Produção Nacional
Revisado por pares
Juliano Perottoni, Oscar E. D. Rodrigues, Márcio W. Paixão, Gilson Zeni, Luciana Pereira Lobato, Antônio L. Braga, João Batista Teixeira da Rocha, Tatiana Emanuelli,
This paper evaluates the ability of organoselenium compounds [ebselen, selenocystine N-ethyl-carbamate (SeCis), bis-4-isopropyl-2-oxazolinyl phenyl diselenide (AASe)] to prevent HgCl(2) toxicity. Rats were injected with HgCl(2) (0 or 17 micromol/kg, sc) 6 h after organoselenium compounds had been injected (0 or 50 micromol/kg, sc). In vivo, HgCl(2) inhibited renal ALA-D activity ( approximately 48%), increased TBARS level in kidney ( approximately 52%) and reduced the hepatic content of non-protein thiol ...
Tópico(s): Organoselenium and organotellurium chemistry
2003 - Elsevier BV | Food and Chemical Toxicology
Produção Nacional
Revisado por pares
Zeni Terezinha Gonçalves Pereira, Denise Quaresma da Silva,
This study proposes an investigation about the active methodology called "inverted classroom" and its practices in basic education, problematizing how they occur. In the introduction, we justify the importance of the topic as an investigative focus. Methodologically, it is a qualitative study, it was used a bibliographical review in dissertations produced in a national scope that included the active methodology methodology, inverted classroom, and the search of the data was carried out in the period ...
Tópico(s): Education and Digital Technologies
2018 - Red Iberoamericana de Investigación sobre Cambio y Eficacia Escolar (RINACE) | REICE Revista Iberoamericana sobre Calidad Eficacia y Cambio en Educación
Produção Nacional
Revisado por pares
Tiago da Luz Fiuza, Cláudia S. Oliveira, Michael D. Costa, Cláudia S. Oliveira, Gilson Zeni, Maria Estér Pereira,
This work investigated the preventive effect of diphenyl diselenide [(PhSe)2] on renal and hepatic toxicity biomarkers and oxidative parameters in adult mice exposed to mercury chloride (HgCl2). Selenium (Se) and mercury (Hg) determination was also carried out. Mice received a daily oral dose of (PhSe)2 (5.0 mg/kg/day) or canola oil for five consecutive days. During the following five days, the animals were treated with a daily subcutaneous dose of HgCl2 (5.0 mg/kg/day) or saline (0.9%). Twenty-four hours ...
Tópico(s): Mercury impact and mitigation studies
2014 - Elsevier BV | Journal of Trace Elements in Medicine and Biology
Produção Nacional
Revisado por pares
Marina Uchoa Lopes Pereira, Laura Lamas Martins Gonçalves, Cristina Maria Douat Loyola, Patrícia Sampaio da Anunciação, Rosane da Silva Días, Irla Nunes Reis, Lays Amorim Silva Pereira, Zeni Carvalho Lamy,
RESUMO Objetivo: Analisar a comunicação da morte do filho e o apoio ao luto de mulheres no período puerperal. Métodos: Trata-se de uma pesquisa com abordagem qualitativa realizada em uma capital do Nordeste. Foram aplicadas entrevistas semiestruturadas com 15 mulheres cujos recém-nascidos faleceram entre julho de 2012 e julho de 2014. As entrevistas abordaram questões acerca da morte do filho e do processo de luto. Foi realizada Análise de Conteúdo na modalidade temática. Resultados: As mulheres ...
