Andrew Robson, Marc Roche, Carl Mortished International Business Editor and James Doran, Jon Ashworth, Raymond Snoddy Media Editor, Robert Cole, Rupert Mellor, Andrew Pierce, DJM, Alexandra Frean, Greg Hurst Political Correspondent, Roger Maynard and Laura Peek, Gary Duncan, John Bryce, Adam LeBor Central Europe Correspondent, Adrian Cosker, Bernard Norris, Peter Lansley, Robert Thicknesse, Paul Hoggart, Mark Souster, Stephen Smith, Laura Peek, Daniel McGrory and Richard Ford, Philip Howard, Richard Coleman, Christine Seib, David Chater, Michael Binyon, James Bone, Nic Hopkins, Alexandra Frean Social Affairs Correspondent, Peter Lansley and Ian Winrow, Elizabeth Judge, Patrick Barkham and Marie Tourres, Gabrielle Starkey, Patrick Kidd, Bob Stanley, E. F. D. C, Sam Marlowe, Wendy Ide, Kevin Eason, Geoff Brown, Gerald Davies, Sam Lister, Andrew Norfolk, David Sharrock, Alastair James, Ben Webster Transport Correspondent, Mrs Moneybags, Anne Spackman Property Editor, John Farrow, Jennai Cox Fitness Editor, Angus MacLeod Scottish Political Correspondent, Tim Reid and David Sharrock, Anthony Browne, Debra Craine, Rory Watson, R. E. Chorley, Gary Jacob, Joe Morgan, Jill Dupleix, Ruth Gledhill Religion Correspondent, Dan Sabbagh, Jonathan Gornall, Jeremy Hunt, Nick Robinson, Alan Hamilton, Andy Stephens, Brian Webb, Roland Watson, Richard Lloyd Parry, David Hands, Trefor Vaughan, Ron Lewis, David Charter, Jeremy Plester, Derwent May, Patience Wheatcroft Business Editor, Hugo Rifkind, Angela Jameson, Susan Emmett, Russell Kempson, John Price, Jill Ely, Mary Gold, Jeremy Woolf, Steve Bird and James Hlder, Sarah Vine, John Westerby, Martyn Halle, Rick Broadbent, Tom Baldwin, Stephen Burgen, Jill Sherman Whitehall Editor, Philip Manasseh, Ann Treneman, Simon de Bruxelles, Gabriel Rozenberg, Zahid Hussain and Roland Watson, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, Marcus Binney, Raymond Keene, Vaughan Freeman, Ian Evans, Leslie Felperin, Richard Miles Investment Editor, Matt Dickinson, Ernest Sykes, Robert Galster, Rosemary Bennett Deputy Political Editor, Carl Mortished International business Editor, Nigel Hawkes, Jeremy Page, John Hayward, Angela Jameson Industry Correspondent, Chris Campling, Russell Hotten, Cathy Harris, Jill Sherman, Richard Owen, Rachael Hitchinson, Christopher Martin-Jenkins Chief Cricket Correspondent, Oliver August, Peter Dixon, Nick Hasell, Tom Baldwin and Philip Webster, Catriona Gallacher, David Hands Rugby Correspondent, Tom Dart, Valerie Elliot Countryside Editor, Glen Owen, Sujit Bhattacharjee, Adam Fresco, John Allison, Steve Jelbert, Nick Szczepanik, Mary Ann Sieghart, Philip Webster Political Editor, Brian MacArthur, Alan Gillott, Stephen Leslie, Ian Johns, Graham Searjeant Financial Editor, Terry Sanderson, Simon Taylor, Nicky Baker, Chris McGrath, Bonnie Prince Billy, Russell Jenkins, Caitlin Moran, Bronwen Maddox Foreign Editor's, Peter Riddell, Solomon Wariso, Norman Bacrac, David Charter Chief Political Correspondent, Ian Whittell, David Sinclair, Simon Jenkins, Gary Duncan Economics Correspondent, Mark Henderson, Martin Waller, Michael Horsnell, Clarice Moran, Lisa Verrico, Nigel Hawkes Health Editor, Sarah Butler, Ashling O'Connor, Benedict Nightingale, Richard Ford Home Correspondent and Daniel McGrory, Rob Green, Daniel Rosenthal, Stuart Birch, Stephen Dalton, David Yelland, Nicola Woolcock, Leo Lewis, Richard Morrison, James Christopher, Denis R. Alexander, Matthew Connolly, Alan Lee Racing Correspondent, Owen Slot, Barry Hyman, Jenny Davey, Rev John Hartley, Richard Ford, Christopher Irvine, Damian Barr, Jayne Dowle,
... error Scotland again Matthew prevails Armstrong's loss Zhang's invite Earth moves for Nicholls as he ... On Uk Living Sbc Touching the Voice Interview Ren?e Fleming Tells Matthew Connolly why She Has ...
