Youji Miyamoto, Kunio Ishikawa, Masaaki Takechi, Taketomo Toh, Yuki Yoshida, Masaru Nagayama, Masayuki Kon, Kenzo Asaoka,
... JapanSearch for more papers by this authorYuki Yoshida, Yuki Yoshida First Department of Oral and Maxillofacial Surgery, School ... JapanSearch for more papers by this authorYuki Yoshida, Yuki Yoshida First Department of Oral and Maxillofacial Surgery, School ...
Tópico(s): Dental materials and restorations
1997 - Wiley | Journal of Biomedical Materials Research
Mathys Grapotte, Manu Saraswat, Chloé Bessière, Christophe Menichelli, Jordan A. Ramilowski, Jessica Severin, Yoshihide Hayashizaki, Masayoshi Itoh, Michihira Tagami, Mitsuyoshi Murata, Miki Kojima-Ishiyama, Shohei Noma, Shuhei Noguchi, Takeya Kasukawa, Akira Hasegawa, Harukazu Suzuki, Hiromi Nishiyori-Sueki, Martin C. Frith, Imad Abugessaisa, Stuart Aitken, Bronwen L. Aken, Intikhab Alam, Tanvir Alam, Rami Alasiri, Ahmad M. N. Alhendi, Hamid Alinejad‐Rokny, Mariano J. Alvarez, Robin Andersson, Takahiro Arakawa, Marito Araki, Taly Arbel, John Archer, Alan Archibald, Peter Arner, Peter Arner, Kiyoshi Asai, Haitham Ashoor, Gaby Åström, Magda Babina, J. Kenneth Baillie, Vladimir B. Bajić, Archana Bajpai, Sarah Baker, Richard M. Baldarelli, Adam Balic, Mukesh Bansal, Arsen O. Batagov, Serafim Batzoglou, Anthony G Beckhouse, Antonio Paolo Beltrami, Carlo Alberto Beltrami, Nicolas Bertin, Sharmodeep Bhattacharya, Peter J. Bickel, Judith A. Blake, Mathieu Blanchette, Beatrice Bodega, Alessandro Bonetti, Hidemasa Bono, Jette Bornholdt, Michael Bttcher, Salim Bougouffa, Mette Boyd, Jérémie Breda, Frank Brombacher, James B. Brown, Carol J. Bult, A. Maxwell Burroughs, David W. Burt, Annika Busch, Giulia Caglio, Andrea Califano, Christopher JF Cameron, Carlo Vittorio Cannistraci, Alessandra Carbone, Ailsa J Carlisle, Piero Carninci, Kim W. Carter, Daniela Cesselli, Jen-Chien Chang, Julie C. Chen, Yun Chen, Marco Chierici, John Christodoulou, Yari Ciani, Emily L. Clark, Mehmet Coskun, Maria Dalby, Emiliano Dalla, Carsten O. Daub, Carrie Davis, Michiel de Hoon, Derek de Rie, Elena Denisenko, Bart Deplancke, Michael Detmar, Ruslan Deviatiiarov, Diego di Bernardo, Alexander D. Diehl, Lothar C. Dieterich, Emmanuel Dimont, Sarah Djebali, Taeko Dohi, Jose Dostie, Finn Drabløs, Albert S.B. Edge, Matthias Edinger, Anna Ehrlund, Karl Ekwall, Arne Elofsson, Mitsuhiro Endoh, Hideki Enomoto, Saaya Enomoto, Mohammad Ali Faghihi, Michela Fagiolini, Mary C. Farach‐Carson, Geoffrey J. Faulkner, Alexander V. Favorov, Ana Miguel Fernandes, Carmelo Ferrai, Alistair R. R. Forrest, Lesley M. Forrester, Mattias Forsberg, Alexandre Fort, Margherita Francescatto, Tom C. Freeman, Martin C. Frith, Shinji Fukuda, Manabu Funayama, Cesare Furlanello, Masaaki Furuno, Chikara Furusawa, Hui Gao, Iveta Gažová, Claudia Gebhard, Florian Geier, Teunis B. H. Geijtenbeek, Samik Ghosh, Yanal Ghosheh, T Gingeras, Takashi Gojobori, Tatyana Goldberg, Dan Goldowitz, Julian