Artigo Produção Nacional

Estudo duplo-cego e randomizado do peeling de ácido retinoico a 5% e 10% no tratamento do melasma: avaliação clínica e impacto na qualidade de vida

2011; Sociedade Brasileira de Dermatologia; Volume: 3; Issue: 1 Linguagem: Inglês

ISSN

1984-8773

Autores

Geraldo Magela Magalhães, Maria de Fátima Borges, Aline Raissa de Carvalho Queiroz, Ana Carolina Dias Viana de Andrade, Sabrina Veloso Pedrosa, Michelle dos Santos Diniz,

Tópico(s)

Acne and Rosacea Treatments and Effects

Resumo

Introduction: Melasma is a highly prevalent dermatosis that greatly affects patients' quality of life and is challenging to treat.The Melasma Area and Severity Index and the Melasma Quality of Life Scale are useful tools in the clinical and impact on quality of life evaluations, respectively. Objective: To compare the effects of 5% and 10% retinoic acid peels in patients with melasma, using the Melasma Area and Severity Index and the Melasma Quality of Life Scale to evaluate the clinical and quality of life impacts, respectively . Methods: Patients (n = 30) were randomized to receive either 5% or 10% retinoic acid peels in weeks 0, 2, 4 and 6 of the treatment. Clinical and quality of life evaluations took place in weeks 0 and 8. Results: In a global evaluation of the two groups, there was a statistically significant improvement in scores from baseline to week 8, yet there were no statistically significant differences between treatment groups. Conclusions: Retinoic acid peels are effective and safe, as an isolated therapy, in the treatment of melasma.There is no difference in treatment results between 5% and 10% concentrations

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