Prenylated xanthonoids from Calophyllum apetalum
1997; Elsevier BV; Volume: 46; Issue: 8 Linguagem: Inglês
10.1016/s0031-9422(97)00507-4
ISSN1873-3700
AutoresMunekazu Iinuma, Tetsuro Ito, Hideki Tosa, Toŝhiyuki Tanaka, Ryoko Miyake, Veliah Chelladurai,
Tópico(s)Bioactive natural compounds
ResumoThree new xanthonoids, apetalinones A-C, were isolated from the roots of Calophyllum apetalum, as well as the known compounds, calozeyloxanthone and zeyloxanthonone. The stem bark of this species yielded a new xanthonoid, apetalinone D, and another known xanthonoid, tomentonone. Five known xanthones (3,8-dihydroxy-1,2-dimethoxy-, 1,3-dihydroxy-2,5-dimethoxy-, 1,5-dihydroxy-, 1,3,5-trihydroxy-2-methoxy- and 1,3,5-trihydroxyxanthone) and two flavonoids ((−)-epiafzelechin and (−)-epicatechin) were also characterized as constituents in the stem wood. Among them, apetalinone A was a novel xanthone with 1,1-dimethylallyl ether moiety, which indicated a new biosynthetic pathway including Claisen rearrangement and Diels-Alder reaction.
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