Birgit A. Helm, Ian Sayers, Adrian Higginbottom, Denise Cantarelli Machado, Yan Ling, Khalid Ahmad, Eduardo A. Padlan, Anne Wilson,
We have investigated the capacity of N- and C-terminally truncated and chimeric human (h) IgE-derived peptides to inhibit the binding of 125 I-labeled hIgE, and to engage cell lines expressing high and low affinity receptors (FcεRI/II). The peptide sequence Pro 343 -Ser 353 of the hCε3 domain is common to all hε-chain peptides that recognize hFcεRI. This region in IgE is homologous to the A loop in Cγ2 that engages the rat neonatal IgG receptor. Optimum FcεRI occupancy by hIgE occurs at pH 6.4, with ...
Tópico(s): Glycosylation and Glycoproteins Research
1996 - Elsevier BV | Journal of Biological Chemistry
Liuber Yans Machado Zaldívar, Madeline Blanco, Marta Dubed, Héctor M. Díaz, Nancy Ruíz, Neysi Váldes, D Romay, Leonor Lobaina,
Knowledge of the genetic diversity of HIV-1 constitutes a fundamental premise in the epidemiological surveillance. In the present study, the HIV-1 genetic variability from 142 Cuban patients who were diagnosed with HIV-1 infection during 2009 and 2010 was determined. HIV-1 subtypes were determined by partial RT-PCR and sequencing of the HIV-1 pol gene. The phylogenetic analysis showed that 47 (33.1 %) samples were subtypes B and 95 (66.9 %) were non-B subtypes, where G, H, and C subtypes, as well as the ...
Tópico(s): HIV/AIDS drug development and treatment
2011 - Mary Ann Liebert, Inc. | AIDS Research and Human Retroviruses
Liuber Yans Machado Zaldívar, Marta Dubed, Héctor M. Díaz, Nancy Ruíz, D Romay, Neysi Váldes, Madeline Blanco, Eladio Silva,
Knowledge of the associated mutations to transmitted drug resistance (TDR) in strains of human immunodeficiency virus type 1 (HIV-1) constitutes a fundamental premise in epidemiological surveillance. In this present study, TDR from 200 Cuban patients who were diagnosed with HIV-1 between 2009 and 2011 was analyzed. By partial reverse transcriptase polymerase chain reaction (RT-PCR) and sequencing of the HIV pol gene, an HIV subtype and transmitted resistance profile were determined. The prevalence ...
Tópico(s): HIV Research and Treatment
2012 - Mary Ann Liebert, Inc. | AIDS Research and Human Retroviruses
Paula Cíntia Machado Sampaio, Yan Garcia Lira, Hellen Yuki Umemura Ribeiro, Fernanda de Paula Moreira, Maitê Silva Martins Gadelha, Sérgio Ferreira Santos da Cruz,
Background: Poncet's disease is a rare syndrome characterized by articular impairment in a form of rare tuberculid.One of the theories of its cause involves an autoimmune response induced by the intravesical administration of the Calmette-Guerin Bacillus or the treatment of bladder carcinoma.Furthermore, there may be an appearance of oligoarticular or polyarticular arthritis, beginning 1-3 months after the start of therapy.Few physicians know the disease and the literature related to that syndrome ...
Tópico(s): Infectious Disease Case Reports and Treatments
2017 - BioMed Central | BMC Research Notes
Produção Nacional
Revisado por pares
Saurav Bhattacharya, Fernando Hernández, Mariana Ferreira Alves, Raquel Moura Machado, Yan-Yan Sun, Meng‐Ru Wang, Chao-Bin Zhang, Jian‐Hua Hao,
Abstract Invasive alien plants threaten biodiversity across the world. Erigeron canadensis (horseweed) is one of the most problematic agricultural weeds and represents a classic example of intercontinental invasion. Here, we studied the genetic diversity and population structure of invasive alien populations from the Jiangsu and Zhejiang Provinces in China and native populations from Alabama, in the USA. We used 10 polymorphic SSR loci to genotype 312 individuals from 5 native and 5 invasive populations ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2022 - Oxford University Press | Journal of Plant Ecology
Produção Nacional
Revisado por pares
Lesly Calderón, Elisa Facenda, Liuber Yans Machado Zaldívar, Keiko Uyema, Dúnia Rodriguez, Eliane Gomez, Y. Martínez, Bárbara Gonzalez, Virgilio Bourg, Carlos Álvarez, Anselmo Otero, Momtchilo Russo, Alexis Labrada, María E. Lanio,
Liposomes are non toxic and biodegradable lipid vesicles, which are safe and effective adjuvants to induce Th1-skewed immune response. Therefore, the encapsulation of allergens into liposomes could be an attractive alternative for specific allergy immunotherapy. Previously, we obtained DPPC iposomes encapsulating purified allergens from Dermatophagoides siboney, with suitable stability and extremely reduced allergenicity. In this study, Balb/c mice were immunized with allergens ncapsulated into ...
