Kouichi Hosoya, Motokazu Nakayama, Daisuke Tomiyama, Tetsuhiro Matsuzawa, Yumi Imanishi, Seiichi Ueda, Takashi Yaguchi,
Recently the numbers of spoilage incidents in food industry by the species of Thermoascus are increasing, but the risk of food spoilage have never been evaluated. It became obvious that their heat-resistances were higher than those of other heat-resist fungi, Byssochlamys, Hamigera and Neosartorya by our analyses. On the other hand, Thermoascus aurantiacus and Byssochlamys verrucosa had the idh gene, but they showed no patulin production in Potato dextrose broth or Czapek-glucose medium. Therefore, ...
Tópico(s): Fermentation and Sensory Analysis
2014 - Elsevier BV | Food Control
Tadashi Mikoya, Toyoko Shibukawa, Takafumi Susami, Yoshiaki Sato, Toshimoto Tengan, Hirotaka Katashima, Akihiko Oyama, Yusuke Matsuzawa, Yumi Ito, Emi Funayama,
To compare dental arch relationship outcomes following one- and two-stage palatal repair.Nonrandomized, clinical trial with concurrent control.Hokkaido University Hospital.Sixty-eight consecutively treated Japanese patients with complete unilateral cleft lip and palate.Thirty-one of the 68 patients underwent two-stage palatoplasty with delayed hard palate closure, and 37 patients underwent one-stage pushback palatoplasty.Dental casts were taken at 4.9 to 6.3 (mean: 5.2) years of age in the two-stage ...
Tópico(s): Tracheal and airway disorders
2014 - SAGE Publishing | The Cleft Palate-Craniofacial Journal
Motokazu Nakayama, Kouichi Hosoya, Daisuke Tomiyama, Takashi Tsugukuni, Tetsuhiro Matsuzawa, Yumi Imanishi, Takashi Yaguchi,
In the beverage industry, peracetic acid has been increasingly used as a disinfectant for the filling machinery and environment due to merits of leaving no residue, it is safe for humans, and its antiseptic effect against fungi and endospores of bacteria. Recently, Chaetomium globosum and Chaetomium funicola were reported resistant to peracetic acid; however, little is known concerning the detail of peracetic acid resistance. Therefore, we assessed the peracetic acid resistance of the species of ...
Tópico(s): Yeasts and Rust Fungi Studies
2013 - Elsevier BV | Journal of Food Protection
Kouichi Hosoya, Motokazu Nakayama, Tetsuhiro Matsuzawa, Yumi Imanishi, Jun Hitomi, Takashi Yaguchi,
Species of the genus Byssochlamys, heat-resistant fungi, cause the spoilage and poisoning of heat-processed acidic foods due to the formation of heat-resistant ascospores and the biosynthesis of patulin. Here we evaluated the heat resistance and patulin production of four species of Byssochlamys. Byssochlamys fulva was significantly more heat-resistant than the other species, and Byssochlamys lagunculariae and Byssochlamys nivea synthesized patulin. This is the first report of patulin production ...
Tópico(s): Mycorrhizal Fungi and Plant Interactions
2012 - Elsevier BV | Food Control
Kenji Momozawa, Atsushi Matsuzawa, Yukio Tokunaga, Shiori Abe, Yumi Koyanagi, Miho Kurita, Marina Nakano, Takao Miyake,
Currently, the cryopreservation of embryos and oocytes is essential for assisted reproductive technology (ART) laboratories worldwide. This study aimed to evaluate the efficacy of the Kitasato Vitrification System (KVS) as a vitrification device for the cryopreservation of mouse embryos to determine whether this novel device can be adapted to the field of ART. In Experiment 1, blastocysts were vitrified using the KVS. Vitrified blastocysts were warmed and subsequently cultured for 72 h. In Experiment ...
Tópico(s): Ovarian function and disorders
2017 - BioMed Central | Reproductive Biology and Endocrinology
Makoto Murakami, Ichiro Kudo, Masato Umeda, Atsushi Matsuzawa, Mayuko Takeda, Masayuki Komada, Yumi Fujimori, Katsuhiko Takahashi, Keizo Inoue,
Phospholipase A2 activity in lysates of mast cells such as rat mastocytoma RBL-2H3 cells and mouse bone marrow-derived IL-3-dependent mast cells (BMMC) was measured using phosphatidylcholine (PC), phosphatidylethanolamine (PE), or phosphatidylserine (PS) as a substrate. Both types of cells exhibited phospholipase A2 activity with a similar pH profile; the optimum pH observed with PS as a substrate was 5.5–7.4, whereas that with PE or PC was 8.0–9.0. PE and PC bearing an arachidonate at the sn-2 position ...
