Cristina Miralles, Àlvar Agustí, Christiane Aubry, Jean-Charles Sánchez, Claude Walzer, Denis F. Hochstrasser, Xavier Busquets,
Molecular oxygen (O 2 ) regulates the expression of a variety of genes. Several of the proteins that respond to changes in oxygen concentration have been identified in a variety of cell lines. We extend these previous studies by analyzing the effect of oxygen on the entire protein expression profile of an intact organ using high‐resolution two‐dimensional gel electrophoresis. To this end, we used an isolated, in vitro perfused organ preparation to produce two groups of rat livers perfused with high ( ...
Tópico(s): Amino Acid Enzymes and Metabolism
2000 - Wiley | European Journal of Biochemistry
Nawal M. Boukli, E. Sunderasan, Alexander V. Bartsev, D Hochstrasser, Xavier Perret, Anthony J. Bjourson, Andréa Krause, W. J. Broughton,
Interactions between legumes and rhizobia are controlled by the sequential exchange of symbiotic signals. Two different techniques, 2D-PAGE electrophoresis and differential display were used to study the effects of rhizobial signals on legume development. Application of variously substituted lipo-oligo-saccharidic Nod-factors to roots of Vigna unguiculata resulted in changes in the phosphorylation patterns of microsomal proteins. Reliable amino-acid sequences were obtained for one Nod-factor enhanced ...
Tópico(s): Agronomic Practices and Intercropping Systems
2006 - Elsevier BV | Journal of Plant Physiology
Natacha Turck, Xavier Robin, Nadia Walter, Catherine Fouda, Alexandre Hainard, Roman Sztajzel, G. Wagner, Denis F. Hochstrasser, Joan Montaner, Pierre R. Burkhard, Jean-Charles Sánchez,
Background Ability to accurately determine time of stroke onset remains challenging. We hypothesized that an early biomarker characterized by a rapid increase in blood after stroke onset may help defining better the time window during which an acute stroke patient may be candidate for intravenous thrombolysis or other intravascular procedures. Methods The blood level of 29 proteins was measured by immunoassays on a prospective cohort of stroke patients (N = 103) and controls (N = 132). Mann-Whitney U ...
Tópico(s): Glutathione Transferases and Polymorphisms
2012 - Public Library of Science | PLoS ONE
Florent Glück, Christine Hoogland, Paola Antinori, Xavier Robin, Frédéric Nikitin, Anne Zufferey, Carla Pasquarello, Vanessa Fétaud, Loı̈c Dayon, Markus Müller, Frédérique Lisacek, Laurent Geiser, Denis F. Hochstrasser, Jean-Charles Sánchez, Alexander Scherl,
High throughput protein identification and quantification analysis based on mass spectrometry are fundamental steps in most proteomics projects. Here, we present EasyProt (available at http://easyprot.unige.ch), a new platform for mass spectrometry data processing, protein identification, quantification and unexpected post-translational modification characterization. EasyProt provides a fully integrated graphical experience to perform a large part of the proteomic data analysis workflow. Our goal ...