Tópico(s): Food Allergy and Anaphylaxis Research
2005 - Elsevier BV | Vaccine
Liuber Yans Machado Zaldívar, Madeline Blanco, Laura Svidler López, Héctor M. Díaz, Marta Dubed, Neisy Valdés, Enrique Noa, Lilibeth Angélica Zambrano Martínez, Maria Perez, D Romay, Caridad B. Rivero, José Joanes, Isis Cancio, M I Lantero, Mireida Rodríguez,
Background The World Health Organization (WHO) recommends a method to estimate nationally representative pretreatment HIV drug resistance (PDR) in order to evaluate the effectiveness of first -line treatments. The objective of the present study was to determine the prevalence of PDR in Cuban adults infected with HIV-1. Materials and methods A cross-sectional study in Cuban adults infected with HIV-1 over 18 years was conducted. The probability proportional to size method for the selection of municipalities ...
Tópico(s): HIV/AIDS Research and Interventions
2019 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Frederico Sander Mansur Machado, Zhi Zhang, Yan Su, Paul de Goede, Remi Jansen, Ewout Foppen, Cândido Celso Coimbra, Andries Kalsbeek,
Daily cyclic changes in environmental conditions are key signals for anticipatory and adaptive adjustments of most living species, including mammals. Lower ambient temperature stimulates the thermogenic activity of brown adipose tissue (BAT) and skeletal muscle. Given that the molecular components of the endogenous biological clock interact with thermal and metabolic mechanisms directly involved in the defense of body temperature, the present study evaluated the differential homeostatic responses ...
Tópico(s): Spaceflight effects on biology
2018 - Frontiers Media | Frontiers in Endocrinology
Liyuan Yang, Carlos A. Machado, Xiaodong Dang, Yan‐Qiong Peng, Da‐Rong Yang, Da‐Yong Zhang, Wan‐Jin Liao,
Differences in breeding system are associated with correlated ecological and morphological changes in plants. In Ficus, dioecy and monoecy are strongly associated with different suites of traits (tree height, population density, fruiting frequency, pollinator dispersal ecology). Although approximately 30% of fig species are pollinated by multiple species of fig-pollinating wasps, it has been suggested that copollinators are rare in dioecious figs. Here, we test whether there is a connection between ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2014 - Oxford University Press | Evolution
Produção Nacional
Revisado por pares
Jiwen Fan, Daniel Rosenfeld, Yuwei Zhang, Scott Giangrande, Zhanqing Li, Luiz A. T. Machado, Scot T. Martin, Yan Yang, Jian Wang, Paulo Artaxo, Henrique M. J. Barbosa, Ramon Campos Braga, J. M. Comstock, Zhe Feng, Wenhua Gao, Helber Barros Gomes, Fan Mei, Christopher Pöhlker, Mira L. Pöhlker, Ulrich Pöschl, Rodrigo Augusto Ferreira De Souza,
Up with ultrafine aerosol particles Ultrafine aerosol particles (smaller than 50 nanometers in diameter) have been thought to be too small to affect cloud formation. Fan et al. show that this is not the case. They studied the effect of urban pollution transported into the otherwise nearly pristine atmosphere of the Amazon. Condensational growth of water droplets around the tiny particles releases latent heat, thereby intensifying atmospheric convection. Thus, anthropogenic ultrafine aerosol particles ...
