Lipoprotein lipase: physiology, biochemistry, and molecular biology
2001; Frontiers in Bioscience; Volume: 6; Issue: 1 Linguagem: Inglês
10.2741/goldberg
ISSN1094-3935
Autores Tópico(s)Lipid metabolism and biosynthesis
ResumoLipoprotein lipase (LpL) is the primary enzyme responsible for conversion of lipoprotein triglyceride into free fatty acids and monoglyderides. This permits their uptake into muscle and adipose. The roles of this enzyme in normal and altered physiology are reviewed. In addition, the relationship of LpL activity and genetic variations of LpL and human disease are summarized.
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