Gail Amir, E. Rosenmann, Yoav Sherman, Ziv Greenfeld, Zvi Neʼeman, A. M. Cohen,
Tópico(s): Metabolism, Diabetes, and Cancer
2002 - Elsevier BV | Laboratory Investigation
Zev Levin, Yoav Yair, Baruch Ziv,
The occurrence of negative and positive ground flashes in Tel‐Aviv, Israel (32.05 N, 34.45 E) has been monitored through daily registrations of a CGR3‐SN5 lightning flash counter (Mackerras, 1985). Measurements were conducted from 1987 to 1995, with the most continuous data sets available for the period 1992–1995. The lightning data was augmented by radar measurements of the thunderclouds (starting from 1994) and by radiosonde data. It was found that the fraction R of positive lightning from the total ...
Tópico(s): Tree Root and Stability Studies
1996 - American Geophysical Union | Geophysical Research Letters
Itai Dattner, Yair Goldberg, Guy Katriel, Rami Yaari, Nurit Gal, Yoav Miron, Arnona Ziv, Rivka Sheffer, Yoram Hamo, Amit Huppert,
One of the significant unanswered questions about COVID-19 epidemiology relates to the role of children in transmission. This study uses data on infections within households in order to estimate the susceptibility and infectivity of children compared to those of adults. The data were collected from households in the city of Bnei Brak, Israel, in which all household members were tested for COVID-19 using PCR (637 households, average household size of 5.3). In addition, serological tests were performed ...
Tópico(s): Vaccine Coverage and Hesitancy
2021 - Public Library of Science | PLoS Computational Biology
Yoav O. Rosenberg, Ziv Sade, Jiwchar Ganor,
While the precipitation paths of the major ions (i.e., Ca2+, Na+, K+, Cl− and SO42−) during seawater evaporation have been extensively studied, the precipitation of minor solutes from evaporated seawater was not thoroughly studied. The present study aims to achieve a quantitative understanding of Sr2+, Ba2+ and Ra2+ removal from evaporated seawater, by exploring in-situ evaporation of seawater in a series of ponds of a salt plant. Seawater samples, at various degrees of evaporation, were collected ...
Tópico(s): Groundwater flow and contamination studies
2018 - Elsevier BV | Geochimica et Cosmochimica Acta
S. Shalev, Hadas Saaroni, T. Izsak, Yoav Yair, Baruch Ziv,
Abstract. The spatio-temporal distribution of lightning flashes over Israel and the neighboring area and its relation to the regional synoptic systems has been studied, based on data obtained from the Israel Lightning Location System (ILLS) operated by the Israel Electric Corporation (IEC). The system detects cloud-to-ground lightning discharges in a range of ~500 km around central Israel (32.5° N, 35° E). The study period was defined for annual activity from August through July, for 5 seasons in the ...
Tópico(s): Tropical and Extratropical Cyclones Research
2011 - Copernicus Publications | Natural hazards and earth system sciences
Orit Altaratz, Zev Levin, Yoav Yair and, Baruch Ziv,
This paper presents a study of the characteristics of lightning activity during the Cyprus low winter storms over the eastern coast of the Mediterranean. The focus is on changes in the nature of thunderstorms crossing the coastline from the sea into the northern and central parts of Israel, as manifested in their electrical activity. It is based on the Lightning Position and Tracking System (LPATS) measurements of lightning ground strikes during four winter seasons between 1995 and 1999. The spatial ...
Tópico(s): Meteorological Phenomena and Simulations
2003 - American Meteorological Society | Monthly Weather Review
M. Sklair-Levy, Pinhas Lebensart, Yakov H. Applbaum, Nilli Ramu, Arnold I. Freeman, David Gozal, Eitan Gross, Yoav Sherman, J Bar-Ziv, Eugine Libson,
Tópico(s): Pleural and Pulmonary Diseases
2001 - Springer Science+Business Media | Pediatric Radiology
Lotem Goldberg, Adi Ziv, Yoav Vardi, Shai Hadas, Tarek Zuabi, Lital Yeshareem, Tomer Gur, Shelly Steinling, Oded Scheuerman, Yoel Levinsky,
Social distancing and quarantines have major negative psychological implications. Our aim was to study the rate of pediatric hospitalizations due to anorexia nervosa (AN) during the first year of coronavirus disease 2019 (COVID-19) pandemic as compared to previous years, with regard to clinical and laboratory parameters. This is a retrospective study in a tertiary pediatric hospital in Israel. Data regarding inpatient hospitalizations due to AN were retrieved, then epidemiological, clinical, and laboratory ...