Gough, Dario Greco, Andreas Gruber, Sven Guhl, Roderic Guigó, Reto Guler, Oleg Gusev, Stefano Gustincich, Thomas J Ha, Vanja Haberle, Paul Hale, Bjrn M. Hallstrom, Michiaki Hamada, Lusy Handoko, Mitsuko Hara, Matthias Harbers, Jennifer Harrow, Jayson Harshbarger, Takeshi Hase, Akira Hasegawa, Kosuke Hashimoto, Taku Hatano, Nobutaka Hattori, Ryuhei Hayashi, Yoshihide Hayashizaki, Meenhard Herlyn, Peter Heutink, Yoshihide Hayashizaki, Kelly J Hitchens, Shannon Ho Sui, Peter A.C. ‘t Hoen, Chung-Chau Hon, Fumi Hori, Masafumi Horie, Katsuhisa Horimoto, Paul Horton, Rui Hou, Edward Huang, Yi Huang, Richard Hugues, David Hume, Hans Ienasescu, Kei Iida, Tomokatsu Ikawa, Toshimichi Ikemura, Kazuho Ikeo, Norihiko Inoue, Yuri Ishizu, Yosuke Ito, Masayoshi Itoh, Anna V. Ivshina, Boris R. Janković, Piroon Jenjaroenpun, Rory Johnson, Mette Jørgensen, Hadi Jorjani, Anagha Joshi, Giuseppe Jurman, Bogumił Kaczkowski, Chieko Kai, Kaoru Kaida, Kazuhiro Kajiyama, Rajaram Kaliyaperumal, Eli Kaminuma, Takashi Kanaya, Hiroshi Kaneda, Philip Kapranov, Artem S. Kasianov, Takeya Kasukawa, Toshiaki Katayama, Sachi Kato, Shuji Kawaguchi, Jun Kawai, Hideya Kawaji, Hiroshi Kawamoto, Yuki I. Kawamura, Satoshi Kawasaki, Tsugumi Kawashima, Judith Kempfle, Tony Kenna, Juha Kere, Levon M. Khachigian, Hisanori Kiryu, Mami Kishima, Hiroyuki Kitajima, Toshio Kitamura, Hiroaki Kitano, Enio Klarić, Kjetil Klepper, S. Peter Klinken, Edda Kloppmann, Alan J. Knox, Yuichi Kodama, Yasushi Kogo, Miki Kojima, Soichi Kojima, Norio Komatsu, Hiromitsu Komiyama, Tsukasa Kono, Haruhiko Koseki, Shigeo Koyasu, Anton Kratz, Alexander Kukalev, Ivan V. Kulakovskiy, Anshul Kundaje, Hiroshi Kunikata, Richard Kuo, Tony Kuo, Shigehiro Kuraku, Vladimir A. Kuznetsov, Tae Jun Kwon, Matt Larouche, Timo Lassmann, Andy Law, Kim‐Anh Lê Cao, Charles‐Henri Lecellier, Weon-Ju Lee, Boris Lenhard, Andreas Lennartsson, Kang Li, Ruohan Li, Berit Lilje, Leonard Lipovich, Marina Lizio, Gonzalo López, Shigeyuki Magi, Gloria K. Mak, Vsevolod J. Makeev, Riichiro Manabe, Michiko Mandai, Jessica C. Mar, Kazuichi Maruyama, Taeko Maruyama, Elizabeth A. Mason, Anthony Mathelier, Hideo Matsuda, Yulia A. Medvedeva, Terrence F. Meehan, Niklas Mejhert, Alison Meynert, Norihisa Mikami, Akiko Minoda, Hisashi Miura, Yohei Miyagi, Atsushi Miyawaki, Yosuke Mizuno, Hiromasa Morikawa, Mitsuru Morimoto, M. Morioka, Soji Morishita, Kazuyo Moro, Efthymios Motakis, Hozumi Motohashi,
Abstract Using the Cap Analysis of Gene Expression (CAGE) technology, the FANTOM5 consortium provided one of the most comprehensive maps of transcription start sites (TSSs) in several species. Strikingly, ~72% of them could not be assigned to a specific gene and initiate at unconventional regions, outside promoters or enhancers. Here, we probe these unassigned TSSs and show that, in all species studied, a significant fraction of CAGE peaks initiate at microsatellites, also called short tandem repeats ( ...