Tópico(s): Atmospheric Ozone and Climate
2018 - American Association for the Advancement of Science | Science
Produção Nacional
Revisado por pares
Çharles N. Bernstein, Siew C. Ng, Rupa Banerjee, Flávio Steinwurz, Bo Shen, Franck Carbonnel, Saeed Hamid, Ajit Sood, Jesús K. Yamamoto‐Furusho, Anne M. Griffiths, Eric I. Benchimol, Simon Travis, Susana Lopes, David T. Rubin, Gilaad G. Kaplan, David Armstrong, Richard B. Gearry, M Masudur Rahman, Mostafa Noor Mohsin, Andréa Vieira, Nayara Carvalho Salgado, Marta Brenner Machado, Hao Wu, Joyce Wing Yan Mak, Yinglei Miao, Murdani Abdullah, Yehuda Chowers, Elly O. Ogutu, Smita Devani, Suk‐Kyun Yang, Mahmoud Omar, Khean‐Lee Goh, Ida Hilmi, Raja Affendi Raja Ali, Than Than Aye, Tin Moe Wai, Neeraj Joshi, Zaigham Abbas, Fernando Magro, Jose D. Sollano, Esther A. Torres, Syed Adnan Mohiuddin, Mircea Diculescu, Majid A. Almadi, David Ong, Gillian Watermeyer, Navarathne Metthananda, Shu‐Chen Wei, Julajak Limsrivilai, Nonthalee Pausawasdi, Pises Pisepongsa, Gursimran Kochhar, Ximena Rodríguez, Dao Viet,
Persons with inflammatory bowel disease (IBD) may be particularly vulnerable to COVID-19 either because of their underlying disease or its management. Guidance has been presented on the management of persons with IBD in the time of this pandemic by different groups. We aimed to determine how gastroenterologists around the world were approaching the management of IBD.Members of the World Gastroenterology Organization (WGO) IBD Task Force contacted colleagues in countries largely beyond North America ...
Tópico(s): COVID-19 Clinical Research Studies
2020 - Oxford University Press | Inflammatory Bowel Diseases
Paul Arkell, Celia Gusmão, Sarah Sheridan, Maria Y Tanesi, Nelia Gomes, Tessa Oakley, Johanna Wapling, Lucsendar Alves, Stacey Kopf, Nevio Sarmento, Ismael Da Costa Barreto, Salvador Amaral, Anthony Draper, Danina Coelho, Helio Guterres, Antonio Salles, Filipe de Neri Machado, Nicholas Fancourt, Jennifer Yan, Ian Marr, Kristine Macartney, Joshua Francis,
Background Serosurveillance can be used to investigate the extent and distribution of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within a population. Characterisation of humoral immune responses gives insight into whether immunity is infection- or vaccine-derived. Methods A longitudinal study of health care workers (HCWs) in Dili, Timor-Leste, was conducted during vaccine rollout (ChAdOx1) and a concurrent SARS-CoV-2 outbreak. Results A total of 324 HCWs were included ...
Tópico(s): COVID-19 epidemiological studies
2022 - Elsevier BV | International Journal of Infectious Diseases
Xiaojun Zhang, Ana Carolina Dantas Machado, Yuan Chun Ding, Yongheng Chen, Yan Lü, Yankun Duan, Kenneth Tham, Lin Chen, Remo Rohs, Peter Z. Qin,
Abstract The tumor suppressor protein p53 regulates numerous signaling pathways by specifically recognizing diverse p53 response elements (REs). Understanding the mechanisms of p53-DNA interaction requires structural information on p53 REs. However, such information is limited as a 3D structure of any RE in the unbound form is not available yet. Here, site-directed spin labeling was used to probe the solution structures of REs involved in p53 regulation of the p21 and Bax genes. Multiple nanometer ...
Tópico(s): Electron Spin Resonance Studies
2013 - Oxford University Press | Nucleic Acids Research
Ying Shen, Zhifei Yin, Yabei Fan, Chiun-Fan Chen, Wenjun Dai, Wenchao Yi, Yongqiang Li, Wentong Zhang, Yuting Zhang, Rong Bian, Yan Huang, Sérgio Machado, Ti‐Fei Yuan, Chunlei Shan,
Background: Contralaterally controlled functional electrical stimulation (CCFES) is an innovative method to improve upper extremity functions after stroke. Objective: To compare the effects of CCFES versus neuromuscular electrical stimulation (NMES) on the upper extremity functions in patients with stroke. Methods: Sixty patients with stroke were randomly assigned into CCFES group (n=30) or NMES group (n=30). All patients were also treated with conventional medical treatment and rehabilitation training. ...