Tópico(s): Impact of Technology on Adolescents
2022 - Springer Science+Business Media | European Journal of Pediatrics
Shlomi Ziskin Ziv, Yoav Yair, Pinhas Alpert, Leenes Uzan, Yuval Reuveni,
The study of the diurnal variations of the total water vapor amount in an atmospheric column, also known as Precipitable Water Vapor (PWV) or Integrated Water Vapor (IWV), is highly significant in meteorology and climatology studies, yet very limited due to insufficient spatial and temporal in situ measurements. Nowadays, Global Navigation Satellite System (GNSS) ground receivers are used along with retrieval techniques in order to conduct high sample rate PWV estimations. Here, we present the annual ...
Tópico(s): Geophysics and Gravity Measurements
2020 - Elsevier BV | Atmospheric Research
Raz Bar‐Ziv, Yoav Voichek, Naama Barkai,
Chromatin is composed of DNA and histones, which provide a unified platform for regulating DNA-related processes, mostly through their post-translational modification. During DNA replication, histone arrangement is perturbed, first to allow progression of DNA polymerase and then during repackaging of the replicated DNA. To study how DNA replication influences the pattern of histone modification, we followed the cell-cycle dynamics of 10 histone marks in budding yeast. We find that histones deposited ...
Tópico(s): Epigenetics and DNA Methylation
2016 - Cold Spring Harbor Laboratory Press | Genome Research
Yoav Voichek, Raz Bar‐Ziv, Naama Barkai,
Genome replication introduces a stepwise increase in the DNA template available for transcription. Genes replicated early in S phase experience this increase before late-replicating genes, raising the question of how expression levels are affected by DNA replication. We show that in budding yeast, messenger RNA (mRNA) synthesis rate is buffered against changes in gene dosage during S phase. This expression homeostasis depends on acetylation of H3 on its internal K56 site by Rtt109/Asf1. Deleting ...
Tópico(s): Fungal and yeast genetics research
2016 - American Association for the Advancement of Science | Science
Raz Bar‐Ziv, Yoav Voichek, Naama Barkai,
Gene dosage becomes transiently imbalanced during DNA replication. In bacteria, expression increases immediately following replication, introducing growth rate-dependent biases that are capitalized for regulation. In eukaryotes, the effect of changes in gene dosage during DNA replication on expression is buffered. In budding yeast, buffering gene expression during DNA replication is chromatin based and is dependent on acetylation of H3K56 by Rtt109/Asf1. DNA replication perturbs the dosage balance ...
Tópico(s): Bacterial Genetics and Biotechnology
2016 - Elsevier BV | Trends in Genetics
N. Harats, Baruch Ziv, Yoav Yair, Vassiliki Kotroni, Uri Dayan,
Abstract. The FLASH EU funded project aims to observe, analyze and model lightning activity in thunderstorms for use in short term forecasting of flash floods in the Mediterranean region. Two new indices, aimed to assess the potential for heavy precipitation and flash-floods, are proposed and evaluated. The first is a lightning index – the MKI, which is a modified version of the KI-index. The applied index gives more weight to the lower- and mid-level relative humidity. The second is a new rain index, ...
Tópico(s): Fire effects on ecosystems
2010 - Copernicus Publications | Advances in geosciences
The zebrafish pineal gland is a photoreceptive organ containing an intrinsic central circadian oscillator, which drives daily rhythms of gene expression and the melatonin hormonal signal. Here we investigated the effect of light, given at early developmental stages before pineal gland formation, on the pineal circadian oscillator. Embryos that were exposed to light at 0–6, 10–13, or 10–16 h after fertilization exhibited clock-controlled rhythms of arylalkylamine- N -acetyltransferase ( zfaanat2 ) mRNA ...
