Preparation of Tyrosol and 4-Methoxyphenethyl Alcohol.
1963; Pharmaceutical Society of Japan; Volume: 11; Issue: 2 Linguagem: Inglês
10.1248/cpb.11.258
ISSN1347-5223
AutoresShun‐ichi Yamada, Tozo Fujii, Keijiro Takagi, Yasuo Gomi, Seishi Matsushita,
Tópico(s)Chemical Synthesis and Reactions
ResumoTyrosol (V) and 4-methoxyphenethyl alcohol (X) were prepared from the corresponding amines (I and VI) in good yield. The steps involved are formation of the acetamides (II and VII), N-nitrosoamides (III and VIII), and acetic esters (IV and IX) by application of the White's method, and hydrolysis of the resultant esters to form the alcohols (V and X).
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