Tópico(s): Metabolomics and Mass Spectrometry Studies
2012 - Elsevier BV | Journal of Proteomics
Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H. Abildgaard, Yakubu Princely Abudu, Abraham Acevedo‐Arozena, Iannis E. Adamopoulos, Khosrow Adeli, Timon E. Adolph, Annagrazia Adornetto, Elma Aflaki, Galila Agam, Anupam Agarwal, Bharat B. Aggarwal, Maria Agnello, Patrizia Agostinis, Javed N. Agrewala, Alexander Agrotis, Patricia V. Aguilar, S. Tariq Ahmad, Zubair M. Ahmed, Ulises Ahumada-Castro, Sonja Aits, Shu Aizawa, Yunus Akkoç, Tonia Akoumianaki, Hafize Aysin Akpinar, Ahmed M. Al‐Abd, Lina Al-Akra, Abeer Gharaibeh, Moulay A. Alaoui‐Jamali, Simon Alberti, Elísabet Alcocer‐Gómez, Cristiano Alessandri, Muhammad Ali, Md. Abdul Alim Al‐Bari, Saeb Aliwaini, Javad Alizadeh, Eugènia Almacellas, Alexandru Almasan, Alicia Alonso, G. Alonso, Nihal Altan‐Bonnet, Dario C. Altieri, Élida Álvarez, Sara Alves, Cristine Alvès da Costa, Mazen M. Alzaharna, Marialaura Amadio, Consuelo Amantini, Cristina Amaral, Susanna Ambrosio, Amal O. Amer, Veena Ammanathan, Zhenyi An, Stig Uggerhøj Andersen, Shaida A. Andrabi, Magaiver Andrade-Silva, Allen M. Andres, Sabrina Angelini, David K. Ann, Uche C. Anozie, Mohammad Y. Ansari, Pedro Antas, Adam Antebi, Zuriñe Antón, Tahira Anwar, Lionel Apétoh, Nadezda Apostolova, Toshiyuki Araki, Yasuhiro Araki, Kohei Arasaki, Wagner L. Araújo, Jun Araya, Catherine Arden, María‐Ángeles Arévalo, Sandro Argüelles, Esperanza Arias, Jyothi Arikkath, Hirokazu Arimoto, Aileen Ariosa, Darius Armstrong‐James, Laetitia Pelloquin, Ángeles Aroca, Daniela S. Arroyo, Ivica Arsov, Rubén Artero, Dalia Maria Lucia Asaro, Michael Aschner, Milad Ashrafizadeh, Osnat Ashur‐Fabian, Atanas G. Atanasov, Alicia K. Au, Patrick Auberger, Holger W. Auner, Laure Aurelian, Riccardo Autelli, Laura Avagliano, Yenniffer Ávalos, Sanja Aveic, Célia A. Aveleira, Tamar Avin‐Wittenberg, Yücel Aydın, Scott Ayton, Srinivas Ayyadevara, Maria Azzopardi, Misuzu Baba, Jonathan Backer, Steven K. Backues, Dong-Hun Bae, Ok‐Nam Bae, Soo Han Bae, Eric H. Baehrecke, Ahruem Baek, Seung‐Hoon Baek, Sung Hee Baek, Giacinto Bagetta, Agnieszka Bagniewska‐Zadworna, Hua Bai, Jie Bai, Xiyuan Bai, Yidong Bai, Nandadulal Bairagi, Shounak Baksi, Teresa Balbi, Cosima T. Baldari, Walter Balduini, Andrea Ballabio, María Ballester, Salma Balazadeh, Rena Balzan, Rina Bandopadhyay, Sreeparna Banerjee, Sulagna Banerjee, Ágnes Bánréti, Yan Bao, Maurı́cio S. Baptista, Alessandra Baracca, Cristiana Barbati, Ariadna Bargiela, Daniela Barilà, Peter G. Barlow, Sami J. Barmada, Esther Barreiro, George E. Barreto, Jiří Bártek, Bonnie Bartel, Alberto Bartolomé, Gaurav Barve, Suresh H. Basagoudanavar, Diane C. Bassham, Robert C. Bast, Alakananda Basu, Henri Batoko, Isabella Batten, E.E. Baulieu, Bradley L. Baumgarner, Jagadeesh Bayry, Rupert Beale, Isabelle Beau, Florian Beaumatin, Luiz R. G. Bechara, George R. Beck, Michael F. Beers, Jakob Begun, Christian Behrends, Georg M. N. Behrens, Roberto Bei, Eloy Bejarano, Shai Bel, Christian Behl, Amine Belaïd, Naïma Belgareh‐Touzé, Cristina Bellarosa, Francesca Belleudi, Melissa Belló-Pérez, Raquel Bello-Morales, Jackeline Soares de Oliveira Beltran, Sebastián Beltran, Doris