Yuma Takahashi, Suzuki Noriyuki,
Polymorphisms in a population are expected to increase the growth rate and the stability of the population, leading to the expansion of geographical distribution and mitigation of extinction risk of a species. However, the generality of such ecological consequences of colour polymorphism remains uncertain. Here, via a comparative approach, we assessed whether colour polymorphisms influence climatic niche breadth and extinction risk in some groups of damselflies, butterflies and vertebrates. The ...
Tópico(s): Plant and animal studies
2019 - Royal Society | Biology Letters
Yuma Takida, Safumi Suzuki, Masahiro Asada, Hiroaki Minamide,
We present an experimental characterization of frequency- and bias-dependent detector responses in a resonant-tunneling-diode (RTD) terahertz (THz)-wave oscillator. By tuning the incident THz-wave frequency and the bias voltage applied to the RTD device, the origins of detection signals are identified to be two distinct detection modes. One is based on square-law detection near the peak and valley points of the negative differential conductance (NDC) region, with the detection bandwidth determined ...
Tópico(s): Superconducting and THz Device Technology
2020 - American Institute of Physics | Applied Physics Letters
Yuichiro Sugiyama, Yoshiaki Sato, Yuma Kitase, Toshihiko Suzuki, Taiki Kondo, Alkisti Mikrogeorgiou, Asuka Horinouchi, Shoichi Maruyama, Yoshie Shimoyama, Masahiro Tsuji, Satoshi Suzuki, Tokunori Yamamoto, Masahiro Hayakawa,
Perinatal hypoxic-ischemic (HI) brain injury occurs in 1 in 1000 live births and remains the main cause of neurological disability and death in term infants. Cytotherapy has recently emerged as a novel treatment for tissue injury. In particular, mesenchymal stem cells (MSCs) are thought to have therapeutic potential, but little is known about the differences according to their origin. In the current study, we investigated the therapeutic effects and safety of intravenous injection of allogeneic bone ...
Tópico(s): Neonatal Respiratory Health Research
2018 - Frontiers Media | Frontiers in Neurology
Takeo Oku, Masahito Zushi, Yuma Imanishi, Atsushi Suzuki, Kohei Suzuki,
TiO2/CH3NH3PbI3-based photovoltaic devices were fabricated. The microstructures of these devices were investigated by X-ray diffraction, transmission electron microscopy, and their calculations. Structure analysis indicated phase transformation of the perovskite structure from a tetragonal to a cubic system by annealing, which resulted in the improvement of photovoltaic properties of the devices. Effects of a multiple spin-coating method using a mixture solution were also investigated. The result ...
Tópico(s): Quantum Dots Synthesis And Properties
2014 - Institute of Physics | Applied Physics Express
M. Itou, Yuki Orikasa, Yuma Gogyo, Kosuke Suzuki, Hiroshi Sakurai, Yoshiharu Uchimoto, Y. Sakurai,
Results of studies on Compton scattering imaging using synchrotron high-energy X-rays are reported. The technique is applied to a discharging coin cell, and the intensity of Compton scattered X-rays from the inside of the cell has been measured as a function of position and time. The position–time intensity map captures the migration of lithium ions in the positive electrode and reveals the structural change due to the volume expansion of the electrode. This experiment is a critical step in developing ...
Tópico(s): Advanced X-ray Imaging Techniques
2014 - Wiley | Journal of Synchrotron Radiation
Tomoya Kitazume, Zaiju Jiang, Kana Kasai, Yuma Mihara, Mamie Suzuki,
The utility of reusable ionic liquid–proline (or aldolase antibody 38C2) reaction system, proceeding the aldol reactions, is described. Further, obtained α-chloro-β-hydroxy compounds were transformed to the optically active α,β-epoxy carbonyl compounds. The aldolase antibody 38C2–ionic liquid system was able to reuse in Michael additions and the reaction of fluoromethylated imines.
Tópico(s): Ionic liquids properties and applications
2003 - Elsevier BV | Journal of Fluorine Chemistry
Osamu Satō, Yuma Suzuki, Yuki Sato, Shinsuke Sasaki, Tomonori Sonoki,
Apple pomace is one of the major agricultural residues in Aomori prefecture, Japan, and it would be useful to develop effective applications for it. As apple pomace contains easily fermentable sugars such as glucose, fructose and sucrose, it can be used as a feedstock for the fermentation of fuels and chemicals. We previously isolated a new hydrogen-producing bacterium, Clostridium beijerinckii HU-1, which could produce H2 at a production rate of 14.5 mmol of H2/L/h in a fed-batch culture at 37 ° ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2014 - Elsevier BV | Journal of Bioscience and Bioengineering
Yuma Kudo, Hiroyuki Suzuki, Tomohiro Tanaka, Mika K. Kaneko, Yukinari Kato,
Pancreatic cancer exhibits a poor prognosis due to the lack of early diagnostic biomarkers and the resistance to conventional chemotherapy. CD44 has been known as a cancer stem cell marker and plays tumor promotion and drug resistance roles in various cancers. In particular, the splicing variants are overexpressed in many carcinomas and play essential roles in the cancer stemness, invasiveness or metastasis, and resistance to treatments. Therefore, the understanding of each CD44 variant’s (CD44v) ...
