Artigo Revisado por pares

MYXEDEMA HEART: A PATHOLOGICAL AND THERAPEUTIC STUDY

1943; American College of Physicians; Volume: 18; Issue: 3 Linguagem: Inglês

10.7326/0003-4819-18-3-332

ISSN

1539-3704

Autores

John S. La Due,

Tópico(s)

Cardiac electrophysiology and arrhythmias

Resumo

Article1 March 1943MYXEDEMA HEART: A PATHOLOGICAL AND THERAPEUTIC STUDYJOHN S. LA DUE, M.D.JOHN S. LA DUE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-18-3-332 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis report presents the autopsy findings in a patient dying of heart failure due to myxedema and points out the similarity of her myocardial lesions to those found in the beriberi heart. The case history of another patient with myxedema heart treated with thiamin and vitamin B complex and then with thyroid extract is reviewed.The clinical syndrome of heart failure sometimes associated with hypothyroidism (myxedema heart) was first described by Zondek1in 1918. It was later recognized in this country by Fahr2and has since been discussed by many investigators.3Hallock4showed that the cardiac output of the myxedema...Bibliography1. ZONDEK H: Das Myxödemherz, München. med. Wchnschr., 1918, lxv, 1180. Google Scholar2. FAHR G: Myxedema heart, Jr. Am. Med. Assoc., 1925, lxxxiv, 345. CrossrefGoogle Scholar3. ASSMANN H: Das Myxödemherz, München. med. Wchnschr., 1919, lxvi, 9. WILLINS, F., and HAINES, S.: Status of the heart in myxedema, Am. Heart Jr., 1925, i, 67. HOLZMAN, J.: Myxedema heart, Am. Heart Jr., 1929, iv, 351. Google Scholar4. HALLOCK P: The heart in myxedema, with a report of two cases, Am. Heart Jr., 1933, ix, 196. CrossrefGoogle Scholar5. SCHULTZ A: Ueber einen Fall von Athyrosis congenita (Myxödem), Virchow's Arch. f. path. Anat., 1921, ccxxxii, 302. CrossrefGoogle Scholar6. BEHRMÜLDER EJ: Het Myxoedeemhart, Een Pathologisch-Anatomische Bijdrage, Nederl. Tijdschr. v. Geneesk., 1938, lxxxii, 4303. Google Scholar7. WEBSTERCOOKE BC: Morphologic changes in the heart in experimental myxedema, Arch. Int. Med., 1936, lviii, 269. CrossrefGoogle Scholar8. BROOKSLARKIN HJ: A brief experimental study of the morphology of the heart muscle following hypothyroidism, Am. Jr. Med. Sci., 1918, clv, 66. CrossrefGoogle Scholar9. OHLERABRAMSON WJ: The heart in myxedema, Arch. Int. Med., 1934, liii, 165. HIGGINS, W.: The heart in myxedema: correlation of physical and post-mortem findings, Am. Jr. Med. Sci., 1936, cxci, 80. CrossrefGoogle Scholar10. LUFKIN N: Pathologic changes in the heart in myxedema, Jr. Lancet, 1940, lx, 41. Google Scholar11. CEELEN W: Ueber Myxödem, Ziegler's Beitr., 1921, lxix, 342. Google Scholar12. LUFKIN N: Personal Communication. Google Scholar13. WENCKEBACH K: Das Beriberi Herz, 1934, Julius Springer, Berlin and Wien. WENCKEBACH, K.: The riddle of beriberi heart, Libman Anniversary Vol., International Press, New York, 1932, iii, 1199. CrossrefGoogle Scholar14. WEISSWILKINS SR: The nature of cardiovascular disturbances in vitamin deficiency states, Trans. Assoc. Am. Phys., 1936, li, 341. WEISS, S., and WILKINS, R.: The nature of cardiovascular disturbances in nutritional deficiency states (beriberi), ANN. INT. MED., 1937, xi, 104. Google Scholar15. HUNDHAUSEN G: Über die Beziehungen zwischen Avitaminose-B1 und gonadotropem Hormon des Hypophysenvorderlappens, Arch. f. exper. Path. u. Pharmakol., 1939, cxcii, 670. CrossrefGoogle Scholar16. ELMERGIEDOSZSCHEPS ABM: Effects of increased vitamin B1 in experimental hyperthyroidism, Compt.