki Moynihan, Raymond Keene Chess Correspondent, Louise Taylor, Nick Nuttall Technology Correspondent, Peter Bills, Robin Young, Nicholas Watt, Jenny MacArthur, Michael McCarthy, Environment Correspondent, John O'Leary, John Young, Anatole Kaletsky, Douglas Broom, Local Government Correspondent, David Hands, Our Irish Racing Correspondent, G. W. Hunt, Robert Gieve (Vice-chairman), John Percival, Philip Bassett, Industrial Editor, Dick Howard, Jennifer Fowler, Stanley Manchester, Simon Tait, George Rae, John Woodcock, Wolfgang Munchau, Martin Hoyle, Sydney Friskin, Dennis Signy, Joy Hill, David Miller, Philip Webster, Chief Political Correspondent, Nicolas Soames, Ian Murray and Christopher Walker, Andrew McEwen, Diplomatic Editor, Susan Ellicott and Andrew McEWEN, David Powell Athletics Correspondent, Jonathan Prynn, Paul Griffiths, Steve Acteson, Clyde Binfield, Richard Evans, Claire Lyon, Christopher English (Secretary to the trustees), John Blunsden, Richard Owen, Wolfgang Munchau, European Business Correspondent, John Bell, Barry Pickthall, Roger Boyes, Michael Theodoulou and Christopher Walker, Ian Ross, Paul Adams, Ronald Butt, John O'leary, Higher Education Correspondent, John E. Smith, Andrew Lockley, Keith MacKlin, David Hands Rugby Correspondent, Christopher Thomas, David Young, Wayland Kennet, Colin Narbrough, Economics Correspondent, Matthew Parris, Mary Dejevsky, Walter Gammie, Lessware, Aylmer, Alan Lee Cricket Correspondent, David Young and Ray Clancy, Philip Webster, Nadine Meisner, Philip Pangalos, Martin Waller, Michael Horsnell, Quentin Cowdry, Home Affairs Correspondent, Mohammed B. A. Rizvi, Vivien Tomlinson, John Currie, Vince Wright, Louise Byrne, John Hoskyns, Harvey Elliott Air Correspondent, D. M. L. Alexander, Peter Robinson, J. R. R., Anna Franklin, Thanos Veremis, Nicholas Ridley, Keith Joseph, M. J. Bissmire,
... to date Sea yields secrets of ancient trade XA Greece Elizabeth Hunt New Year, New Start Educational ...
1990 - Gale Group | TDA
Trần Minh Phú, Trinh Van Loc, Tran Le Cam Tu, Trần Minh Phú, Phạm Minh Đức, Hứa Thái Nhân, Phạm Thanh Liêm,
... dose of astaxanthin (As), canthaxanthin (Ca), and xanthophyll (Xa) pigments individually and in combination. In the first ... comprised of three diets of As, Ca, and Xa at a 100 mg/kg rate of supplementation, ... and three diets combinations of As + Ca, As + Xa, and Ca + Xa at a supplement rate of 50 mg + 50 ... L* (Lightness) and a* (redness) values in the Xa diet were significantly lower than other treatments, while ... was found in the fish fed with the Xa diet. The Xa diet was selected for the second experiment. This experiment consisted of four Xa supplemented diets at rates of 25, 50, 75, ...
