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Double-Stranded Viral RNA

1969; Elsevier BV; Linguagem: Inglês

10.1016/s0065-3527(08)60874-x

1557-8399

R.K. Ralph,

RNA and protein synthesis mechanisms

The pace of research on RNA virus replication and the huge amount of related literature that has accumulated in the past 6 years attest to the wide interest in the topic. There has also been some controversy and apparent confusion, probably largely because of pressure for publication priority. In this chapter, methods for detecting, isolating, and characterizing double-stranded viral RNA are reviewed and recent results related to the isolation, identification, and replication of double-stranded RNA's in animal, plant, insect, and bacterial systems are discussed in the broad context of RNA virus replication. This chapter discusses each virus separately since this emphasizes more clearly on what is in fact established for a particular virus and what is inferred from other systems. Since much of the work on RNA phage replication prior to 1968 is being reviewed by Knolle and Franklin (this series), and is discussed in several earlier articles. Only certain aspects of RNA phage replication are considered in the chapter. Some properties of the viruses discussed in this chapter are summarized in a table.