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HYDROXYZINE IN THE TREATMENT OF INTERSTITIAL CYSTITIS

1994; Elsevier BV; Volume: 21; Issue: 1 Linguagem: Inglês

10.1016/s0094-0143(21)00600-5

1558-318X

Theoharis C. Theoharides,

Allergic Rhinitis and Sensitization

Hydroxyzine is a piperazine, tricyclic, H1-receptor antagonist with unique properties, especially the inhibition of mast cell and neuronal secretion. Preliminary results indicate is has an unusual ability to reduce interstitial cystitis symptoms. The long history, lack of major side effects, wide availability, low cost, and apparent effectiveness of hydroxyzine compel presentation of these preliminary results.