2004 - Gale Group | TDA
Xue Liu, Clément Gallay, Morten Kjos, Arnau Domenech, Jelle Slager, Sebastiaan P. van Kessel, Kèvin Knoops, Robin A. Sorg, Jing‐Ren Zhang, Jan‐Willem Veening,
... Search for more papers by this author Jing-Ren Zhang Jing-Ren Zhang orcid.org/0000-0003-4973-4243 Center for ... Search for more papers by this author Jing-Ren Zhang Jing-Ren Zhang orcid.org/0000-0003-4973-4243 Center for ...
Tópico(s): Pneumonia and Respiratory Infections
2017 - Springer Nature | Molecular Systems Biology
Hong-Fei Zhang, Shan Gao, Zhang Benren, Ting-Chuan Luo, W. Lin,
... by this author on: GSW Google Scholar Ben-Ren Zhang; Ben-Ren Zhang 1Department of Geochemistry, China University of Geosciences, Wuhan ... Wuhan 430074, People's Republic of China Ben-Ren Zhang 1Department of Geochemistry, China University of Geosciences, Wuhan ... Site Citation Hong-Fei Zhang, Shan Gao, Ben-Ren Zhang, Ting-Chuan Luo, Wen-Li Lin; Pb isotopes ...
Tópico(s): earthquake and tectonic studies
1997 - Geological Society of America | Geology
Weidong Sun, Shuguang Li, Hong-Fei Zhang, Shan Gao, Zhang Benren, Ting-Chuan Luo, Wenli Ling,
... by this author on: GSW Google Scholar Ben-Ren Zhang; Ben-Ren Zhang 2Department of Geochemistry, China University of Geosciences, Wuhan ... Wuhan 430074, People's Republic of China Ben-Ren Zhang 2Department of Geochemistry, China University of Geosciences, Wuhan ... Shuguang Li, Hong-Fei Zhang, Shan Gao, Ben-Ren Zhang, Ting-Chuan Luo, Wen-Li Ling; Pb isotopes ...
Tópico(s): earthquake and tectonic studies
1998 - Geological Society of America | Geology
Xiaofeng Shan, Furen Zhang, Hongqing Tian, Na Wang, Shengji Zhou, Guangjin Wang,
... Jinan, ChinaSearch for more papers by this authorFu-Ren Zhang MD, PhD, Fu-Ren Zhang MD, PhD [email protected] Shandong Clinical College of ... Jinan, ChinaSearch for more papers by this authorFu-Ren Zhang MD, PhD, Fu-Ren Zhang MD, PhD [email protected] Shandong Clinical College of ...
