Bin Xue, Jiaqi Xu, Wenru Song, Zhimin Yang, Ke Liu, Zihai Li, Zihai Li, Lieping Chen, Edward B. Garon, Siwen Hu‐Lieskovan, Wei Ding, Chong-xian Pan, Weijing Sun, Yongjun Liu, Lei Zheng, Delong Liu, Michel Sadelain, Cassian Yee, Rong‐Fu Wang, Meixia Chen, Yao Wang, Zhiqiang Wu, Hanren Dai, Can Luo, Yang Liu, Chuan Tong, Yelei Guo, Qingming Yang, Weidong Han, Lisa H. Butterfield, Timothy A. Chan, Wenru Song, RuiRong Yuan, Bo Lü, Ke Liu, Max Ning, Harald Enzmann, H. Zwierzina,
... China Cancer Immunotherapy Workshop, Beijing, China Bin Xue, Jiaqi Xu, Wenru Song, Zhimin Yang, Ke Liu, Zihai Li ...
Tópico(s): Immunotherapy and Immune Responses
2016 - BioMed Central | Journal of Hematology & Oncology
Yuanqing Wang, Jinghao Zhang, Yongchao Zheng, Yangrui Xu, Jiaqi Xu, Jiao Jiao, Yun Su, Hai‐Feng Lü, Kun Liang,
The Brillouin scattering spectrum has been used to investigate the properties of a liquid medium. Here, we propose an improved method based on the double-edge technique to obtain the Brillouin spectrum of a liquid. We calculated the transmission ratios and deduced the Brillouin shift and linewidth to construct the Brillouin spectrum by extracting the Brillouin edge signal through filtered double-edge data. We built a detection system to test the performance of this method and measured the Brillouin ...
Tópico(s): Photoacoustic and Ultrasonic Imaging
2022 - | Opto-Electronic Advances
Bozhao Li, Tianjiao Chu, Jingyan Wei, Yinlong Zhang, Feilong Qi, Zefang Lu, Chao Gao, Tianjiao Zhang, Ershuai Jiang, Junchao Xu, Jiaqi Xu, Suping Li, Guangjun Nie,
Compared with traditional chemotherapeutics, vascular disruption agents (VDAs) have the advantages of rapidly blocking the supply of nutrients and starving tumors to death. Although the VDAs are effective under certain scenarios, this treatment triggers angiogenesis in the later stage of therapy that frequently leads to tumor recurrence and treatment failure. Additionally, the nonspecific tumor targeting and considerable side effects also impede the clinical applications of VDAs. Here we develop ...
Tópico(s): Extracellular vesicles in disease
2021 - American Chemical Society | Nano Letters
Yao Li, Ruifang Zhao, Keman Cheng, Kaiyue Zhang, Shaobin Wang, Yinlong Zhang, Yujing Li, Guangna Liu, Junchao Xu, Jiaqi Xu, Gregory J. Anderson, Jian Shi, Lei Ren, Xiao Zhao, Guangjun Nie,
Natural, extracellular membrane vesicles secreted by Gram-negative bacteria, outer membrane vesicles (OMVs), contain numerous pathogen-associated molecular patterns which can activate systemic immune responses. Previous studies have shown that OMVs induce strong IFN-γ- and T cell-mediated anti-tumor effects in mice. However, IFN-γ is known to upregulate immunosuppressive factors in the tumor microenvironment, especially the immune checkpoint programmed death 1 ligand 1 (PD-L1), which may hamper T ...
Tópico(s): Extracellular vesicles in disease
2020 - American Chemical Society | ACS Nano
Guangna Liu, Xiao Zhao, Yinlong Zhang, Junchao Xu, Jiaqi Xu, Yao Li, Huan Min, Jian Shi, Ying Zhao, Jingyan Wei, Jing Wang, Guangjun Nie,
Biomimetic camouflage, i.e., using natural cell membranes for drug delivery, has demonstrated advantages over synthetic materials in both pharmacokinetics and biocompatibility, and so represents a promising solution for the development of safe nanomedicine. However, only limited efforts have been dedicated to engineering such camouflage to endow it with optimized or additional properties, in particular properties critical to a "smart" drug delivery system, such as stimuli-responsive drug release. ...
