Capítulo de livro

Molecular Interaction Between the Third Complement Protein and Bacterial Cell-Surface Macromolecules

1985; Springer Nature; Linguagem: Inglês

10.1007/978-3-642-70351-5_10

ISSN

0067-4672

Autores

R. P. Levine,

Tópico(s)

Blood groups and transfusion

Resumo

When C3, the third complement protein, is activated it can bind covalently to bacterial cell-surface macromolecules where its presence can lead to cell death by either phagocytosis or cytolysis. Haemophilus influenzae type B, 018:K1 Escherichia coli and group A streptococci are three examples of complement resistant pathogens and this paper describes certain features of the chemistry of C3 activities and binding that relate to the resistance of these organisms to be bactericidal effects of complement.

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