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Evaluation of an Online Platform for Cancer Patient Self-reporting of Chemotherapy Toxicities

2007; Oxford University Press; Volume: 14; Issue: 3 Linguagem: Inglês

10.1197/jamia.m2177

1527-974X

Ethan Basch, David Artz, Alexia Iasonos, John Speakman, Kristen Shannon, Kevin Lin, Conrad D. Pun, Hua‐Hie Yong, Paul Fearn, Allison Barz Leahy, Howard I. Scher, Mary S. McCabe, Deborah Schrag,

Childhood Cancer Survivors' Quality of Life

The current mechanism for monitoring toxicity symptoms in cancer trials depends on a complex paper-based process. Electronic collection of patient-reported outcomes (PROs) may be more efficient and accurate. An online PRO platform was created including a simple data entry interface, real-time report generation, and an alert system to e-mail clinicians when patients self-report serious toxicities. Feasibility assessment involving 180 chemotherapy patients demonstrated high levels of use at up to 40 follow-up clinic visits per patient over 16 months (85% of patients at any given visit), with high levels of patient and clinician acceptance and satisfaction (>95%). Alerts were used as the basis for delayed chemotherapy treatments, dose modifications, and scheduling changes. These results demonstrate that online patient-reporting is a feasible strategy for chemotherapy toxicity symptom monitoring, and may improve safety and satisfaction with care. Ongoing multi-center research will evaluate the impact of this approach on clinical and administrative outcomes.