Nature Portfolio

Unai Pascual, Patricia Balvanera, Christopher B. Anderson, Rebecca Chaplin‐Kramer, Mike Christie, David González-Jiménez, Adrián Martín, Christopher M. Raymond, Mette Termansen, Arild Vatn, Simone Athayde, Brigitte Baptiste, David N. Barton, Sander Jacobs, Eszter Kelemen, Ritesh Kumar, Elena Lazos, Tuyeni H. Mwampamba, Barbara Nakangu, Patrick O’Farrell, Suneetha M. Subramanian, Meine van Noordwijk, SoEun Ahn, Sacha Amaruzaman, Ariane Amin, Paola Arias‐Arévalo, Gabriela Arroyo-Robles, Mariana Cantú-Fernández, Antonio Arjona Castro, Victoria Contreras, Alta De Vos, Nicolas Dendoncker, Stefanie Engel, Uta Eser, Daniel P. Faith, Anna Filyushkina, Houda Ghazi, Erik Gómez‐Baggethun, Rachelle K. Gould, Louise Guibrunet, Haripriya Gundimeda, Thomas P. Hahn, Zuzana V. Harmáčková, Marcello Hernández‐Blanco, Andra‐Ioana Horcea‐Milcu, Mariaelena Huambachano, Natalia Lutti Hummel Wicher, Cem İskender Aydın, Mine Işlar, Ann‐Kathrin Koessler, Jasper O. Kenter, Marina Kosmus, Heera Lee, Beria Leimona, Sharachchandra Lélé, Dominic Lenzi, Bosco Lliso, Lelani Mannetti, Juliana Merçon, Ana Sofía Monroy‐Sais, Nibedita Mukherjee, Barbara Muraca, Roldán Muradian, Ranjini Murali, Sara Nelson, Gabriel R. Nemogá, Jonas Ngouhouo Poufoun, Aidin Niamir, Emmanuel Nuesiri, Tobias Ochieng Nyumba, Begüm Özkaynak, Ignacio Palomo, Ram Pandit, Agnieszka Pawłowska-Mainville, Luciana Porter‐Bolland, Martin F. Quaas, Julian Rode, Ricardo Rozzi, Sonya Sachdeva, Aibek Samakov, Marije Schaafsma, Nadia Sitas, Paula Ungar, Evonne Yiu, Yuki Yoshida, Egleé L. Zent,
Abstract Twenty-five years since foundational publications on valuing ecosystem services for human well-being 1,2 , addressing the global biodiversity crisis 3 still implies confronting barriers to incorporating nature’s diverse values into decision-making. These barriers include powerful interests supported by current norms and legal rules such as property rights, which determine whose values and which values of nature are acted on. A better understanding of how and why nature is (under)valued is ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2023 - Nature Portfolio | Nature
Kanako Miyano, Minori Ikehata, Kaori Ohshima, Yuki Yoshida, Yasuhiro Nose, Sei-ichi Yoshihara, Katsuyuki Oki, Seiji Shiraishi, Miaki Uzu, Miki Nonaka, Yoshikazu Higami, Yasuhito Uezono,
Mesenchymal stem cells (MSCs), which are isolated from adipose tissue (AD-MSCs), umbilical cord (UC-MSCs), or bone marrow, have therapeutic potential including anti-inflammatory and immunomodulatory activities. It was recently reported that MSCs are also effective as a therapeutic treatment for neuropathic pain, although the underlying mechanisms have yet to be resolved. Therefore, in this study, we investigated the effects of human AD- and UC-MSCs on neuropathic pain and its mechanisms using rat models ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2022 - Public Library of Science | PLoS ONE
Yuki Yoshida, Tadashi Satoh, Chise Ota, Sae Tanaka, Daiki D. Horikawa, Masaru Tomita, Koichi Kato, Kazuharu Arakawa,
Tardigrades are microscopic animals that are capable of tolerating extreme environments by entering a desiccated state of suspended animation known as anhydrobiosis. While antioxidative stress proteins, antiapoptotic pathways and tardigrade-specific intrinsically disordered proteins have been implicated in the anhydrobiotic machinery, conservation of these mechanisms is not universal within the phylum Tardigrada, suggesting the existence of overlooked components.Here, we show that a novel Mn-dependent ...