Tópico(s): Proteoglycans and glycosaminoglycans research
2023 - Multidisciplinary Digital Publishing Institute | Antibodies
Norio Suzuki, Yuma Iwamura, Taku Nakai, Koichiro Kato, Akihito Otsuki, Akira Uruno, Daisuke Saigusa, Keiko Taguchi, Mikiko Suzuki, Ritsuko Shimizu, Akane Yumoto, Risa Okada, Masaki Shirakawa, Dai Shiba, Satoru Takahashi, Takafumi Suzuki, Masayuki Yamamoto,
Space travel burdens health by imposing considerable environmental stress associated with radioactivity and microgravity. In particular, gravity change predominantly impacts blood pressure and bone homeostasis, both of which are controlled mainly by the kidneys. Nuclear factor erythroid-2-related transcription factor 2 (Nrf2) plays essential roles in protecting the kidneys from various environmental stresses and injuries. To elucidate the effects of space travel on mammals in preparation for the ...
Tópico(s): Glutathione Transferases and Polymorphisms
2021 - Elsevier BV | Kidney International
Sarah K. Popp, Federica Vecchio, Debra Brown, Riho Fukuda, Yuri Suzuki, Yuma Takeda, Rikako Wakamatsu, Mahalakshmi A. Sarma, Jessica Garrett, Anna Giovenzana, Emanuele Bosi, Antony Lafferty, Karen J. Brown, Elizabeth E. Gardiner, Lucy A. Coupland, Helen E. Thomas, Beng H. Chong, Christopher R. Parish, Manuela Battaglia, Alessandra Petrelli, Charmaine J. Simeonovic,
Platelet-neutrophil aggregates (PNAs) facilitate neutrophil activation and migration and could underpin the recruitment of neutrophils to the pancreas during type 1 diabetes (T1D) pathogenesis. PNAs, measured by flow cytometry, were significantly elevated in the circulation of autoantibody-positive (Aab+) children and new-onset T1D children, as well as in pre-T1D (at 4 weeks and 10-12 weeks) and T1D-onset NOD mice, compared with relevant controls, and PNAs were characterized by activated P-selectin+ ...
Tópico(s): Pancreatitis Pathology and Treatment
2022 - American Society for Clinical Investigation | JCI Insight
Masako Nishikawa, Hiroshi Kanno, Yuqi Zhou, Ting‐Hui Xiao, Takuma Suzuki, Yuma Ibayashi, Jeffrey Harmon, Shigekazu Takizawa, K. Hiramatsu, Nao Nitta, Risako Kameyama, Walker Peterson, Jun Takiguchi, Mohammad Shifat‐E‐Rabbi, Yan Zhuang, Xuwang Yin, Abu Hasnat Mohammad Rubaiyat, Yunjie Deng, Hongqian Zhang, Shigeki Miyata, Gustavo K. Rohde, Wataru Iwasaki, Yutaka Yatomi, Keisuke Goda,
A characteristic clinical feature of COVID-19 is the frequent incidence of microvascular thrombosis. In fact, COVID-19 autopsy reports have shown widespread thrombotic microangiopathy characterized by extensive diffuse microthrombi within peripheral capillaries and arterioles in lungs, hearts, and other organs, resulting in multiorgan failure. However, the underlying process of COVID-19-associated microvascular thrombosis remains elusive due to the lack of tools to statistically examine platelet ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Nature Portfolio | Nature Communications
Tomoyuki Morisawa, Yota Kunieda, Shingo Koyama, Mizue Suzuki, Yuma Takahashi, Tomokazu Takakura, Yuta Kikuchi, Tadamitsu Matsuda, Yuji Fujino, Ryuichi Sawa, Akihiro Sakuyama, Masakazu Saitoh, Tetsuya Takahashi, Toshiyuki Fujiwara,
An association between respiratory muscle weakness and sarcopenia may provide a clue to the mechanism of sarcopenia development. We aimed to clarify this relationship among community-dwelling older adults. In total, 117 community-dwelling older adults were assessed and classified into 4 groups: robust, respiratory muscle weakness, sarcopenia, and respiratory sarcopenia. The respiratory sarcopenia group (12%) had a significantly higher percentage of males and had lower BMI, skeletal muscle index, ...
