Sayuri Suwa, Mayuko Tsujimura, Naonori Kodate, Sarah Donnelly, Helli Kitinoja, Jaakko Hallila, Marika Toivonen, Hiroo Ide, Camilla Bergman-Kärpijoki, Erika Takahashi, Mina Ishimaru, Atsuko Shimamura, Wenwei Yu,
To clarify potential users’ perceptions toward the development and social implementation of home-care robots in Japan, Ireland, and Finland. Unsigned, self-administered questionnaires were distributed to adults aged 65 or older, family caregivers, and home-care/health and social care professionals (HSCPs). A total of 1004 responses were collected. In Japan, many people were already familiar with robots in their daily lives. The most notable finding about their perspectives on home-care robots was ...
Tópico(s): AI in Service Interactions
2020 - Elsevier BV | Archives of Gerontology and Geriatrics
Sayuri Suwa, Mayuko Tsujimura, Hiroo Ide, Naonori Kodate, Mina Ishimaru, Atsuko Shimamura, Wenwei Yu,
Because of the workforce shortage in Japan, the use of home-care robots, or carebots, is increasingly perceived as a realistic option. Developing and implementing these carebots requires careful consideration of the ethical implications for all types of users. Few studies, however, have addressed the ethical principles and concepts involved in carebot use, and consequently, the discussion regarding roboethics in the home-care environment has been inadequate. This questionnaire study explored the ...
Tópico(s): Organ Donation and Transplantation
2020 - Taylor & Francis | International Journal of Human-Computer Interaction
Valery I. Chani, Kiyoshi Shimamura, Young Moon Yu, Tsuguo Fukuda,
We introduce a method of searching for crystals with high structural stability and its application to the garnet, KTiOPO4 (KTP), huntite-borate, and langasite structures. Results are presented which show that, by using appropriate substitution, an increase of the stability can be achieved. This review gives models and experimental techniques of optimization of compositions for the complex oxide materials with the given structure. Sometimes application of the method mentioned can be used for the determination ...
Tópico(s): Luminescence Properties of Advanced Materials
1997 - Elsevier BV | Materials Science and Engineering R Reports
Eihaku Shimamura, Ken‐ichi Kasuya, Genta Kobayashi, Takeshi Shiotani, Yu Shima, Yoshiharu Doi,
... Microbial Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)Eihaku Shimamura, Kenichi Kasuya, Genta Kobayashi, Takeshi Shiotani, Yu Shima, and Yoshiharu DoiCite this: Macromolecules 1994, 27, ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
1994 - American Chemical Society | Macromolecules
Mitsuru Kondo, Mariko Shimamura, Shin‐ichiro Noro, Yu Kimura, Kazuhiro Uemura, Susumu Kitagawa,
Two new coordination compounds, [Mn(bpe)2(NCS)2] (bpe, 4,4′-bipyridylethane) (1) and [Cd(dpds)2(H2O)2]·2NO3·2EtOH·2H2O (dpds, 4,4′-dipyridyldisulfide) (2·2EtOH·2H2O), were synthesized and structurally characterized. 1 crystallizes in the monoclinic space group C2/c (No.15) with a=19.928(3) Å, b=10.060(3) Å, c=14.680(3), β=110.30(1)°, V=2760.1(9) Å3, and Z=4.2·2EtOH·2H2O crystallizes in the monoclinic space group P21/n (No. 14) with a=8.9735(9), b=19.835(1), c=10.778(2), β=112.29(1)°, V=1775.1(1) Å3, and ...
Tópico(s): Metal complexes synthesis and properties
2000 - Elsevier BV | Journal of Solid State Chemistry
Tomoyuki Fujii, Keiichiro TOHGO, Naohiro Ishizuka, Yoshinobu SHIMAMURA, Masahiro Takanashi, Yu Itabashi, Gen Nakayama, Yohei Sakakibara, Takashi Hirano,
This paper deals with applicability of non-linear fracture mechanics to crack growth by stress corrosion cracking (SCC) under large-scale yielding and in a plastically deformed area. Crack growth test by compact tension specimen is carried out to evaluate crack growth rate under small-scale and large-scale yielding conditions. To evaluate the crack growth behavior from a crack initiated in a plastically deformed area, crack growth test is also carried out for a very short pre-crack in a plastically ...