Tópico(s): Dendrimers and Hyperbranched Polymers
2019 - | Advanced Materials
Wen-Mei Xu, Jiaqi Xu, Yao Zhou, Yang Li, Zhenzhen Lu, Jing Hou, Lin Zhu, Heng‐Lin Cui,
Tópico(s): Coral and Marine Ecosystems Studies
2016 - Springer Science+Business Media | Antonie van Leeuwenhoek
Hongkun Xue, Jiaqi Xu, Jinling Zhang, Yaning Wei, Xu Cai, Jiaqi Tan,
Ultrasound assisted aqueous two-phase extraction of polysaccharides from Lilium lancifolium Thunb was modeled by response surface methodology (RSM) and artificial neural network (ANN), and optimized using genetic algorithm coupled with ANN (GA-ANN). Statistical analysis showed that the models obtained by RSM and ANN could accurately predict the Lilium lancifolium Thunb polysaccharides (LLPs) yield. However, ANN prediction was more accurate than RSM. The optimum extraction parameters to achieve the highest ...
Tópico(s): Phytochemical Studies and Bioactivities
2022 - Elsevier BV | LWT
Xiaoning Zhao, Zeying Fan, Haiyang Xu, Zhongqiang Wang, Jiaqi Xu, Jiangang Ma, Yichun Liu,
A new operating scheme for voltage-polarity-controlled multilevel memory based on Ag/MoS 2 /Au flexible structure with reversible alternation between bipolar and unipolar resistive switching modes was demonstrated.
Tópico(s): Perovskite Materials and Applications
2018 - Royal Society of Chemistry | Journal of Materials Chemistry C
Liangliang Zhang, Jiasheng Xu, Haiying Shen, Jiaqi Xu, Jinzhen Cao,
Flammability, as an undesirable inherent nature of wood, limits its usage in many fields of structural applications. Hybrid organic-inorganic modification offers a way to improve the flame retardancy of wood. In this study, montmorillonite (MMT)-catalyzed furfurylated wood was prepared by polymerization of furfuryl alcohol (FA) with hydrogen-MMT (H-MMT) used as catalyst. Poplar wood (Populus cathayana Rehd.) was delignified at first to increase its nanoporosity, and then impregnated with H-MMT/FA suspensions, ...
Tópico(s): Natural Fiber Reinforced Composites
2021 - Elsevier BV | Fire Safety Journal
Xiaolong Sheng, Jinyun Zhao, Miao Li, Yan Xu, Yi Zhou, Jiaqi Xu, Rundong He, Hongbin Lü, Tianding Wu, Chunyue Duan, Yong Cao, Jianzhong Hu,
Macrophage phagocytosis contributes predominantly to processing central nervous system (CNS) debris and further facilitates neurological function restoration after CNS injury. The aims of this study were to evaluate the effect of bone marrow mesenchymal stem cells (BMSC)-derived exosomes (BMSC-Exos) on the phagocytic capability of macrophages to clear myelin debris and to investigate the underlying molecular mechanism during the spinal cord injury (SCI) process. This work reveals that monocyte-derived ...
Tópico(s): Spinal Dysraphism and Malformations
2021 - Frontiers Media | Frontiers in Cell and Developmental Biology
Xiaoning Zhao, Zhongqiang Wang, Wentong Li, Shaowu Sun, Haiyang Xu, Peng Zhou, Jiaqi Xu, Ya Lin, Yichun Liu,
In article number 1910151, Haiyang Xu, Peng Zhou, Yichun Liu, and co-workers propose a photo-assisted electroforming strategy in organic–inorganic hybrid perovskite memristors. The mild method can effectively suppress the undesirable current overshoot and enable reliable low power CH3NH3PbI3-based memristors. The proposed strategy provides a simple and effective way to optimize the performance of memristors based on light-sensitive materials.
Tópico(s): Polydiacetylene-based materials and applications
2020 - Wiley | Advanced Functional Materials
Xiaoning Zhao, Zhongqiang Wang, Wentong Li, Shaowu Sun, Haiyang Xu, Peng Zhou, Jiaqi Xu, Ya Lin, Yichun Liu,
Abstract Organic–inorganic hybrid perovskite memristors with high resistive‐switching (RS) reliability and low power consumption are crucial for high‐density storage and high‐efficiency neuromorphic computing. However, the current overshoot in the electroforming process generally induces overgrowth of conductive filaments (CFs) and degrades the RS performance. Here, a simple photo‐assisted electroforming (PAE) method to suppress the current overshoot, in which the visible light irradiation is introduced ...
