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Incorporation of dipalmtoyl phosphatidylcholine into human plasma low density lipoproteins

1980; Elsevier BV; Volume: 619; Issue: 2 Linguagem: Inglês

10.1016/0005-2760(80)90089-2

1879-145X

Richard L. Jackson, Alan D. Cardin, Roger L. Barnhart, J.David Johnson,

Metabolomics and Mass Spectrometry Studies

Bovine liver phosphatidylcholine exchange protein was used to transfer di[14C]palmitoyl phosphatidylcholine from sonicated vesicles to human plasma low density lipoproteins (LDL). The incorporation of di[14C]-palmitoyl phosphatidylcholine into LDL was associated with an increased percentage of total phospholipid and increased lipid rigidity as shown by an increase in the fluorescence polarization of 12-(9-anthroyloxy)-stearic acid and 1,6-diphenyl-1,3,5-hexatriene.