Tópico(s): Non-Destructive Testing Techniques
2013 - Japan Society Mechanical Engineers | Journal of Solid Mechanics and Materials Engineering
Toshiaki Imai, Toshishige Fujii, Katsuji Tanemoto, Taisuke Shimamura, Tatsuo Maeda, Hiroaki Ishida, Yu HIBINO,
Since there have been some railway accidents caused by strong winds in recent years in Japan, it is necessary to establish effective measures to prevent wind-induced accidents and ensure safety of train operation under strong winds. On February 22, 1994, a derailment accident was caused by strong winds on the Nemuro line of Hokkaido Railway Company. Railway Technical Research Institute carried out researches on investigation of the accident and measures at this section. As countermeasures, wind ...
Tópico(s): Aerodynamics and Fluid Dynamics Research
2002 - Elsevier BV | Journal of Wind Engineering and Industrial Aerodynamics
Keiichiro TOHGO, Yu Itoh, Yoshinobu SHIMAMURA,
This paper deals with a constitutive model of particulate-reinforced composites which can describe the evolution of debonding damage, matrix plasticity and particle size effects on deformation and damage. An incremental damage model of particulate-reinforced composites based on the Mori–Tanaka's mean field concept has been extended to consider the particle size effects by using the Nan–Clarke's simple method. The particle size effect on deformation is realized by introducing dislocation plasticity ...
Tópico(s): Aluminum Alloys Composites Properties
2009 - Elsevier BV | Composites Part A Applied Science and Manufacturing
Saburo Kawai, Jun Okamura, Makoto Ogawa, Yasuo Ohashi, Masayoshi Tani, J. Inoue, Yoshifumi Kawarada, Mitsuo Kusano, Yasuhiko Kubo, C Kuroda, Yu Sakata, Y Shimamura, Kenji Jinno, Akira Takahashi, Kenichi Takayasu, Kazuo Tamura, Naofumi Nagasue, Yoshimi Nakanishi, M Makino, Manabu Masuzawa, S Mikuriya, Morito Monden, Yasuhiro Yumoto, Takesada Mori, Toshitsugu Oda,
Tópico(s): Lymphoma Diagnosis and Treatment
1992 - Springer Science+Business Media | Cancer Chemotherapy and Pharmacology
Jun Okamura, Saburo Kawai, Makoto Ogawa, Yasuo Ohashi, Masayoshi Tani, J. Inoue, Yoshifumi Kawarada, Mitsuo Kusano, Yasuhiko Kubo, C Kuroda, Yu Sakata, Y Shimamura, Kenji Jinno, Akira Takahashi, Kenichi Takayasu, Kazuo Tamura, Naofumi Nagasue, Yoshimi Nakanishi, M Makino, Manabu Masuzawa, S Mikuriya, Morito Monden, Yasuhiro Yumoto, Takesada Mori, Toshitsugu Oda,
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
1992 - Springer Science+Business Media | Cancer Chemotherapy and Pharmacology
Saburo Kawai, Masayoshi Tani, Jun Okamura, Makoto Ogawa, Yasuo Ohashi, Morito Monden, Shigeki Hayashi, J. Inoue, Yoshifumi Kawarada, Mitsuo Kusano, Yasuhiko Kubo, C Kuroda, Yu Sakata, Y Shimamura, Kenji Jinno, Akira Takahashi, Kenichi Takayasu, Kazuo Tamura, Naofumi Nagasue, Yoshimi Nakanishi, M Makino, Manabu Masuzawa, Yasuhiro Yumoto, Takesada Mori, Toshitsugu Oda,
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
1994 - Springer Science+Business Media | Cancer Chemotherapy and Pharmacology
Hiroo Ide, Naonori Kodate, Sayuri Suwa, Mayuko Tsujimura, Atsuko Shimamura, Mina Ishimaru, Wenwei Yu,
Japan is facing a ‘care crisis’. There is an urgent need to ascertain the extent to which potential users are willing to use robotics-aided care before its roll-out as a formal policy. Based on our recent survey, we discuss home-care professionals’ real perceptions and their implications for the future development and implementation of home-care robots. While they showed some concerns about robotics-aided care, they perceived ‘physical support’, ‘communication’ and ‘monitoring’ functions positively. ...