Tópico(s): Reproductive biology and impacts on aquatic species
2022 - Multidisciplinary Digital Publishing Institute | Fishes
Jonathan Northcroft, Dan Mitchell, Waldemar Januszczak, John Dugdale, Patrick French, Matthew Wall, Julian Corolett, Barbara Hall, Nigel Botherway, Will Young, Dominc Rushe, Clare Ward MP, Fred Redwood, David Brown, Helen Davies, Nicholas Rufford, Rob Hughes, Graeme Wright, John Peter, V S, Emma Moore, Rebecca Abrams, Teresa Keane, Amanda Ursell, Jonathan Miller, David Pryce-Jones, J D, Susan d'Arcy, Lucy Adams, Frank Whitford, Nicholas Coleridge, Steve Bord, Sam Gilpin, Kathryn Cooper, Mia Ogden, David Smith, Humphrey Carpenter, Tim Richards, Ian Murray, Rory Godson, David Cracknell Political Editor, Nick Pitt, Frederic Raphael, Neil Wormald, E P, Andrew Sullivan, Loe Lovejoy, Don Pettingale, Guy Dennis, Lynne Truss, Neil Davy, Leslie Fraser-Mitchell, Kathy Brewis, Mark Blumberg, Tony Allen-Mills, Simon Wilde, Martin James, Anthony Sattin, Robert Winnett, Irwin Stelzer, Adrian Furnham, Peter Wilson, Rosie Millard, Lawrence Dallaglio, David Dougill, Sir Nigel Hawthorne, John Arlidge, Thrasy Petropoulos, H C, David Hewson, Adam Duritz, Cally Law, Rakesh Rawal, Hugh Canning, Alasdair Reid, Margarette Driscoll, Graham Duffill, Jeremy Clarkson, Andrew Stone, Trevor Drury, Edward Porter, Stewart Lee, Victoria Segal, Lisa Miller, Fiona Berry, Helen Kenny, Anita Chaudhuri, John O'Donnell, Nick Caln, Travis Elborough, Liz Edwards, George Perry, Karena Batstone, Nick Gardner, Peter Parker, Mike Laws, Paul Ham, Roger Eglin, Paul Donovan, Kathryan Cooper, Alastair Hendy, Chris Woodhead, Stan Labovitch, Lucinda Kemeny, Jasper Gerard, Derek Clements, Michael Woodhead, Paul Driver, John Humphrys, Nicholas Hellen, Richard Brooks, Johan Cruyff, Ian Hawkey, Shelley Von Strunckel, Alex Clark, Christopher Morgan, David Leppard, Lynne Franks, Paul Durman, Mark Edwards, Keith Rider, Sarah Gracie, George Kelly, Alan Allbright, Tilly Bagshawe, David Lawrenson, Andy Knett, Susan Clark, Angus Deayton, Nick Raynsford Mp, Danny O'Brien, Phil Baker, Christina Patterson, Victoria O'Brien, Raymond Keene, Joe Lovjoy, Gareth Huw Davies, David Cracknell, Cosmo Landesman, Zoe Brennan, Robbie Hudson, Marie Colvin, Diana Wright, Norman Parkinson, David Orr, Stephen Jones, Dominic O'Connell, Alexis Giles, Richard Evans, Uzi Mahnaimi, Nick Cain, Michael Wright, Peta Bee, Jonathan Davies, Luci Hoe, M J, Lois Rogers Medical correspondent, Nick Rennison, Damaris Graham, Miranda Seymour, David Walsh, Caroline Gascoigne, David Lodge, Trevor Lewis, Jack Grimston, Colin McDowell, Bryan Appleyard, Lois Rogers Medical Correspondent, Stephen Armstrong, John Elliott, John O'brien, Richard Woods, Danny Roth, William Burrows, Rory Godson Business Editor, John Lloyd, Maurice Chittenden, Les Snowdon, Matthew Williamson, Nick Hanna, Stephen Jay Gould, Richard Brooks Arts Editor, Tom Brett, Richard Rae, Mark Franchetti, Ray Hutton, James Hughes, Martin Ivens, Ian G Mace, Frank Fitzgibbon, Winner Dinners, Huw Richards, Alexandra Dawe, Jeff Bell, Hazel Prouse, Ria Higgins, Michael Sheridan, Godfrey Smith, Barry Collins, John Waples, Paul Rowan, Hunter Davies, Marc Zakian, A A Gill, Matthew Campbell, R Tomlinson, Natalle Graham, Nick Fielding, James Beechey, Claudia Croft, Maria McErlane, Jonathan Leake Science Editor, Jonathan Calvert, Cherry Norton, Sally Kinnes, Janet Crawford, Naomi Caine, David Wickers, Nigel Powell, Jeremy Lazell, Mark Hodson, Andrew Frankel, Graham Norwood, Elizabeth Buchan, Joe Lovejoy, Jonathan Futrell, Rupert Steiner, Hugh Pearman, Ian Hawkey European football correspondent, Dan Cairns, David Harbord, David Smith Economics Editor, Tom Deveson, Mrs Mills, Simon Crerar, Sarah Baxter, Kate Spicer, Essop Pahad Minister in the Presidency, Matthew Goodman, India Knight, Steve Grant, Nicola Gill, Kingston Smith, Simon Howard, Dan Pearson, Toyah Wilicox, Dominic Rushe, Karen Robinson, Peter Stanford,
... Week Greenspan's Taming of the Wave Francors-Xa… Bestselling Business Books Richard, a man with a ...