Tópico(s): Transcranial Magnetic Stimulation Studies
2015 - Bentham Science Publishers | CNS & Neurological Disorders - Drug Targets
Charlotte Fenioux, Baptiste Abbar, Samia Boussouar, Marie Bretagne, John R. Power, Javid J. Moslehi, Paul Gougis, Damien Amelin, Agnès Dechartres, Lorenz Lehmann, Pierre‐Yves Courand, Jennifer Cautela, Joachim Alexandre, Adrien Procureur, Antoine Rozes, Sarah Léonard-Louis, Juan Qin, Nausheen Akhter, Nazanin Aghel, Kingsley Amidi, Élizabeth Anderson, Dimitri Arangalage, Mandar A. Aras, Aarti Asnani, Lauren A. Baldassarre, Rocio Barovila, Ana Sofia Barroso, Wendy Bottinor, Anissa Bouali, Eve Cariou, Wei‐Ting Chang, Richard K. Cheng, Shanthini M. Crusz, Anita Deswal, Pierre‐Yves Dietrich, Grace K. Dy, Clémence Docq, Steven M. Ewer, Suran L. Fernando, Danette L. Flint, Roberta Florido, Satoshi Fukushima, Elena Galli, Elizabeth Gaughan, Manhal Habib, Andrew Haydon, Lucie Heinzerling, Osnat Itzhaki Ben Zadok, N. Issa, Anja Karlstaedt, Kazuo Kitagawa, Michael Layoun, Michal Laufer‐Perl, Carrie Lenneman, Darryl P. Leong, Chloé Lesiuk, Joshua Levenson, Teresa López‐Fernández, Yan Liu, Kristen Machado, Pedro Moliner, Ryota Morimoto, Michel Obéid, Anna Narezkina, Nicolas L. Palaskas, Giovanni Peretto, Nicolas Piriou, Juan Carlos Plana, Peter P. Rainer, Maxime Robert‐Halabi, Fanny Rocher, Eugenia Rota, François Roubille, Theresa Ruf, Shahneen Sandhu, Francis Sanjeev, Nobuhiko Seki, Kazuko Tajiri, Yuichi Tamura, Franck Thuny, Romain Trésorier, Isik Turker, Ellen Warner, Vlad G. Zaha, Han Zhu, Rémi Cheynier, Bénédicte Charmeteau-De Muylder, Alban Redheuil, Florence Tubach, Jacquès Cadranel, Audrey Milon, Stéphane Éderhy, Thomas Similowski, Douglas B. Johnson, Ian Pizzo, Toniemarie Catalan, Olivier Benveniste, Salim S. Hayek, Yves Allenbach, Michèlle Rosenzwajg, Charles Dolladille, Joe-Élie Salem,
Tópico(s): Myasthenia Gravis and Thymoma
2023 - Nature Portfolio | Nature Medicine
Richard W. Smiley, Stephen Machado, Jennifer A. Gourlie, Larry Pritchett, Guiping Yan, Erling E. Jacobsen,
There is interest in converting rainfed cropping systems in the Pacific Northwest from a 2-year rotation of winter wheat and cultivated fallow to direct-seed (no-till) systems that include chemical fallow, spring cereals, and food legume and brassica crops. Little information is available regarding effects of these changes on plant-parasitic nematodes. Eight cropping systems in a low-precipitation region (<330 mm) were compared over 9 years. Each phase of each rotation occurred each year. The density ...
Tópico(s): Legume Nitrogen Fixing Symbiosis
2012 - American Phytopathological Society | Plant Disease
Richard W. Smiley, Stephen Machado, Jennifer A. Gourlie, Larry Pritchett, Guiping Yan, Erling E. Jacobsen,
There is interest in converting the 2-year rotation of rainfed winter wheat with cultivated fallow in the Pacific Northwest of the United States into direct-seed (no-till) systems that include chemical fallow, spring cereals, and food-legume and brassica crops. Eight cropping systems in a low-precipitation region (<330 mm) were compared over 9 years to determine effects of changes on diseases. Fusarium crown rot was more prevalent in wheat following cultivated than chemical fallow, and Rhizoctonia ...