-rend. Soc. de biol., 1937, cxxvi, 1037. Google Scholar17. MITCHELLCARMAN HG: Effects of excessive amounts of vitamin B on basal metabolism, Biol. Abstr., 1927, i, 4693. Google Scholar18. DRILL V: Effect of vitamin B1 and B2 complex on the loss of weight produced in rats by experimental hyperthyroidism, Proc. Soc. Exper. Biol. and Med., 1938, xxxix, 313. CrossrefGoogle Scholar19. LÖHR H: Diätetische und Vitamintherapie des Morbus Basedow, Med. Welt, 1937, xi, 111. Google Scholar20. MEANSHERTZLERMAN JSJ: Nutritional factors in Graves' disease, ANN. INT. MED., 1937, xi, 429. Google Scholar21. FRAZIERRAVDIN WI: The use of vitamin B1 therapy in the preoperative preparation of the hyperthyroid patient, Surgery, 1938, iv, 680. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOHN S. LA DUE, M.D.Affiliations: New Orleans, Louisiana*Received for publication April 22, 1941.From the Department of Medicine at the Minneapolis General Hospital and the University of Minnesota Medical School, Minneapolis, Minnesota. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThyroid and the Heart: A Historical PerspectiveChest Pain in the Setting of Altered Mental StatusA rabbit model of fatal hypothyroidism mimicking “myxedema coma” established by microscopic total thyroidectomyTHE HYPOTHYROID STATESLeft ventricular function at rest and during exercise in acute hypothyroidism.Influence of L-thyroxine on cardiac function in athyreotic thyroid cancer patients — An echophonocardiographic studyCardiac dimensions and myocardial function of infants with congenital hypothyroidism. An echocardiographic study.PERICARDIAL EFFUSION IN HYPOTHYROIDISMCompromise therapy in the patient with angina pectoris and hypothyroidismEchocardiographic characterization of the reversible cardiomyopathy of hypothyroidismNoninvasive Evaluation of Cardiac Function in HypothyroidismCARDIAL COLLOIDMyxedema and Coronary Artery Disease—A Comparative Autopsy StudyALFRED D. STEINBERG, M.D.Serum lactic dehydrogenase isoenzymes in "myxoedema heart disease".The heart in hypothyroidismTHE CARDIOVASCULAR SYSTEM IN THYROID MALFUNCTIONCongestive Heart Failure in Infancy due to HypothyroidismThe Current Status of Procaine Amide in the Management of Cardiac ArrhythmiasFATAL MYXEDEMA, WITH AND WITHOUT COMA*†JOHN F. NICKERSON, S. RICHARDSON HILL JR., M.D., JEAN H. MCNEIL, M.D., SAMUEL B. BARKER, Ph.D.Myxedema ascites: Report of two casesDie Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und HerzinfarktHerz und Kreislauf bei Störungen der SchilddrüsenfunktionHerz und Kreislauf bei Störungen der SchilddrüsenfunktionDas Herz bei Myxödem und HypothyreosePERICARDIAL EFFUSION ASSOCIATED WITH MYXEDEMA*PAUL A. MARKS, M.D., BETTY S. ROOF, M.D.Mean spatial vectorcardiographyNEPHROSIS AND HYPOTHYREOSIS1,2Hypothyroidism and mild myxedema from thiocyanate intoxicationManagement of the myxedematous patient with symptoms of cardiovascular disease 1 March 1943Volume 18, Issue 3 Page: 332-344 Keywords Beriberi Cardiac output Heart Heart failure Hospital medicine Hypothyroidism Lesions Longitudinal studies Thiamine Thyroid ePublished: 1 December 2008 Issue Published: 1 March 1943 PDF downloadLoading ...

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