Portal de Periódicos da CAPES

ON THE UTILIZATION OF GLYCINE FOR URIC ACID SYNTHESIS IN MAN

1947; Elsevier BV; Volume: 167; Issue: 3 Linguagem: Inglês

10.1016/s0021-9258(17)30976-6

1083-351X

David Shemin, D. Rittenberg,

thermodynamics and calorimetric analyses

Sonne et a1.l and Buchanan and Sonne2 have recently reported on the origin of the carbon atoms of uric acid in the pigeon.They find that glycine or a metabolic derivative is probably the precursor of carbon atom 4 of uric acid.In experiments already reported3 we fed glycine labeled sith N16 to a male human adult; uric acid was isolated from 24 hour urine 66 gm. of glycine containing 32.4 atom per cent Nr6 excess were fed to amale human adult for 3 days and urinary uric acid isolated on subsequent days.