Tópico(s): Plant Pathogens and Fungal Diseases
2012 - American Phytopathological Society | Plant Disease
Allan Lazarovici, Tianyin Zhou, Anthony Shafer, Ana Carolina Dantas Machado, Todd Riley, Richard Sandstrom, Peter J. Sabo, Yan Lü, Remo Rohs, J Stamatoyannopoulos, Harmen J. Bussemaker,
DNA binding proteins find their cognate sequences within genomic DNA through recognition of specific chemical and structural features. Here we demonstrate that high-resolution DNase I cleavage profiles can provide detailed information about the shape and chemical modification status of genomic DNA. Analyzing millions of DNA backbone hydrolysis events on naked genomic DNA, we show that the intrinsic rate of cleavage by DNase I closely tracks the width of the minor groove. Integration of these DNase ...
Tópico(s): Cancer-related gene regulation
2013 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Produção Nacional
Revisado por pares
Moacyr Magno Palmeira, Hellen Yuki Umemura Ribeiro, Yan Garcia Lira, Fernando Octávio Machado Jucá Neto, Ivone Aline da Silva Rodrigues, Letícia Nazareth Fernandes da Paz, Maria da Conceição Nascimento Pinheiro,
Cardiac complications constitute a rare clinical manifestation of cytomegalovirus (CMV) infection. This virus is usually asymptomatic in immunocompetent individuals. We report a case of myocarditis and cardiac insufficiency due to primary CMV infection. Serological tests by using ELISA method showed positive results for the virus. A 41-year-old man with no prior comorbidities presenting with dyspnoea, fever, and oedema was admitted to the cardiac emergency service. He had fever and dry cough, which ...
Tópico(s): Herpesvirus Infections and Treatments
2016 - BioMed Central | BMC Research Notes
Produção Nacional
Revisado por pares
Gleice C. M. Germano, Yan D. R. Machado, Lucas M. Martinho, Susete N. Fernandes, Antonio M.L.M. Costa, Édison Pécoraro, Anderson S. L. Gomes, Isabel C. S. Carvalho,
In this work, we developed and investigated a random laser based on rhodamine6G (Rh6G) in ethylene glycol (EG) solution with varying cellulose nanocrystalline (CNC) needles as scatterers in the lasing media. Besides the suspension-in-cuvette scheme, an alternative configuration was also employed: a dye-CNC flexible self-supported thick-film (70 µm) random laser made by drop casting of the C N C s + R h 6 G + h y d r o x y p r o p y l cellulose suspension. In relation to conventional scatterers, the biodegradable ...
Tópico(s): Photonic Crystals and Applications
2019 - Optica Publishing Group | Journal of the Optical Society of America B
John D. Williams, Stewart B. Wuest, D. S. Robertson,
... j.aeolia.2010.03.003 24Smiley, R.W., Machado, S., Gourlie, J.A., Pritchett, L.C., Yan, G., and Jacobsen, E.E.. 2013. Influence of ...
Tópico(s): Soil erosion and sediment transport
2015 - Wiley | Soil Science Society of America Journal
David Dilworth, Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta, Matthew R. Marunde, Suzanne Ackloo, Raquel A. C. Machado, Aliakbar Khalili Yazdi, Dominic D. G. Owens, Victoria Vu, Yan Nie, Mona Alqazzaz, Edyta Marcon, Fengling Li, Irene Chau, Albina Bolotokova, Qin Su, Ming Lei, Yanli Liu, Magdalena M. Szewczyk, Aiping Dong, Sina Kazemzadeh, Tigran M. Abramyan, Irina K. Popova, Nathan W Hall, Matthew J. Meiners, Marcus A. Cheek, Elisa Gibson, Dmitri Kireev, Jack Greenblatt, Michael‐Christopher Keogh, Jinrong Min, Peter J. Brown, Masoud Vedadi, C.H. Arrowsmith, Dalia Baršytė-Lovejoy, Lindsey I. James, Matthieu Schapira,
Nuclear receptor-binding SET domain-containing 2 (NSD2) is the primary enzyme responsible for the dimethylation of lysine 36 of histone 3 (H3K36), a mark associated with active gene transcription and intergenic DNA methylation. In addition to a methyltransferase domain, NSD2 harbors two proline-tryptophan-tryptophan-proline (PWWP) domains and five plant homeodomains (PHDs) believed to serve as chromatin reading modules. Here, we report a chemical probe targeting the N-terminal PWWP (PWWP1) domain of ...