Tópico(s): Conducting polymers and applications
2020 - Wiley | Advanced Functional Materials
Junchao Xu, Yinlong Zhang, Jiaqi Xu, Guangna Liu, Chunzhi Di, Xiao Zhao, Xiang Li, Yao Li, Ningbo Pang, Chengzhi Yang, Yanyi Li, Bozhao Li, Zefang Lu, Meifang Wang, Kesheng Dai, Rong Yan, Suping Li, Guangjun Nie,
Rapid cut-off of blood supply in diseases involving thrombosis is a major cause of morbidity and mortality worldwide. However, the current thrombolysis strategies offer limited results due to the therapeutics' short half-lives, low targeting ability, and unexpected bleeding complications. Inspired by the innate roles of platelets in hemostasis and pathological thrombus, platelet membrane-camouflaged polymeric nanoparticles (nanoplatelets) are developed for targeting delivery of the thrombolytic drug, ...
Tópico(s): Blood properties and coagulation
2019 - | Advanced Materials
Xiaohong Guo, Tingting Li, Yang Xu, Xiayan Xu, Zhengyi Zhu, Yun Zhang, Jiaqi Xu, Kaihong Xu, Hongqiang Cheng, Xue Zhang, Yuehai Ke,
M2-polarized macrophages, also known as alternatively activated macrophages, have long been associated with pulmonary fibrosis; however, the mechanism has not been fully defined. Gab1 and Gab2 proteins belong to the Gab family of adaptors and are integral components of the signal specificity in response to various extracellular stimuli. In this report, we found that levels of both Gab1 and Gab2 were elevated in M2-polarized macrophages isolated from bleomycin-induced fibrotic lungs. In vitro Gab1/ ...
Tópico(s): Studies on Chitinases and Chitosanases
2017 - Elsevier BV | Journal of Biological Chemistry
Yun Zhang, Yang Xu, Shuwan Liu, Xiaohong Guo, Dong Cen, Jiaqi Xu, Heyuan Li, Kaijun Li, Chunlai Zeng, Linrong Lu, Yiting Zhou, Huahao Shen, Hongqiang Cheng, Xue Zhang, Yuehai Ke,
Asthma is a common allergic disorder involving a complex interplay among multiple genetic and environmental factors. Recent studies identified genetic variants of human GAB1 as a novel asthma susceptibility factor. However, the functions of Gab1 in lung remain largely unexplored. In this study, we first observed an elevation of Gab1 level in peripheral blood mononuclear cells from asthmatic patients during acute exacerbation compared with convalescence. Mice with a selectively disrupted Gab1 in ...
Tópico(s): Cell Adhesion Molecules Research
2016 - Springer Nature | Cell Research
Jiaqi Xu, Gastón A. Fermandois, Billie F. Spencer, Xilin Lü,
A stochastic optimisation procedure is proposed for the design of low- and mid-rise buckling restrained braced frames subject to seismic loading. The seismic excitation is represented as a zero-mean nonstationary filtered white noise. The Bouc–Wen model is chosen to represent the hysteretic behaviour of the buckling restrained braces. The equivalent linearisation method is employed to determine the second-order statistics of structural responses from the non-linear system. Three seismic intensity ...
Tópico(s): Structural Health Monitoring Techniques
2018 - Taylor & Francis | Structure and Infrastructure Engineering
Jiaqi Xu, Pengfei Wang, Haoming Pang, Yunpeng Wang, Jie Wu, Shouhu Xuan, Xinglong Gong,
The dynamic mechanical properties of magnetorheological plastomers (MRPs) were investigated by using a Split Hopkinson Pressure Bar (SHPB) equipped with an electromagnetic accessory. Both the SHPB and rheological test indicated the mechanical properties of MRPs increased with strain rate, which demonstrated the typical rate dependent stiffening performance. With strain rate increased from 1580 s−1 to 7900 s−1, the maximum stress of MRPs increased from 31 MPa to 66 MPa. MRPs also exhibited a magnetic ...