Tópico(s): Nail Diseases and Treatments
2015 - Wiley | International Journal of Dermatology
Zhongdi Song, Lei Chen, Jiangxin Wang, Yinhua Lü, Weihong Jiang, Weiwen Zhang,
... Wang J. Chen L. Tian X. Huang S. Ren X. Zhang W. Quantitative iTRAQ LC-MS/MS proteomics reveals ... Wang J. Chen L. Tian X. Huang S. Ren X. Zhang W. Quantitative iTRAQ LC-MS/MS proteomics reveals ... Wang J. Chen L. Tian X. Huang S. Ren X. Zhang W. Quantitative iTRAQ LC-MS/MS proteomics reveals ... Wang J. Chen L. Tian X. Huang S. Ren X. Zhang W. Quantitative iTRAQ LC-MS/MS proteomics reveals ... Wang J. Chen L. Tian X. Huang S. Ren X. Zhang W. Quantitative iTRAQ LC-MS/MS proteomics reveals ... Wang J. Chen L. Tian X. Huang S. Ren X. Zhang W. Quantitative iTRAQ LC-MS/MS proteomics reveals ...
Tópico(s): Photosynthetic Processes and Mechanisms
2014 - Elsevier BV | Molecular & Cellular Proteomics
Xue Jun Zhang, Wei Huang, Sen Yang, Liang Dan Sun, Fengyu Zhang, Qi Xing Zhu, Fu Ren Zhang, Chi Zhang, Wen Hui Du, Xingmao Pu, Hui Li, Feng Li Xiao, Zai Xing Wang, Yong Cui, Hao Fei, Jie Zheng, Xue Yang, Hui Cheng, Chun He, Xiao Ming Liu, Li Min Xu, Hou Feng Zheng, Shu Mei Zhang, Jianzhong Zhang, Hong Yan Wang, Yi Lin Cheng, Bi Hua Ji, Qiao Yun Fang, Yu Zhen Li, Fu Sheng Zhou, Jian Wen Han, Cheng Quan, Bin Chen, Jun Lin Liu, Da Lin, Li Fan, An Ping Zhang, Sheng Xiu Liu, Chun Jun Yang, Pei Guang Wang, Wen Ming Zhou, Guo Shu Lin, Wei Dong Wu, Xing Fan, Min Gao, Bao Qi Yang, Wen Sheng Lu, Zheng Zhang, Kunju Zhu, Song Ke Shen, Min Li, Xiao Yan Zhang, Ting Ting Cao, Wei Ren, Xin Zhang, Jun He, Xian Fa Tang, Shun Lu, Jian Qiang Yang, Lin Zhang, Dan Ni Wang, Feng Yuan, Xianyong Yin, Hong Jie Huang, Hai Feng Wang, Xin Yi Lin, Jianjun Liu,
Tópico(s): Dermatology and Skin Diseases
2009 - Nature Portfolio | Nature Genetics
Kanako Tamura, Norihiko Ohbayashi, Koutaro Ishibashi, Mitsunori Fukuda,
... 19Wang F. Zhang H. Zhang X. Wang Y. Ren F. Zhang X. Zhai Y. Chang Z. Biochem. Biophys. Res. ... 19Wang F. Zhang H. Zhang X. Wang Y. Ren F. Zhang X. Zhai Y. Chang Z. Biochem. Biophys. Res. ... 19Wang F. Zhang H. Zhang X. Wang Y. Ren F. Zhang X. Zhai Y. Chang Z. Biochem. Biophys. Res. ... 19Wang F. Zhang H. Zhang X. Wang Y. Ren F. Zhang X. Zhai Y. Chang Z. Biochem. Biophys. Res. ...