Tópico(s): Spaceflight effects on biology
2022 - BioMed Central | BMC Genomics
Naohiro Itoh, Hirokazu Mishima, Yuki Yoshida, Manami Yoshida, Hiroyuki Oka, Ko Matsudaira,
Background Artificial intelligence–assisted interactive health promotion systems are useful tools for the management of musculoskeletal conditions. Objective This study aimed to explore the effects of web-based video patient education and strengthening exercise therapy, using a mobile messaging app, on work productivity and pain in patients with chronic low back pain (CLBP) receiving pharmacological treatment. Methods Patients with CLBP were randomly allocated to either the exercise group, who received ...
Tópico(s): Stroke Rehabilitation and Recovery
2022 - JMIR Publications | JMIR mhealth and uhealth
Paikun Zhu, Yuki Yoshida, Atsushi Kanno, Ken-ichi Kitayama,
High-speed intensity-modulation direct-detection (IM/DD) fiber optical transmission system is of great interest to the applications of datacenter interconnects (DCI) as well as edge/access networks. However, when the fiber reach is beyond 40 km such as ER or ZR, the power fading induced by chromatic dispersion (CD) in C-band, S-band and even edge-wavelengths of O-band becomes a severe issue with the ever-increasing signal data rate. In this work, we focus on an ultra-low complexity joint optical-electrical ...
Tópico(s): Advanced Photonic Communication Systems
2022 - Institute of Electrical and Electronics Engineers | Journal of Lightwave Technology
Yuki Yoshida, Hirotaka Matsuda, Kensuke Fukushi, Kazuhiko Takeuchi, Ryugo Watanabe,
Abstract Communities in socio-ecological production landscapes and seascapes are aging and depopulating. While longstanding interdependence of humans and nature in such areas holds crucial hints for sustainable development, they continue to be undervalued by existing economic frameworks. We suspect omission of non-material nature’s contributions to people (NCPs) as a possible reason for this undervaluation and focus on the intangible aspects of human–nature relationships: people’s direct and emotional ...
Tópico(s): Land Use and Ecosystem Services
2022 - Springer Science+Business Media | Sustainability Science
Nurul Widiastuti, Irmariza Shafitri Caralin, Alvin Rahmad Widyanto, Rika Wijiyanti, Triyanda Gunawan, Zulhairun Abdul Karim, Mikihiro Nomura, Yuki Yoshida,
Recently, natural gas (mostly methane) is frequently used as fuel, while hydrogen is a promising renewable energy source. However, each gas produced contains impurity gases. As a result, membrane separation is required. The mixed matrix membrane (MMM) is a promising membrane. The huge surface area and well-defined pore structure of zeolite templated carbon (ZTC)-based MMM allow for effective separation. However, the interfacial vacuum in MMM is difficult to avoid, contributing to poor separation performance. ...