Tópico(s): Cerebral Palsy and Movement Disorders
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Hiroshi Suga, Hiroya Suzuki, Yuma Shinomura, Shota Kashiwabara, Kazuhito Tsukagoshi, Tetsuo Shimizu, Yasuhisa Naitoh,
Highly stable, nonvolatile, high-temperature memory based on resistance switching was realized using a polycrystalline platinum (Pt) nanogap. The operating temperature of the memory can be drastically increased by the presence of a sharp-edged Pt crystal facet in the nanogap. A short distance between the facet edges maintains the nanogap shape at high temperature, and the sharp shape of the nanogap densifies the electric field to maintain a stable current flow due to field migration. Even at 873 ...
Tópico(s): Conducting polymers and applications
2016 - Nature Portfolio | Scientific Reports
Daichi G. Suzuki, Yuma Fukumoto, Miho Yoshimura, Yuji Yamazaki, Jun Kosaka, Shigeru Kuratani, Hiroshi Wada,
The ancestral configuration of the vertebrate head has long been an intriguing topic in comparative morphology and evolutionary biology. One peculiar component of the vertebrate head is the presence of extra-ocular muscles (EOMs), the developmental mechanism and evolution of which remain to be determined. The head mesoderm of elasmobranchs undergoes local epithelialization into three head cavities, precursors of the EOMs. In contrast, in avians, these muscles appear to develop mainly from the mesenchymal ...
Tópico(s): Congenital heart defects research
2016 - BioMed Central | Zoological Letters
Ryosuke Suzuki, Yuma Yamada, Eriko Kawamura, Hideyoshi Harashima,
Tópico(s): DNA and Nucleic Acid Chemistry
2014 - Springer Science+Business Media | Journal of Nanoparticle Research
Shuichi Suzuki, Yuma Matsumoto, Mai Tsubamoto, Ryoji Sugimura, Masatoshi Kozaki, Kenshi Kimoto, Munetaka Iwamura, Koichi Nozaki, Naoki Senju, Chiasa Uragami, Hideki Hashimoto, Yohei Muramatsu, Akinori Konno, Keiji Okada,
The recently reported efficient charge-separated system based on bipyridine-diacetylide platinum(ii) complexes was applied to photoelectric conversion systems herein, based on the design and synthesis of two triads: MTA-Pt-NDISAc (3, MTA: dimethoxytriphenylamine, Pt: platinum(ii) complex, NDISAc: thioacetate derivative linked to naphthalenediimide) and MTA-Pt-MNICOOH (4, MNICOOH: naphthaleneimide-4-carboxylic acid). The charge-separated (CS) states of triads 3 and 5 (MOM-protected 4) were effectively ...
Tópico(s): TiO2 Photocatalysis and Solar Cells
2013 - Royal Society of Chemistry | Physical Chemistry Chemical Physics
Tetsuo Kubota, Toshihiko Suzuki, Yuma Kitase, Hiroyuki Kidokoro, Yuji Miyajima, Akimasa Ogawa, Jun Natsume, Akihisa Okumura,
Rotavirus is one of the most common causes of gastroenteritis in children and is known to accompany some neurological disorders such as encephalitis/encephalopathy and seizures. Although cerebellar disorders sometime occur as a complication of rotavirus gastroenteritis in Japan, few reports have addressed these issues. Here, we report three cases of insulted cerebellums in addition to encephalitis/encephalopathy associated with rotavirus. Similar to posterior fossa syndrome after surgery, mutism ...
Tópico(s): Viral gastroenteritis research and epidemiology
2010 - Elsevier BV | Brain and Development
Takahiro Hayashi, Masayoshi Sekine, Junya Suzuki, Yuma Horio, Hirotsugu Takizawa,
P-type Bi0.4Sb1.6Te3 thermoelectric materials were prepared by an angular extrusion technique with rapidly solidified and stacked foils in a temperature range from 643 K to 838 K. Textures of the angular-extruded specimens were observed by Orientation Imaging Microscopy (OIM). The average grain size was monotonously enlarged from 4.7 to 16.1 μm while increasing the extrusion temperature. The texture of the angular-extruded specimens shows that the basal planes are preferably aligned along the extrusion ...