Tópico(s): RNA regulation and disease
2010 - Elsevier BV | Journal of Biological Chemistry
Qingyang Zhang, Daniel Wai‐Hung Ho, Yu‐Man Tsui, Irene Oi‐Lin Ng,
... expression genes.8Wang X. He Y. Zhang Q. Ren X. Zhang Z. Direct comparative analyses of 10X Genomics Chromium ... A.B. Pflanz S. Liu K. Peng J. Ren X. Zhang Z. Landscape and dynamics of single immune cells ... A.B. Pflanz S. Liu K. Peng J. Ren X. Zhang Z. Landscape and dynamics of single immune cells ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2022 - Elsevier BV | Cellular and Molecular Gastroenterology and Hepatology
Yihu Yang, Yong‐Liang Jiang, Juan Zhang, Lei Wang, Xiaohui Bai, Shijie Zhang, Yan-Min Ren, Na Li, Yonghui Zhang, Zhiyong Zhang, Qingguo Gong, Yide Mei, Ting Xue, Jing-Ren Zhang, Yuxing Chen, Cong‐Zhao Zhou,
Staphylococcus aureus, a Gram-positive bacterium causes a number of devastating human diseases, such as infective endocarditis, osteomyelitis, septic arthritis and sepsis. S. aureus SraP, a surface-exposed serine-rich repeat glycoprotein (SRRP), is required for the pathogenesis of human infective endocarditis via its ligand-binding region (BR) adhering to human platelets. It remains unclear how SraP interacts with human host. Here we report the 2.05 Å crystal structure of the BR of SraP, revealing ...
Tópico(s): Peptidase Inhibition and Analysis
2014 - Public Library of Science | PLoS Pathogens
The frequencies of occurrence of four bases in the first, second and third codon positions and in the total coding sequences have been calculated by the codon usage table published in 1990 by Ikemura et al. The distribution of frequencies are further analysed in detail by a graphic technique presented recently by us. Formulas expressing the frequencies of four bases in the first and second codon positions in terms of frequencies of amino acids have been given. It is shown by the graphic analysis ...
Tópico(s): Fractal and DNA sequence analysis
1991 - Oxford University Press | Nucleic Acids Research
Abstract A content-balancing accuracy index, called q 9, to evaluate gene-finding algorithms has been proposed. Here the concept of content-balancing means that the evaluation by this index is independent of the coding and non-coding composition of the sequence being evaluated. Since the coding and non-coding compositions are severely unbalanced in eukaryotic genomes, the performance of gene-finding algorithms is either over- or under-evaluated by the widely used accuracy indices, e.g., the correlation ...
Tópico(s): Genomics and Phylogenetic Studies
2002 - Taylor & Francis | Journal of Biomolecular Structure and Dynamics
Chun‐Ting Zhang, Ren Zhang, Hong‐Yu Ou,
Abstract Motivation: Genome projects for many prokaryotic and eukaryotic species have been completed and more new genome projects are being underway currently. The availability of a large number of genomic sequences for researchers creates a need to find graphic tools to study genomes in a perceivable form. The Z curve is one of such tools available for visualizing genomes. The Z curve is a unique three-dimensional curve representation for a given DNA sequence in the sense that each can be uniquely ...
Tópico(s): Genomics and Phylogenetic Studies
2003 - Oxford University Press | Bioinformatics
The distribution of the G+C content in the mouse genome has been studied using a windowless technique. We have found that: (i) Abrupt variations of the G+C content from a GC-rich region to a GC-poor region, and vice versa, occur frequently at some sites along the sequence of the mouse genome. (ii) Long domains with relatively homogeneous G+C content (isochores) exist, which usually have sharp boundaries. Consequently, 28 isochores longer than 1 Mb have been identified in the mouse genome. A homogeneity ...
Tópico(s): Genomics and Phylogenetic Studies
2003 - Elsevier BV | Genomics
Tópico(s): Machine Learning in Bioinformatics
2003 - Elsevier BV | Gene
Guang Chen, Fa-Ren Zhang, Ren Jiang, Lihua Tao, Zhong‐Ying Shen, Zhuo Lv, Shijiang Yu, Bingfei Dong, Li–Yan Xu, En‐Min Li,
Tópico(s): Cell Adhesion Molecules Research
2008 - Springer Science+Business Media | Journal of Cancer Research and Clinical Oncology
Essential genes are the genes that are indispensable for the survival of an organism. The genome-scale identification of essential genes has been performed in various organisms, and we consequently constructed DEG, a Database that contains currently available essential genes. Here we analyzed functional distributions of essential genes in DEG, and found that some essential-gene functions are even conserved between the prokaryote (bacteria) and the eukaryote (yeast), e.g., genes involved in information ...