Tópico(s): Patient Dignity and Privacy
2018 - Elsevier BV | Revista Paulista de Pediatria
Produção Nacional
Revisado por pares
María do Carmo Leal, Sônia Duarte de Azevedo Bittencourt, Ana Paula Esteves Pereira, Bárbara Vasques da Silva Ayres, Luiza Beatriz Ribeiro Acioli de Araújo Silva, Érika Bárbara Abreu Fonseca Thomaz, Zeni Carvalho Lamy, Marcos Nakamura‐Pereira, Jacqueline Alves Torres, Silvana Granado Nogueira da Gama, Rosa Maria Soares Madeira Domingues, Maria Esther de Albuquerque Vilela,
Resumo: Este artigo tem como objetivo descrever os primeiros resultados de dois estudos avaliativos, um sobre a Rede Cegonha e outro sobre o projeto Parto Adequado, denominados, respectivamente, de avaliação da Rede Cegonha e Nascer Saudável, e identificar possíveis melhorias em comparação ao estudo Nascer no Brasil. Ambos os estudos têm desenho seccional, realizados em 2017. O estudo avaliação da Rede Cegonha incluiu todas as 606 maternidades públicas e mistas envolvidas na Rede Cegonha e um total ...
Tópico(s): Maternal and Neonatal Healthcare
2019 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Produção Nacional
Revisado por pares
Jonatas Zeni Klafke, Roberta Lelis Dias Pereira, Gabriela Elisa Hirsch, Mariana Migliorini Parisi, Fernando Garcez Porto, Amanda Spring de Almeida, Fabiane Horbach Rubin, Aline Schmidt, H. Beutler, Sabrina Nascimento, Gabriela Trevisan, Indiara Brusco, Sara Marchesan Oliveira, Marta Maria Medeiros Frescura Duarte, Thiago Duarte, Paulo Ricardo Nazário Viecili,
Atherosclerosis is an inflammatory disease that affects the arterial wall leading to myocardial, cerebral, and peripheral ischemic syndromes. The use of low doses of aspirin inhibits platelet aggregation and inflammation and prevents cardiovascular mortality. However, ASA may produce hemorrhagic events. Thus, several studies have sought new natural compounds to suppress platelet aggregation without causing serious adverse effects.In this sense, this study aims to compare the effects of Campomanesia ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2015 - Elsevier BV | Phytomedicine
Produção Nacional
Revisado por pares
Hélio A. Stefani, Rodrigo Cella, Felipe Augusto Dörr, Cláudio M. P. Pereira, Gilson Zeni, M. Teixeira Gomes,
The palladium-catalyzed cross-coupling reaction between potassium alkynyltrifluoroborate salts and vinylic tellurides proceeds readily to afford 1,3-enynes with moderate to good yields.
Tópico(s): Catalytic Cross-Coupling Reactions
2004 - Elsevier BV | Tetrahedron Letters
Produção Nacional
Revisado por pares
Marilise Escobar Bürger, Roselei Fachinetto, Caroline Wagner, Juliano Perottoni, Romaiana Picada Pereira, Gilson Zeni, João Batista Teixeira da Rocha,
Recently, we have described the beneficial effects of Diphenyl diselenide, an organochalcogen with glutathione peroxidase-like activity, on reserpine-induced orofacial dyskinesia in old rats. In this study, our aim was to examine the effects of diselenide on haloperidol-induced orofacial dyskinesia in rats. Male wistar rats received one single dose of Haloperidol decanoate (57 mg/kg/im) or control. After this dose, the animals received daily administration of diphenyl diselenide (1, 5 or 10 mg/kg/ ...
Tópico(s): Medicinal Plant Extracts Effects
2006 - Elsevier BV | Brain Research Bulletin
Produção Nacional
Revisado por pares
Hélio A. Stefani, Rodrigo Cella, Felipe Augusto Dörr, Cláudio M. P. Pereira, Fábio Pereira Gomes, Gilson Zeni,
A convenient and inexpensive ultrasound-assisted preparation of functionalized arylacetylenes using metallic lithium is reported.
Tópico(s): Coordination Chemistry and Organometallics
2005 - Elsevier BV | Tetrahedron Letters
... Robson Tetsuo Sasaki, Natália Garrido Grossi, Rafael Tardeli Zeni, Daniel Martinez Saez, Ivair Donizeti Gonçalves, and Marcelo Cavenaghi Pereira da Silva1 August 2017 | Photomedicine and Laser Surgery, ...
