Produção Nacional
Clinical effectiveness of lidocaine and benzocaine for topical anesthesia.
1999; National Institutes of Health; Volume: 46; Issue: 3 Linguagem: Inglês
Autores
Adalberto Luiz Rosa, Cássio Edvard Sverzut, Samuel Porfírio Xavier, M A Lavrador,
Tópico(s)Anesthesia and Pain Management
ResumoThe effectiveness of lidocaine and benzocaine in reducing pain produced by needle insertion into the palate was evaluated in a double-blind and placebo-controlled study using a more suitable method. Twenty subjects, 10 men and 10 women, submitted to 4 sessions in which they were randomly treated with 5% lidocaine, a placebo that tasted like lidocaine, 20% benzocaine, and a placebo that tasted like benzocaine. At each session, a 27-gauge needle was inserted into the palate twice, once before (baseline) and once after drug application for 1 minute. Immediately after each insertion, subjects indicated on a visual analog scale the pain intensity perceived. Lidocaine and benzocaine were equally efficient, and both were better than placebo in reducing pain caused by insertion of needles into the palate.
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