Tópico(s): Spaceflight effects on biology
2006 - National Academy of Sciences | Proceedings of the National Academy of Sciences
In zebrafish, pineal arylalkylamine‐N‐acetyltransferase (zfaanat2) mRNA expression begins at 22 h post‐fertilization (hpf), and the clock‐controlled rhythm of its transcript begins on the third day of development. Here we describe the role of light and of the clock gene, period2 (zper2) in the development of this rhythm. In 1‐day‐old zebrafish embryos, zper2 expression is transiently up‐regulated by light in the pineal gland and, to a lesser extent, in other areas of the brain. Expression of zper2 ...
Tópico(s): Neurobiology and Insect Physiology Research
2006 - Taylor & Francis | Chronobiology International
Assaf Zinger, Lilach Koren, Omer Adir, Maria Poley, Mohammed Alyan, Zvi Yaari, Nadav Noor, Nitzan Krinsky, Assaf Simon, Hadas Gibori, Majd Krayem, Yelena Mumblat, Shira Kasten, Sivan Ofir, Eran Fridman, Neta Milman, Michael M. Lübtow, Lior Liba, Jeny Shklover, Janna Shainsky‐Roitman, Yoav Binenbaum, Dov Hershkovitz, Ziv Gil, Tal Dvir, Robert Luxenhofer, Ronit Satchi‐Fainaro, Avi Schroeder,
Overexpressed extracellular matrix (ECM) in pancreatic ductal adenocarcinoma (PDAC) limits drug penetration into the tumor and is associated with poor prognosis. Here, we demonstrate that a pretreatment based on a proteolytic-enzyme nanoparticle system disassembles the dense PDAC collagen stroma and increases drug penetration into the pancreatic tumor. More specifically, the collagozome, a 100 nm liposome encapsulating collagenase, was rationally designed to protect the collagenase from premature ...
Tópico(s): Pancreatitis Pathology and Treatment
2019 - American Chemical Society | ACS Nano
Ya. Z. Slutsker, V. E. Semenov, Ya. E. Krasik, M. A. Ryzhkov, J. Felsteiner, Yoav Binenbaum, Ziv Gil, Ronit Shtrichman, Jacob T. Cohen,
We present an analytical model of cold atmospheric plasma formed by a dielectric barrier discharge (DBD), which is based on the lumped and distributed elements of an equivalent electric circuit of this plasma. This model is applicable for a wide range of frequencies and amplitudes of the applied voltage pulses, no matter whether or not the generated plasma plume interacts with a target. The model allows quantitative estimation of the plasma plume length and the energy delivered to the plasma. Also, ...
Tópico(s): Electrohydrodynamics and Fluid Dynamics
2017 - American Institute of Physics | Physics of Plasmas
Gal Ziv, Yoav Meckel, Ronnie Lidor, Arie Rotstein,
The purpose of this study was to examine the influence of external focus of attention and internal focus of attention instructions on physiological responses in experienced adolescent basketball players (n = 17; mean age = 15.1±0.6 years).After a 10-min warm-up at a running velocity equal to 60% of the heart rate reserve, participants ran on a treadmill under two 10-min conditions: (a) internal focus instructions -focusing on the legs and running motion, and (b) external focus instructions -focusing on a ...
Tópico(s): Cardiovascular and exercise physiology
2012 - University of Alicante | Journal of Human Sport and Exercise
Michal Ganot, Yoav Yair, Colin Price, Baruch Ziv, Yosef Sherez, Eran Greenberg, Adam D. Devir, Roy Yaniv,
During the winter of 2005–6, optical ground‐based observations were performed to detect transient luminous events (TLEs) above winter thunderstorms in the vicinity of Israel and the eastern coastline of the Mediterranean Sea. Two sites were used: the Tel Aviv University (TAU) campus in Tel‐Aviv (32.5N, 34.5E) and the Wise astronomical observatory in the Negev desert (30.6N, 34.76E). We also conducted ELF and VLF electromagnetic measurements from the TAU array in southern Israel. In 4 different winter ...