Tópico(s): Graphene research and applications
2022 - Royal Society | Royal Society Open Science
Yuya Sugie, Yuki Yoshida, Normann Mertig, Takashi Takemoto, Hiroshi Teramoto, Atsuyoshi Nakamura, Ichigaku Takigawa, Shin-ichi Minato, Masanao Yamaoka, Tamiki Komatsuzaki,
Minor-embedding heuristics have become an indispensable tool for compiling problems in quadratically unconstrained binary optimization (QUBO) into the hardware graphs of quantum and CMOS annealing processors. While recent embedding heuristics have been developed for annealers of moderate size (about 2000 nodes), the size of the latest CMOS annealing processor (with 102,400 nodes) poses entirely new demands on the embedding heuristic. This raises the question, if recent embedding heuristics can maintain ...
Tópico(s): Stochastic Gradient Optimization Techniques
2021 - Springer Science+Business Media | Soft Computing
Ken Mishina, Shingo Sato, Yuki Yoshida, Daisuke Hisano, Akihiro Maruta,
Optical eigenvalue communication is a promising technique for overcoming the Kerr nonlinear limit in optical communication systems. The optical eigenvalue associated with the nonlinear Schrödinger equation remains invariant during fiber-based nonlinear dispersive transmission. However, practical applications involving use of such systems are limited by the occurrence of fiber loss and amplified noise that induce eigenvalue distortion. Thus, several time-domain neural-network-based approaches have ...
Tópico(s): Advanced Photonic Communication Systems
2021 - Institute of Electrical and Electronics Engineers | Journal of Lightwave Technology
Nobuaki Kono, Rintaro Ohtoshi, Ali D. Malay, Masaru Mori, Hiroyasu Masunaga, Yuki Yoshida, Hiroyuki Nakamura, Keiji Numata, Kazuharu Arakawa,
Spider silk is a protein-based material whose toughness suggests possible novel applications. A particularly fascinating example of silk toughness is provided by Darwin's bark spider ( Caerostris darwini ) found in Madagascar. This spider produces extraordinarily tough silk, with an average toughness of 350 MJ m −1 and over 50% extensibility, and can build river-bridging webs with a size of 2.8 m 2 . Recent studies have suggested that specific spidroins expressed in C. darwini are responsible for the mechanical ...
Tópico(s): Antimicrobial Peptides and Activities
2021 - Royal Society | Open Biology
Nobuaki Kono, Hiroyuki Nakamura, Masaru Mori, Yuki Yoshida, Rintaro Ohtoshi, Ali D. Malay, Daniel A. Pedrazzoli Moran, Masaru Tomita, Keiji Numata, Kazuharu Arakawa,
Significance Artificial synthesis of spider silk has been actively pursued. However, until now, the natural mechanical properties of spider silk have been largely unreproducible. We thoroughly investigated the genomes and transcripts of four related species of orb-weaver spiders as well as the proteins in their silk threads. Then, in addition to spidroin, we found several low-molecular-weight proteins in common. Interestingly, the low-molecular-weight protein component of spider dragline silk doubled ...
Tópico(s): Antimicrobial Peptides and Activities
2021 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Sunao Mikura, Takeshi Saraya, Yuki Yoshida, Miku Oda, Manabu Ishida, Kojiro Honda, Keitaro Nakamoto, Masaki Tamura, Saori Takata, Hiroaki Shimoyamada, Masachika Fujiwara, Haruyuki Ishii,
A 45-year-old man with allergic bronchopulmonary aspergillosis (ABPA) was treated with oral prednisolone (PSL) (30 mg/day), inhaled corticosteroids, and long-acting beta2-agonists. After confirmation of a PSL-dependent status (8 mg/day), subcutaneous injection with anti-interleukin (IL)-5 antibody (mepolizumab, 100 mg/month) was performed, and the PSL dose was tapered to 5 mg/day. However, ABPA recurred and proved refractory to oral itraconazole (200 mg/day). Alternative subcutaneous injection therapy ...
