Vaccination against hepatitis B in homosexual men
1989; Elsevier BV; Volume: 87; Issue: 3 Linguagem: Inglês
10.1016/0002-9343(89)90526-3
ISSN1555-7162
Autores Tópico(s)Hepatitis C virus research
ResumoAbstract Homosexual men are at increased risk for infection with hepatitis B virus (HBV). Both plasma-derived and recombinant deoxyribonucleic acid vaccines have been shown to induce long-standing protective immunity in this population. However, non-responders and weak responders to HBV vaccine have recently become a problem among homosexual men because of an impaired antibody response due to previous infection with human immunodeficiency virus. In addition, human immunodeficiency virus infection predisposes persons to the development of a HBV carrier state following HBV infection. Vaccination still remains the most effective tool for preventing hepatitis B in homosexual men, although recent behavioral changes have apparently resulted in a decreased incidence of HBV infection among this group.
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