Tópico(s): Epigenetics and DNA Methylation
2021 - Nature Portfolio | Nature Chemical Biology
Brendon H Cooper, Ana Carolina Dantas Machado, Yan Gan, Oscar M. Aparicio, Remo Rohs,
Abstract Quantifying the nucleotide preferences of DNA binding proteins is essential to understanding how transcription factors (TFs) interact with their targets in the genome. High-throughput in vitro binding assays have been used to identify the inherent DNA binding preferences of TFs in a controlled environment isolated from confounding factors such as genome accessibility, DNA methylation, and TF binding cooperativity. Unfortunately, many of the most common approaches for measuring binding preferences ...
Tópico(s): CRISPR and Genetic Engineering
2023 - Oxford University Press | Nucleic Acids Research
Produção Nacional
Revisado por pares
Yan D. R. Machado, Gleice C. M. Germano, Édison Pécoraro, Antonio M.L.M. Costa, Isabel C. S. Carvalho,
Tópico(s): Optical Polarization and Ellipsometry
2023 - Elsevier BV | Optical Materials
Giacomo Salvadore, Jan Willem van der Veen, Yan Zhang, Stefano Marenco, Rodrigo Machado‐Vieira, Jacqueline Baumann, Lobna Ibrahim, David A. Luckenbaugh, Jun Shen, Wayne C. Drevets, Carlos A. Zarate,
Abstract Amino-acid neurotransmitter system dysfunction plays a major role in the pathophysiology of major depressive disorder (MDD). We used proton magnetic resonance spectroscopy (1H-MRS) to investigate whether prefrontal levels of amino-acid neurotransmitters predict antidepressant response to a single intravenous infusion of the N-methyl-d-aspartate (NMDA) antagonist ketamine in MDD patients. Fourteen drug-free patients with MDD were scanned 1–3 d before receiving a single intravenous infusion ...
Tópico(s): Neuroscience and Neuropharmacology Research
2011 - University of Oxford | The International Journal of Neuropsychopharmacology
Yan Ducharme, Ross Stevenson, Nuno Machado,
The Lacorne Block in the Southern Volcanic Zone of the Abitibi Subprovince is composed of interleaved metavolcanic and metasedimentary rocks that are intruded by syn- to posttectonic diorites, granodiorites, and granites. These rocks form the Lacorne, Lamotte, and Preissac plutons, which can be divided into an early suite of dioritic–granodioritic rocks and a later suite of S-type, leucocratic granites with an estimated age of 2640 Ma. This study presents Sm–Nd data and U–Pb monazite and titanite ...
Tópico(s): Geochemistry and Geologic Mapping
1997 - NRC Research Press | Canadian Journal of Earth Sciences
Produção Nacional
Revisado por pares
Mariana Bezamat, Juliana Feltrin de Souza, Fernanda Mafei Félix da Silva, Emilly Godinho Corrêa, Aluhê Lopes Fatturi, João Armando Brancher, Flávia Martinez de Carvalho, Tayla Cavallari, Laís Bertolazo, Cleber Machado‐Souza, Mine Koruyucu, Merve Bayram, Andrea Racic, Benjamin Harrison, Yan Y. Sweat, Ariadne Letra, Deborah Studen‐Pavlovich, Figen Seymen, Brad A. Amendt, Renata Iani Werneck, Marcelo C. Costa, Adriana Modesto, Alexandre R. Vieira,
Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur when there are disturbances during the mineralization or maturation stage of amelogenesis. Both genetic and environmental factors have been suggested to play roles in MIH’s development, but no conclusive risk factors have shown the source of the ...