Tópico(s): Machine Learning in Bioinformatics
2008 - Springer Science+Business Media | Methods in molecular biology
Xiaoping Li, Rui Gan, Pengli Li, Yuanyuan Ma, Liwen Zhang, Ren Zhang, Yong Wang, Ning Ning Wang,
Tópico(s): Photosynthetic Processes and Mechanisms
2006 - Springer Science+Business Media | Plant Molecular Biology
Tópico(s): Vibrio bacteria research studies
2004 - Nature Portfolio | Nature Biotechnology
Let a, c, g and t denote the occurrence frequencies of A, C, G and T, respectively, in a genome. We calculated the statistical quantity S=a2+c2+g2+t2 for each of 809 genomes (11 archaea, 42 bacteria, 3 eukaryota, 90 phages, 36 viroids and 627 viruses) and 236 plasmids. We found that S<1/3 is strictly valid for almost all of the above genomes or plasmids. As a direct deduction of the above observation, it is shown that (i) the statistical quantity S is a kind of genome order index, which is negatively ...
Tópico(s): Genomics and Phylogenetic Studies
2004 - Elsevier BV | Computational Biology and Chemistry
Hao Luo, Yan Lin, Feng Gao, Chun-Ting Zhang, Ren Zhang,
The combination of high-density transposon-mediated mutagenesis and high-throughput sequencing has led to significant advancements in research on essential genes, resulting in a dramatic increase in the number of identified prokaryotic essential genes under diverse conditions and a revised essential-gene concept that includes all essential genomic elements, rather than focusing on protein-coding genes only. DEG 10, a new release of the Database of Essential Genes (available at http://www.essentialgene. ...
Tópico(s): Bacterial Genetics and Biotechnology
2013 - Oxford University Press | Nucleic Acids Research
Peng Zhang, Ren Zhang, Mingxia Gao, Xiangmin Zhang,
The capture and detection of circulating tumor cells (CTCs) in the bloodstream of patients with cancer is crucial for the clinical diagnosis and therapy. In the present work, a facile and integrated approach based on novel nitrocellulose membrane substrate and large-scale surface-enhanced Raman scattering (SERS) imaging technology has been developed for CTCs' sensitive detection and enumeration. The system mainly consists of three aspects: capture of CTCs in bloodstream, SERS probes labeling of the ...
Tópico(s): Microfluidic and Bio-sensing Technologies
2013 - American Chemical Society | ACS Applied Materials & Interfaces
Chao Zhang, Feng Gao, Hao Luo, Chun-Ting Zhang, Ren Zhang,
As a first-line diabetes drug that is widely prescribed around the world, metformin has been demonstrated to be effective in reducing microvascular risk, in addition to lowering glucose levels. Specifically, metformin use has been shown to be associated with improved lipid profiles, such as increased levels of high-density lipoprotein cholesterol (HDL-C). However, no study has been performed to examine the differential response in HDL-C levels to metformin treatment by race/ethnicity. Here, based ...
Tópico(s): Diabetes Treatment and Management
2015 - BioMed Central | Cardiovascular Diabetology
Feng Gao, Hao Luo, Chun‐Ting Zhang, Ren Zhang,
The database of essential genes (DEG, available at http://www.essentialgene.org), constructed in 2003, has been timely updated to harbor essential-gene records of bacteria, archaea, and eukaryotes. DEG 10, the current release, includes not only essential protein-coding genes determined by genome-wide gene essentiality screens but also essential noncoding RNAs, promoters, regulatory sequences, and replication origins. Therefore, DEG 10 includes essential genomic elements under different conditions ...
