Capítulo de livro Revisado por pares

Chapter 5 Molecular biology of bacterial septation

1994; Elsevier BV; Linguagem: Inglês

10.1016/s0167-7306(08)60408-1

ISSN

1875-7901

Autores

Juan A. Ayala, Teresa Garrido, Miguel A. de Pedro, Miguel Vicente,

Tópico(s)

RNA and protein synthesis mechanisms

Resumo

This chapter discusses the molecular biology of bacterial septation. Bacterial division has been studied for many years. Three conclusions are sufficient to introduce the topic of this chapter: (1) bacterial division is very well regulated in time and in space; (2) division is a discontinuous event in topography and chronology; and (3) bacterial cells divide as a consequence of continuous growth. Many advances in the knowledge of division controls are derived from studies on unicellular organisms as yeasts. Cell division in eukaryotic cells includes the partition of two structures, the nucleus and the cytoplasm. In bacteria, the nucleoid divides after replication by segregation, a simpler mechanism. Morphological events during the cell division cycle in prokaryotes and eukaryotes are similar. Growth induces a discontinuous event that leads to the initiation of DNA replication; this is one of the several transitions which regulate the exit from one cell cycle stage and the entrance into the next one. The molecular mechanisms which signal some transition points are well described for the cell cycles of bakers and fission yeasts.

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