M. Benbrook, Mykolas Bendorius, Bruno A. Benítez, Irene Benito‐Cuesta, Julien Bensalem, Martin W. Berchtold, Sabina Berezowska, Daniele Bergamaschi, Matteo Bergami, Andreas Bergmann, Laura Berliocchi, Clarisse Berlioz‐Torrent, Amélie Bernard, Lionel Berthoux, Cagri G. Besirli, Sébastien Besteiro, Virginie M.S. Betin, Rudi Beyaert, Jelena S. Bezbradica, Kiran Bhaskar, Ingrid Bhatia‐Kiššová, Resham Bhattacharya, Sujoy Bhattacharya, Shalmoli Bhattacharyya, Md. Shenuarin Bhuiyan, Sujit K. Bhutia, Lanrong Bi, Xiaolin Bi, Trevor J. Biden, Krikor Bijian, Viktor Billes, Nadine Binart, Cláudia Bincoletto, Åsa Birna Birgisdottir, Geir Bjørkøy, Gonzalo Blanco, Ana Blas‐García, Janusz Błasiak, Robert Blomgran, Klas Blomgren, Janice S. Blum, Emilio Boada-Romero, Mirta Boban, Kathleen Boesze‐Battaglia, Philippe Boeuf, Barry Boland, Pascale Bomont, Paolo Bonaldo, Srinivasa Reddy Bonam, Laura Bonfili, Juan S. Bonifacino, Brian A. Boone, Martin D. Bootman, Matteo Bordi, Christoph Borner, Beat Bornhäuser, Gautam Borthakur, Jürgen Bosch, Santanu Bose, Luís M. Botana, Juan Botas, Chantal M. Boulanger, Michael E. Boulton, Mathieu Bourdenx, Benjamin Bourgeois, Nollaig M. Bourke, Guilhem Bousquet, Patricia Boya, Peter V. Bozhkov, Luiz H. M. Bozi, Tolga O. Bozkurt, Doug E. Brackney, Christian Brandts, Ralf J. Braun, Gerhard H. Braus, Roberto Bravo, José Manuel Bravo‐San Pedro, Patrick Brest, Marie-Agnès Bringer, Alfredo Briones‐Herrera, V. Courtney Broaddus, Peter Brodersen, Jeffrey L. Brodsky, Steven L. Brody, Paola G. Bronson, Jeff M. Bronstein, Carolyn N. Brown, Rhoderick E. Brown, Patrı́cia C. Brum, John H. Brumell, Nicola Brunetti‐Pierri, Daniele Bruno, Robert J. Bryson‐Richardson, Cecilia Bucci, Carmen Buchrieser, Marta Bueno, Laura Elisa Buitrago‐Molina, Simone Buraschi, Shilpa Buch, J. Ross Buchan, Erin M. Buckingham, Hikmet Budak, Mauricio Budini, Geert Bultynck, Florin Burada, Joseph R. Burgoyne, María I. Burón, Victor Bustos, Sabrina Büttner, Elena Butturini, Aaron Byrd, Isabel Cabas, Sandra Cabrera,
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, ...
Taylor & Francis
Noboru Mizushima, Hisao Sugita, Tamotsu Yoshimori, Yoshinori Ohsumi,
... that end with Gly-Gly (40Johnson P.R. Hochstrasser M. Trends Cell Biol. 1997; 7: 408-413Abstract ...
Tópico(s): Cancer-related gene regulation
1998 - Elsevier BV | Journal of Biological Chemistry
Anne‐Paule Gimenez‐Roqueplo, Jérôme Célérier, G. Lucarelli, Pierre Corvol, Xavier Jeunemaı̂tre,
... mammalian species (9Skeggs L.T. Lentz K.E. Hochstrasser H. Kahn J.R. J. Exp. Med. 1963; ...
Tópico(s): Cardiovascular, Neuropeptides, and Oxidative Stress Research
1998 - Elsevier BV | Journal of Biological Chemistry
A Minty, Xavier Dumont, Mourad Kaghad, Daniel Caput,
... SUMO-1-cleaving protease Ulp1 (17Li S.-J. Hochstrasser M. Nature. 1999; 398: 246-251Crossref PubMed Scopus ( ...
Tópico(s): Ubiquitin and proteasome pathways
2000 - Elsevier BV | Journal of Biological Chemistry
Robert Liddington, Christin Frederick, Jane Clarke, Sophie Jackson,
... Tang, J., Jia, Y., DeGrado, W. F., and Hochstrasser, R. M. (2000). Proc. Natl. Acad. Sci. USA ...
Tópico(s): Cell death mechanisms and regulation
2001 - Elsevier BV | Structure