Tópico(s): Oral microbiology and periodontitis research
2021 - Public Library of Science | PLoS ONE
Hui-Fang Xue, Jian-Ning Fu, L. Fox Machado, Jianrong Shi, Yutao Zhou, M. Zhang, R. Michel, Hongliang Yan, Jia-Shu Niu, Weikai Zong, Jie Su, A. Castro, C. Ayala-Loera, L. Altamirano-Dévora,
Bi-site time-series photometric and high-resolution spectroscopic observations were made for the double-mode high-amplitude $\delta$ Scuti star VX\ Hya. The fundamental frequency $f_{0}=4.4763\ \rm{c\ days^{-1}}$, the first overtone $f_{1}=5.7897\ \rm{c\ days^{-1}}$ and 23 harmonics and linear combinations of $f_{0}$ and $f_{1}$ are detected by pulsation analysis. From the spectroscopic data, we get $\rm{[Fe/H] = -0.2\pm0.1\ dex}$. The period change rate of the fundamental mode is obtained by using the Fourier- ...
Tópico(s): Astronomy and Astrophysical Research
2018 - IOP Publishing | The Astrophysical Journal
Andrew S. Mendiola, Jae Kyu Ryu, Sophia Bardehle, Anke Meyer‐Franke, Kenny Kean‐Hooi Ang, Chris Wilson, Kim M. Baeten, Kristina Hanspers, Mario Merlini, Sean Thomas, Mark A. Petersen, Alexander Williams, Reuben Thomas, Victoria A. Rafalski, Rosa Meza-Acevedo, Reshmi Tognatta, Zhaoqi Yan, Samuel J. Pfaff, Michael R. Machado, Catherine Bédard, Pamela E. Rios Coronado, Xiqian Jiang, Jin Wang, Michael A. Pleiss, Ari Green, Scott S. Zamvil, Alexander R. Pico, Benoit G. Bruneau, Michelle R. Arkin, Katerina Akassoglou,
Oxidative stress is a central part of innate immune-induced neurodegeneration. However, the transcriptomic landscape of central nervous system (CNS) innate immune cells contributing to oxidative stress is unknown, and therapies to target their neurotoxic functions are not widely available. Here, we provide the oxidative stress innate immune cell atlas in neuroinflammatory disease and report the discovery of new druggable pathways. Transcriptional profiling of oxidative stress–producing CNS innate ...
Tópico(s): Immune cells in cancer
2020 - Nature Portfolio | Nature Immunology
S. Abdullin, V. Abramov, B. S. Acharya, N. Adam, M. R. Adams, P. Adzic, N. Akchurin, U. Akgun, E. A. Albayrak, R. Alemany–Fernández, N. Almeida, G. Anagnostou, D. Andelin, E. W. Anderson, M. Anfreville, I. Aničin, G. Antchev, Ž. Antunović, R. Arcidiacono, M. W. Arenton, E. Auffray, S. Argirò, A. Askew, O. Atramentov, S. Ayan, M. Arcidy, S. Aydin, T. Aziz, M. M. Baarmand, K. Babich, S. Baccaro, D. Baden, S. Baffioni, M. N. Bakirci, M. Balazs, Sud. Banerjee, Sun. Banerjee, Robert L. Bard, D. Barge, V. E. Barnes, David Barney, L. Barone, A. Bartoloni, C. Baty, H. S. Bawa, G. Baiatian, D. V. Bandurin, S. Beauceron, K. W. Bell, G. Bencze, R. Benetta, Jean‐François Bercher, S. B. Beri, C. Bernet, L. Berntzon, U. Berthon, M. Besançon, B.L. Betev, R. Beuselinck, V. Bhatnagar, A. Bhatti, C. Biino, J. Blaha, P. Bloch, S. Blyth, A. Bodek, A. Bornheim, S. Böse, T. Bose, J. Bourotte, A. M. Brett, Robert