Tópico(s): Advanced Semiconductor Detectors and Materials
2007 - | MATERIALS TRANSACTIONS
Ryosuke Suzuki, Yuma Yamada, Hideyoshi Harashima,
The potential for protein therapy, such as the use of antibodies, and vaccines is now well accepted. However, it is difficult to enhance efficiency in protein therapy without a suitable delivery system for delivering proteins to target sites. Here we describe the development of protein delivery system, which is capable of cytoplasmic delivery as well as efficient packaging. The multifunctional envelope-type nano device (MEND), which was originally developed for the delivery of nucleic acids such ...
Tópico(s): Lipid Membrane Structure and Behavior
2007 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin
Akihiro Nakamura, Nobuyuki Honma, Yuma Tanaka, Yoshiyuki Suzuki, Yosuke Shida, Yuko Tsuda, Koushi Hidaka, Wataru Ogasawara,
Droplet-based microfluidic systems are a powerful tool for biological assays with high throughput. Water-in-oil droplets (WODLs) are typically used in droplet-based microfluidic systems to culture microorganisms and perform enzyme assays. However, because of the oil surrounding the nanoliter and picoliter volumes of WODLs, availability of suitable substrates is limited. For instance, although 7-amino-4-methylcoumarin (AMC) is commonly used as a fluorescent probe of the substrate to detect peptidase ...
Tópico(s): Biosensors and Analytical Detection
2021 - American Chemical Society | Analytical Chemistry
Tomoyuki Yano, Ryo Karakawa, Tomoyoshi Shibata, Yuma Fuse, Akiyo Suzuki, Yukiko Kuramoto, Nobuko Suesada, Hiroki Miyashita, Hidehiko Yoshimatsu,
Background A goal in ideal lower eyelid reconstruction is to achieve not only an esthetic recovery of the shape of the eyelid but also to obtain satisfactory eyelid function without damage to the corneal surface. In this report, we introduce our "Like with Like" reconstruction technique using a combined Hughes flap and swing skin flap. The Hughes flap is a tarsoconjunctival pedicled flap from the upper eyelid, and the swing skin flap is a kind of transposition flap based on the orbicularis muscle ...
Tópico(s): Facial Rejuvenation and Surgery Techniques
2021 - Elsevier BV | Journal of Plastic Reconstructive & Aesthetic Surgery
Yuma Ohari, Yuma Suzuki, Toshiyuki Shibahara, Tadashi Itagaki,
Paragonimiasis is an important food-borne zoonosis caused by Paragonimus flukes and is endemic to western Japan. However, there have been few epidemiological studies in the Tohoku district of northeastern Japan. In this study, Paragonimus metacercariae (mc) was detected in Geothelphusa dehaani (Japanese freshwater crab or Sawagani) in Iwate Prefecture. Out of the 207 Sawagani collected from 35 localities, 12 individuals from six localities were infected with Paragonimus mc. The mc were identified ...
Tópico(s): Helminth infection and control
2019 - Japanese Society of Veterinary Science | Journal of Veterinary Medical Science
Daichi Suzuki, Yuma Takida, Yukio Kawano, Hiroaki Minamide, Nao Terasaki,
Owing to their high thermal and optical performances, carbon nanotube (CNT) films are used in various photo-thermo-electric (PTE) applications, such as terahertz (THz) sensing and energy harvesting. To improve the performance of PTE devices, a device structure should be designed based on a deep understanding of the thermal and optical responses of the CNT film. However, the optical properties of CNT films in the THz frequency region remain unclear because of the difficulties associated with device ...
Tópico(s): Terahertz technology and applications
2022 - Taylor & Francis | Science and Technology of Advanced Materials
Kazuto Suzuki, Yuma Shisaka, Joshua Kyle Stanfield, Yoshihito Watanabe, Osami Shoji,
Stereoselectivity of cyclopropanation of styrene catalysed by cytochrome P450BM3 is enhanced in the presence of decoy molecules.
Tópico(s): Synthetic Organic Chemistry Methods
2020 - Royal Society of Chemistry | Chemical Communications
Takumi Watanabe, Haruka Minato, Yuma Sasaki, Seina Hiroshige, Hayato Suzuki, Nahomi Matsuki, Koki Sano, Takeshi Wakiya, Yuichiro Nishizawa, Takayuki Uchihashi, Takuma Kureha, Mitsuhiro Shibayama, Toshikazu Takata, Daisuke Suzuki,
We propose a recycling strategy for tough polymers based on microparticles. The "microparticle-based" concept allows materials recycling without loss of their properties (‘closed-loop’ recycling).