Tópico(s): Elasticity and Material Modeling
2018 - Elsevier BV | Composites Science and Technology
Haiying Shen, Jinzhen Cao, Jun Jiang, Jiaqi Xu,
The weathering of thermally treated wood by light radiation and water is an important problem for the wood used in outdoor applications. In this study, a durable hydrophobic and UV-resistant layer was successfully formed on the surface of thermally treated wood at room temperature after in situ deposition of titanium dioxide (TiO2) nanoparticles and a polydimethysiloxane (PDMS) coating. The morphology of the rutile TiO2 nanoparticles formed on wood surface, varying from spherical (A-TiO2) to acicular ( ...
Tópico(s): Building materials and conservation
2018 - Elsevier BV | Progress in Organic Coatings
Jiaqi Xu, Yanyu Lu, Guangchun Shan, Xiaosong He, Junhao Huang, Qunliang Li,
Tópico(s): Constructed Wetlands for Wastewater Treatment
2018 - Springer Science+Business Media | Waste and Biomass Valorization
Jun He, Yage Guo, Jiaqi Xu, Hao Li, Anna Fuller, Richard G. Tait, Xiao‐Lin Wu, Stewart Bauck,
SNPs are informative to estimate genomic breed composition (GBC) of individual animals, but selected SNPs for this purpose were not made available in the commercial bovine SNP chips prior to the present study. The primary objective of the present study was to select five common SNP panels for estimating GBC of individual animals initially involving 10 cattle breeds (two dairy breeds and eight beef breeds). The performance of the five common SNP panels was evaluated based on admixture model and linear ...
Tópico(s): Meat and Animal Product Quality
2018 - BioMed Central | BMC Genomic Data
Jiaqi Xu, Xiaoning Zhao, Zhongqiang Wang, Haiyang Xu, Junli Hu, Jiangang Ma, Yichun Liu,
Abstract Transient electronics that can physically vanish in solution can offer opportunities to address the ecological challenges for dealing with the rapidly growing electronic waste. As one important component, it is desirable that memory devices combined with the transient feature can also be developed as secrecy information storage systems besides the above advantage. Resistive switching (RS) memory is one of the most promising technologies for next‐generation memory. Herein, the biocompatible ...
Tópico(s): Ferroelectric and Negative Capacitance Devices
2018 - Wiley | Small
As an effective alternative to manual operation of hydraulic excavators, automated systems are being developed for common tasks that excavators routinely perform on typical job sites. An example is an automated ground grading system that can enhance the productivity of excavators by assisting the operator to perform ground grading in a fast and accurate manner. To develop an automated grading system, sensors are needed to measure the position of the hydraulic manipulator linkages for the feedback ...
Tópico(s): Infrastructure Maintenance and Monitoring
2018 - Elsevier BV | Automation in Construction
Jiaqi Xu, Xiaodong Li, Zhengyu Ju, Yongfu Sun, Xingchen Jiao, Ju Wu, Chengming Wang, Wensheng Yan, Huanxin Ju, Junfa Zhu, Yi Xie,
Abstract Directly splitting water into H 2 and O 2 with solar light is extremely important; however, the overall efficiency of water splitting still remains extremely low. Two types of ultrathin semiconductor layers with the same elements and the same thicknesses were designed to uncover how different atomic arrangements influence water‐splitting efficiency thermodynamically and kinetically. As an example, tetrahedrally coordinated blende and octahedrally coordinated rocksalt CoO atomic layers with ...
Tópico(s): ZnO doping and properties
2018 - Wiley | Angewandte Chemie
Jiaqi Xu, Xiaodong Li, Zhengyu Ju, Yongfu Sun, Xingchen Jiao, Ju Wu, Chengming Wang, Wensheng Yan, Huanxin Ju, Junfa Zhu, Yi Xie,
Directly splitting water into H2 and O2 with solar light is extremely important; however, the overall efficiency of water splitting still remains extremely low. Two types of ultrathin semiconductor layers with the same elements and the same thicknesses were designed to uncover how different atomic arrangements influence water-splitting efficiency thermodynamically and kinetically. As an example, tetrahedrally coordinated blende and octahedrally coordinated rocksalt CoO atomic layers with nearly ...
Tópico(s): Electronic and Structural Properties of Oxides
2018 - Wiley | Angewandte Chemie International Edition
Ju Wu, Xiaodong Li, Wen Shi, Peiquan Ling, Yongfu Sun, Xingchen Jiao, Shan Gao, Liang Liang, Jiaqi Xu, Wensheng Yan, Chengming Wang, Yi Xie,
Solar CO2 reduction efficiency is largely limited by poor photoabsorption, sluggish electron-hole separation, and a high CO2 activation barrier. Defect engineering was employed to optimize these crucial processes. As a prototype, BiOBr atomic layers were fabricated and abundant oxygen vacancies were deliberately created on their surfaces. X-ray absorption near-edge structure and electron paramagnetic resonance spectra confirm the formation of oxygen vacancies. Theoretical calculations reveal the ...
