The Physiology of the Normal Synovium
1980; Elsevier BV; Linguagem: Inglês
10.1016/b978-0-12-655102-0.50013-8
Autores Tópico(s)Veterinary Equine Medical Research
ResumoThis chapter discusses the physiology of the normal human joints. The joint cavity, like other hollow organs such as the urinary bladder and the aorta, follows the pressure–volume relationship of a rubber balloon. Such relationships follow the laws of elastomeric theory. The soft tissues around the rheumatoid knee are found to be stiffer than those of the normal knee, and the pressure change per unit volume of effusion (joint compliance) is considerably greater in rheumatoid than in normal knees. The intraarticular pressure (IAP) in the normal knee at rest is clearly subatmospheric and with quadriceps contraction it becomes markedly negative. The inverse relationship between high IAP and synovial fluid glucose concentration was pointed out by Ropes and Bauer who suggested that glucose diffusion into the joint was impaired by blood vessel compression.
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