Tópico(s): Technology Use by Older Adults
2021 - | International Journal of Care and Caring
Raghav Soni, Taka‐Aki Asoh, Yu‐I Hsu, Michiyo Shimamura, Hiroshi Uyama,
We prepared a cellulose nanofiber reinforced retrograded starch film that had adequate mechanical properties and water durability. Non-retrograded tapioca starch (NRS) and retrograded tapioca starch (RS) were blended with TEMPO-oxidized cellulose nanofiber (TCNF) in different weight ratios. Subsequently, the suspensions were cast into films using a solution casting method. It was demonstrated that TCNF/RS films exhibited reduced swelling in water and enhanced mechanical strength compared to TCNF/NRS ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2020 - Elsevier BV | Polymer Degradation and Stability
Aki Shimamura, Arri Priimägi, Jun‐ichi Mamiya, Tomiki Ikeda, Yanlei Yu, Christopher J. Barrett, Atsushi Shishido,
The photomechanical behavior of cross-linked azobenzene-containing liquid-crystalline polymer films was investigated by means of simultaneous measurement of their optical and mechanical properties. The connection between photoisomerization of the azobenzene moieties, photoinduced change in molecular alignment, photoinduced stress generation, and macroscopic bending was analyzed. Upon UV irradiation, the films exhibited bending due to gradient in cis-azobenzene content, and subsequent unbending when ...
Tópico(s): Photochromic and Fluorescence Chemistry
2011 - American Chemical Society | ACS Applied Materials & Interfaces
Fuyuhiko Motoi, Kazuyuki Ishida, Fumiyoshi Fujishima, Shigeru Ottomo, Masaya Oikawa, Takaho Okada, Hiromune Shimamura, Shinichi Takemura, Fuminori Ono, Masanori Akada, Kei Nakagawa, Yu Katayose, Shinichi Egawa, Michiaki Unno,
Tópico(s): Cancer Genomics and Diagnostics
2013 - Springer Science+Business Media | Annals of Surgical Oncology
E. Giorgetti, Zhigang Yu, Jason P. Chua, Ryosuke Shimamura, Lili Zhao, Fan Zhu, Sriram Venneti, Maria Pennuto, Yuanfang Guan, Gene Hung, Andrew P. Lieberman,
Spinal and bulbar muscular atrophy (SBMA), a progressive degenerative disorder, is caused by a CAG/glutamine expansion in the androgen receptor (polyQ AR). Recent studies demonstrate that skeletal muscle is an important site of toxicity that contributes to the SBMA phenotype. Here, we sought to identify critical pathways altered in muscle that underlie disease manifestations in AR113Q mice. This led to the unanticipated identification of gene expression changes affecting regulators of carbohydrate ...
Tópico(s): RNA Research and Splicing
2016 - Cell Press | Cell Reports
Young Moon Yu, Valery I. Chani, Kiyoshi Shimamura, Katsuhiko Inaba, Tsuguo Fukuda,
Crack-free, transparent and colorless fiber single crystals with the size of 0.8–1.2 mm in diameter and 20–80 mm in length were grown from the melts of NaxCa2.5 − x2Mg2V3O12 where x = 0.0–1.0 by the micro-pulling-down method. The crystals grown from stoichiometric, NaCa2Mg2V3O12, and Na+-rich (x < 1.0) melt in air were transparent and gray colored. It was found that lower the x value, higher is the uniformity of lattice parameters of the solidified fraction. Maximal uniformity was achieved for the Ca2. ...
