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The Reduction of Baseline Serotonin 2A Receptors in Mild Cognitive Impairment is Stable at Two-year Follow-up

2011; IOS Press; Volume: 23; Issue: 3 Linguagem: Inglês

10.3233/jad-2010-100903

1875-8908

Lisbeth Marner, Gitte M. Knudsen, Karine Madsen, Søren Holm, William F.C. Baaré, Steen Gregers Hasselbalch,

Treatment of Major Depression

We previously demonstrated a 20–30% reduction in cortical 5-HT2A receptor binding in patients with mild cognitive impairment (MCI) as compared to healthy subjects. Here we present a two-year follow-up of 14 patients and 12 healthy age-matched subject