M. Brown, D. Britton, H. S. Budd, M. Buehler, K. Burchesky, P. Busson, B. Camanzi, T. Camporesi, K. Cankoçak, Kenneth Carrell, E. Carrera Jarrin, N. Cartiglia, F. Cavallari, S. Çerçi, M. Cerutti, P. Chang, Y. H. Chang, C. Charlot, E. A. Chen, W. T. Chen, Z. Chen, S.R. Chendvankar, R. Chipaux, B. C. Choudhary, R. K. Choudhury, Y. S. Chung, W. Clarida, D. J. A. Cockerill, C. Combaret, S. Conetti, F. Cossutti, B. Cox, L. Cremaldi, P. Cushman, D. Cussans, I. Dafinei, J. Damgov, D. R. Da Silva Di Calafiori, G. Daskalakis, G. Davatz, A. David, P. de Barbaro, P. Debbins, K. Deiters, M. Déjardin, Marko Djordjević, M. Deliomeroglu, R. Della Negra, G. Della Ricca, D. Del Re, A. I. Demianov, A. De Min, D. Denegri, P. Depasse, T. de Visser, J. Descamps, P. V. Deshpande, J. Dı́az, M. Diemoz, E. Di Marco, Л. Дімітров, G. Dissertori, M. Dittmar, L. Djambazov, L. Dobrzyński, S. Drndarević, J. E. Duboscq, S. Dugad, I. Dumanoğlu, F. Duru, Dipanwita Dutta, M. Dželalija, I. Efthymiopoulos, J. E. Elias, A. Elliott-Peisert, H. El Mamouni, D. Elvira, I. Emeliantchik, S. C. Eno, A. Ershov, S. Ertürk, S. Esen, E. Eşkut, I. Evangelou, David L. Evans, B. Fabbro, J. L. Faure, J. Fay, A. Fenyvesi, F. Ferri, W. C. Fisher, P. Flower, D. Franci, G. Franzoni, J. Freeman, K. Freudenreich, W. Funk, S. Ganjour, Corrado Gargiulo, S. Gascon, M. Gataullin, V. Gaultney, H. Gamsizkan, V. Gavrilov, Y. Geerebaert, V. Genchev, F. X. Gentit, D. Gerbaudo, Y. Gershtein, A. Ghezzi, M. Ghodgaonkar, J. Gilly, A. Givernaud, S. V. Gleyzer, S. Gninenko, Alan S. Go, B. Gobbo, N. Godinović, N. Golubev, I. Golutvin, P. I. Goncharov, D. T. Gong, P. Govoni, N. Grant, P. Gras, T. Grassi, D. Green, R. J. S. Greenhalgh, A. Gribushin, Б. В. Гринев, L. Guevara Riveros, J.P. Guillaud, A. Gurtu, A. M. Guler, E. Gülmez, Kazım Gümüş, T. Haelen, S. Hagopian, V. Hagopian, M. Haguenauer, V. Halyo, G. Hamel de Monchenault, M Hansen, M. Hashemi, J. M. Hauptman, E. Hazen, H. F. Heath, A. Heering, A. Heister, B. K. Heltsley, John A. Hill, W. Hintz, R. Hirosky, P. R. Hobson, A. Honma, George W. S. Hou, Y. Hsiung, A. Hunt, M. Husejko, B. Ille, N. P. Ilyina, R. Imlay, D. Ingram, Q. Ingram, E. Isiksal, P. Jarry, C. Jarvis, C. Jeong, C. Jessop, K. F. Johnson, Julian R. Jones, D. Jovanovic, K. Kaadze, В. Качанов, V. Kaftanov, S. Kailas, V. Kalagin, A. Kalinin, S.D. Kalmani, D. J. Karmgard, S. K. Kataria, M. Kaur, M. Kaya, O. Kaya, A. Kayis Topaksu, R. G. Kellogg, B. W. Kennedy, A. Khmelnikov, H. J. Kim, I. Kisselevich, K. Kloukinas, O. Kodolova, J. Kohli, P. Kokkas, T. Kolberg, V. Kolossov, A. Korablev, Yu. P. Korneev, I. Kosarev, L. H. Kramer, N. Krasnikov, A. N. Krinitsyn, A. Krokhotin, D. Krpić, V. I. Kryshkin, Y. Kubota, A. Kubik, S. Kuleshov, Arun Kumar, P. Kumar, S. Kunori, C. M. Kuo, P. Kurt, P. Kyberd, A. Kyriakis, A. T. Laasanen, V. Ladygin, E. Laird, G. Landsberg, Á. László, C. Lawlor, D. Lazic, M. Lebeau, P. Lecomte, P. Lecoq,
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