Tópico(s): Respiratory and Cough-Related Research
2021 - The Japanese Society of Internal Medicine | Internal Medicine
Yuki Yoshida, Masakazu Honma, Yasuaki Kimura, Hiroshi Abe,
Abstract Acquired immunodeficiency syndrome (AIDS) is caused by infection with the human immunodeficiency virus (HIV). Although treatments against HIV infection are available, AIDS remains a serious disease that causes many deaths annually. Although a variety of anti‐HIV drugs have been synthesized and marketed to treat HIV‐infected patients, nucleoside analogue reverse transcriptase inhibitors (NRTIs), which mimic nucleosides, are used extensively and remain a subject of interest to medicinal chemists. ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2020 - Wiley | ChemMedChem
Yoshihiro Mori, Yuki Yoshida, Ayano Satoh, Hisao Moriya,
Abstract Protein overexpression sometimes causes cellular defects, although the underlying mechanism is still unknown. A protein’s expression limit, which triggers cellular defects, is a useful indication of the underlying mechanism. In this study, we developed an experimental method of estimating the expression limits of target proteins in the human embryonic kidney cell line HEK293 by measuring the proteins’ expression levels in cells that survived after the high-copy introduction of plasmid DNA ...
Tópico(s): Fungal and yeast genetics research
2020 - Nature Portfolio | Scientific Reports
Paikun Zhu, Yuki Yoshida, Ken-ichi Kitayama,
Wired-wireless convergence technology such as radio-over-fiber (RoF) is regarded as a promising candidate to deliver broadband wireless data from/to edge cloud to/from antenna sites, a notable example being the fronthaul (FH) in centralized/cloud radio access network (C-RAN). In 5G and beyond, the latency, bandwidth and fidelity requirements on FH pose great challenges to the RoF schemes. In this article, we focus on analog-to-digital-compression RoF (ADX-RoF) scheme based on low-latency MIMO data compression, ...
Tópico(s): Optical Network Technologies
2020 - Institute of Electrical and Electronics Engineers | Journal of Lightwave Technology
Kazunobu Kojima, Yuki Yoshida, Masaki Shiraiwa, Yoshinari Awaji, Atsushi Kanno, Naokatsu Yamamoto, Akira Hirano, Yosuke Nagasawa, Masamichi Ippommatsu, Shigefusa F. Chichibu,
The origin of the fast modulation characteristics of deep ultraviolet (DUV) AlGaN light-emitting diodes (LEDs) grown on AlN/sapphire templates with vicinal off-angles is reported by employing time-resolved electroluminescence (EL) and micro-imaging experiments. The LEDs have recently demonstrated Gbps-class optical wireless communication (OWC) under both room-lighting and direct-sun. The frequency response (f3dB) of the LED reached 184 MHz, which is far beyond expectations by considering the size of ...
Tópico(s): Plasma Diagnostics and Applications
2020 - American Institute of Physics | Applied Physics Letters
Michael G. Ison, Simon Portsmouth, Yuki Yoshida, Takao Shishido, Melissa Mitchener, Kenji J. Tsuchiya, Takeki Uehara, Frederick G. Hayden,
Tópico(s): RNA and protein synthesis mechanisms
2020 - Elsevier BV | The Lancet Infectious Diseases
Shigeru Aoyama, Issam Ismail, Yong Tae Park, Yuki Yoshida, Christopher W. Macosko, Toshiaki Ougizawa,
Graphene was modified with trimellitic anhydride groups, and its polyethylene-terephthalate-based (PET-based) nanocomposites were prepared by melt-mixing. Percolation thresholds observed from changes to the electrical conductivity and storage moduli of nanocomposite melts suggest that the dispersion levels of unmodified graphene and those of modified graphene in PET matrix were the same. An enhancement of G′ and unexpectedly higher [η] for modified graphene at low concentration suggest that PET chains ...