2002 - Gale Group | Sunday Times HA GDA
Ruben Rhoades, Ron Leong, Jason Kopenitz, Brandi Thoma, Lydia McDermott, Joseph Dovidio, Shannon Barletti, Jerald Z. Gong, H. Todd Massey, Steven E. McKenzie, J. Eduardo Rame, Nawar Al‐Rawas,
... records by the study investigators. The UFH anti-Xa assay was performed on ACL TOP 500 using Liquid Anti-Xa assay kit by HemosIL, which does not contain ... s, while therapeutic values for UFH by anti-Xa correlation were 58–85 s. The timing of ... that simultaneous pairs of aPTT and UFH anti-Xa could be studied, and association with other laboratory ... each simultaneous pair, the goal aPTT or anti-Xa range was recorded based on the heparin order ... concordance was made clinically for each aPTT-anti-Xa pair. If both an aPTT and anti-Xa ...
Tópico(s): Sepsis Diagnosis and Treatment
2021 - Elsevier BV | Thrombosis Research
J. E. C. WELLDON, Bishop; Dean of Manchester. T. FOWELL BUXTON, Bt., G.C.M.G. E. GROSE HODGE, Prebendary of St. Paul's. EDMUND S. HANBURY, Chairman and Treasurer., G. HAY MORGAN, Hon. Sec. of the Nonconformist, (Cheers.) H. H. ASQUITH., T. C. FRY., 10, Chesterfield-street, W., March 4. ARTHUR LEE., A MAGISTRATE. March 5., CAROLINE A. LYTTELTON., JOHN HY. JOHNSON, Secretary., T. A. LACEY., W. F. COBB, D.D., HUGH E. HOARE., F. E. MARSHALL., A WOMAN JOURNALIST AND SUBSCRIBER March 4. TO THE TIMES., A. V. DICEY., E. C. CLARK., W. T. STEAD., L. A. ATHERLEY-JONES., H. M. HYNDMAN., A. H. HEATH., EDWARD G. FAIRHOLME, Secretary., ROBERT L. G. VASSALL., C. W. TRURON., EDWARD CLARKE. Royal Courts of Justice, March 5., P. CHALMERS MITCHELL., J. CATHCART WASON., JOHN ROCHE, Secretary., JONATHAN HUTCHINSON., BY JOHN B. SPARKS., ROBERT THOMSON., BY VIATOR.,
... Mails. Outward Mails., " P. and O.-s. P.xA, London for Sydney, arrived, Shipping Facilities At Port ...
1912 - Gale Group | TDA
Steffany N. Nguyen, Melanie Ruegger, Eric Salazar, Diane Dreucean, Alexandra W. Tatara, Kevin R. Donahue,
Although not routinely recommended, anti-Xa level monitoring for apixaban or rivaroxaban may be useful in certain clinical scenarios. There are currently no laboratory standards, therapeutic ranges, or proven correlation between anti-Xa levels and clinical outcomes.This study describes the utilization, application, and association of anti-Xa levels with clinical outcomes in patients receiving apixaban ... apixaban or rivaroxaban with at least one anti-Xa level ordered subsequent to administered doses. The primary ...