Tópico(s): Plant responses to elevated CO2
2007 - American Geophysical Union | Geophysical Research Letters
Yoav Bashan, Hanna Levanony, Orit Ziv-Vecht,
Following inoculation of wheat grown under field conditions with Azospirillum brasilense Cd, the bacterial population in the plants rhizosphere during the winter growth season was monitored. Seven field experiments were conducted during 3 years, in five soil types, and the bacteria were counted using two different methods of enumeration. Azospirillum brasilense Cd were detected in the wheat fields up to 105 days after inoculation at a level of 10 4 to 5 × 10 5 cells/g fresh weight roots, with a very ...
Tópico(s): Agronomic Practices and Intercropping Systems
1987 - Canadian Science Publishing | Canadian Journal of Microbiology
Liron Sheintuch, Nitzan Geva, Hadas Baumer, Yoav Rechavi, Alon Rubin, Yaniv Ziv,
Hippocampal place cells selectively fire when an animal traverses a particular location and are considered a neural substrate of spatial memory. Place cells were shown to change their activity patterns (remap) across different spatial contexts but to maintain their spatial tuning in a fixed familiar context. Here, we show that mouse hippocampal neurons can globally remap, forming multiple distinct representations (maps) of the same familiar environment, without any apparent changes in sensory input ...
Tópico(s): Zebrafish Biomedical Research Applications
2020 - Elsevier BV | Current Biology
Alon Rubin, Liron Sheintuch, Noa Brande-Eilat, Or Pinchasof, Yoav Rechavi, Nitzan Geva, Yaniv Ziv,
Abstract Measuring neuronal tuning curves has been instrumental for many discoveries in neuroscience but requires a priori assumptions regarding the identity of the encoded variables. We applied unsupervised learning to large-scale neuronal recordings in behaving mice from circuits involved in spatial cognition and uncovered a highly-organized internal structure of ensemble activity patterns. This emergent structure allowed defining for each neuron an ‘internal tuning-curve’ that characterizes its ...
Tópico(s): Neuroscience and Neuropharmacology Research
2019 - Nature Portfolio | Nature Communications
Yoav Binenbaum, G. Ben-David, Ziv Gil, Ya. Z. Slutsker, M. A. Ryzhkov, J. Felsteiner, Ya. E. Krasik, Jacob T. Cohen,
Cold Atmospheric Plasma Jet (CAPJ), with ion temperature close to room temperature, has tremendous potential in biomedical engineering, and can potentially offer a therapeutic option that allows cancer cell elimination without damaging healthy tissue. We developed a hand-held flexible device for the delivery of CAPJ to the treatment site, with a modified high-frequency pulse generator operating at a RMS voltage of <1.2 kV and gas flow in the range 0.3-3 l/min. The aims of our study were to characterize ...
Tópico(s): Fluid Dynamics and Heat Transfer
2017 - Public Library of Science | PLoS ONE
Galit Aviram, Eugene Soikher, Achiude Bendet, Hezzy Shmueli, Tomer Ziv‐Baran, Yoav Amitai, Limor Friedensohn, Shlomo Berliner, Ahuava Meilik, Yan Topilsky,
Preliminary reports suggest that a small left atrium (LA) is associated with severe acute pulmonary embolism (PE). This study used data derived from volumetric analyses of computed tomographic pulmonary angiography (CTPA) to investigate whether a reduced LA volume can predict adverse outcome in a large series of patients with acute PE.We retrospectively analyzed 756 consecutive patients who received a diagnosis of acute PE by nongated CTPA between January 2007 and December 2010. Each CTPA was investigated ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2015 - Elsevier BV | CHEST Journal
Yoav Binenbaum, Shorook Na’ara, Ziv Gil,
Pancreatic ductal adenocarcinoma (PDA) ranks fourth among cancer related deaths. The disappointing 5-year survival rate of below 5% stems from drug resistance to all known therapies, as well as from disease presentation at a late stage when PDA is already metastatic. Gemcitabine has been the cornerstone of PDA treatment in all stages of the disease for the last two decades, but gemcitabine resistance develops within weeks of chemotherapy initiation. From a mechanistic perspective, gemcitabine resistance ...