Tópico(s): Dermatologic Treatments and Research
2012 - Mary Ann Liebert, Inc. | Photomedicine and Laser Surgery
Produção Nacional
Revisado por pares
Daniel Batista da Cunha, Ana Vitória Pupo Silvestrini, Ana Carolina Gomes da Silva, Deborah Maria de Paula Estevam, Flávia Lino Pollettini, Juliana de Oliveira Navarro, Armindo Antônio Alves, Ana Laura Remédio Zeni Beretta, Joyce Maria Annichino Bizzacchi, Lílian Cristina Pereira, Maurício V. Mazzi,
The chemical composition of snake venoms is a complex mixture of proteins and peptides that can be pharmacologically active. Crotamine, a cell-penetrating peptide, has been described to have antimicrobial properties and it exerts its effects by interacting selectively with different structures, inducing changes in the ion flow pattern and cellular responses. However, its real therapeutic potential is not yet fully known. Bearing in mind that crotamine is a promising molecule in therapeutics, this ...
Tópico(s): Lipid Membrane Structure and Behavior
2018 - Elsevier BV | Toxicon
Produção Nacional
Revisado por pares
Amanda Keller Siqueira, Tatiana Salerno, Gustavo Henrique Batista Lara, Larissa Anuska Zeni Condas, Valéria Cataneli Pereira, Danilo Flávio Moraes Riboli, Fernando José Paganini Listoni, Aristeu Vieira da Silva, Domingos da Silva Leite, Maria de Lourdes Ribeiro de Souza da Cunha, Márcio Garcia Ribeiro,
A emergência de estafilococos multirresistentes e resistentes à meticilina, isolados de animais, alimentos e humanos é uma preocupação em saúde pública. Esses micro-organismos produzem diferentes toxinas relacionadas à intoxicação alimentar em humanos. Este estudo caracterizou Staphylococcus spp. isolados em duas fazendas orgânicas no Brasil. Foram coletadas 259 amostras de leite em duas propriedades leiteiras orgânicas, nas quais 58 (22,4%) estirpes de Staphylococcus spp. foram isoladas. A maior ...
Tópico(s): Probiotics and Fermented Foods
2017 - UNIVERSIDADE DE SÃO PAULO | Brazilian Journal of Veterinary Research and Animal Science
Produção Nacional
Revisado por pares
Patrícia Sampaio da Anunciação, Zeni Carvalho Lamy, Marina Uchoa Lopes Pereira, Hellyne Giselle Reis Madeira, Cristina Douat Loyola, Laura Lamas Martins Gonçalves, Fernando Lamy Filho,
Resumo: O objetivo deste estudo foi compreender como as mães interpretam e explicam a morte de seus filhos no período neonatal. Trata-se de uma pesquisa de abordagem qualitativa. Foram utilizadas entrevistas semiestruturadas com 15 mulheres residentes no Município de São Luís, Maranhão, Brasil, cujos recém-nascidos morreram no período de julho de 2012 a julho de 2014. A coleta de dados foi realizada entre 1º de abril e 29 de agosto de 2014. As entrevistas incluíram perguntas acerca do trabalho de ...
Tópico(s): Maternal and Perinatal Health Interventions
2018 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Produção Nacional
Revisado por pares
Francielle Zeni, Michele Pereira De Liz, Dorivaldo Duarte, Ana Lúcia Bertarello Zeni,
O transtorno de ansiedade generalizado (TAG) é uma doença de alta prevalência devido ao estresse e à exigência contemporânea. Com isso, há grande uso de ansiolíticos com efeitos adversos. O objetivo do estudo foi analisar as plantas medicinais e fitoterápicos que constam nos documentos do Ministério da Saúde e podem ser indicadas por profissionais no Sistema Único de Saúde (SUS) para o tratamento complementar do TAG. Esta revisão bibliográfica foi elaborada principalmente pelos documentos do Ministério ...
