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ALDOSTERONE: OBSERVATIONS ON THE REGULATION OF SODIUM AND POTASSIUM BALANCE

1955; American College of Physicians; Volume: 43; Issue: 4 Linguagem: Inglês

10.7326/0003-4819-43-4-658

1539-3704

J A LUETSCHER, R. H. C. Curtis,

Ion Transport and Channel Regulation

Article1 October 1955ALDOSTERONE: OBSERVATIONS ON THE REGULATION OF SODIUM AND POTASSIUM BALANCEJOHN A. LUETSCHER JR., ROBERT H. CURTISJOHN A. LUETSCHER JR., ROBERT H. CURTISAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-4-658 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAccumulation of edema and serous effusions occurs in different clinical patterns, depending on the basic pathology. Changes in capillary pressure or colloid osmotic pressure lead to increase of interstitial fluid at the expense of plasma volume. This process alone would lead to vascular collapse rather than to edema. Retention of ingested sodium and water provides the bulk of edema and may be a useful compensation against falling plasma volume. Sodium retention may be associated with impaired renal blood flow or glomerular filtration, but in most patients the renal tubule appears to exert final control of sodium excretion. The work presented...Bibliography1. DemingLuetscher QBJA: Bioassay of desoxycorticosterone-like material in urine, Proc. Soc. Exper. Biol. and Med. 73: 171, 1950. CrossrefGoogle Scholar2. LuetscherDemingJohnson JAQBBB: The sodium-retaining activity of the corticoid fraction of urine of oedematous patients, Ciba Foundation Colloquia on Endocrinology, Vol. IV, G. E. W. Wolstenholme, Editor, 1952, J. and A. Churchill, London, p. 530. Google Scholar3. TaitSimpsonGrundy JFSAHM: The effect of adrenal extract on mineral metabolism, Lancet 1: 122, 1952. CrossrefMedlineGoogle Scholar4. SimpsonTaitWettsteinNeherv. EuwSchindlerReichstein SAJFARJOT: Die Konstitution des Aldosterons, Helv. chim. Acta 37: 1163, 1954. CrossrefGoogle Scholar5. LuetscherNeherWettstein JARA: Isolation of crystalline aldosterone from the urine of a nephrotic patient, Experientia 10: 456, 1954. CrossrefMedlineGoogle Scholar6. GauntRenziChart RAAJJ: Aldosterone—a review, J. Clin. Endocrinol. and Metab. 15: 621, 1955. CrossrefGoogle Scholar7. WardPolleySlocumbHenchMasonMattoxPower LEHFCHPSHLVRMH: The effects of aldosterone (electrocortin) and of 9α-fluorohydrocortisone acetate on rheumatoid arthritis: preliminary report, Proc. Staff Meet., Mayo Clin. 29: 649, 1954. MedlineGoogle Scholar8. MachFabreDuckertBorthDucommun RSJARP: Clinical and metabolic action of aldosterone (electrocortin), Schweiz. med. Wchnschr. 84: 407, 1954. MedlineGoogle Scholar9. KekwickPawan AGL: Oral aldosterone. Effect in a case of Addison's disease, Lancet 2: 162, 1954. CrossrefGoogle Scholar10. PruntyMcSwineyMillsSmith FTRRIHMA: A study of the effects of aldosterone in Addison's disease and adrenal pseudohermaphroditism, Lancet 2: 620, 1954. CrossrefGoogle Scholar11. ThornSheppardMorseReddyBeigelmanRenold GWRHWIWJPMAE: Comparative action of aldosterone and 9α-fluorohydrocortisone in man, Ann. New York Acad. Sc. 61: 609, 1955. CrossrefMedlineGoogle Scholar12. SimpsonTait SAJF: Some recent advances in methods of isolation and the physiology and chemistry of electrocortin, Recent Progress Hormone Research, in press. Google Scholar13. VenningDyrenfurthGiroud EHIC: Diurnal variation in excretion of a sodium-retaining substance, Federation Proc. 14: 960, 1955. Google Scholar14. LuetscherCurtis JARH: Observations on aldosterone in human urine, Federation Proc., in press. Google Scholar15. AxelradCatesJohnsonLuetscher BJJEBBJA: Aldosterone in urine of normal man and of patients with oedema, Brit. J. Med. 1: 196, 1955. CrossrefMedlineGoogle Scholar16. Johnson BB: Bioassay of adrenal cortical steroids on the basis of electrolyte excretion by rats: effects of 11-desoxy and 11-oxy-steroids, Endocrinology 54: 196, 1954. CrossrefMedlineGoogle Scholar17. ChartShipleyGordon JJEGES: Evidence for a sodium retaining factor in toxemia of pregnancy, Proc. Soc. Exper. Biol. and Med. 78: 244, 1951. CrossrefMedlineGoogle Scholar18. VenningSingerSimpson EGBGA: Adrenocortical function in toxemia of pregnancy, Am. J. Obst. and Gynec. 67: 542, 1954. CrossrefMedlineGoogle Scholar19. LuetscherJohnson JABB: Observations on the sodium-retaining corticoid (aldosterone) in the urine of children and adults in relation to sodium balance and edema, J. Clin. Investigation 33: 1441, 1954. CrossrefMedlineGoogle Scholar20. MacleanLiLipsettRayPearson JPMCMBBOH: The physiological role of adrenal salt hormone (aldosterone) in man, J. Clin. Investigation 34: 951, 1955. Google Scholar21. Conn JW: Primary aldosteronism, a new clinical syndrome, J. Lab. and Clin. Med. 45: 3, 1955. MedlineGoogle Scholar22. MaderIseri IJLT: Spontaneous hypopotassemia, hypomagnesemia, alkalosis and tetany: metabolic and physiologic studies, J. Lab. and Clin. Med. 44: 895, 1954. Google Scholar23. SingerStack-Dunne BMP: Secretion of aldosterone and corticosterone by the rat adrenal, Nature, London 174: 790, 1954. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: San Francisco, California*Presented at the Thirty-sixth Annual Session of The American College of Physicians, Philadelphia, Pennsylvania, April 25, 1955.From the Department of Medicine, Stanford University School of Medicine, San Francisco, California.†This work was supported by a research grant (A-630) from the National Institute of Arthritis and Metabolic Diseases, Public Health Service.‡Trainee of the National Institute of Arthritis and Metabolic Diseases, Public Health Service. 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