Tópico(s): Transition Metal Oxide Nanomaterials
1997 - Elsevier BV | Journal of Crystal Growth
Young Moon Yu, Valery I. Chani, Kiyoshi Shimamura, Tsuguo Fukuda,
Ca3LixNb(1.5 + x)Ga(3.5 − 2x)O12 garnets were synthesized and the conditions of the crystal growth are established. The measured lattice constants are about 12.54 Å irrespective of x. It was found that the Ca3Li0.275Nb1.775Ga2.95O12 garnet melts congruently at about 1450°C. Transparent and bubble-free crystals of x = 0.25 and 0.275 were grown by both modified micro-pulling down and Czochralski techniques in air using Pt crucibles. Results of solid state reaction data of other garnets are also discussed. ...
Tópico(s): Solid State Laser Technologies
1997 - Elsevier BV | Journal of Crystal Growth
Timothy J. Kamp, Gary E. Lyons,
... Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, Lensch MW, Cowan C, Hochedlinger K, Daley GQ. Disease-specific induced pluripotent stem cells. Cell. 2008; 134: 877–886.CrossrefMedlineGoogle Scholar6 Ebert AD, Yu J, Rose FF Jr, Mattis VB, Lorson CL, ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2009 - Lippincott Williams & Wilkins | Circulation Research
Elissa Furutani, Ankoor S. Shah, Yongdong Zhao, David Andorsky, Fatma Dedeoğlu, Amy E. Geddis, Zhou Yu, Towia A. Libermann, Kasiani C. Myers, Akiko Shimamura,
Abstract Shwachman–Diamond syndrome (SDS) is an autosomal recessive multisystem disorder characterized by exocrine pancreatic dysfunction, bone marrow failure, and leukemia predisposition. Approximately 90% of cases are due to biallelic mutations in the Shwachman–Bodian–Diamond ( SBDS ) gene. Additional phenotypic features variably associated with SDS include skeletal, neurologic, hepatic, cardiac, endocrine, and dental abnormalities. We report five subjects with SDS who developed a range of inflammatory ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2020 - Wiley | American Journal of Medical Genetics Part A
Itaru Kushima, Branko Aleksić, Masahiro Nakatochi, Teppei Shimamura, Takashi Okada, Yota Uno, Mako Morikawa, Kanako Ishizuka, Tomoko Shiino, Hiroki Kimura, Yuko Arioka, Akira Yoshimi, Yuto Takasaki, Yanjie Yu, Yukako Nakamura, Maeri Yamamoto, Tetsuya Iidaka, Shuji Iritani, Toshiya Inada, Nanayo Ogawa, Emiko Shishido, Youta Torii, Naoko Kawano, Yutaka Omura, Toru Yoshikawa, Tokio Uchiyama, Toshimichi Yamamoto, Masashi Ikeda, Ryota Hashimoto, Hidenaga Yamamori, Yuka Yasuda, Toshiyuki Someya, Yuichiro Watanabe, Jun Egawa, Ayako Nunokawa, Masanari Itokawa, Makoto Arai, Mitsuhiro Miyashita, Akiko Kobori, Michio Suzuki, Tsutomu Takahashi, Masahide Usami, Masaki Kodaira, Kyota Watanabe, Tsukasa Sasaki, Hitoshi Kuwabara, Mamoru Tochigi, Fumichika Nishimura, Hidenori Yamasue, Yosuke Eriguchi, Seico Benner, Masaki Kojima, Walid Yassin, Toshio Munesue, Shigeru Yokoyama, Ryo Kimura, Yasuko Funabiki, Hirotaka Kosaka, Makoto Ishitobi, Tetsuro Ohmori, Shusuke Numata, Takeo Yoshikawa, Tomoko Toyota, Kazuhiro Yamakawa, Toshimitsu Suzuki, Yushi Inoue, Kentaro Nakaoka, Yu-ichi Goto, Masumi Inagaki, Naoki Hashimoto, Ichiro Kusumi, Shuraku Son, Toshiya Murai, Tempei Ikegame, Naohiro Okada, Kiyoto Kasai, Shohko Kunimoto, Daisuke Mori, Nakao Iwata, Norio Ozaki,
Compelling evidence in Caucasian populations suggests a role for copy-number variations (CNVs) in autism spectrum disorder (ASD) and schizophrenia (SCZ). We analyzed 1,108 ASD cases, 2,458 SCZ cases, and 2,095 controls in a Japanese population and confirmed an increased burden of rare exonic CNVs in both disorders. Clinically significant (or pathogenic) CNVs, including those at 29 loci common to both disorders, were found in about 8% of ASD and SCZ cases, which was significantly higher than in controls. ...