Tópico(s): Polymer crystallization and properties
2018 - American Chemical Society | ACS Applied Nano Materials
Michael G. Ison, Simon Portsmouth, Yuki Yoshida, Takao Shishido, Frederick G. Hayden, Takeki Uehara,
Abstract Background Baloxavir marboxil (BXM), an oral selective cap-dependent endonuclease inhibitor, is effective and safe for treating acute influenza in otherwise healthy patients. Method We conducted an international, randomized, double-blind, placebo (PLC)- and oseltamivir (Os)-controlled treatment study in patients at higher risk (HR) of influenza complications. Inclusion criteria included age ≥12 years, fever + influenza symptoms of ≤48 hours duration, and presence of at least 1 HR factor adapted ...
Tópico(s): Tuberculosis Research and Epidemiology
2018 - Oxford University Press | Open Forum Infectious Diseases
Yoshiyuki Meguro, Kanako Miyano, Shigeto Hirayama, Yuki Yoshida, Naoto Ishibashi, Takumi Ogino, Yuriko Fujii, Sei Manabe, Moeko Eto, Miki Nonaka, H. Fujii, Yoichi Ueta, Minoru Narita, Naohiro Sata, Toshihiko Yada, Yasuhito Uezono,
Oxytocin (OT) is a 9-amine neuropeptide that plays an essential role in mammalian labor, lactation, maternal bonding, and social affiliation. OT has been reported to exert an analgesic effect in both humans and animals, and the results of certain animal experiments have shown that the analgesic effect of OT is partially blocked by opioid receptor antagonists. To investigate the relationship between OT and μ opioid receptor (MOR), we evaluated how OT affects MOR in vitro by performing an electrical ...
Tópico(s): Receptor Mechanisms and Signaling
2018 - Elsevier BV | Journal of Pharmacological Sciences
Шун-ичи Амари, Tomoko Ozeki, Ryo Karakida, Yuki Yoshida, Masato Okada,
The dynamics of supervised learning play a main role in deep learning, which takes place in the parameter space of a multilayer perceptron (MLP). We review the history of supervised stochastic gradient learning, focusing on its singular structure and natural gradient. The parameter space includes singular regions in which parameters are not identifiable. One of our results is a full exploration of the dynamical behaviors of stochastic gradient learning in an elementary singular network. The bad news ...
Tópico(s): Neural dynamics and brain function
2017 - The MIT Press | Neural Computation
Yu Matsuda, Tomohiro Kameya, Yūichi Suzuki, Yuki Yoshida, Yasuhiro Egami, Hiroki Yamaguchi, Tomohide NIIMI,
We have proposed an instant method for painting of pressure- and temperature-sensitive paints (PSP and TSP) using a commercial inkjet printer. This method enables us to finely and separately paint PSP and TSP to prevent them from being mixed and the interaction between PSP and TSP dyes. Moreover, the pressure-sensitivity of inkjet-printed PSP was similar to those of conventional PSPs. We consider this method is promising to measure pressure distribution with temperature variation, because the printing ...
Tópico(s): Photoacoustic and Ultrasonic Imaging
2017 - Elsevier BV | Sensors and Actuators B Chemical
Tobías Plieninger, Ryo Kohsaka, Claudia Bieling, Shizuka Hashimoto, Chiho Kamiyama, Thanasis Kizos, Marianne Penker, Pia Kieninger, Brian J. Shaw, Giles B. Sioen, Yuki Yoshida, Osamu Saitô,
Many Japanese and European landscapes harbor biocultural diversity that has been shaped by human agency over centuries. However, these landscapes are threatened by widespread land abandonment, land-use changes, and urbanization. The aim of this study is to use a "solution scanning" method to identify place-based food networks in Europe and Japan that reinforce linkages between biological and cultural diversity in landscapes. In our analysis of 26 European and 13 Japanese cases, we find that place- ...