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
2021 - SAGE Publishing | Journal of Pharmacy Practice
Kay Marles, Phil Yates, Liz Dolan, Francesea Greenoak, Paul Heiney, Tony Travers, Edward Gorman Ireland Correspondent, Jane MacQuitty, Simon Barnes, Richard Ford, Home Correspondent, Rose Wild, Alison Roberts Arts Reporter, Jan Morris, Roland Rench, Tim Judah, John Diamond, Angela MacKay, Peter Burnham, Philip Howard, Blake, Hylton, Clive Davis, Lynne Truss, Richard Streeton, Adrian Hastings, Patrick Stoddart, Matthew D'ancona, Education Correspondent, Saba Risaluddin, J. J., Joe Joseph, Martin Fletcher, Philip Willan and Nigel Hawkes, Mitchell Platts, Golf Correspondent, Richard Dunn, Anthony Gardner, Alan Lorimer, Patricia Tehan, Louise Taylor, Ruth Gledhill Religion Correspondent, Arthur Leathley and Julia Llewellyn Smith, Peter Ackroyd, Nick Nuttall Technology Correspondent, Richard Ford Home Correspondent, Robin Young, Jenny MacArthur, Rachel Kelly, Property Correspondent, Michael Clark, H. G. Wells, Philip Robinson, Michael Hamlyn, Frances Bissell, P. D. Wright, Russell Johnston, Charles Bremner, R. E. Killpartrick, Neil Bennett Banking Correspondent, Derwent May, Barbara Reid, Helen Johnstone and Stewart Tendler, Paul Wheeler, Ralph Horwitz, Christina Speight, Sally Jones, Nicole Swengley, Xa Younger, George Brock, Janet Daley, Sydney Friskin, Lindsay Cook Money Editor, R. F. Ackary, Philip Webster, Chief Political Correspondent, Michael Hamlyn Sam Kiley, Africa Correspondent, and Reuter, Anne McElvoy and our Foreign Staff, Trevor Huddleston, Lindsay Cook, Money Editor, Raymond Keene, Jonathan Prynn, Raymond Keene, Chess Correspondent, Richard Ford and Stewart Tendler, June Ducas, Arnold Rosen, Matthew d'Ancona, Richard Evans, David Ekserdjian, David Powell, Athletics Correspondent, Peter Porter, Barry Pickthall, Nigel Hawkes, Science Editor, Gweneth Cannon, Kate Alderson, Hugo Gryn, Jamie Dettmer, Robin Stacey, Ian McMillin, Martin Waller, Deputy City Editor, Rodney Pattisson, Joanna Pitman, T. A. Mansfield, Sara McConnell, Colin Narbrough, Economics Correspondent, Srikumar Sen Boxing Correspondent, Stephen Romer, Frank Jeffery, Caitlin Moran, John Horsbrugh-Porter, Michael Foot, Ben MacIntyre, Sarah Jane Checkland, Andy Martin, Richard Beeston, Denis Peel, Michael Phillips, Tom Walker and Arthur Leathley, David Sinclair, Philip Pangalos, Stephen Pettitt, Ben Lynfield, Lindsay Cook Weekend Money Editor, Alan Coren, Sarah Lee, Benedict Nightingale, Tom Rhodes, Jonathan Meades, B. Hall, Jill Sherman, Political Correspondent, Arthur Leathley, Valerie Grove, Brian G. Marsden, Fiona Beckett, Matthew Bond, Rosanna Greenstreet, Anthony Howard, Judy Froshaug, David Hands, Rugby Correspondent, Zaki Badawi, Clement Freud, Christopher Irvine,
Bonfire Night Major wins back waverers with Maastricht-free motion US facing frantic last three days Index Weekend Minicab bomb rocks Downing St Saturday ...