Tópico(s): Genomics and Rare Diseases
2018 - Cell Press | Cell Reports
Takashi Kubo, Masahiro Takahata, Kosei Terada, Kazuya Mori, Yu Arita, Yasushi Ino, Yoshiki Matsuo, Hironori Kitabata, Yasutsugu Shiono, Kunihiro Shimamura, Takeyoshi Kameyama, Hiroki Emori, Yosuke Katayama, Takashi Tanimoto, Takashi Akasaka,
A fractional flow reserve (FFR) between 0.75 and 0.80 constitutes a "gray zone" for clinical decision-making in coronary artery disease. We compared long-term outcomes of percutaneous coronary intervention (PCI) using drug-eluting stents vs. medical therapy for coronary stenosis with gray zone FFR. Methods and Results: We retrospectively investigated the clinical outcomes of 263 patients with gray zone FFR: 78 patients in the PCI group and 185 patients in the medical therapy group. During a median ...
Tópico(s): Cardiac Imaging and Diagnostics
2018 - Japanese Circulation Society | Circulation Journal
Mayuko Tsujimura, Hiroo Ide, Wenwei Yu, Naonori Kodate, Mina Ishimaru, Atsuko Shimamura, Sayuri Suwa,
Purpose This study aims to compare the level of needs for home-care robots amongst older adults, family caregivers and home-care staff and clarify the factors constituting these needs. Design/methodology/approach A cross-sectional, anonymous questionnaire survey was administered. It included 52 items related to needs for home-care robots rated on a four-point Likert scale. Means and standard deviations were calculated, and the Kruskal-Wallis test was performed for each item. Factor analysis was ...
Tópico(s): Persona Design and Applications
2020 - Emerald Publishing Limited | Journal of Enabling Technologies
А. Г. Родников, A. G. Gainanov, B. V. Yermakov, V. M. Kovylin, В. А. Селиверстов, Ya. B. Smirnov, P. A. Stroev, Yu. K. Shchukin, Tomoya Kato, Hideki Shimamura,
Tópico(s): Methane Hydrates and Related Phenomena
1985 - Springer Science+Business Media | Marine Geophysical Research
Kunyu Zhao, Huarong Zeng, Song Hong-Zhang, Hui Sen-Xing, Guorong Li, Yin Qing-Rui, Kiyoshi Shimamura, Chinna Venkadasamy Kannan, Encarnación A. García Víllora, Shunji Takekawa, Kenji Kitamura,
... Ferroelectric Domains by Atomic Force Microscopy, Zhao Kun-Yu, Zeng Hua-Rong, Song Hong-Zhang, Hui Sen-Xing, Li Guo-Rong, Yin Qing-Rui, Kiyoshi Shimamura, Chinna Venkadasamy Kannan, Encarnacion Antonia Garcia Villora, Shunji ...
