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Antibody-Independent Mechanisms in the Development of Acquired Immunity to Malaria

1983; Springer Nature; Linguagem: Inglês

10.1007/978-1-4684-4481-0_37

2214-8019

William P. Weidanz, James L. Grun,

Invertebrate Immune Response Mechanisms

The plasmodia are hemoprotozoan parasites which cause malaria in a variety of animal species, including man. Infection with these parasites stimulates acquired immune responses which are directed primarily against blood stages and, when successful, bring about a reduction in the number of circulating plasmodia and/or protect the host against reinfection with homologous parasites (1,2). While the actual mechanisms of resistance are ill-defined, it appears that immunity to malaria requires the participation of both T and B lymphocyte systems.