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Successful treatment of severe gastrointestinal manifestations of Henoch-Schonlein Purpura and factor XIII deficiency using cryoprecipitate transfusion

2015; Elsevier BV; Volume: 2; Issue: 2 Linguagem: Inglês

10.1016/j.ijpam.2015.06.003

2352-6467

Abdullah Al Sonbul, Abdullah Noor, Naser M. Ahmed, Norah Al-Mutairi, Asma Jokhadar, Munira Al-Marri, Suliman Al-Mayouf,

Vasculitis and related conditions

Henoch-Schonlein Purpura (HSP) might present with severe gastrointestinal (GI) involvement. Herein, we report 3 cases of HSP with severe GI manifestations in the form of hematemesis, melena, pancreatitis, and erosive gastritis. Different treatment modalities were not successful. Low factor XIII levels were found in all patients and Cryoprecipitate transfusion resulted in significant immediate clinical improvement.