1992 - Gale Group | TDA
Isabelle Malhamé, Maha Othman, Patricia Casais, Rohan D’Souza, Rachel M. Wald, Candice K. Silversides, Mathew Sermer, Nadine Shehata,
... were made according to pregnancy weight, peak anti-Xa (n = 22, 29%), peak and trough anti-Xa (n = 20, 26%), peak anti-Xa only (n = 20, 26%), or pregnancy weight only ( ... 14%). Hematology/thrombosis specialists predominantly used peak anti-Xa (n = 15, 31%). Dosage adjustments did not vary ... to determine the starting dose of LMWH, anti-Xa peak and trough levels were used to guide ... Supplementary Appendix, respectively. Most respondents reported using anti-Xa levels for dose adjustment of LMWH. The monitoring of trough and peak anti-Xa levels has been recommended by the European Society ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2021 - Elsevier BV | Journal of Thrombosis and Haemostasis
Floris T.M. Bosch, Matteo Candeloro, Nicola Potere, Ettore Porreca, Marcello Di Nisio, Pieter W. Kamphuisen,
... Scholar]. Direct oral anticoagulants (DOACs), comprising the factor-Xa inhibitors apixaban, edoxaban and rivaroxaban and the thrombin ... Table 2). All included patients were using factor-Xa inhibitors and where on a therapeutic dose. Six ... started anticoagulant treatment within 14 days of anti-Xa measurement. The indication for anticoagulation therapy was venous ... 2DOAC plasma levels and characteristics per patient.Factor-Xa inhibitorDoseIndicationNew/chronic usersDXM dose*Days of DXM*AgeSexWeight, ... mg/l‡Other P-gp/CYP3A4 inducers/inhibitorsFactor-Xa trough levelTrough level §Factor-Xa peak levelPeak level § ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Elsevier BV | Thrombosis Research
Richard Descamps, Mouhamed Djahoum Moussa, Emmanuel Besnier, Marc‐Olivier Fischer, Sébastien Preau, Fabienne Tamion, Cédric Daubin, Nicolas Cousin, André Vincentelli, Julien Goutay, Damien du Cheyron,
... levels and hemorrhagic events under ECMO using anti-Xa activity monitoring. Methods We performed a retrospective multicenter ... September 2017 and August 2019 were included. Anti-Xa activities were collected until a hemorrhagic event in ... dosages were averaged to obtain means of anti-Xa activity for each patient, and patients were compared ... presented a hemorrhagic complication. In univariate analysis, anti-Xa activities were significantly higher in the bleeding group ... non-bleeding group, both for the mean anti-Xa activity (0.38 [0.29–0.67] vs ...
Tópico(s): Heart Failure Treatment and Management
2021 - BioMed Central | Critical Care
Omar Taleb, Mohammed Maammar, Christian Klein, Michel Maître, Ayikoe Guy Mensah‐Nyagan,
Xanthurenic acid (XA) is a metabolite of the kynurenine pathway (KP) synthetized in the brain from dietary or microbial tryptophan that ... the blood-brain barrier through carrier-mediated transport. XA and kynurenic acid (KYNA) are two structurally related ... and/or neurodegenerative diseases. Particularly, various data including XA cerebral distribution (from 1 µM in olfactory bulbs ... its release, and interactions with G protein-dependent XA-receptor, glutamate transporter and metabotropic receptors, strongly support ...
Tópico(s): Neuroendocrine regulation and behavior
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
... thereby potentiating inactivation of thrombin (factor IIa), factor Xa and factor IXa. Unfractionated heparin given i.v. ... weight heparins (LMWHs) act predominantly to inhibit factor Xa. In addition to venous thromboembolism (VTE) prophylaxis and ... PubMed Scopus (5) Google Scholar Whilst anti-factor Xa can be used to monitor drug concentrations, there ... can be grouped into agents that inhibit factor Xa (fondaparinux and danaparoid) and the thrombin inhibitors (argatroban ... after the last dose and considering anti-factor Xa levels. ASRA's guidance suggests that if a ...
Tópico(s): Spine and Intervertebral Disc Pathology
2021 - Elsevier BV | BJA Education
Pierre Toulon, Motalib Smahi, Neila De Pooter,
... by using the anti-activated factor X (anti-Xa) activity, or the activated partial thromboplastin time (APTT), ... assay. One of the main advantages of anti-Xa relies on its hypothesized standardization, with a unique ... of this study was to compare the anti-Xa-correlated APTT therapeutic ranges calculated using different combinations of APTT (n = 4) and anti-Xa reagents (n = 4) in frozen citrated plasmas from ... the most sensitive reagent, whereas the median anti-Xa activity was between 0.37 IU/ml and ... APTT therapeutic ranges calculated to correlate with anti-Xa activities between 0.30 and 0.70 IU/ ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2021 - Elsevier BV | Journal of Thrombosis and Haemostasis
Julie Farrar, Molly Droege, Carolyn Philpott, Eric Mueller, Neil Ernst, Amy T. Makley, Kaley Deichstetter, Christopher Droege,
Abstract Background Serum anti-factor Xa (anti-Xa) concentration may guide low molecular weight heparin chemoprophylaxis in trauma patients. Higher total body weight (TBW) is a risk factor for subprophylactic anti-Xa and venous thromboembolism (VTE). The purpose of this ... in patients with subprophylactic versus prophylactic trough anti-Xa. Methods This retrospective study included adults admitted to ... trauma service who received enoxaparin chemoprophylaxis, trough anti-Xa assessment, and screening duplex ultrasound. Initial enoxaparin dose ...