Tópico(s): Biomedical Research and Pathophysiology
1992 - Oxford University Press | The Journal of Biochemistry
Takashi Yaguchi, Yumi Imanishi, Tetsuhiro Matsuzawa, Kouichi Hosoya, Jun Hitomi, Motokazu Nakayama,
Species of the genus Neosartorya are heat-resistant fungi that cause the spoilage of heat-processed acidic foods due to the formation of heat-resistant ascospores, and they produce mycotoxins, such as fumitremorgins and gliotoxin. Their anamorphs are phylogenetically and morphologically very close to Aspergillus fumigatus, which has never been reported as a spoilage agent in heat-processed food products. Therefore it is important to discriminate between the species of Neosartorya and A. fumigatus ...
Tópico(s): Fungal Biology and Applications
2012 - Elsevier BV | Journal of Food Protection
Masaaki Miyata, Yumi Sakaida, Hitomi Matsuzawa, Kouichi Yoshinari, Yasushi Yamazoe,
Human fibroblast growth factor 19 (FGF19) is an enterohepatic hormone that is involved in the regulation of hepatic metabolism of bile acids, lipids, and glucose. Farnesoid X receptor (Fxr)-null mice exhibit steatosis-like symptoms, showing higher hepatic lipid levels than with the wild-type mice. We investigated the influence of FGF19 treatment on hepatic lipogenesis in Fxr-null mice. Recombinant FGF19 treatment (400 μg/kg/d) for 3 d prevented the accumulation of lipid droplets and decreased serum ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
2011 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin
Yumi Yamanashi, Tetsuro Matsuzawa,
Abstract Self-directed behaviours (SDBs) are said to be indicative of negative emotions. The present study focused on chimpanzees’ SDBs during cognitive experiments in order to investigate how each chimpanzee reacted to his or her errors and to changes in task difficulty. We recorded and analysed the behaviour of six chimpanzees during cognitive experiments at the Primate Research Institute, Kyoto University, in Japan. We compared the rate of SDBs after correct trials versus incorrect trials, and ...
Tópico(s): Animal Vocal Communication and Behavior
2010 - Cambridge University Press | Animal Welfare
Masumi Eto, Toshio Kitazawa, Fumiko Matsuzawa, Sei-ichi Aikawa, Jason A. Kirkbride, Noriyoshi Isozumi, Yumi Nishimura, David L. Brautigan, Shin‐ya Ohki,
Phosphorylation of endogenous inhibitor proteins for type-1 Ser/Thr phosphatase (PP1) provides a mechanism for reciprocal coordination of kinase and phosphatase activities. A myosin phosphatase inhibitor protein CPI-17 is phosphorylated at Thr38 through G-protein-mediated signals, resulting in a >1000-fold increase in inhibitory potency. We show here the solution NMR structure of phospho-T38-CPI-17 with rmsd of 0.36 ± 0.06 Å for the backbone secondary structure, which reveals how phosphorylation triggers ...
Tópico(s): Ion channel regulation and function
2007 - Elsevier BV | Structure
Toyoko Shibukawa, Tadashi Mikoya, Yusuke Matsuzawa, Yumi Ito, Izumi Sogabe, Kanchu Tei,
We describe our experience with a case of congenital epulis arising in both the maxillary and mandibular alveolar ridge, which showed spontaneous regression. Two distinct lesions were found in an 8-day-old newborn infant at the first medical examination: one was a sessile lesion on the maxillary alveolar ridge corresponding to the right upper deciduous canine, and the other was a pedunculated lesion on the mandibular alveolar ridge corresponding to the right lower deciduous lateral incisor. Because ...