Tópico(s): Culinary Culture and Tourism
2017 - Springer Science+Business Media | Sustainability Science
Yuki Yoshida, Courtney G. Flint, Mallory K. Dolan,
US Midwestern farmers are direct actors in managing nitrogen fertilizers and key to remediating water quality problems in agricultural landscapes. As farmers' relationships with nature offer insights into their decisions and conservation practices, surveys and interviews with farmers in two Illinois watersheds explored their human–nature relationship perspectives and linkages to conservation practices. While domineering "Master" perspectives theorized as a cause of human-induced environmental problems ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2017 - Taylor & Francis | Journal of Environmental Planning and Management
Arturo Mayoral, Ricard Vilalta, Raül Muñoz, Ramon Casellas, Ricardo Martínez, Michela Svaluto Moreolo, Josep M. Fàbrega, Alejandro Aguado, Shuangyi Yan, Dimitra Simeonidou, Jose Manuel Gran, Vı́ctor López, Pavel Kaczmarek, R. Szwedowski, Thomas Szyrkowiec, Achim Autenrieth, Norboru Yoshikane, Takehiro Tsuritani, Itsuro Morita, Masaki Shiraiwa, Naoya Wada, Masato Nishihara, Toshiki Tanaka, Tomoo Takahara, Jens C. Rasmussen, Yuki Yoshida, Ken‐ichi Kitayama,
In the context of the fifth generation of mobile technology (5G), multiple technologies will converge into a unified end-to-end system. For this purpose, software defined networking (SDN) is proposed, as the control paradigm will integrate all network segments and heterogeneous optical and wireless network technologies together with massive storage and computing infrastructures. The control orchestration protocol is presented as a unified transport application programming interface solution for joint ...
Tópico(s): Advanced Photonic Communication Systems
2017 - | Journal of Optical Communications and Networking
Yoshitomo Furushima, M. P. Nakada, Yuki Yoshida, Kazuyuki Okada,
Abstract Crystallization and melting kinetics of polyphenylene sulfide (PPS) are determined using fast scanning calorimetry. The temperature dependence of half‐time crystallization of isothermally melt‐crystallized PPS shows a downward convex curve with a minimum at 160 °C. The minimum crystallization half‐time is about 3 s. The analysis of heating rate dependence of the melting temperature reveals a zero‐entropy‐production melting temperature of the sample. The microstructure of the sample, which ...
Tópico(s): Polymer Nanocomposites and Properties
2017 - Wiley | Macromolecular Chemistry and Physics
Tsutomu Fukuda, Teppei Umeki, Keiji Tokushima, Xiang Gao, Yuki Yoshida, Fumito Ishibashi, Yusuke Oku, Naoyuki Nishiya, Yoshimasa Uehara, Masatomo Iwao,
A series of A-ring-modified lamellarin N analogues were designed, synthesized, and evaluated as potential noncovalent inhibitors of the EGFR T790M/L858R mutant, a causal factor in the drug-resistant non-small cell lung cancer. Several water-soluble ammonium- or guanidinium-tethered analogues exhibited good kinase inhibitory activities. The most promising analogue, 14f, displayed an excellent inhibitory profile against the T790M/L858R mutant [IC50 (WT) = 31.8 nM; IC50 (T790M/L858R) = 8.9 nM]. The effects ...
Tópico(s): Ferrocene Chemistry and Applications
2017 - Elsevier BV | Bioorganic & Medicinal Chemistry
Takashi Kogo, Yuki Yoshida, Keisuke Koganei, Hitoshi Matsumoto, Taisuke Watanabe, Jun Ogihara, Takafumi Kasumi,
Rice straw was evaluated as a carbon source for the fungi, Trichoderma reesei and Humicola insolens, to produce enzymes for rice straw hydrolysis. The enzyme activity of T. reesei and H. insolens cultivated in medium containing non-treated rice straw were almost equivalent to the enzyme of T. reesei cultivated in Avicel medium, a form of refined cellulose. The enzyme activity of T. reesei cultivated in medium containing NH4OH-treated rice straw was 4-fold higher than enzyme from cultures grown in ...
Tópico(s): Catalysis for Biomass Conversion
2017 - Elsevier BV | Bioresource Technology