Tópico(s): Cardiac Arrest and Resuscitation
2021 - Elsevier BV | Journal of Surgical Research
Tung Phi Nguyen, Xuan Thi Phan, Dai Quang Huynh, Ha Thi Viet Truong, Yen Nguyen Hai Le, Tuan Manh Nguyen, Quan Quoc Minh Du, Thao Phuong Le, Hai Ngoc Truong, Thi Thi Ho, Thao Thi Ngoc Pham,
... by laboratory tests, including ACT, APTT, and anti-Xa level. Method. A single-center retrospective observational study ... tertiary hospital. The correlations between ACT, APTT, anti-Xa, antithrombin, and UFH dose were assessed. Results. 129 ... 37 patients were obtained including ACT, APTT, anti-Xa, antithrombin, and UFH dose measured simultaneously. 102 out ... deficiencies. The correlation coefficient between APTT and anti-Xa; ACT and anti-Xa are 0.72 and 0.33, respectively, p < ... exhibited a significant correlation between APTT and anti-Xa (r = 0.80, p < 0.001 ). ACT, on ...
Tópico(s): Heparin-Induced Thrombocytopenia and Thrombosis
2021 - Hindawi Publishing Corporation | Critical Care Research and Practice
Matthias Kainz, Paul Bsuchner, Peter Schellongowski, Martin Dworschak,
... 114) Google Scholar Andexanet alfa, a recombinant factor Xa without intrinsic activity, was US Food and Drug ... 2018 for the reversal of direct oral factor Xa inhibitors (eg, apixaban and rivaroxaban) by high-affinity ... 350PT (%)456370-125INR1.51.2aPTT (sec)386827-41Anti-Xa LMWH (IU/mL)1.870.34<0.10Fibrinogen ( ... sec)11323430-110INTEM α-angle (°)685444-66Abbreviations: anti-Xa LMWH, anti-factor Xa activity for low–molecular-weight heparin; aPTT, activated ... Open table in a new tab Abbreviations: anti-Xa LMWH, anti-factor Xa activity for low–molecular- ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2020 - Elsevier BV | Journal of Cardiothoracic and Vascular Anesthesia
Michela Cini, Cristina Legnani, Roberto Padrini, Benilde Cosmi, Claudia Dellanoce, Gaetano De Rosa, Rossella Marcucci, Vittorio Pengo, Daniela Poli, Sophie Testa, Gualtiero Palareti,
Abstract Introduction To measure direct factor Xa inhibitor (apixaban, edoxaban, rivaroxaban) concentrations, dedicated chromogenic anti‐Xa assays are recommended as suitable methods to provide rapid drug quantification. Moreover, the ... a reliable quantitative technique. We investigated seven anti‐Xa assays and an HPLC‐UV method for measurement ... tested by HPLC‐UV and the following anti‐Xa assays: Biophen DiXaI and Heparin LRT (Hyphen BioMed), Berichrom and Innovance Heparin (Siemens), STA‐Liquid Anti‐Xa (Stago Diagnostics), Technochrom anti‐Xa (Technoclone), and HemosIL ...
Tópico(s): Acute Myocardial Infarction Research
2020 - Wiley | International Journal of Laboratory Hematology
Eric J. Ley, Carlos V.R. Brown, Ernest E. Moore, Jack Sava, Kimberly A. Peck, David J. Ciesla, Jason L. Sperry, Anne G. Rizzo, Nelson G. Rosen, Karen J. Brasel, Rosemary A. Kozar, Kenji Inaba, Matthew J. Martin,
... based upon weight should be monitored by anti-Xa levels because of the fluctuations in creatinine clearance ... of <30 mg/dL while closely monitoring anti-Xa levels may be possible in the future, but ... daily and considered for dose adjustment by anti-Xa level.4,47 Pregnant Patients Pregnant patients require ... mg of enoxaparin twice daily titrated by anti-Xa levels targeting a peak range of 0.2 ... enoxaparin twice daily is recommended with similar anti-Xa level titration.58–60 Isolated Orthopedic Injuries and ...
