PROBABLE INFECTIOUS MONONUCLEOSIS WITHOUT POSITIVE HETEROPHIL AGGLUTINATION TESTS
1956; American College of Physicians; Volume: 44; Issue: 4 Linguagem: Inglês
10.7326/0003-4819-44-4-717
ISSN1539-3704
Autores Tópico(s)Parvovirus B19 Infection Studies
ResumoArticle1 April 1956PROBABLE INFECTIOUS MONONUCLEOSIS WITHOUT POSITIVE HETEROPHIL AGGLUTINATION TESTSSIDNEY LEIBOWITZ, M.D., F.A.C.P.SIDNEY LEIBOWITZ, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-4-717 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has been the writer's opinion heretofore that all cases of infectious mononucleosis, if properly studied, would reveal positive heterophil agglutination tests. This statement requires some clarification: from the serologic viewpoint a proper study would mean testing for heterophil antibodies at frequent intervals (preferably weekly) for at least three months before the failure to observe a positive test was acceptable. Furthermore, the heterophil agglutination tests should include absorption with guinea pig kidney and beef cell antigens particularly for titers that are, unabsorbed, within the normal range of 1:56 or lower, or within slightly elevated ranges such as 1:112 or 1:224....Bibliography1. Leibowitz S: Infectious mononucleosis: the value of differential absorption tests in its serologic diagnosis, Am. J. Med. 13: 172-182, 1952. CrossrefMedlineGoogle Scholar2. BakstLeibowitz HS: Infectious mononucleosis: first appearance of significant numbers of heterophile antibodies and abnormal lymphocytes ("virocytes") in seventh week of illness. Report of case, Am. J. Med. 13: 235-241, 1952. CrossrefMedlineGoogle Scholar3. Leibowitz S: Infectious mononucleosis, 1953, Grune and Stratton, Inc., New York. Google Scholar4. Leibowitz S: Infectious mononucleosis. Report of a case presenting as acute anaphylactic shock treated with ACTH and cortisone, New York State J. Med. 54: 2711-2716, 1954. MedlineGoogle Scholar5. Bennett IL: The significance of fever in infections, Yale J. Biol. and Med. 26: 491-505, 1954. MedlineGoogle Scholar6. Leibowitz S: Unpublished data. Google Scholar7. LitwinsLeibowitz JS: Abnormal lymphocytes ("virocytes") in virus diseases other than infectious mononucleosis, Acta haemat. 5: 223-231, 1951. CrossrefMedlineGoogle Scholar8. Nolan RA: The nodal triangle, Journal-Lancet 55: 757-759, 1935. Google Scholar9. Leibowitz S: Heterophile antibody in normal adults and patients with virus hepatitis, Am. J. Clin. Path. 21: 201-211, 1951. CrossrefMedlineGoogle Scholar10. HavensGambesciaKnowlton WPJMM: The results of heterophile antibody agglutination and Kahn tests in patients with viral hepatitis, Proc. Soc. Exper. Biol. and Med. 67: 437-440, 1948. CrossrefMedlineGoogle Scholar11. Leibowitz S: Distaste for smoking: an early symptom in virus hepatitis, Rev. Gastroenterol. 16: 721-726, 1949. MedlineGoogle Scholar12. Havens WP: Infectious hepatitis, Medicine 27: 279-326, 1948. CrossrefMedlineGoogle Scholar13. Rodstein M: A case of infectious mononucleosis with atypical pneumonia, Ann. Int. Med. 28: 1177-1187, 1948. LinkGoogle Scholar14. Hirschboeck JS: Unusual manifestations of infectious mononucleosis, Marquette M. Rev. 13: 45-48, 1948. MedlineGoogle Scholar15. CollinsWellsGockeFinland HSEBTMM: Treatment of primary atypical pneumonia with Aureomycin, Am. J. Med. 8: 4-20, 1950. CrossrefMedlineGoogle Scholar16. DuBois AH: De la pathogénie de l'angine à monocytes, Acta med. Scandinav. 73: 237-259, 1930. Google Scholar17. Gooding SE: On glandular fever or infective mononucleosis, Practitioner 127: 468-483, 1931. Google Scholar18. Ziegler EE: Infectious mononucleosis; report of a fatal case with autopsy, Arch. Path. 37: 196-201, 1944. Google Scholar19. WechslerRosenblumSills HFAHCT: Infectious mononucleosis: report of an epidemic in an Army post, Ann. Int. Med. 25: 113-133, 236-265, 1946. LinkGoogle Scholar20. Arendt J: The roentgenological aspect of infectious mononucleosis, Am. J. Roentgenol. 