Tópico(s): Advanced Photocatalysis Techniques
2018 - Wiley | Angewandte Chemie International Edition
Xiaodong Li, Liang Liang, Yongfu Sun, Jiaqi Xu, Xingchen Jiao, Xiaoliang Xu, Huanxin Ju, Yang Pan, Junfa Zhu, Yi Xie,
The concurrent transformation of carbon dioxide and water into hydrocarbons and oxygen by low-photonic-energy IR light still represents a huge challenge. Here, we design an ultrathin conductor system, in which the special partially occupied band serves as the mediator to simultaneously guarantee IR light harvesting and satisfy band-edge positions, while the ultrathin configuration improves charge separation rates and surface redox kinetics. Taking the low cost and earth-abundant CuS as an example, ...
Tópico(s): ZnO doping and properties
2018 - American Chemical Society | Journal of the American Chemical Society
Shiyu Ma, Ying Wang, Jiaqi Xu, Lin Zheng,
Cupping therapy has been widely used in Eastern Asia, the Middle East, or Central and North Europe to manage the symptom of ankylosing spondylitis (AS). The aim of this systematic review was to review data from randomized controlled trials (RCTs) of cupping therapy for treating patients with AS.Databases that were searched from their inception until December 2017 included: MEDLINE, CINAHL, EMBASE, AMED, Cochrane Central Register of Controlled Trials, four Chinese databases [Chinese BioMedical Database, ...
Tópico(s): Fibromyalgia and Chronic Fatigue Syndrome Research
2018 - Elsevier BV | Complementary Therapies in Clinical Practice
Wei Liu, Jiaqi Xu, Junwei Han, Fen Jiao, Wenqing Qin, Zhuzhang Li,
The kinetic and mechanism of pyrolysis for Cu-free printed circuit board (CFPCB) and Cu-coated printed circuit board (CCPCB) were studied using nonisothermal thermo-gravimetry (TG) analysis coupled with Fourier-transform infrared (FTIR) spectrometry. TG and DTG (differential thermo-gravimetry) analyses were performed to study the mass loss characteristics. Kinetic analysis adopted the Ozawa–Flynn–Wall (OFW) model to confirm the reaction series by the variation pattern of activation energy. The real-time ...
Tópico(s): Microplastics and Plastic Pollution
2018 - American Chemical Society | ACS Sustainable Chemistry & Engineering
Nianxiang Qiu, Xiaojing Bai, Jiaqi Xu, Ningru Sun, Joseph S. Francisco, Minghui Yang, Qing Huang, Shiyu Du,
In order to understand the role for different components of flue gases in the replacement of CH4 from natural gas hydrates, in this work, the cage occupancies of SO2, H2S, N2O, NO, and CS2 gases in the structure I (sI) and structure II (sII) hydrates have been investigated by grand canonical Monte Carlo + molecular dynamics simulations. The results show that SO2 and N2O molecules prefer to occupy the large cages (LCs) of sI and sII hydrates, and H2S and NO molecules almost have no preference to cage ...
Tópico(s): CO2 Sequestration and Geologic Interactions
2018 - American Chemical Society | The Journal of Physical Chemistry C
Ju Wu, Xiaodong Li, Wen Shi, Peiquan Ling, Yongfu Sun, Xingchen Jiao, Shan Gao, Liang Liang, Jiaqi Xu, Wensheng Yan, Chengming Wang, Yi Xie,
Abstract Solar CO 2 reduction efficiency is largely limited by poor photoabsorption, sluggish electron–hole separation, and a high CO 2 activation barrier. Defect engineering was employed to optimize these crucial processes. As a prototype, BiOBr atomic layers were fabricated and abundant oxygen vacancies were deliberately created on their surfaces. X‐ray absorption near‐edge structure and electron paramagnetic resonance spectra confirm the formation of oxygen vacancies. Theoretical calculations ...
Tópico(s): CO2 Reduction Techniques and Catalysts
2018 - Wiley | Angewandte Chemie