Tópico(s): Cancer Genomics and Diagnostics
2015 - Elsevier BV | Drug Resistance Updates
Ehud Zigmond, Ami Ben Ya’acov, Hyunbeom Lee, Yoav Lichtenstein, Zvi Shalev, Yoav Smith, Lidya Zolotarov, Ehud Ziv, Rony Kalman, Hoang V. Le, Hejun Lu, Richard B. Silverman, Yaron Ilan,
Hepatocellular carcinoma is the second leading cause of cancer death worldwide. DNA microarray analysis identified the ornithine aminotransferase (OAT) gene as a prominent gene overexpressed in hepatocellular carcinoma (HCC) from Psammomys obesus. In vitro studies demonstrated inactivation of OAT by gabaculine (1), a neurotoxic natural product, which suppressed in vitro proliferation of two HCC cell lines. Alpha-fetoprotein (AFP) secretion, a biomarker for HCC, was suppressed by gabaculine in both cell ...
Tópico(s): Amino Acid Enzymes and Metabolism
2015 - American Chemical Society | ACS Medicinal Chemistry Letters
Ayelet Shabtay‐Orbach, Moran Amit, Yoav Binenbaum, Shorook Na’ara, Ziv Gil,
It was suggested that the brain microenvironment plays a role in glioma progression. Here we investigate the mechanism by which astrocytes which are abundant in glioma tumors, promote cancer cell invasion. In this study, we evaluated the effects of astrocytes on glioma biology both in vitro and in vivo and determined the downstream paracrine effect of glial-derived neurotrophic factor (GDNF) on tumor invasion. Astrocytes-conditioned media (ACM) significantly increased human and murine glioma cells ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2014 - Wiley | International Journal of Cancer
Moran Amit, Yoav Binenbaum, Jacob T. Cohen, Ziv Gil,
BACKGROUND: This single-blinded, prospective, randomized controlled trial compared the efficacy and safety of an oxidized cellulose patch (Surgicel [Johnson and Johnson]) with conventional procedures for achieving hemostasis in thyroid surgery. STUDY DESIGN: The study included 190 patients scheduled for thyroidectomy. Patients were randomized into 1 conventionally treated (ligatures and bipolar electrocautery) group (n = 92) and a second group, which additionally received Surgicel (n = 98). RESULTS: The ...
Tópico(s): Airway Management and Intubation Techniques
2013 - Lippincott Williams & Wilkins | Journal of the American College of Surgeons
Produção Nacional
Revisado por pares
Moran Amit, Tzu‐Chen Yen, Chun‐Ta Liao, Pankaj Chaturvedi, Jai Prakash Agarwal, Luiz Paulo Kowalski, Ardalan Ebrahimi, Jonathan R. Clark, Matthias Kreppel, Joachim E. Zöller, Eran Fridman, Villaret A. Bolzoni, Jatin P. Shah, Yoav Binenbaum, Snehal G. Patel, Ziv Gil,
An association between the survival of patients with oral cavity squamous cell carcinoma (OCSCC) and advancements in diagnosis and therapy has not been established.This was a retrospective, longitudinal, international, population-based study of 2738 patients who underwent resection of OCSCC during 2 different decades. Characteristics of patients from 7 international cancer centers who received treatment between 1990 and 2000 (group A; n = 735) were compared with patients who received treatment between ...
Tópico(s): Salivary Gland Tumors Diagnosis and Treatment
2013 - Wiley | Cancer
Noam Weizman, Yakov Krelin, Ayelet Shabtay‐Orbach, Moran Amit, Yoav Binenbaum, Richard J. Wong, Ziv Gil,
Resistance to pharmacologic agents used in chemotherapy is common in most human carcinomas, including pancreatic ductal adenocarcinoma (PDA), which is resistant to almost all drugs, including gemcitabine, a nucleoside analog used as a first-line treatment. Poor survival rates of PDA patients have, therefore, not changed much over 4 decades. Recent data indicated that tumor-associated macrophages (TAMs), which are abundant in the microenvironment of several tumors, including PDA, secrete pro-tumorigenic ...
Tópico(s): Phagocytosis and Immune Regulation
2013 - Springer Nature | Oncogene