Tópico(s): Soft tissue tumor case studies
2015 - Japanese Society of Oral and Maxillofacial Surgeons | Japanese Journal of Oral & Maxillofacial Surgery
Atsushi Tanaka, Michio Shimabukuro, Noritaka Machii, Hiroki Teragawa, Yosuke Okada, Kosuke R. Shima, Toshinari Takamura, Isao Taguchi, Itaru Hisauchi, Shigeru Toyoda, Yasushi Matsuzawa, Hirofumi Tomiyama, Minako Yamaoka‐Tojo, Hisako Yoshida, Yasunori Sato, Yumi Ikehara, Shinichiro Ueda, Yukihito Higashi, Koichi Node, Junya Ako, Hirohisa Amano, Teruo Inoue, Hideaki Jinnouchi, Atsushi Kawaguchi, Yoshiyuki Kawano, Kazuo Kimura, Akira Kurozumi, Takaaki Kusumoto, Tatsuya Maruhashi, Hirofumi Misu, Katsunori Nakamura, Manabu Narisawa, Junya Nishi, Tsuguhito Ota, Jun‐ichi Oyama, Masashi Sakuma, Kazuki Shiina, Seigo Sugiyama, Kunihiro Suzuki, Naohiko Takahashi, Yasuhiko Takemoto, Yumie Takeshita, Hiroshi Tamaki, Akira Tamura, Kenichi Tanaka, Takafumi Toita, Keiichi Torimoto, Hiroki Uehara, Fumi Uemura, Ken Yamakawa, Kunio Yufu,
Recent large trials on sodium–glucose cotransporter 2 (SGLT2) inhibitors showed that these agents improved cardiovascular outcomes in patients with type 2 diabetes (T2D) with a high risk of cardiovascular events (1). However, the underlying mechanisms of these clinical benefits and vascular effect of SGLT2 inhibitors in that patient group remain uncertain. Endothelial dysfunction is exacerbated by metabolic disorders, such as diabetes, and involved in the pathophysiology of diabetes-related cardiovascular ...
Tópico(s): Chronic Kidney Disease and Diabetes
2019 - American Diabetes Association | Diabetes Care
Kimberley J. Hockings, Nicola Bryson‐Morrison, Susana Carvalho, Michiko Fujisawa, Tatyana Humle, William C. McGrew, M. Nakamura, Gaku Ohashi, Yumi Yamanashi, Gen Yamakoshi, Tetsuro Matsuzawa,
African apes and humans share a genetic mutation that enables them to effectively metabolize ethanol. However, voluntary ethanol consumption in this evolutionary radiation is documented only in modern humans. Here, we report evidence of the long-term and recurrent ingestion of ethanol from the raffia palm (Raphia hookeri, Arecaceae) by wild chimpanzees (Pan troglodytes verus) at Bossou in Guinea, West Africa, from 1995 to 2012. Chimpanzees at Bossou ingest this alcoholic beverage, often in large quantities, ...
Tópico(s): Olfactory and Sensory Function Studies
2015 - Royal Society | Royal Society Open Science
Kazumi IKEDA, Yumi Kumagai, Yuka Nagano, Naoko MATSUZAWA, Shosuke Kojo,
Paraquat causes lung injury by oxidative stress. After 48 h of intraperitoneal administration of paraquat (50 mg/kg of body weight) to rats, the vitamin C concentration in the lungs was significantly decreased, while lung vitamin E content was increased after 12 h. These results indicate that vitamin C directly reflected the oxidative stress in the lungs.
Tópico(s): Heme Oxygenase-1 and Carbon Monoxide
2003 - Oxford University Press | Bioscience Biotechnology and Biochemistry
Kouichi Takeuchi, Kenichi Koike, Takehiko Kamijo, Shuichi Ishida, Yozo Nakazawa, Yumi Kurokawa, Kazuo Sakashita, Tatsuya Kinoshita, S. Matsuzawa, Masaaki Shiohara, Tetsuji Yamashita, Motowo Nakajima, Atsushi Komiyama,
Abstract Stem cell factor (SCF)/c-kit system is critical for human mast cell development. We thus examined the effects of STI571, an inhibitor of the c-kit tyrosine kinase receptor, on the proliferation and function of human mast cells. STI571 at concentrations of 10−6 M or higher almost completely abolished the SCF-dependent progeny generation from cord blood-derived cultured mast cells through an inhibition of the tyrosine phosphorylation of c-kit. The compound also suppressed the early phase of ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2003 - Oxford University Press | Journal of Leukocyte Biology
Kazuhiko Matsuzawa, Shoichiro Izawa, Tsuyoshi Ohkura, Hiroko Ohkura, Kiyosuke Ishiguro, Akio Yoshida, Yumi Takiyama, Masakazu Haneda, Chiaki Shigemasa, Kazuhiro Yamamoto, Shin‐ichi Taniguchi,
Promyelocytic leukaemia zinc finger (PLZF) is a transcriptional repressor that was originally isolated from a patient with promyelocytic leukaemia. PLZF also affects key elements for cell cycle progression, such as cyclin A, and can affect the tumourigenicity of various cancers. Thus far, the behaviour of PLZF in thyroid carcinoma remains unclear. We analysed the expression profile of PLZF in different types of benign and malignant thyroid lesions as well as in normal thyroid tissue. Specifically, ...