Tópico(s): Acoustic Wave Resonator Technologies
2008 - Institute of Physics | Chinese Physics Letters
Cassandra R. Harapas, Kim S. Robinson, Kenneth Lay, Jasmine C. Wong, Ricardo Moreno Traspas, Nasrin Nabavizadeh, Annick Rass-Rothschild, Bertrand Boisson, Scott Drutman, Pawat Laohamonthonkul, Devon Bonner, Jingwei Rachel Xiong, Mark D. Gorrell, Sophia Davidson, Chien‐Hsiung Yu, Mark D. Fleming, Jonas Gudera, Jerry Stein, Miriam Ben-Harosh, Emily Groopman, Akiko Shimamura, Hannah Tamary, Hülya Kayserili, Nevin Hatipoğlu, Jean‐Laurent Casanova, Jonathan A. Bernstein, Franklin L. Zhong, Seth L. Masters, Bruno Reversade,
Dipeptidyl peptidase 9 (DPP9) is a direct inhibitor of NLRP1, but how it affects inflammasome regulation in vivo is not yet established. Here, we report three families with immune-associated defects, poor growth, pancytopenia, and skin pigmentation abnormalities that segregate with biallelic
Tópico(s): Ubiquitin and proteasome pathways
2022 - American Association for the Advancement of Science | Science Immunology
Martin Schüler, Ella Bossy‐Wetzel, Joshua C. Goldstein, Patrick Fitzgerald, Douglas R. Green,
... 2033-2045Crossref PubMed Scopus (735) Google Scholar,32.Yu Y. Little J.B. Cancer Res. 1998; 5: 4277-4281Google Scholar, 33.Ding H.-F. McGill G. Rowan S. Schmaltz C. Shimamura A. Fisher D.E. J. Biol. Chem. 1998; ...
Tópico(s): Mitochondrial Function and Pathology
2000 - Elsevier BV | Journal of Biological Chemistry
Tsuyoshi Kadomatsu, Mitsuhisa Tabata, Yuichi Oike,
... 3), 603– 610. 11 Ono M, Shimizugawa T, Shimamura M, Yoshida K, Noji-Sakikawa C, Ando Y, Koishi R & Furukawa H (2003) Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3): ANGPTL3 is cleaved and activated in vivo. J Biol Chem 278, 41804– 41809. 12 Ge H, Cha JY, Gopal H, Harp C, Yu X, Repa JJ & Li C (2005) Differential regulation ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2010 - Wiley | FEBS Journal
Hironori Nakagami, Ryuichi Morishita,
... Watanabe R, Suzuki JI, Wakayama K, Maejima Y, Shimamura M, Koriyama H, Nakagami H, Kumagai H, Ikeda Y, Akazawa H, Morishita R, Komuro I, Isobe M. A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction.Sci Rep. 2017; 7:43920. doi: 10.1038/srep43920CrossrefMedlineGoogle Scholar19. Chen X, Qiu Z, Yang S, Ding D, Chen F, Zhou Y, Wang M, Lin J, Yu X, Zhou Z, Liao Y. Effectiveness and safety ...
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2018 - Lippincott Williams & Wilkins | Hypertension
Masamichi Mizuma, Fuyuhiko Motoi, Kazuyuki Ishida, Fumiyoshi Fujishima, Shigeru Ottomo, Masaya Oikawa, Takaho Okada, Hiromune Shimamura, Shinichi Takemura, Fuminori Ono, Masanori Akada, Kei Nakagawa, Yu Katayose, Shinichi Egawa, Michiaki Unno,
283 Background: Although surgical resection is the only curative treatment for pancreatic ductal adenocarcinoma (PDAC), recurrence rates are very high even if complete resection is performed. Accordingly, a new therapeutic strategy against PDAC is needed. Combination with gemcitabine and S-1 (GS) as first line chemotherapy is promising. The purpose of this study is to evaluate the feasibility and efficacy of GS for resectable and borderline PDAC in the neoadjuvant chemotherapy (NAC). Methods: This ...
Tópico(s): Renal cell carcinoma treatment
2014 - Lippincott Williams & Wilkins | Journal of Clinical Oncology