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Better Outcomes for Our Patients: Moving Science Forward in the Biomolecular Core Laboratory at the Nemours Center of Pediatric Research

2011; Association of Biomolecular Resource Facilities; Volume: 22; Linguagem: Inglês

1943-4731

D.L. Stabley, E.C. Hitchens, Priscila Geller, K. Sol-Church, Janet T. Holbrook,

Biomedical and Engineering Education

Nemours Biomedical Research has a long-standing commitment to scholarly and scientific endeavors directed towards improving the diagnosis and treatment of pediatric medical conditions. Established in 2004 with the support of a COBRE grant from the NIH s National Center for Research Resources, the Nemours Center for Pediatric Research provides clinical and translational researchers with the tools as well as training they need to perform their research. The Biomolecular Core Laboratory (BCL), located at the Alfred I. duPont Hospital for Children in Wilmington, Delaware, is supported by the Center of Pediatric Research. We provide a unique opportunity for Nemours clinicians, research staff, and affiliates at University of Delaware and Thomas Jefferson University to develop competitive research projects in genetics as well as provide essential services in molecular biology and genomics. The mission of the BCL is to facilitate, through state-of-the-arts services and stewardship, discoveries that begin at a molecular level and move rapidly from patient-oriented research to the bedside. Working in close collaboration with those engaged in research activities, our goal is to enable fast, effective and productive top quality services as well as to match BCL s strengths with our clients needs. This poster highlights the services the Biomolecular Core lab offers, including molecular biology training, a listing of our instrumentation, and core businesses including DNA sequencing, genotyping, gene expression and methylation analysis. We will also highlight our newly established microarray service utilizing the Affymetrix Microarray platform. The development of this vital core allowed investigators, who previously used extramural services and technologies, to move those projects in house, thus saving both time and money for our clients.