Tópico(s): Case Reports on Hematomas
2020 - Lippincott Williams & Wilkins | Journal of Trauma and Acute Care Surgery
Thomas Hendriks, Scott McGregor, Shilpa Rakesh, Julie Ann Robinson, Kwok M. Ho, Ross Baker,
... treatment and secondary prevention of venous thromboembolism. Anti-Xa direct oral anticoagulants are alternatives to warfarin; however ... satisfaction after switching from warfarin to an anti-Xa direct oral anticoagulant in patients for treatment of ... thromboembolism after conversion from warfarin to an anti-Xa direct oral anticoagulant.A retrospective cohort study with ... satisfaction and review of adverse events following anti-Xa direct oral anticoagulant replacement of warfarin for treatment ... survey of patient's relative satisfaction of anti-Xa direct oral anticoagulant therapy compared with previous warfarin ...
Tópico(s): Cardiac Arrhythmias and Treatments
2020 - Public Library of Science | PLoS ONE
Yuhki Yanase, Yoshimi Matsuo, Shunsuke Takahagi, Tomoko Kawaguchi, Kazue Uchida, Kaori Ishii, Akio Tanaka, Daiki Matsubara, Koichiro Ozawa, Michihiro Hide,
... factors with serine protease activity, such as factor Xa and thrombin (IIa), resulting in the gap formation ... agonist) nor the activated extrinsic coagulation factors VIIa, Xa, and IIa nor the fibrinolytic factor plasmin induced ... C5 in the presence of factor VIIa, factor Xa, factor IIa, or plasmin on the degranulation of ... Although neither C5 nor factor VIIa nor factor Xa nor factor IIa induced degranulation of hsMCs by ... degranulation of hsMCs in the presence of factor Xa, factor IIa, or plasmin, suggesting that C5a converted ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2020 - Elsevier BV | Journal of Allergy and Clinical Immunology
Mattia Trunfio, Elena Salvador, Daniela Cabodi, Letizia Marinaro, Chiara Alcantarini, Alberto Gaviraghi, Alice Trentalange, Filippo Lipani, Savino Sciascia, Dario Roccatello, Stefano Bonora, Giovanni Di Perri, Andrea Calcagno,
... target inhibition of the activated factor X (anti-Xa): 95–100% compared to 27% in internal wards [[ ... to heparin resistance and decreased recovery of anti-Xa activity [3White D. MacDonald S. Bull T. et ... hypothesized a better and promising application of anti-Xa assessment in monitoring the downstream heparin activity in ... expensive and not routinely manageable. To support anti-Xa monitoring in routine clinical management of COVID-19 ... timing? Do we have to target higher anti-Xa ranges compared to those validated in surgical and ...
Tópico(s): Heart Rate Variability and Autonomic Control
2020 - Elsevier BV | Thrombosis Research
Elodie Boissier, Thomas Sénage, Antoine Babuty, Isabelle Gouin‐Thibault, Bertrand Rozec, Jean‐Christian Roussel, Marianne Sigaud, Catherine Ternisien, Marc Trossaërt, Marc Fouassier, Karim Lakhal,
... usefulness in perioperative and acute care settings, factor-Xa inhibitor-specific assays are scarcely available, contrary to heparin anti-Xa assay. We assessed whether the heparin anti-Xa assay can (1) be used as a screening ... analysis, we evaluated the ability of heparin anti-Xa assay to detect levels of factor-Xa inhibitors above or below the abovementioned safety thresholds ... test). Among samples with relevant levels of factor-Xa inhibitor, we determined the conversion factor linking the measured level and heparin anti-Xa activity in a derivation cohort. In a validation ...
Tópico(s): Acute Myocardial Infarction Research
2020 - Lippincott Williams & Wilkins | Anesthesia & Analgesia