Tópico(s): Graphene and Nanomaterials Applications
2023 - Royal Society of Chemistry | Green Chemistry
Minori Goto, Yuma Yamada, Atsushi Shimura, Tsuyoshi Suzuki, Naomichi Degawa, Takekazu Yamane, Susumu Aoki, Junichiro Urabe, Shinji Hara, Hikaru Nomura, Yoshishige Suzuki,
Abstract Bolometers are rectification devices that convert electromagnetic waves into direct current voltage through a temperature change. A superconducting bolometer has a responsivity of approximately 10 6 –10 7 V/W under cryogenic temperatures at infrared wavelengths; however, no devices have realized such a high responsivity in the sub-GHz frequency region. We describe a spin bolometer with a responsivity of (4.40 ± 0.04) × 10 6 V/W in the sub-GHz region at room temperature using heat generated in ...
Tópico(s): Superconducting and THz Device Technology
2021 - Nature Portfolio | Nature Communications
Daisuke Takahashi, Naomi Hoshina, Yuma Kabumoto, Yuichi Maeda, Akari Suzuki, Hiyori Tanabe, Junya Isobe, Takahiro Yamada, Kisara Muroi, Yuto Yanagisawa, Atsuo Nakamura, Yumiko Fujimura, Aiko Saeki, Mizuki Ueda, Ryohtaroh Matsumoto, Hanako Asaoka, Julie M. Clarke, Yohsuke Harada, Eiji Umemoto, Noriko Komatsu, Takaharu Okada, Hiroshi Takayanagi, Kiyoshi Takeda, Michio Tomura, Koji Hase,
BackgroundRheumatoid arthritis (RA) is a chronic debilitating autoimmune disorder with a high prevalence, especially in industrialized countries. Dysbiosis of the intestinal microbiota has been observed in RA patients. For instance, new-onset untreated RA (NORA) is associated with the underrepresentation of the Clostridium cluster XIVa, including Lachnospiraceae, which are major butyrate producers, although the pathological relevance has remained obscure. Follicular regulatory T (TFR) cells play critical ...
Tópico(s): Pharmacological Effects of Natural Compounds
2020 - Elsevier BV | EBioMedicine
Eiko N. Minakawa, H. Akiko Popiel, Masayoshi Tada, Toshiaki Takahashi, Hiroshi Yamane, Yuji Saitoh, Yasuo Takahashi, Daisaku Ozawa, Akiko Takeda, Toshihide Takeuchi, Yuma Okamoto, Kazuhiro Yamamoto, Mari Suzuki, Hiromi Fujita, Chiyomi Ito, Hiroko Yagihara, Yuko Saito, Kei Watase, Hiroaki Adachi, Masahisa Katsuno, Hideki Mochizuki, Kentaro Shiraki, Gen Sobue, Tatsushi Toda, Keiji Wada, Osamu Onodera, Yoshitaka Nagai,
The polyglutamine (polyQ) diseases are a group of inherited neurodegenerative diseases that include Huntington's disease, various spinocerebellar ataxias, spinal and bulbar muscular atrophy, and dentatorubral pallidoluysian atrophy. They are caused by the abnormal expansion of a CAG repeat coding for the polyQ stretch in the causative gene of each disease. The expanded polyQ stretches trigger abnormal β-sheet conformational transition and oligomerization followed by aggregation of the polyQ proteins ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2020 - Oxford University Press | Brain
Yuma Takida, Kouji Nawata, Safumi Suzuki, Masahiro Asada, Hiroaki Minamide,
The sensitive detection of terahertz (THz)-wave radiation from compact sources at room temperature is crucial for real-world THz-wave applications. Here, we demonstrate the nonlinear optical detection of THz-wave radiation from continuous-wave (CW) resonant tunneling diodes (RTDs) at 0.58, 0.78, and 1.14 THz. The up-conversion process in a MgO:LiNbO3 crystal under the noncollinear phase-matching condition offers efficient wavelength conversion from a THz wave to a near-infrared (NIR) wave that is detected ...
Tópico(s): Photonic and Optical Devices
2017 - Optica Publishing Group | Optics Express
Hiroki Daijo, Yuma Hoshino, Shinichi Kai, Kengo Suzuki, Kenichiro Nishi, Yoshiyuki Matsuo, Hiroshi Harada, Kiichi Hirota,
Cigarette smoke (CS) is a major contributor to the development of a large number of fatal and debilitating disorders. However, the precise molecular mechanisms underlying the effects of CS in lung disease are largely unknown. To elucidate these pathophysiological processes, we examined the in vitro and in vivo effects of CS extract (CSE) and CS on the transcription factor, hypoxia-inducible factor 1 (HIF-1). CSE induced concentration- and time-dependent accumulation of HIF-1α protein in human lung ...
Tópico(s): Fibroblast Growth Factor Research
2016 - Nature Portfolio | Scientific Reports