Tópico(s): Thyroid Cancer Diagnosis and Treatment
2014 - BioMed Central | BMC Endocrine Disorders
S Matsuzawa, Hiroko Kimura, Ryo Kobayashi, Yukio Itoh, Yumi Bannai,
Volumes of agglutinates produced by the microtiter latex antiglobulin test (LAGT) were measured by an electronic data processing (EDP) method using a particle volume distribution analyzer. This method proved highly sensitive for quantitating weak antibodies, such as anti-digoxin and anti-DNP. EDP measurement of the microtiter latex antiglobulin-inhibition test (LAGIT) is also a suitable method for quantitating HCG, digoxin and DNP.
Tópico(s): Biosimilars and Bioanalytical Methods
1983 - Elsevier BV | Journal of Immunological Methods
Hiroyuki Takamiya, Yumi Tanahashi, Tosiki Matsuyama, Tetsuya Tanigami, Kazuo Yamaura, Shuji Matsuzawa,
Abstract The color development due to the complex formation of poly(vinyl alcohol) (PVA) with iodine increased with increasing syndiotacticity of PVA. Isotactic PVA showed no color development. The color development of syndiotacticity‐rich PVA film decreased with increasing annealing temperature for films before complexization, whereas that of atactic (commercial) PVA increased with it. Lower temperatures, the elongation of complex film, and the presence of boric acid enhanced the absorbance at 600 ...
Tópico(s): Polymer Nanocomposite Synthesis and Irradiation
1993 - Wiley | Journal of Applied Polymer Science
Susana Carvalho, Yumi Yamanashi, Gen Yamakoshi, Tetsuro Matsuzawa,
Tópico(s): Animal Behavior and Reproduction
2010 - Kyoto University | Pan Africa News
Atsushi Suzuki, Yumi Tsutomi, Motomu Shimizu, Akio Matsuzawa,
The death receptor Fas transduces apoptotic death signaling upon stimulation with the Fas ligand. We previously reported that Fas contributes to vaginal cell death observed during the estrus cycle and after estrogen deprivation, using the functional Fas-lacking lpr and lprcg mutant mouse. In the present study, we investigated whether the Fas ligand also plays a dominant role in vaginal cell death using the functional Fas ligand-lacking gld mutant mouse. Our results demonstrated that vaginal cells ...
Tópico(s): Immune Response and Inflammation
1999 - Springer Nature | Cell Death and Differentiation
S Matsuzawa, Yukio Itoh, Hiroko Kimura, Yumi Bannai,
Particle volume distribution analysis method was applied to the immunologic agglutination of latex particles. By using monodisperse and stable latex particles, coated with antigen, agglutination caused by corresponding antibody was quantitatively proved. This method determined the presence of allospecific natural anti-IgG factor in a serum of non-immunized rabbit and anti-human IgG factor in healthy persons' sera.