Tópico(s): RNA and protein synthesis mechanisms
2015 - Springer Science+Business Media | Methods in molecular biology
Ling Zhang, Ren Zhang, Mingxia Gao, Xiangmin Zhang,
Tópico(s): Spectroscopy Techniques in Biomedical and Chemical Research
2016 - Elsevier BV | Talanta
Fuquan Yang, Tianyou Zhang, Ren Zhang, Yoichiro Ito,
Analytical high-speed counter-current chromatography (HSCCC) was used for the systematic selection and optimization of the two-phase solvent system to separate alkaloids from Coptis chinensis Franch. The optimum solvent system thus obtained led to the successful separation of alkaloids from C. chinensis Franch by preparative HSCCC. One batch separation yielded four pure alkaloids, including palmatine, berberine, epiberberine and coptisine from the crude alkaloid extract.
Tópico(s): Phytochemical Studies and Bioactivities
1998 - Elsevier BV | Journal of Chromatography A
Xihui Gao, Qi Yue, Zining Liu, Mengjing Ke, Xingyu Zhou, Sihan Li, Jianping Zhang, Ren Zhang, Liang Chen, Ying Mao, Cong Li,
Surgical resection is a mainstay in the treatment of malignant brain tumors. Surgeons, however, face great challenges in distinguishing tumor margins due to their infiltrated nature. Here, a pair of gold nanoprobes that enter a brain tumor by crossing the blood-brain barrier is developed. The acidic tumor environment triggers their assembly with the concomitant activation of both magnetic resonance (MR) and surface-enhanced resonance Raman spectroscopy (SERRS) signals. While the bulky aggregates continuously ...
Tópico(s): Lanthanide and Transition Metal Complexes
2017 - | Advanced Materials
Lin Chen, Shaodong Zhang, Ren Zhang, Jinguang Li, Penghui Yang, Jiaying Pan, Haiqiao Wei,
Recently the turbulent jet ignition (TJI) configured by pre-chamber has been paid more attention as it can effectively achieve rapid combustion thus high thermal efficiency. In this work, using a single-cylinder optical engine with high compression ratios, the effects of turbulent jet ignition on lean burning and engine knocking were comprehensively investigated, with the conventional spark-ignition scenarios for comparisons. The results show that the pre-chamber with larger volume results in stronger ...
Tópico(s): Combustion and Detonation Processes
2021 - Elsevier BV | Fuel
Zhiyao Fu, Hyunbae Kim, Paul T. Morse, Mu‐Jie Lu, Maik Hüttemann, Xiaolu A. Cambronne, Kezhong Zhang, Ren Zhang,
Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism and energy production. NAD+-dependent deacetylase sirtuin 3 (SIRT3) regulates the acetylation levels of mitochondrial proteins that are involved in mitochondrial homeostasis. Fasting up-regulates hepatic SIRT3 activity, which requires mitochondrial NAD+. What is the mechanism, then, to transport more NAD+ into mitochondria to sustain enhanced SIRT3 activity during fasting?SLC25A51 is a recently discovered mitochondrial NAD+ ...
Tópico(s): Biochemical effects in animals
2022 - Elsevier BV | Metabolism
Lin Chen, Xiǎo Zhang, Ren Zhang, Jinguang Li, Jiaying Pan, Haiqiao Wei,
In traffic transportation, the use of low-carbon fuels is the key to being carbon-neutral. Hydrogen-enhanced natural gas gets more and more attention, but practical engines fueled with it often suffer from low engine power output. In this study, the inner mechanism of hydrogen direct injection on methane combustion was optically studied based on a dual-fuel supply system. Simultaneous pressure acquisition and high-speed direct photography were used to analyze engine performance and flame characteristics. ...
Tópico(s): Biodiesel Production and Applications
2022 - Elsevier BV | International Journal of Hydrogen Energy