64: 950-958, 1950. Google Scholar21. Cronk GA: Aureomycin in infectious mononucleosis: a control study, Am. J. M. Sc. 222: 413-416, 1951. CrossrefMedlineGoogle Scholar22. StevensBayrdHeck JEEDFJ: Infectious mononucleosis. A study of 210 sporadic cases, Am. J. Med. 11: 202-208, 1951. CrossrefMedlineGoogle Scholar23. SchultzHall ALWH: Clinical observations in 100 cases of infectious mononucleosis and the results of treatment with penicillin and Aureomycin, Ann. Int. Med. 36: 1498-1512, 1952. LinkGoogle Scholar24. SpingarnJones CLJP: Cold hemagglutination in primary atypical pneumonia and other common infections, Arch. Int. Med. 76: 75-87, 1945. CrossrefGoogle Scholar25. GendelCottrell BRJE: Infectious mononuclosis: a review, Am. Pract. 2: 472-478, 1948. Google Scholar26. Hoagland RJ: Infectious mononucleosis, Am. J. Med. 13: 158-171, 1952. CrossrefMedlineGoogle Scholar27. Bender CE: Diagnosis of infectious mononucleosis, J. A. M. A. 149: 7-9 (May 3) 1952. CrossrefMedlineGoogle Scholar28. Bender CE: The value of certain signs in the presumptive diagnosis of infectious mononucleosis, Journal-Lancet 74: 7-10, 1954. MedlineGoogle Scholar29. Tidy H: Glandular fever: infectious mononucleosis, Post-Grad. M. J. 26: 9-15, 1950. CrossrefMedlineGoogle Scholar30. Kimbrough RC: Infectious mononucleosis or a new entity? J. Tennessee M. A. 64: 412-418, 1951. Google Scholar31. Himsworth HP: Vagaries of the Paul-Bunnell test, Lancet 1: 195 (Feb. 8) 1941. CrossrefGoogle Scholar32. Warren EW: Observations in infectious mononucleosis, Am. J. M. Sc. 201: 483-489, 1941. CrossrefGoogle Scholar33. Fuller CJ: Angina of the throat associated with mononucleosis, Lancet 1: 69-71 (Jan. 18) 1941. CrossrefGoogle Scholar34. LyonsHurd HAEM: The effect of Aureomycin therapy in infectious mononucleosis, Bull. New York Acad. Med. 26: 279-280, 1950. Google Scholar35. Davidsohn I: Serologic diagnosis of infectious mononucleosis, J. A. M. A. 108: 289-295 (Jan. 23) 1937. CrossrefGoogle Scholar36. ShubertColleeSmith SJGBJ: Infectious mononucleosis. A syndrome or a disease? Brit. M. J. 1: 671-675, 1954. CrossrefMedlineGoogle Scholar37. BlakeWeltCraige FGLGB: An apparently undescribed infectious exanthem, Yale J. Biol. and Med. 14: 573-579, 1942. MedlineGoogle Scholar38. Thomsen S: Studier over mononucleosis infectiosa, 1942, Ejnar Munksgaard, Copenhagen. Google Scholar39. Sohier R: La mononucléose infectieuse, 1943, Masson et Cie, Paris. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication August 8, 1955.From the Medical Services of Beth Israel Hospital and Bronx Veterans' Administration Hospital.†The author is grateful to Dr. Jay W. Miller for the opportunity to observe this patient and to incorporate the data concerning her in this report. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie infektiöse MononucleoseInfectious Mononucleosis In ChildhoodMononucleosis infectiosa (Pfeiffer’sches Drüsenfieber)Mononucleosis infectiosa (Pfeiffer’sches Drüsenfieber)REFERENCESFever of obscure originDIFFERENTIAL ABSORPTION TESTS IN THE DIAGNOSIS OF INFECTIOUS MONONUCLEOSISINCIDENCE OF INFECTIOUS MONONUCLEOSIS ANTIBODIES IN BLOOD DONORSThe significance of atypical mononuclear leukocytesDie Komplementbindungsreaktion mit einem Lipoidreceptor aus Rindererythrocyten bei der infekti�sen MononucleoseInfectious Mononucleosis and Pseudomononucleosis in ChildhoodNonbacterial Infections Affecting the Nasopharynx 1 April 1956Volume 44, Issue 4Page: 717-737KeywordsAcinetobacterAntibodiesAntigensGuinea pigsHematologic testsKidneysMedical servicesPneumonia ePublished: 1 December 2008 Issue Published: 1 April 1956 PDF downloadLoading ...
Referência(s)