Tópico(s): Olfactory and Sensory Function Studies
2021 - Federal Council of Pharmacy | Infarma - Ciências Farmacêuticas
Maria Emília Miranda Álvares, Érika Bárbara Abreu Fonseca Thomaz, Zeni Carvalho Lamy, Rachel Vilela de Abreu Haickel Nina, Marina Uchoa Lopes Pereira, João Batista Santos Garcia,
Síndrome de burnout entre profissionais de saúde nas unidades de terapia
Tópico(s): Stress and Burnout Research
2020 - Associação de Medicina Intensiva Brasileira | Revista Brasileira de Terapia Intensiva
Produção Nacional
Revisado por pares
Rafael Porto Ineu, Matheus Mülling dos Santos, Olga Soares do Rêgo Barros, Cristina W. Nogueira, João Batista Teixeira da Rocha, Gilson Zeni, Maria Estér Pereira,
Tópico(s): Vanadium and Halogenation Chemistry
2012 - Springer Science+Business Media | Cell Biology and Toxicology
Guilherme Lopes, Nunzio Cennamo, Luigi Zeni, Ragini Singh, Santosh Kumar, A.J.S. Fernandes, F.M. Costa, Sónia O. Pereira, Carlos Marques,
Optical fiber sensors show potential for monitoring multiple parameters essential to the growth and health of fish, particularly the pH value of the aquaculture medium. Two types of optical fiber sensors, using tapered silica single mode fibers with a Bragg grating inscribed and D-shaped plastic optical fibers (home-made and reused) were produced. A pH-sensitive layer made of polyaniline (PANI) was deposited on the optical fibers' surface. The sensors demonstrated reproducibility and repeatability ...
Tópico(s): Conducting polymers and applications
2023 - Elsevier BV | Optics & Laser Technology
Cátia Leitão, Sónia O. Pereira, Carlos Marques, Nunzio Cennamo, Luigi Zeni, Madina Shaimerdenova, Takhmina Ayupova, Daniele Tosi,
In the last years, optical fiber sensors have proven to be a reliable and versatile biosensing tool. Optical fiber biosensors (OFBs) are analytical devices that use optical fibers as transducers, with the advantages of being easily coated and biofunctionalized, allowing the monitorization of all functionalization and detection in real-time, as well as being small in size and geometrically flexible, thus allowing device miniaturization and portability for point-of-care (POC) testing. Knowing the potential ...
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2022 - Multidisciplinary Digital Publishing Institute | Biosensors
Paula Zeni Miessa Lawall, Adelyne Maria Mendes Pereira, Josué Miguel de Oliveira, Kellen Cristina da Silva Gasque,
Resumo: Introdução: O Brasil está em um amplo processo de fortalecimento das residências médicas nas áreas básicas, porém existe a necessidade de um currículo estruturado para qualificar a formação do preceptor. Objetivo: Este estudo teve como objetivo construir uma matriz dialógica para orientar a formação educacional da preceptoria em medicina de família e comunidade (MFC). Método: Por meio de um estudo qualitativo-analítico, analisaram-se três programas de preceptoria médica no Brasil: Associação ...
Tópico(s): Innovations in Medical Education
2023 - Associção Brasileira de Educação Médica | Revista Brasileira de Educação Médica
Francesco Arcadio, Simone Soares, Jan Nedoma, Dayana Aguiar, Ana C. Pereira, Luigi Zeni, Nunzio Cennamo, Carlos Marques,
Abstract A surface plasmon resonance (SPR) phenomenon implemented via D-shaped polymer optical fiber (POF) is exploited to realize cortisol biosensors. In this work, two immonosensors are designed and developed for the qualitative as well as quantitative measurement of cortisol in artificial and real samples. The performances of the POF-based biosensors in cortisol recognition are achieved using different functionalization protocols to make the same antibody receptor layer over the SPR surface via ...
Tópico(s): Aquaculture disease management and microbiota
2024 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Rafael Porto Ineu, Maria Estér Pereira, Michael Aschner, Cristina W. Nogueira, Gilson Zeni, João Batista Teixeira da Rocha,
The aim of the present study was to evaluate if diphenyl diselenide administered by oral route was effective in restoring gastric lesions induced by ethanol. The possible involvement of oxidative stress in diphenyl diselenide antiulcer effect was also evaluated. Different doses of diphenyl diselenide (dissolved in soya bean oil, 1 mL/kg) were administered orally 1 h before (pre-treatment study) or 1 h after ethanol (70%, v/v, 2 mL/kg, post-treatment study). Ulcer lesions were quantified 1 h after ethanol ...