Tópico(s): Protein purification and stability
1980 - Japan Academy | Proceedings of the Japan Academy Series B
Atsushi Tanaka, Michio Shimabukuro, Yosuke Okada, Isao Taguchi, Minako Yamaoka‐Tojo, Hirofumi Tomiyama, Hiroki Teragawa, Seigo Sugiyama, Hisako Yoshida, Yasunori Sato, Atsushi Kawaguchi, Yumi Ikehara, Noritaka Machii, Tatsuya Maruhashi, Kosuke R. Shima, Toshinari Takamura, Yasushi Matsuzawa, Kazuo Kimura, Masashi Sakuma, Jun‐ichi Oyama, Teruo Inoue, Yukihito Higashi, Shinichiro Ueda, Koichi Node,
Abstract Background Type 2 diabetes mellitus (T2DM) is characterized by systemic metabolic abnormalities and the development of micro- and macrovascular complications, resulting in a shortened life expectancy. A recent cardiovascular (CV) safety trial, the EMPA-REG OUTCOME trial, showed that empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, markedly reduced CV death and all-cause mortality and hospitalization for heart failure in patients with T2DM and established CV disease (CVD). ...
Tópico(s): Chronic Kidney Disease and Diabetes
2017 - BioMed Central | Cardiovascular Diabetology
Michiko Konno, Yumi Sano, K. Okudaira, Y. Kawaguchi, Y. Yamagishi-Ohmori, Shinya Fushinobu, Hiroshi Matsuzawa,
Cyclophilins facilitate the peptidyl‐prolyl isomerization of a trans ‐isomer to a cis ‐isomer in the refolding process of unfolded proteins to recover the natural folding state with cis ‐proline conformation. To date, only short peptides with a cis ‐form proline have been observed in complexes of human and Escherichia coli proteins of cyclophilin A, which is present in cytoplasm. The crystal structures analyzed in this study show two complexes in which peptides having a trans ‐form proline, i.e. succinyl‐ ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2004 - Wiley | European Journal of Biochemistry
Yasumitsu Fujie, Noemi Fusaki, Tomohiko Katayama, Makoto Hamasaki, Yumi Soejima, Minami Soga, Hiroshi Ban, Mamoru Hasegawa, Satoshi Yamashita, Shigemi Kimura, Saori Suzuki, Tetsuro Matsuzawa, Hirofumi Akari, Takumi Era,
Induced pluripotent stem cells (iPSCs) are potentially valuable cell sources for disease models and future therapeutic applications; however, inefficient generation and the presence of integrated transgenes remain as problems limiting their current use. Here, we developed a new Sendai virus vector, TS12KOS, which has improved efficiency, does not integrate into the cellular DNA, and can be easily eliminated. TS12KOS carries KLF4, OCT3/4, and SOX2 in a single vector and can easily generate iPSCs from ...
Tópico(s): Virus-based gene therapy research
2014 - Public Library of Science | PLoS ONE
Kimihito Nakamura, Haruhiko Horino, T. Matsuzawa, Yumi Yoshioka, Takehide Hama,
複数水源を有する水田灌漑地域における地下水取水の実態を,愛知川扇状地を例に整理し,地下水取水量の規定要因と地下水取水のあり方を考察した。地下水は受益地の送配水管理を行う土地改良区と末端分水工掛内の水管理を行う農家や水利組合による二つの管理主体により取水されている。受益地全体における地下水利用は地表水取水量自体の不足を補うとともに,気象条件による地表水取水量の変動を補完していること,特に分水工取水強度が十分でない末端分水工掛では,降水量や栽培管理状況に応じた揚水機管理によって便利な水として地下水を利用していることを示した。適切な地下水取水のためには土地改良区と水利組合の分担・連携が重要である。
Tópico(s): Coal Combustion and Slurry Processing
2021 - | Journal of Groundwater Hydrology
Hideki Azuma, Akiko Fujita, Kazuyuki Otsuki, Yumi Nakano, Takahiro Kamao, Chié Nakamura, Junko Fujioi, Hirohumi Otake, Makoto Nishigaki, Masako Suzuki, Miyako Kataoka, Takahiro Matsuzawa, Manabu Sonoda, Shutaro Nakaaki, Yoshie Murata, Tatsuo Akechi, Toshi A. Furukawa,
Objectives: Electroconvulsive therapy (ECT) has been associated with memory and neuropsychological changes, but which features of ECT are associated with those changes have not been well investigated. The aim of this hypothesis-generation study was to examine correlations between ictal electroencephalographic (EEG) characteristics and cognitive side effects after ECT. Methods: Eight patients with major depressive disorder were examined with the Wechsler Memory Scale-Revised (WMS-R), the Stroop test, ...
