Artigo Revisado por pares

Utilización de analgésicos opioides mayores en dos áreas sanitarias de España durante 2005

2009; Elsevier BV; Volume: 16; Issue: 2 Linguagem: Inglês

ISSN

2340-3292

Autores

O. Larrubia Muñoz, Esperanza Escortell Mayor, J. Canal Sotelo, R. Martínez Martínez, N. Plana Farras, E. Barallat Gimeno, A. Valdivia Perez, C. Esteban Carlero,

Tópico(s)

Poisoning and overdose treatments

Resumo

Objective: to compare and to describe the prescription of strong opioid analgesics in two sanitary districts of Spain during 2005. Method: Design: an ecological descriptive study. Setting: Lleida Health Service and the Third Sanitary District in Madrid (3D-Madrid) Community. Main outcome measures: a primary healthcare database supplied information regarding the prescription of strong opioids. We used the ATC/DDD (Anathomical-Therapeutical-Clinical/Defined Daily Dose) drug classification. Data obtained are expressed as Defined Daily Dose per 1,000,000 inhabitants per day (DHD). Results: DHDs of 3,690 for Lleida and of 2,140 for the Third Sanitary District in Madrid (3D-Madrid) were found. Fentanyl constitutes 88 percent of prescribed opioids in 3D-Madrid versus 52 percent in Lleida. Buprenorphine represents 44 percent of prescribed opioids in Lleida versus 4 percent in 3D-Madrid. Conclusions: morphine has been substituted for by other drugs, mainly the transdermic forms of fentanyl and buprenorphine.

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