Tópico(s): Antioxidant Activity and Oxidative Stress
2008 - Elsevier BV | Food and Chemical Toxicology
Daniel Zeni Rispoli, Paulo M. Camargo, José L. Pires, Vinícius Ribas Fonseca, Karina K. Mandelli, Marcela A.C. Pereira,
Idiopathic hypertrophy of the masseter muscle is a rare disorder of unknown cause. Some authors associate it with the habit of chewing gum, temporo-mandibular joint disorder, congenital and functional hypertrophies, and emotional disorders (stress and nervousness). Most patients complain of the cosmetic change caused by facial asymmetry, also called square face, however, symptoms such as trismus, protrusion and bruxism may also occur. The goals of the present investigation were: to report a case ...
Tópico(s): Oropharyngeal Anatomy and Pathologies
2008 - Elsevier BV | Brazilian Journal of Otorhinolaryngology
Daniel Zeni Rispoli, Paulo M. Camargo, José L. Pires, Vinícius Ribas Fonseca, Karina K. Mandelli, Marcela A.C. Pereira,
A hipertrofia idiopática do músculo masseter (HIM) é uma patologia pouco freqüente e de causa desconhecida. Alguns autores correlacionam tal condição com hábitos de mascar gomas, disfunção da articulação temporomandibular (ATM), hipertrofias congênitas e funcionais, e distúrbios emocionais (nervosismo e ansiedade). A maioria dos pacientes queixa-se da alteração estética decorrente da assimetria facial, também chamada "face quadrada", no entanto, sintomas como trismo, protrusão e bruxismo também podem ...
Tópico(s): Facial Nerve Paralysis Treatment and Research
2008 - Sociedade Brasileira de Otorrinolaringologia | Revista Brasileira de Otorrinolaringologia
Produção Nacional
Revisado por pares
Seigo Nagashima, Anderson Azevedo Dutra, Mayara Pezzini Arantes, Rafaela Chiuco Zeni, Carolline Konzen Klein, Flávia Centenaro de Oliveira, Giulia Werner Piper, Isadora Drews Brenny, Marcos Roberto Curcio Pereira, Rebecca Benício Stocco, Ana Paula Camargo Martins, Eduardo Morais de Castro, Caroline Busatta Vaz de Paula, Andréa Novais Moreno-Amaral, Cleber Machado‐Souza, Cristina Pellegrino Baena, Lúcia de Noronha,
Mast cells (MCs) have relevant participation in inflammatory and vascular hyperpermeability events, responsible for the action of the kallikrein-kinin system (KKS), that affect patients inflicted by the severe form of COVID-19. Given a higher number of activated MCs present in COVID-19 patients and their association with vascular hyperpermeability events, we investigated the factors that lead to the activation and degranulation of these cells and their harmful effects on the alveolar septum environment ...
Tópico(s): Adenosine and Purinergic Signaling
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Produção Nacional
Revisado por pares
T. Trovão, Milady Cutrim Vieira Cavalcante, M.C. Rodrigues, Alexandre Archanjo Ferraro, Heloísa Bettiol, Maria da Conceição Pereira Saraiva, Zeni Carvalho Lamy, Fernando Lamy Filho,
The introduction of early complementary feeding (ECF) is determined by different factors depending on when it occurs. The objective of this study was to analyze factors associated with the introduction of ECF in two different moments of the infant's life: from zero to three and from four to five months of age. A cohort with 3,306 dyads studied in the BRISA survey in São Luis/MA in 2010 was used. Questionnaires were applied at birth and at follow-up when the infants were 15 to 36 months of age of ...