Tópico(s): Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
2007 - Lippincott Williams & Wilkins | Journal of Ect
Atsushi Tanaka, Michio Shimabukuro, Hiroki Teragawa, Hisako Yoshida, Yosuke Okada, Toshinari Takamura, Isao Taguchi, Shigeru Toyoda, Hirofumi Tomiyama, Shinichiro Ueda, Yukihito Higashi, Koichi Node, Junya Ako, Hirohisa Amano, Itaru Hisauchi, Yumi Ikehara, Hideaki Jinnouchi, Yoshiyuki Kawano, Kazuo Kimura, Akira Kurozumi, Takaaki Kusumoto, Noritaka Machii, Tatsuya Maruhashi, Yasushi Matsuzawa, Hirofumi Misu, Manabu Narisawa, Tsuguhito Ota, Jun‐ichi Oyama, Masashi Sakuma, Kazuki Shiina, Kosuke R. Shima, Seigo Sugiyama, Kunihiro Suzuki, Naohiko Takahashi, Yasuhiko Takemoto, Yumie Takeshita, Hiroshi Tamaki, Kenichi Tanaka, Akira Tamura, Keiichi Torimoto, Minako Yamaoka‐Tojo, Hiroki Uehara, Fumi Uemura, Ken Yamakawa, Kunio Yufu,
Tópico(s): Diabetes Management and Research
2024 - Springer Nature | Hypertension Research
Yumi Kinugasa, Miki Hieda, Masatsugu Hori, Shigeki Higashiyama,
... Hanakawa Y. Ohmoto H. Yoshino K. Shirakata Y. Matsuzawa Y. Hashimoto K. Taniguchi N. J. Cell Biol. ... Hanakawa Y. Ohmoto H. Yoshino K. Shirakata Y. Matsuzawa Y. Hashimoto K. Taniguchi N. J. Cell Biol. ... Yamamoto K. Nishida M. Nakamura T. Yamashita S. Matsuzawa Y. Taniguchi N. J. Clin. Invest. 1995; 95: ... Hanakawa Y. Ohmoto H. Yoshino K. Shirakata Y. Matsuzawa Y. Hashimoto K. Taniguchi N. J. Cell Biol. ... Hanakawa Y. Ohmoto H. Yoshino K. Shirakata Y. Matsuzawa Y. Hashimoto K. Taniguchi N. J. Cell Biol. ...
Tópico(s): Virus-based gene therapy research
2007 - Elsevier BV | Journal of Biological Chemistry
Nobuaki Hamazaki, Takashi Masuda, Kentaro Kamiya, Ryota Matsuzawa, Kohei Nozaki, Shinya Tanaka, Yumi Kamada, Kanae Yabu, Takeshi Nakamura, Minoru Tabata, Emi Maekawa, Chiharu Noda, Minako Yamaoka‐Tojo, Junya Ako,
Background: Decreased parasympathetic activity and respiratory muscle weakness are known as indicators for poor outcome in patients with chronic heart failure (CHF). Although the effect of respiratory modulation on autonomic system has been documented, the relationship between respiratory muscle strength and parasympathetic activity is still unknown. The present study aimed to investigate the influence of respiratory muscle weakness on parasympathetic activity in CHF patients. Methods: We studied ...
Tópico(s): Heart Rate Variability and Autonomic Control
2016 - Lippincott Williams & Wilkins | Circulation
Shinya Tanaka, Takashi Masuda, Kentaro Kamiya, Nobuaki Hamazaki, Ryota Matsuzawa, Kohei Nozaki, Ryosuke Shimizu, Yumi Kamada, Akihiro Aoyama, Chiharu Noda, Emi Maekawa, Minako Yamaoka‐Tojo, Junya Ako,
Background:Reduced exercise capacity is well known to increase mortality in patients with chronic heart failure (CHF). Although a symptomatic peripheral arterial disease (PAD) decreases exercise capacity in CHF patients, the relation of an asymptomatic PAD to its reduction is still unknown. The purpose of this study was to investigate whether an asymptomatic PAD contributed to a delay in recovery from reduced exercise capacity after hospital discharge in CHF patients. Methods: We studied 231 CHF patients ( ...
Tópico(s): Peripheral Artery Disease Management
2014 - Lippincott Williams & Wilkins | Circulation