Tópico(s): Child Nutrition and Water Access
2020 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Juliana Soares Otero, Gabriela Elisa Hirsch, Jonatas Zeni Klafke, Fernando Garcez Porto, Amanda Spring de Almeida, Sabrina Nascimento, Aline Schmidt, Brenda da Silva, Roberta Lelis Dias Pereira, Mônica Jaskulski, Mariana Migliorini Parisi, Naiara dos Santos Guarda, Rafael Noal Moresco, Carlos Alberto Mayora Aita, Paulo Ricardo Nazário Viecili,
Cardiovascular diseases of thrombotic origin are related to high mortality and standard therapeutic agent used in this case is acetylsalicylic acid (ASA), but serious adverse events may occur. However, recent data has suggested the plant Campomanesia xanthocarpa has antiplatelet activity and could be a viable alternative. In this study we investigated the effects of the encapsulated powder of this plant in human platelet aggregation.23 healthy subjects were randomly divided into three groups: (1) ...
Tópico(s): Phytochemistry Medicinal Plant Applications
2017 - Elsevier BV | Thrombosis Research
Produção Nacional
Revisado por pares
Débora Delwing Dal Magro, Roberto Roecker, Gustavo M. Junges, André Felipe Rodrigues, Daniela Delwing de Lima, José Geraldo Pereira da Cruz, Ângela Terezinha de Souza Wyse, Heloisa S. Pitz, Ana Lúcia Bertarello Zeni,
We investigated, in vivo (acute and chronic), the effects of proline on thiobarbituric acid-reactive substances (TBA-RS) and on the activities of antioxidant enzymes such as catalase (CAT), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) in renal tissues (cortex and medulla) of rats. For acute administration, 29-day-old rats received a single subcutaneous injection of proline (18.2μmol/g body weight) or an equivalent volume of 0.9% saline solution and were sacrificed 1h later. For chronic ...
Tópico(s): Heavy Metals in Plants
2016 - Elsevier BV | Biomedicine & Pharmacotherapy
Produção Nacional
Graziela Rissetti, Débora Zeni, Bárbara Roberta Ongaratti, Júlia Fernanda Semmelmann Pereira‐Lima, Carolina Garcia Soares Leães, Miriam da Costa Oliveira,
Dyslipidemia is prevalent among patients with hypopituitarism, especially in those with growth hormone (GH) deficiency. This study aimed to evaluate the response to statin therapy among adult patients with dyslipidemia and hypopituitarism.A total of 113 patients with hypopituitarism following up at a neuroendocrinology unit were evaluated for serum lipid levels. Dyslipidemia was diagnosed in 72 (63.7%) of these patients. A control group included 57 patients with dyslipidemia and normal pituitary function. ...
Tópico(s): Lipid metabolism and disorders
2020 - Brazilian Society of Endocrinology and Metabolism | Archives of Endocrinology and Metabolism
Produção Nacional
Raquel Piletti, Alexandra Monego Bugiereck, Abrão Pereira, E. Gussati, Jacir Dal Magro, Josiane Maria Muneron de Mello, Francieli Dalcanton, Raquel Zeni Ternus, Cíntia Soares, Humberto Gracher Riella, Márcio Antônio Fiori,
Eugenol is natural oil that has excellent antibacterial properties but cannot be used to fabricate many products that require thermal processing. One possible alternative to the use of the eugenol molecules in high-temperature processes is the encapsulation of these molecules in a structure that is not toxic and is resistant to thermal treatment. This work investigated the encapsulation process of eugenol molecules in β-cyclodextrine and the antibacterial properties of eugenol-β-cyclodextrine (the ...
Tópico(s): Ionic liquids properties and applications
2017 - Elsevier BV | Materials Science and Engineering C
Produção Nacional
Revisado por pares
Tatiana Salerno, Amanda Keller Siqueira, José Paes de Almeida Nogueira Pinto, Maria de Lourdes Ribeiro de Souza da Cunha, Patrícia Kelly Silvestre, Larissa Anuska Zeni Condas, Gustavo Henrique Batista Lara, Juliano Gonçalves Pereira, Aristeu Vieira da Silva, Fernando José Paganini Listoni, Lorrayne de Souza Araújo Martins, Rodrigo Garcia Motta, Márcio Garcia Ribeiro,
Many infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (< 8.0 oD). Caloric intake showed a wide variation in cream content (4%), ...
Tópico(s): Probiotics and Fermented Foods
2021 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo